메뉴 건너뛰기




Volumn 68, Issue 1, 2005, Pages 18-25

Cytochrome P450 and arachidonic acid metabolites: Role in myocardial ischemia/reperfusion injury revisited

Author keywords

Hydroxylase; Arachidonic acid; CYP; Epoxygenase; Infarction; Ischemia; Reperfusion

Indexed keywords

12 HYDROXYICOSATETRAENOIC ACID; 17 OCTADECANOIC ACID; 20 HYDROXYICOSATETRAENOIC ACID; ARACHIDONIC ACID; ASCORBIC ACID; CHLORAMPHENICOL; CIMETIDINE; CLAMIKALANT; CYTOCHROME P450; CYTOCHROME P450 INHIBITOR; DAZMEGREL; DIHYDROXYICOSATRIENOIC ACID; EPOXYICOSATRIENOIC ACID; GLIBENCLAMIDE; HISTAMINE H2 RECEPTOR ANTAGONIST; LIPOXYGENASE; METYRAPONE; MICONAZOLE; N METHYLSULFONYL 12,12 DIBROMODODEC 11 ENAMIDE; N(G) METHYLARGININE; NITRIC OXIDE SYNTHASE INHIBITOR; NITROPRUSSIDE SODIUM; OPIATE; PHOSPHOLIPASE A2; PROSTACYCLIN; PROSTAGLANDIN SYNTHASE; SULFAPHENAZOLE; UNCLASSIFIED DRUG; UNINDEXED DRUG; VASOCONSTRICTOR AGENT; VASODILATOR AGENT;

EID: 24344464401     PISSN: 00086363     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.cardiores.2005.06.007     Document Type: Review
Times cited : (112)

References (53)
  • 1
    • 0030923112 scopus 로고    scopus 로고
    • Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes
    • S. Wu, W. Chen, E. Murphy, S. Gabel, K.B. Tomer, and J. Foley Molecular cloning, expression, and functional significance of a cytochrome P450 highly expressed in rat heart myocytes J Biol Chem 272 1997 12551 12559
    • (1997) J Biol Chem , vol.272 , pp. 12551-12559
    • Wu, S.1    Chen, W.2    Murphy, E.3    Gabel, S.4    Tomer, K.B.5    Foley, J.6
  • 5
    • 0024417919 scopus 로고
    • Synthesis and relevance of cardiac eicosanoids with particular emphasis on ischemia and reperfusion
    • M. Karmazyn Synthesis and relevance of cardiac eicosanoids with particular emphasis on ischemia and reperfusion Can J Physiol Pharmacol 67 1989 912 921
    • (1989) Can J Physiol Pharmacol , vol.67 , pp. 912-921
    • Karmazyn, M.1
  • 6
    • 0028904786 scopus 로고
    • Role of cytochrome P450 enzymes and metabolites of arachidonic acid in the control of vascular tone
    • D. Harder, W.B. Campbell, and R.J. Roman Role of cytochrome P450 enzymes and metabolites of arachidonic acid in the control of vascular tone J Vasc Res 32 1995 79 92
    • (1995) J Vasc Res , vol.32 , pp. 79-92
    • Harder, D.1    Campbell, W.B.2    Roman, R.J.3
  • 7
    • 0025895003 scopus 로고
    • The 1990 Merck Frost award. Ischemic and reperfusion injury in the heart. Cellular mechanisms and pharmacological interventions
    • M. Karmazyn The 1990 Merck Frost award. Ischemic and reperfusion injury in the heart. Cellular mechanisms and pharmacological interventions Can J Physiol Pharmacol 69 1991 719 730
    • (1991) Can J Physiol Pharmacol , vol.69 , pp. 719-730
    • Karmazyn, M.1
  • 9
    • 0024828216 scopus 로고
    • Reflex responses to myocardial ischemia and reperfusion. Role of prostaglandins
    • M.D. Thames, and A.J. Minisi Reflex responses to myocardial ischemia and reperfusion. Role of prostaglandins Circulation 80 1989 1878 1885
    • (1989) Circulation , vol.80 , pp. 1878-1885
    • Thames, M.D.1    Minisi, A.J.2
  • 10
    • 0027501060 scopus 로고
    • Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury
    • T. Hohlfeld, H. Strobach, and K. Schror Stimulation of endogenous prostacyclin protects the reperfused pig myocardium from ischemic injury J Pharmacol Exp Ther 264 1993 397 405
