-
1
-
-
0002255855
-
Debrisoquine/sparteine monooxygenase and other P450s in the brain
-
(W. Kalow, ed.). Pergamon Press, New York
-
Kalow, W., and R. Tyndale. Debrisoquine/sparteine monooxygenase and other P450s in the brain, in Pharmacogenetics of Drug Metabolism (W. Kalow, ed.). Pergamon Press, New York, 649-656 (1992).
-
(1992)
Pharmacogenetics of Drug Metabolism
, pp. 649-656
-
-
Kalow, W.1
Tyndale, R.2
-
2
-
-
0000858780
-
Extrahepatic microsomal forms: Brain cytochrome P450
-
(J. Schenkman, ed.). Springer Verlag, Berlin
-
Warner, M., and J.-A. Gustafsson. Extrahepatic microsomal forms: brain cytochrome P450, in Handbook of Experimental Pharmacology: Cytochrome P450 (J. Schenkman, ed.). Springer Verlag, Berlin, 387-397 (1993).
-
(1993)
Handbook of Experimental Pharmacology: Cytochrome P450
, pp. 387-397
-
-
Warner, M.1
Gustafsson, J.-A.2
-
3
-
-
0025356936
-
Regional distribution of cytochrome P450 2E1 in the rat central nervous system
-
Hansson T., N. Tindberg, M. Ingelman-Sundberg, and C. Köhler. Regional distribution of cytochrome P450 2E1 in the rat central nervous system. Neuroscience 34:451-463 (1990).
-
(1990)
Neuroscience
, vol.34
, pp. 451-463
-
-
Hansson, T.1
Tindberg, N.2
Ingelman-Sundberg, M.3
Köhler, C.4
-
4
-
-
0029823019
-
Expression, catalytic activity and inducibility of CYP2E1 in the rat central nervous system
-
in press
-
Tindberg, N., and M. Ingelman-Sundberg. Expression, catalytic activity and inducibility of CYP2E1 in the rat central nervous system. J. Neurochem., in press (1996).
-
(1996)
J. Neurochem.
-
-
Tindberg, N.1
Ingelman-Sundberg, M.2
-
5
-
-
0026501942
-
Sequence identification of 2,375 human brain genes
-
Adams, M. D., M. Dubnick, A. R. Kerlavage, R. Moreno, J. M. Kelley, T. R. Utterback, J. W. Nagle, C. Fields, and J. C. Venter. Sequence identification of 2,375 human brain genes. Nature (Lond.) 355:632-634 (1992).
-
(1992)
Nature (Lond.)
, vol.355
, pp. 632-634
-
-
Adams, M.D.1
Dubnick, M.2
Kerlavage, A.R.3
Moreno, R.4
Kelley, J.M.5
Utterback, T.R.6
Nagle, J.W.7
Fields, C.8
Venter, J.C.9
-
6
-
-
0027515708
-
Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane and methoxyflurane
-
Kharasch, E. D., and K. E. Thummel. Identification of cytochrome P450 2E1 as the predominant enzyme catalyzing human liver microsomal defluorination of sevoflurane, isoflurane and methoxyflurane. Anesthesiology 79:795-807 (1993)
-
(1993)
Anesthesiology
, vol.79
, pp. 795-807
-
-
Kharasch, E.D.1
Thummel, K.E.2
-
7
-
-
0000752134
-
Isozyme-specificity of cytochrome P450 mediated hepatotoxicity
-
Terelius, Y., K. O. Lindros, E. Albano, and M. Ingelman-Sundberg. Isozyme-specificity of cytochrome P450 mediated hepatotoxicity. Front. Biotransform. 8:187-232 (1992).
-
(1992)
Front. Biotransform.
, vol.8
, pp. 187-232
-
-
Terelius, Y.1
Lindros, K.O.2
Albano, E.3
Ingelman-Sundberg, M.4
-
8
-
-
0025223625
-
Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P450 2E1
-
Peter, R., R. Böcker, P. H. Beaune, M. Iwasaki, F. P. Guengerich, and C. S. Yang. Hydroxylation of chlorzoxazone as a specific probe for human liver cytochrome P450 2E1. Chem. Res. Toxicol. 3:566-573 (1990).
-
(1990)
Chem. Res. Toxicol.
, vol.3
, pp. 566-573
-
-
Peter, R.1
Böcker, R.2
Beaune, P.H.3
Iwasaki, M.4
Guengerich, F.P.5
Yang, C.S.6
-
9
-
-
0027164207
-
Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1
-
Laethem, R. M., M. Balazy, J. R. Falck, C. L. Laethem, and D. R. Koop. Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome P450 2E1. J. Biol. Chem. 268:12912-12918 (1993).
