-
1
-
-
0036209248
-
Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor
-
Kliewer S.A., Willson T.M. Regulation of xenobiotic and bile acid metabolism by the nuclear pregnane X receptor. J. Lipid Res. 43:2002;359-364.
-
(2002)
J. Lipid Res.
, vol.43
, pp. 359-364
-
-
Kliewer, S.A.1
Willson, T.M.2
-
2
-
-
0036799870
-
The nuclear pregnane X receptor: A key regulator of xenobiotic metabolism
-
Kliewer S.A., Goodwin B., Willson T.M. The nuclear pregnane X receptor: a key regulator of xenobiotic metabolism. Endocr. Rev. 23:2002;687-702.
-
(2002)
Endocr. Rev.
, vol.23
, pp. 687-702
-
-
Kliewer, S.A.1
Goodwin, B.2
Willson, T.M.3
-
3
-
-
0037169551
-
Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor
-
Kast H.R., Goodwin B., Tarr P.T., Jones S.A., Anisfeld A.M., Stoltz C.M., Tontonoz P., Kliewer S., Willson T.M., Edwards P.A. Regulation of multidrug resistance-associated protein 2 (ABCC2) by the nuclear receptors pregnane X receptor, farnesoid X-activated receptor, and constitutive androstane receptor. J. Biol. Chem. 277:2002;2908-2915.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 2908-2915
-
-
Kast, H.R.1
Goodwin, B.2
Tarr, P.T.3
Jones, S.A.4
Anisfeld, A.M.5
Stoltz, C.M.6
Tontonoz, P.7
Kliewer, S.8
Willson, T.M.9
Edwards, P.A.10
-
4
-
-
0035029401
-
The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR
-
Sugatani J., Kojima H., Ueda A., Kakizaki S., Yoshinari K., Gong Q.H., Owens I.S., Negishi M., Sueyoshi T. The phenobarbital response enhancer module in the human bilirubin UDP-glucuronosyltransferase UGT1A1 gene and regulation by the nuclear receptor CAR. Hepatology. 33:2001;1232-1238.
-
(2001)
Hepatology
, vol.33
, pp. 1232-1238
-
-
Sugatani, J.1
Kojima, H.2
Ueda, A.3
Kakizaki, S.4
Yoshinari, K.5
Gong, Q.H.6
Owens, I.S.7
Negishi, M.8
Sueyoshi, T.9
-
5
-
-
0036765785
-
Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification
-
Maglich J.M., Stoltz C.M., Goodwin B., Hawkins-Brown D., Moore J.T., Kliewer S.A. Nuclear pregnane X receptor and constitutive androstane receptor regulate overlapping but distinct sets of genes involved in xenobiotic detoxification. Mol. Pharmacol. 62:2002;638-646.
-
(2002)
Mol. Pharmacol.
, vol.62
, pp. 638-646
-
-
Maglich, J.M.1
Stoltz, C.M.2
Goodwin, B.3
Hawkins-Brown, D.4
Moore, J.T.5
Kliewer, S.A.6
-
6
-
-
0032169485
-
The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions
-
Lehmann J.M., McKee D.D., Watson M.A., Willson T.M., Moore J.T., Kliewer S.A. The human orphan nuclear receptor PXR is activated by compounds that regulate CYP3A4 gene expression and cause drug interactions. J. Clin. Invest. 102:1998;1016-1023.
-
(1998)
J. Clin. Invest.
, vol.102
, pp. 1016-1023
-
-
Lehmann, J.M.1
McKee, D.D.2
Watson, M.A.3
Willson, T.M.4
Moore, J.T.5
Kliewer, S.A.6
-
7
-
-
0033574663
-
A unified nomenclature system for the nuclear receptor superfamily
-
A unified nomenclature system for the nuclear receptor superfamily. Cell 97 (1999) 161-163.
-
(1999)
Cell
, vol.97
, pp. 161-163
-
-
-
8
-
-
0035224757
-
Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes
-
Maglich J.M., Sluder A., Guan X., Shi Y., McKee D.D., Carrick K., Kamdar K., Willson T.M., Moore J.T. Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes. Genome Biol. 2:2001;1-7.
-
(2001)
Genome Biol.