    • (1993) J Pharmacol Exp Ther , vol.264 , pp. 397-405
    • Hohlfeld, T.1    Strobach, H.2    Schror, K.3
  • 11
    • 0027339912 scopus 로고
    • Effects of iloprost, a PGI2 derivative on ischemic myocardial energy and carbohydrate metabolism in dogs
    • K. Ichihara, K. Yamamoto, and Y. Abiko Effects of iloprost, a PGI2 derivative on ischemic myocardial energy and carbohydrate metabolism in dogs Mol Cell Biochem 119 1993 133 141
    • (1993) Mol Cell Biochem , vol.119 , pp. 133-141
    • Ichihara, K.1    Yamamoto, K.2    Abiko, Y.3
  • 12
    • 0028402959 scopus 로고
    • Beneficial effects of iloprost on acute myocardial ischemia in dogs
    • N. Ieda, T. Matsubara, and N. Sakamoto Beneficial effects of iloprost on acute myocardial ischemia in dogs Nagoya J Med Sci 57 1994 25 33
    • (1994) Nagoya J Med Sci , vol.57 , pp. 25-33
    • Ieda, N.1    Matsubara, T.2    Sakamoto, N.3
  • 13
    • 0023907033 scopus 로고
    • Beneficial effects of iloprost in the stunned canine myocardium
    • N. Farber, G.M. Pieper, J.P. Thomas, and G.J. Gross Beneficial effects of iloprost in the stunned canine myocardium Circ Res 62 1988 204 215
    • (1988) Circ Res , vol.62 , pp. 204-215
    • Farber, N.1    Pieper, G.M.2    Thomas, J.P.3    Gross, G.J.4
  • 14
    • 0025064352 scopus 로고
    • Prostaglandin redirection by thromboxane sythetase inhibition. Attenuation of myocardial stunning in canine heart
    • N.E. Farber, and G.J. Gross Prostaglandin redirection by thromboxane sythetase inhibition. Attenuation of myocardial stunning in canine heart Circulation 81 1990 369 380
    • (1990) Circulation , vol.81 , pp. 369-380
    • Farber, N.E.1    Gross, G.J.2
  • 15
    • 0034730120 scopus 로고    scopus 로고
    • Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of preconditioning in conscious rabbits
    • K. Shinmura, X.L. Tang, Y. Wang, Y.T. Xuan, S.Q. Liu, and H. Takano Cyclooxygenase-2 mediates the cardioprotective effects of the late phase of preconditioning in conscious rabbits Proc Natl Acad Sci 97 2000 10197 10202
    • (2000) Proc Natl Acad Sci , vol.97 , pp. 10197-10202
    • Shinmura, K.1    Tang, X.L.2    Wang, Y.3    Xuan, Y.T.4    Liu, S.Q.5    Takano, H.6
  • 16
    • 0034530260 scopus 로고    scopus 로고
    • Evidence for an essential role of cyclooxygenase-2 as a mediator of the late phase of ischemic preconditioning in mice
    • Y. Guo, W. Bao, W.J. Wu, K. Shinmura, X.L. Tang, and R. Bolli Evidence for an essential role of cyclooxygenase-2 as a mediator of the late phase of ischemic preconditioning in mice Basic Res Cardiol 95 2000 479 484
    • (2000) Basic Res Cardiol , vol.95 , pp. 479-484
    • Guo, Y.1    Bao, W.2    Wu, W.J.3    Shinmura, K.4    Tang, X.L.5    Bolli, R.6
  • 17
    • 0037155779 scopus 로고    scopus 로고
    • Inducible nitric oxide synthase modulates cyclooxygenase-2 activity in the heart of conscious rabbits during the late phase of ischemic preconditioning
    • K. Shinmura, Y.T. Xuan, X.L. Tang, E. Kodani, H. Han, and Y. Zhu Inducible nitric oxide synthase modulates cyclooxygenase-2 activity in the heart of conscious rabbits during the late phase of ischemic preconditioning Circ Res 90 2002 602 608
    • (2002) Circ Res , vol.90 , pp. 602-608