-
(1993)
J. Biol. Chem.
, vol.268
, pp. 12912-12918
-
-
Laethem, R.M.1
Balazy, M.2
Falck, J.R.3
Laethem, C.L.4
Koop, D.R.5
-
10
-
-
0002077288
-
The cytochrome P4502E subfamily
-
(I. Ioannides, ed.) CRC Press, Boca Raton, Florida, in press
-
Ronis, M. J. J., K. O. Lindros, and M. Ingelman-Sundberg. The cytochrome P4502E subfamily, in Cytochromes P450, Pharmacological and Toxicological Aspects (I. Ioannides, ed.) CRC Press, Boca Raton, Florida, in press (1996).
-
(1996)
Cytochromes P450, Pharmacological and Toxicological Aspects
-
-
Ronis, M.J.J.1
Lindros, K.O.2
Ingelman-Sundberg, M.3
-
11
-
-
0024386439
-
Cytochrome P450 and oxygen toxicity. Oxygen-dependent induction of cytochrome P450 2E1 in rat liver and lung
-
Tindberg, N., and M. Ingelman-Sundberg. Cytochrome P450 and oxygen toxicity. Oxygen-dependent induction of cytochrome P450 2E1 in rat liver and lung. Biochemistry 28:4499-4504 (1989).
-
(1989)
Biochemistry
, vol.28
, pp. 4499-4504
-
-
Tindberg, N.1
Ingelman-Sundberg, M.2
-
12
-
-
0029112792
-
Rationale for therapy for alcoholic liver disease
-
French, S. W. Rationale for therapy for alcoholic liver disease. Gastroenterology 109:617-20 (1995).
-
(1995)
Gastroenterology
, vol.109
, pp. 617-620
-
-
French, S.W.1
-
13
-
-
0001139213
-
Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus
-
Lieberman, A. P., P. M. Pitha, H. S. Shin, and M. L. Shin. Production of tumor necrosis factor and other cytokines by astrocytes stimulated with lipopolysaccharide or a neurotropic virus. Proc. Natl. Acad. Sci. USA 86:6348-6352 (1989).
-
(1989)
Proc. Natl. Acad. Sci. USA
, vol.86
, pp. 6348-6352
-
-
Lieberman, A.P.1
Pitha, P.M.2
Shin, H.S.3
Shin, M.L.4
-
14
-
-
0026774797
-
Induction of nitric oxide synthase in glial cells
-
Simmons, M. L., and S. Murphy. Induction of nitric oxide synthase in glial cells. J. Neurochem. 59:897-905 (1992).
-
(1992)
J. Neurochem.
, vol.59
, pp. 897-905
-
-
Simmons, M.L.1
Murphy, S.2
-
15
-
-
0025895754
-
2 in rat cultured astrocytes
-
2 in rat cultured astrocytes. J. Biol. Chem. 266:9956-9960 (1991).
-
(1991)
J. Biol. Chem.
, vol.266
, pp. 9956-9960
-
-
Oka, S.1
Arita, H.2
-
16
-
-
0020051129
-
Delayed neuronal death in the gerbil hippocampus following ischemia
-
Kirino, T. Delayed neuronal death in the gerbil hippocampus following ischemia. Brain. Res. 239:57-69 (1982).
-
(1982)
Brain. Res.
, vol.239
, pp. 57-69
-
-
Kirino, T.1
-
17
-
-
0021912473
-
Interleukin-1 stimulation of astroglial proliferation after brain injury
-
Giulian, D., and L. B. Lachman. Interleukin-1 stimulation of astroglial proliferation after brain injury. Science (Washington, D. C.) 228:497-499 (1985).
-
(1985)
Science (Washington, D. C.)
, vol.228
, pp. 497-499
-
-
Giulian, D.1
Lachman, L.B.2
-
18
-
-
0027443904
-
Cytokines down-regulate expression of major cytochrome P450 enzymes in adult human hepatocytes in primary culture
-
Abdel-Razzak, Z., P. Loyer, A. Fautrel, J.-C. Gautier, L. Corcos, B. Turlin, P. Beaune, and A. Guillouzo. Cytokines down-regulate expression of major cytochrome P450 enzymes in adult human hepatocytes in primary culture. Mol. Pharmacol. 44:707-715 (1993).
-
(1993)
Mol. Pharmacol.