, vol.2
, pp. 1-7
-
-
Maglich, J.M.1
Sluder, A.2
Guan, X.3
Shi, Y.4
McKee, D.D.5
Carrick, K.6
Kamdar, K.7
Willson, T.M.8
Moore, J.T.9
-
9
-
-
0028210426
-
A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements
-
Baes M., Gulick T., Choi H.S., Martinoli M.G., Simha D., Moore D.D. A new orphan member of the nuclear hormone receptor superfamily that interacts with a subset of retinoic acid response elements. Mol. Cell. Biol. 14:1994;1544-1551.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 1544-1551
-
-
Baes, M.1
Gulick, T.2
Choi, H.S.3
Martinoli, M.G.4
Simha, D.5
Moore, D.D.6
-
10
-
-
0030802649
-
Differential transactivation by two isoforms of the orphan nuclear hormone receptor CAR
-
Choi H.S., Chung M., Tzameli I., Simha D., Lee Y.K., Seol W., Moore D.D. Differential transactivation by two isoforms of the orphan nuclear hormone receptor CAR. J. Biol. Chem. 272:1997;23565-23571.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 23565-23571
-
-
Choi, H.S.1
Chung, M.2
Tzameli, I.3
Simha, D.4
Lee, Y.K.5
Seol, W.6
Moore, D.D.7
-
11
-
-
0031682988
-
The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene
-
Honkakoski P., Zelko I., Sueyoshi T., Negishi M. The nuclear orphan receptor CAR-retinoid X receptor heterodimer activates the phenobarbital-responsive enhancer module of the CYP2B gene. Mol. Cell. Biol. 18:1998;5652-5658.
-
(1998)
Mol. Cell. Biol.
, vol.18
, pp. 5652-5658
-
-
Honkakoski, P.1
Zelko, I.2
Sueyoshi, T.3
Negishi, M.4
-
12
-
-
0032766430
-
Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene
-
Kawamoto T., Sueyoshi T., Zelko I., Moore R., Washburn K., Negishi M. Phenobarbital-responsive nuclear translocation of the receptor CAR in induction of the CYP2B gene. Mol. Cell. Biol. 19:1999;6318-6322.
-
(1999)
Mol. Cell. Biol.
, vol.19
, pp. 6318-6322
-
-
Kawamoto, T.1
Sueyoshi, T.2
Zelko, I.3
Moore, R.4
Washburn, K.5
Negishi, M.6
-
13
-
-
0035076197
-
The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver
-
Zelko I., Sueyoshi T., Kawamoto T., Moore R., Negishi M. The peptide near the C terminus regulates receptor CAR nuclear translocation induced by xenochemicals in mouse liver. Mol. Cell. Biol. 21:2001;2838-2846.
-
(2001)
Mol. Cell. Biol.
, vol.21
, pp. 2838-2846
-
-
Zelko, I.1
Sueyoshi, T.2
Kawamoto, T.3
Moore, R.4
Negishi, M.5
-
14
-
-
0036256351
-
Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors
-
Moore L.B., Maglich J.M., McKee D.D., Wisely B., Willson T.M., Kliewer S.A., Lambert M.H., Moore J.T. Pregnane X receptor (PXR), constitutive androstane receptor (CAR), and benzoate X receptor (BXR) define three pharmacologically distinct classes of nuclear receptors. Mol. Endocrinol. 16:2002;977-986.
-
(2002)
Mol. Endocrinol.
, vol.16
, pp. 977-986
-
-
Moore, L.B.1
Maglich, J.M.2
McKee, D.D.3
Wisely, B.4
Willson, T.M.5
Kliewer, S.A.6
Lambert, M.H.7
Moore, J.T.8
-
15
-
-
0033999734
-
The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR
-
Tzameli I., Pissios P., Schuetz E.G., Moore D.D. The xenobiotic compound 1,4-bis[2-(3,5-dichloropyridyloxy)]benzene is an agonist ligand for the nuclear receptor CAR. Mol. Cell. Biol. 20:2000;2951-2958.
-
(2000)
Mol. Cell. Biol.
, vol.20
, pp. 2951-2958
-
-
Tzameli, I.1
Pissios, P.2
Schuetz, E.G.3
Moore, D.D.4
-
16
-
-
0032497544
-
Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta
-
Forman B.M., Tzameli I., Choi H.S., Chen J., Simha D., Seol W., Evans R.M., Moore D.D. Androstane metabolites bind to and deactivate the nuclear receptor CAR-beta. Nature. 395:1998;612-615.