    • Shinmura, K.1    Xuan, Y.T.2    Tang, X.L.3    Kodani, E.4    Han, H.5    Zhu, Y.6
  • 19
    • 0035856556 scopus 로고    scopus 로고
    • Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning
    • M.G. Camitta, S.A. Gabel, P. Chulada, J.A. Bradbury, R. Langenbach, and D.C. Zeldin Cyclooxygenase-1 and -2 knockout mice demonstrate increased cardiac ischemia/reperfusion injury but are protected by acute preconditioning Circulation 104 2001 2453 2458
    • (2001) Circulation , vol.104 , pp. 2453-2458
    • Camitta, M.G.1    Gabel, S.A.2    Chulada, P.3    Bradbury, J.A.4    Langenbach, R.5    Zeldin, D.C.6
  • 20
    • 0035030803 scopus 로고    scopus 로고
    • Leukocyte-type 12-lipoxygenase-deficient mice show impaired ischemic preconditioning-induced cardioprotection
    • S.A. Gabel, R.E. London, C.D. Funk, C. Steenbergen, and E. Murphy Leukocyte-type 12-lipoxygenase-deficient mice show impaired ischemic preconditioning-induced cardioprotection Am J Physiol (Heart Circ Physiol) 280 2001 H1963 H1969
    • (2001) Am J Physiol (Heart Circ Physiol) , vol.280
    • Gabel, S.A.1    London, R.E.2    Funk, C.D.3    Steenbergen, C.4    Murphy, E.5
  • 21
    • 0344406762 scopus 로고    scopus 로고
    • Implication of 12-lipoxygenase in opioid-induced delayed cardioprotection by gene array, spectroscopic and pharmacological analyses
    • H.H. Patel, R.M. Fryer, A.K. Hsu, M. Isbell, K. Nithipatikom, and R. Jensen Implication of 12-lipoxygenase in opioid-induced delayed cardioprotection by gene array, spectroscopic and pharmacological analyses Circ Res 92 2003 676 682
    • (2003) Circ Res , vol.92 , pp. 676-682
    • Patel, H.H.1    Fryer, R.M.2    Hsu, A.K.3    Isbell, M.4    Nithipatikom, K.5    Jensen, R.6
  • 22
    • 0028881536 scopus 로고
    • Role of lipoxygenase metabolites in ischemic preconditioning
    • E. Murphy, W. Glasgow, T. Fralix, and C. Steenbergen Role of lipoxygenase metabolites in ischemic preconditioning Circ Res 76 1995 457 467
    • (1995) Circ Res , vol.76 , pp. 457-467
    • Murphy, E.1    Glasgow, W.2    Fralix, T.3    Steenbergen, C.4
  • 23
    • 0029996624 scopus 로고    scopus 로고
    • Effect of ischemic preconditioning and PKC activation on acidification during ischemia in the rat heart
    • W. Chen, W. Wetsel, C. Steenbergen, and E. Murphy Effect of ischemic preconditioning and PKC activation on acidification during ischemia in the rat heart J Mol Cell Cardiol 28 1996 871 880
    • (1996) J Mol Cell Cardiol , vol.28 , pp. 871-880
    • Chen, W.1    Wetsel, W.2    Steenbergen, C.3    Murphy, E.4
  • 24
    • 0033042426 scopus 로고    scopus 로고
    • Lipoxygenase metabolism of arachidonic acid in ischemic preconditioning and PKC-induced protection in heart
    • W. Chen, W. Glasgow, E. Murphy, and C. Steenbergen Lipoxygenase metabolism of arachidonic acid in ischemic preconditioning and PKC-induced protection in heart Am J Physiol (Heart Circ Physiol) 276 1999 H2094 H2101
    • (1999) Am J Physiol (Heart Circ Physiol) , vol.276
    • Chen, W.1    Glasgow, W.2    Murphy, E.3    Steenbergen, C.4
  • 25
    • 0030063499 scopus 로고    scopus 로고
    • Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart
    • S. Wu, C.R. Moomaw, K.B. Tomer, J.R. Falck, and D.C. Zeldin Molecular cloning and expression of CYP2J2, a human cytochrome P450 arachidonic acid epoxygenase highly expressed in heart J Biol Chem 271 1996 3460 3468
