Interindividual variability and tissue-specificity in the expression of cytochrome P450 3a mRNA

Drug Metabolism and Disposition

Volumn 30, Issue 10, 2002, Pages 1108-1114

  Koch, Ina ^a   Weil, Regina ^b   Wolbold, Renzo ^c   Brockmöller, Jürgen ^d   Hustert, Elisabeth ^a   Burk, Oliver ^a   Nuessler, Andreas ^b   Neuhaus, Peter ^b   Eichelbaum, Michel ^b   Zanger, Ulrich ^a   Wojnowski, Leszek ^a  

^a Epidauros Biotechnologie AG   (Germany)

^b DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

^c UNIVERSITY OF GÖTTINGEN   (Germany)

^d CHARITÉ UNIVERSITÄTSMEDIZIN BERLIN   (Germany)

Author keywords

[No Author keywords available]

Indexed keywords

CYTOCHROME P450 3A; CYTOCHROME P450 3A4; CYTOCHROME P450 3A43; CYTOCHROME P450 3A5; CYTOCHROME P450 3A7; MESSENGER RNA; PREGNANE X RECEPTOR; UNCLASSIFIED DRUG;

ADRENAL GLAND; ALLELE; ARTICLE; BIOASSAY; CAUCASIAN; CONTROLLED STUDY; DNA PROBE; DOMINANT GENE; ENZYME ACTIVITY; ENZYME POLYMORPHISM; GENE EXPRESSION REGULATION; GENE FUNCTION; GENE POOL; GENE SEQUENCE; GENETIC VARIABILITY; HETEROZYGOTE; HUMAN; HUMAN CELL; HUMAN TISSUE; INTESTINE; KIDNEY; LIVER; MARKER GENE; PERIPHERAL LYMPHOCYTE; PRIORITY JOURNAL; PROSTATE; PROTEIN EXPRESSION; REVERSE TRANSCRIPTION; TISSUE DISTRIBUTION; TISSUE SPECIFICITY;

CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION; HUMANS; ISOENZYMES; LIVER; ORGAN SPECIFICITY; RNA, MESSENGER; VARIATION (GENETICS);

STAPHYLOCOCCUS PHAGE 3A;

EID: 0036786382     PISSN: 00909556     EISSN: None     Source Type: Journal    
DOI: 10.1124/dmd.30.10.1108     Document Type: Article

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