-
(1998)
Nature
, vol.395
, pp. 612-615
-
-
Forman, B.M.1
Tzameli, I.2
Choi, H.S.3
Chen, J.4
Simha, D.5
Seol, W.6
Evans, R.M.7
Moore, D.D.8
-
17
-
-
0037135532
-
Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo
-
Min G., Kemper J.K., Kemper B. Glucocorticoid receptor-interacting protein 1 mediates ligand-independent nuclear translocation and activation of constitutive androstane receptor in vivo. J. Biol. Chem. 277:2002;26356-26363.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 26356-26363
-
-
Min, G.1
Kemper, J.K.2
Kemper, B.3
-
18
-
-
0037931737
-
Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes
-
Maglich J.M., Parks D.J., Moore L.B., Collins J.L., Goodwin B., Billin A.N., Stoltz C.A., Kliewer S.A., Lambert M.H., Willson T.M., Moore J.T. Identification of a novel human constitutive androstane receptor (CAR) agonist and its use in the identification of CAR target genes. J. Biol. Chem. 278:2003;17277-17283.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 17277-17283
-
-
Maglich, J.M.1
Parks, D.J.2
Moore, L.B.3
Collins, J.L.4
Goodwin, B.5
Billin, A.N.6
Stoltz, C.A.7
Kliewer, S.A.8
Lambert, M.H.9
Willson, T.M.10
Moore, J.T.11
-
19
-
-
0034685779
-
Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands
-
Moore L.B., Parks D.J., Jones S.A., Bledsoe R.K., Consler T.G., Stimmel J.B., Goodwin B., Liddle C., Blanchard S.G., Willson T.M., Collins J.L., Kliewer S.A. Orphan nuclear receptors constitutive androstane receptor and pregnane X receptor share xenobiotic and steroid ligands. J. Biol. Chem. 275:2000;15122-15127.
-
(2000)
J. Biol. Chem.
, vol.275
, pp. 15122-15127
-
-
Moore, L.B.1
Parks, D.J.2
Jones, S.A.3
Bledsoe, R.K.4
Consler, T.G.5
Stimmel, J.B.6
Goodwin, B.7
Liddle, C.8
Blanchard, S.G.9
Willson, T.M.10
Collins, J.L.11
Kliewer, S.A.12
-
20
-
-
2042437650
-
Initial sequencing and analysis of the human genome
-
Lander E.S., Linton L.M., Birren B.et al. Initial sequencing and analysis of the human genome. Nature. 409:2001;860-921.
-
(2001)
Nature
, vol.409
, pp. 860-921
-
-
Lander, E.S.1
Linton, L.M.2
Birren, B.3
-
21
-
-
0036337915
-
A genomic view of alternative splicing
-
Modrek B., Lee C. A genomic view of alternative splicing. Nat. Genet. 30:2002;13-19.
-
(2002)
Nat. Genet.
, vol.30
, pp. 13-19
-
-
Modrek, B.1
Lee, C.2
-
22
-
-
0037088644
-
Requirement of helix 1 and the AF-2 domain of the thyroid hormone receptor for coactivation by PGC-1
-
Wu Y.F., Delerive P., Chin W.W., Burris T.P. Requirement of helix 1 and the AF-2 domain of the thyroid hormone receptor for coactivation by PGC-1. J. Biol. Chem. 277:2002;8898-8905.
-
(2002)
J. Biol. Chem.
, vol.277
, pp. 8898-8905
-
-
Wu, Y.F.1
Delerive, P.2
Chin, W.W.3
Burris, T.P.4
-
23
-
-
0027136282
-
Comparative protein modelling by satisfaction of spatial restraints
-
Sali A., Blundell T.L. Comparative protein modelling by satisfaction of spatial restraints. J. Mol. Biol. 234:1993;779-815.
-
(1993)
J. Mol. Biol.
, vol.234
, pp. 779-815
-
-
Sali, A.1
Blundell, T.L.2
-
24
-
-
0037389946
-
Induction of bilirubin clearance by the constitutive androstane receptor (CAR)
-
Huang W., Zhang J., Chua S.S., Qatanani M., Han Y., Granata R., Moore D.D. Induction of bilirubin clearance by the constitutive androstane receptor (CAR). Proc. Natl. Acad. Sci. USA. 100:2003;4156-4161.
-
(2003)
Proc. Natl. Acad. Sci. USA
, vol.100
, pp. 4156-4161
-
-
Huang, W.1
Zhang, J.2
Chua, S.S.3
Qatanani, M.4
Han, Y.5
Granata, R.6
Moore, D.D.7
-
25
-
-
0035933511
-
The human nuclear xenobiotic receptor PXR: Structural determinants of directed promiscuity
-
Watkins R.E., Wisely G.B., Moore L.B., Collins J.L., Lambert M.H., Williams S.P., Willson T.M., Kliewer S.A., Redinbo M.R. The human nuclear xenobiotic receptor PXR: structural determinants of directed promiscuity. Science. 292:2001;2329-2333.
-
(2001)
Science
, vol.292
, pp. 2329-2333
-
-
Watkins, R.E.1
Wisely, G.B.2
Moore, L.B.3
Collins, J.L.4
Lambert, M.H.5
Williams, S.P.6
Willson, T.M.7
Kliewer, S.A.8
Redinbo, M.R.9
-
26
-
-
0033963897
-
The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand
-
Rochel N., Wurtz J.M., Mitschler A., Klaholz B., Moras D. The crystal structure of the nuclear receptor for vitamin D bound to its natural ligand. Mol. Cell. 5:2000;173-179.