    • (1996) J Biol Chem , vol.271 , pp. 3460-3468
    • Wu, S.1    Moomaw, C.R.2    Tomer, K.B.3    Falck, J.R.4    Zeldin, D.C.5
  • 26
    • 0030923112 scopus 로고    scopus 로고
    • Molecular cloning, expression and functional significance of a cytochrome P450 highly expressed in rat heart myocytes
    • S. Wu, W. Chen, E. Murphy, S. Gabel, K.B. Tomer, and C. Steenbergen Molecular cloning, expression and functional significance of a cytochrome P450 highly expressed in rat heart myocytes J Biol Chem 272 1997 12551 12559
    • (1997) J Biol Chem , vol.272 , pp. 12551-12559
    • Wu, S.1    Chen, W.2    Murphy, E.3    Gabel, S.4    Tomer, K.B.5    Steenbergen, C.6
  • 27
    • 0027493771 scopus 로고
    • Molecular cloning, expression and enzymatic characterization of the rat kidney cytochrome P450 arachidonic acid epoxygenase
    • A. Karara, K. Makita, H.R. Jacobson, J.R. Falck, F.P. Guengrich, and R.N. DuBois Molecular cloning, expression and enzymatic characterization of the rat kidney cytochrome P450 arachidonic acid epoxygenase J Biol Chem 268 1993 13565 13570
    • (1993) J Biol Chem , vol.268 , pp. 13565-13570
    • Karara, A.1    Makita, K.2    Jacobson, H.R.3    Falck, J.R.4    Guengrich, F.P.5    Dubois, R.N.6
  • 28
    • 0032476637 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation
    • C.L. Oltman, N.L. Weintraub, M. VanRollins, and K.C. Dellsperger Epoxyeicosatrienoic acids and dihydroxyeicosatrienoic acids are potent vasodilators in the canine coronary microcirculation Circ Res 83 1998 932 939
    • (1998) Circ Res , vol.83 , pp. 932-939
    • Oltman, C.L.1    Weintraub, N.L.2    Vanrollins, M.3    Dellsperger, K.C.4
  • 29
    • 0030051805 scopus 로고    scopus 로고
    • Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
    • W.B. Campbell, D. Gebremedhin, P.F. Pratt, and D.R. Harder Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors Circ Res 78 1996 415 423
    • (1996) Circ Res , vol.78 , pp. 415-423
    • Campbell, W.B.1    Gebremedhin, D.2    Pratt, P.F.3    Harder, D.R.4
  • 30
    • 0035955607 scopus 로고    scopus 로고
    • Cytochrome P450 enzymes in vascular homeostasis
    • I. Fleming Cytochrome P450 enzymes in vascular homeostasis Circ Res 89 2001 753 762
    • (2001) Circ Res , vol.89 , pp. 753-762
    • Fleming, I.1
  • 31
    • 9944254760 scopus 로고    scopus 로고
    • Vascular protective effects of cytochrome P450 epoxygenase-derived eicosanoids
    • M. Spieker, and J.K. Liao Vascular protective effects of cytochrome P450 epoxygenase-derived eicosanoids Arch Biochem Biophys 433 2005 413 420
    • (2005) Arch Biochem Biophys , vol.433 , pp. 413-420
    • Spieker, M.1    Liao, J.K.2
  • 32
    • 0027468198 scopus 로고
    • Effects of epoxyeicosatrienoic acids on isolated hearts and ventricular myocytes
    • M.P. Moffat, C.A. Ward, J.R. Bend, P. Farhangkhoee, and M. Karmazyn Effects of epoxyeicosatrienoic acids on isolated hearts and ventricular myocytes Am J Physiol 264 1993 H1154 H1160
    • (1993) Am J Physiol , vol.264
    • Moffat, M.P.1    Ward, C.A.2    Bend, J.R.3    Farhangkhoee, P.4    Karmazyn, M.5
  • 33
    • 0020586902 scopus 로고
    • Suicide inactivation of rat liver cytochrome P450 by chloramphenicol in vivo and in vitro
