Role of reactive oxygen intermediates in the decrease of hepatic cytochrome P450 activity by serum of humans and rabbits with an acute inflammatory reaction

Drug Metabolism and Disposition

Volumn 28, Issue 9, 2000, Pages 1112-1120

  El Kadi, Ayman O S ^a   Bleau, Anne Marie ^a   Dumont, Isabelle ^a   Maurice, Hélène ^a   Du Souich, Patrick ^a  

^a UNIVERSITÉ DE MONTRÉAL   (Canada)

Author keywords

[No Author keywords available]

Indexed keywords

1,3 DIMETHYLURIC ACID; ACETYLCYSTEINE; AMITROLE; ANTIOXIDANT; BUTHIONINE SULFOXIMINE; CYTOCHROME P450; DIETHYLDITHIOCARBAMIC ACID; DIMETHYLTHIOUREA; DRUG METABOLITE; HYDROGEN PEROXIDE; N(G) NITROARGININE METHYL ESTER; NITROPRUSSIDE SODIUM; REACTIVE OXYGEN METABOLITE; THEOPHYLLINE;

ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; ENZYME INACTIVATION; HUMAN; INFLAMMATION; LIPID PEROXIDATION; LIVER CELL; MALE; NONHUMAN; PRIORITY JOURNAL; RABBIT; SERUM; VIRUS INFECTION;

ACUTE-PHASE REACTION; AMITROLE; ANIMALS; BIOTRANSFORMATION; BUTHIONINE SULFOXIMINE; CYTOCHROME P-450 ENZYME SYSTEM; DITIOCARB; DOSE-RESPONSE RELATIONSHIP, DRUG; ENZYME INHIBITORS; FREE RADICAL SCAVENGERS; HUMANS; HYDROGEN PEROXIDE; LIVER; MALE; NG-NITROARGININE METHYL ESTER; NITROPRUSSIDE; RABBITS; REACTIVE OXYGEN SPECIES; THEOPHYLLINE; THIOUREA;

EID: 0033844631     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article

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