-
(2000)
Mol. Cell
, vol.5
, pp. 173-179
-
-
Rochel, N.1
Wurtz, J.M.2
Mitschler, A.3
Klaholz, B.4
Moras, D.5
-
27
-
-
0017166105
-
Status of empirical methods for the prediction of protein backbone topography
-
Maxfield F.R., Scheraga H.A. Status of empirical methods for the prediction of protein backbone topography. Biochemistry. 15:1976;5138-5153.
-
(1976)
Biochemistry
, vol.15
, pp. 5138-5153
-
-
Maxfield, F.R.1
Scheraga, H.A.2
-
28
-
-
0017873321
-
Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins
-
Garnier J., Osguthorpe D.J., Robson B. Analysis of the accuracy and implications of simple methods for predicting the secondary structure of globular proteins. J. Mol. Biol. 120:1978;97-120.
-
(1978)
J. Mol. Biol.
, vol.120
, pp. 97-120
-
-
Garnier, J.1
Osguthorpe, D.J.2
Robson, B.3
-
29
-
-
0023803244
-
Predicting the secondary structure of globular proteins using neural network models
-
Qian N., Sejnowski T.J. Predicting the secondary structure of globular proteins using neural network models. J. Mol. Biol. 202:1988;865-884.
-
(1988)
J. Mol. Biol.
, vol.202
, pp. 865-884
-
-
Qian, N.1
Sejnowski, T.J.2
-
30
-
-
0037563788
-
Alternatively spliced isoforms of the human constitutive androstane receptor
-
Auerbach S.S., Ramsden R., Stoner M.A., Verlinde C., Hassett C., Omiecinski C.J. Alternatively spliced isoforms of the human constitutive androstane receptor. Nucleic Acids Res. 31:2003;3194-3207.
-
(2003)
Nucleic Acids Res.
, vol.31
, pp. 3194-3207
-
-
Auerbach, S.S.1
Ramsden, R.2
Stoner, M.A.3
Verlinde, C.4
Hassett, C.5
Omiecinski, C.J.6
-
31
-
-
0026600841
-
Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors
-
Danielian P.S., White R., Lees J.A., Parker M.G. Identification of a conserved region required for hormone dependent transcriptional activation by steroid hormone receptors. EMBO J. 11:1992;1025-1033.
-
(1992)
EMBO J.
, vol.11
, pp. 1025-1033
-
-
Danielian, P.S.1
White, R.2
Lees, J.A.3
Parker, M.G.4
-
32
-
-
0028988482
-
The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing
-
Baniahmad A., Leng X., Burris T.P., Tsai S.Y., Tsai M.J., O'Malley B.W. The tau 4 activation domain of the thyroid hormone receptor is required for release of a putative corepressor(s) necessary for transcriptional silencing. Mol. Cell. Biol. 15:1995;76-86.
-
(1995)
Mol. Cell. Biol.
, vol.15
, pp. 76-86
-
-
Baniahmad, A.1
Leng, X.2
Burris, T.P.3
Tsai, S.Y.4
Tsai, M.J.5
O'Malley, B.W.6
-
33
-
-
0028233763
-
Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor
-
Barettino D., Vivanco-Ruiz M.M., Stunnenberg H.G. Characterization of the ligand-dependent transactivation domain of thyroid hormone receptor. EMBO J. 13:1994;3039-3049.
-
(1994)
EMBO J.
, vol.13
, pp. 3039-3049
-
-
Barettino, D.1
Vivanco-Ruiz, M.M.2
Stunnenberg, H.G.3
-
34
-
-
0028348240
-
Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor alpha
-
Tate B.F., Allenby G., Janocha R., Kazmer S., Speck J., Sturzenbecker L.J., Abarzua P., Levin A.A., Grippo J.F. Distinct binding determinants for 9-cis retinoic acid are located within AF-2 of retinoic acid receptor alpha. Mol. Cell. Biol. 14:1994;2323-2330.
-
(1994)
Mol. Cell. Biol.
, vol.14
, pp. 2323-2330
-
-
Tate, B.F.1
Allenby, G.2
Janocha, R.3
Kazmer, S.4
Speck, J.5
Sturzenbecker, L.J.6
Abarzua, P.7
Levin, A.A.8
Grippo, J.F.9
-
35
-
-
0013394889
-
Mechanisms of alternative pre-messenger RNA splicing
-
Black D.L. Mechanisms of alternative pre-messenger RNA splicing. Annu. Rev. Biochem. 72:2003;291-336.
-
(2003)
Annu. Rev. Biochem.
, vol.72
, pp. 291-336
-
-
Black, D.L.1
|