    • J. Halpert, B. Naslund, and I. Betner Suicide inactivation of rat liver cytochrome P450 by chloramphenicol in vivo and in vitro Mol Pharmacol 23 1983 445 452
    • (1983) Mol Pharmacol , vol.23 , pp. 445-452
    • Halpert, J.1    Naslund, B.2    Betner, I.3
  • 34
    • 0345356534 scopus 로고    scopus 로고
    • Cytochrome P450: Major player in reperfusion injury
    • R.A. Gottlieb Cytochrome P450: major player in reperfusion injury Arch Biochem Biophys 420 2003 262 267
    • (2003) Arch Biochem Biophys , vol.420 , pp. 262-267
    • Gottlieb, R.A.1
  • 35
    • 1342334719 scopus 로고    scopus 로고
    • Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease
    • S. Fichtlscherer, S. Dimmeler, S. Breuer, R. Busse, A.M. Zeiher, and I. Fleming Inhibition of cytochrome P450 2C9 improves endothelium-dependent, nitric oxide-mediated vasodilatation in patients with coronary artery disease Circulation 109 2004 178 183
    • (2004) Circulation , vol.109 , pp. 178-183
    • Fichtlscherer, S.1    Dimmeler, S.2    Breuer, S.3    Busse, R.4    Zeiher, A.M.5    Fleming, I.6
  • 36
    • 13844309746 scopus 로고    scopus 로고
    • Regulation and inhibition of arachidonic acid omega-hydroxylase and 20-HETE formation
    • D.L. Kroetz, and F. Xu Regulation and inhibition of arachidonic acid omega-hydroxylase and 20-HETE formation Annu Rev Pharmacol Toxicol 45 2005 413 438
    • (2005) Annu Rev Pharmacol Toxicol , vol.45 , pp. 413-438
    • Kroetz, D.L.1    Xu, F.2
  • 37
    • 0031887331 scopus 로고    scopus 로고
    • Cytochrome P450-derived arachidonic acid metabolism in the rat kidney: Characterization of selective inhibitors
    • M.H. Wang, E. Brand-Sceiber, B.A. Zand, X. Nguyen, J.R. Falck, and N. Balu Cytochrome P450-derived arachidonic acid metabolism in the rat kidney: characterization of selective inhibitors J Pharmacol Exp Ther 284 1998 966 973
    • (1998) J Pharmacol Exp Ther , vol.284 , pp. 966-973
    • Wang, M.H.1    Brand-Sceiber, E.2    Zand, B.A.3    Nguyen, X.4    Falck, J.R.5    Balu, N.6
  • 38
  • 39
    • 0029875670 scopus 로고    scopus 로고
    • Metabolism of arachidonic acid by canine polymorphonuclear leukocytes: Synthesis of lipoxygenase and omega-oxidized metabolites
    • M. Rosolowsky, J.R. Falck, and W.B. Campbell Metabolism of arachidonic acid by canine polymorphonuclear leukocytes: synthesis of lipoxygenase and omega-oxidized metabolites Biochem Biophys Acta 130 1996 143 150
    • (1996) Biochem Biophys Acta , vol.130 , pp. 143-150
    • Rosolowsky, M.1    Falck, J.R.2    Campbell, W.B.3
  • 40
    • 0027329156 scopus 로고
    • 20-hydroxyeicosatetranoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries
    • Y.H. Ma, D. Gebremedhin, M.L. Schwartzman, J.R. Falck, J.E. Clark, and B.S. Masters 20-hydroxyeicosatetranoic acid is an endogenous vasoconstrictor of canine renal arcuate arteries Circ Res 72 1993 126 136
    • (1993) Circ Res , vol.72 , pp. 126-136
    • Ma, Y.H.1    Gebremedhin, D.2    Schwartzman, M.L.3    Falck, J.R.4    Clark, J.E.5    Masters, B.S.6
  • 42
  • 43
    • 0031935515 scopus 로고    scopus 로고
    • 20-HETE relaxes bovine coronary arteries through the release of prostacyclin
    • P.F. Pratt, J.R. Falck, K.M. Reddy, J.B. Kurian, and W.B. Campbell 20-HETE relaxes bovine coronary arteries through the release of prostacyclin Hypertension 31 1998 237 241
    • (1998) Hypertension , vol.31 , pp. 237-241
    • Pratt, P.F.1    Falck, J.R.2    Reddy, K.M.3    Kurian, J.B.4    Campbell, W.B.5
  • 44
    • 0035337058 scopus 로고    scopus 로고
    • Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs
    • K. Nithipatikom, R.F. DiCamelli, S. Kohler, R.J. Gumina, J.R. Falck, and W.B. Campbell Determination of cytochrome P450 metabolites of arachidonic acid in coronary venous plasma during ischemia and reperfusion in dogs Anal Biochem 292 2001 115 124
    • (2001) Anal Biochem , vol.292 , pp. 115-124
    • Nithipatikom, K.1    Dicamelli, R.F.2    Kohler, S.3    Gumina, R.J.4    Falck, J.R.5    Campbell, W.B.6
  • 47
    • 0036840527 scopus 로고    scopus 로고
    • + channels by epoxyeicosatrienoic acids: A structural determinant study
    • + channels by epoxyeicosatrienoic acids: a structural determinant study Mol Pharmacol 62 2002 1076 1083
    • (2002) Mol Pharmacol , vol.62 , pp. 1076-1083
    • Lu, T.1    Vanrollins, M.2    Lee, H.C.3
  • 48
    • 0033588325 scopus 로고    scopus 로고
    • 11,12-epoxyeicosatrienoic acid stimulates endogenous mono-ADP ribosylation in bovine coronary arterial smooth muscle
    • P.L. Li, C.L. Chen, R. Bortell, and W.B. Campbell 11,12- epoxyeicosatrienoic acid stimulates endogenous mono-ADP ribosylation in bovine coronary arterial smooth muscle Circ Res 85 1999 349 356
    • (1999) Circ Res , vol.85 , pp. 349-356
    • Li, P.L.1    Chen, C.L.2    Bortell, R.3    Campbell, W.B.4
  • 49
    • 0242720683 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids (EETs): Metabolism and biochemical function
    • A.A. Spector, X. Fang, G.D. Snyder, and N.L. Weintraub Epoxyeicosatrienoic acids (EETs): metabolism and biochemical function Prog Lipid Res 43 2004 55 90
    • (2004) Prog Lipid Res , vol.43 , pp. 55-90
    • Spector, A.A.1    Fang, X.2    Snyder, G.D.3    Weintraub, N.L.4
  • 50
    • 0032478779 scopus 로고    scopus 로고
    • 11,12-epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells
    • B.G. Hoebel, and W.F. Graier 11,12-epoxyeicosatrienoic acid stimulates tyrosine kinase activity in porcine aortic endothelial cells Eur J Pharmacol 346 1998 115 117
    • (1998) Eur J Pharmacol , vol.346 , pp. 115-117
    • Hoebel, B.G.1    Graier, W.F.2
  • 51
    • 16844371392 scopus 로고    scopus 로고
    • 5-enkephalin-induced cardioprotection occurs via transactivation of EGFR and activation of PI3K
    • 5-enkephalin-induced cardioprotection occurs via transactivation of EGFR and activation of PI3K Am J Physiol 288 2005 H1955 H1964
    • (2005) Am J Physiol , vol.288
    • Cao, Z.1    Liu, L.2    Van Winkle, D.M.3
  • 52
    • 0033588034 scopus 로고    scopus 로고
    • Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids
    • K. Node, Y. Huo, X. Ruan, B. Yang, M. Spieker, and K. Ley Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids Science 285 1999 1276 1279
    • (1999) Science , vol.285 , pp. 1276-1279
    • Node, K.1    Huo, Y.2    Ruan, X.3    Yang, B.4    Spieker, M.5    Ley, K.6
  • 53
    • 0034176077 scopus 로고    scopus 로고
    • New role for epoxyeicosatrienoic acids as anti-inflammatory mediators
    • W.B. Campbell New role for epoxyeicosatrienoic acids as anti-inflammatory mediators Trends Pharmacol Sci 21 2000 125 127
    • (2000) Trends Pharmacol Sci , vol.21 , pp. 125-127
    • Campbell, W.B.1


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.