, vol.44
, pp. 707-715
-
-
Abdel-Razzak, Z.1
Loyer, P.2
Fautrel, A.3
Gautier, J.-C.4
Corcos, L.5
Turlin, B.6
Beaune, P.7
Guillouzo, A.8
-
19
-
-
0028013446
-
Regulation of cytochrome P4501A and cytochrome P4502E induction in the rat during the production of interferon α/β
-
Cribb, A. E., E. Delaporte, S. G. Kim, R. F, Novak, and K. W. Renton. Regulation of cytochrome P4501A and cytochrome P4502E induction in the rat during the production of interferon α/β. J. Pharmacol. Exp. Ther. 268:487-494 (1994).
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.268
, pp. 487-494
-
-
Cribb, A.E.1
Delaporte, E.2
Kim, S.G.3
Novak, R.F.4
Renton, K.W.5
-
20
-
-
0026781930
-
Interleukin-1β suppresses the induction of P450 1A1 and P450 1A2 mRNA in isolated hepatocytes
-
Barker, C. W., J. B. Fagan, and D. S. Pasco. Interleukin-1β suppresses the induction of P450 1A1 and P450 1A2 mRNA in isolated hepatocytes. J. Biol. Chem. 267:8050-8055 (1992).
-
(1992)
J. Biol. Chem.
, vol.267
, pp. 8050-8055
-
-
Barker, C.W.1
Fagan, J.B.2
Pasco, D.S.3
-
21
-
-
0029036153
-
Suppression of the constitutive expression of cytochrome P450 2C11 by cytokines and interferons in primary cultures of rat hepatocytes: Comparison with induction of acute-phase genes and demonstration that CYP2C11 promoter sequences are involved in the suppressive response to interleukins 1 and 6
-
Chen, J. Q., A. Ström, J.-Å. Gustafsson, and E. T. Morgan. Suppression of the constitutive expression of cytochrome P450 2C11 by cytokines and interferons in primary cultures of rat hepatocytes: comparison with induction of acute-phase genes and demonstration that CYP2C11 promoter sequences are involved in the suppressive response to interleukins 1 and 6. mol. Pharmacol. 47:940-947 (1995).
-
(1995)
Mol. Pharmacol.
, vol.47
, pp. 940-947
-
-
Chen, J.Q.1
Ström, A.2
Gustafsson, J.-Å.3
Morgan, E.T.4
-
22
-
-
0023931847
-
Astroglia from defined brain regions as studied with primary cultures
-
Hansson, E. Astroglia from defined brain regions as studied with primary cultures. Prog. Neurobiol. 30:369-397 (1988).
-
(1988)
Prog. Neurobiol.
, vol.30
, pp. 369-397
-
-
Hansson, E.1
-
23
-
-
0023900010
-
Ethanol-, fasting- and acetone inducible cytochromes P450 in rat liver: Regulation and characteristics of enzymes belonging to the 2B and 2E gene subfamilies
-
Johansson, I., G. Ekström, B. Scholte, D. Puzycki, H. Jörnvall, and M. Ingelman-Sundberg M. Ethanol-, fasting- and acetone inducible cytochromes P450 in rat liver: regulation and characteristics of enzymes belonging to the 2B and 2E gene subfamilies. Biochemistry 27:1925-1934 (1988).
-
(1988)
Biochemistry
, vol.27
, pp. 1925-1934
-
-
Johansson, I.1
Ekström, G.2
Scholte, B.3
Puzycki, D.4
Jörnvall, H.5
Ingelman-Sundberg M., M.6
-
24
-
-
0026094214
-
Neuroprotective activity of chlormethiazole following transient forebrain ischemia in the gerbil
-
Cross, A. J., J. A. Jones, H. A. Baldwin, and A. R. Green. Neuroprotective activity of chlormethiazole following transient forebrain ischemia in the gerbil. Br. J. Pharmacol. 104:406-411 (1991).
-
(1991)
Br. J. Pharmacol.
, vol.104
, pp. 406-411
-
-
Cross, A.J.1
Jones, J.A.2
Baldwin, H.A.3
Green, A.R.4
-
25
-
-
0028275367
-
Attenuation by chlormethiazole administration of the rise in extracellular amino acids following focal ischemia in the cerebral cortex of the rat
-
Baldwin, H. A., J. L. Williams, M. Snares, T. Ferreira, A. J. Cross, and A. R. Green. Attenuation by chlormethiazole administration of the rise in extracellular amino acids following focal ischemia in the cerebral cortex of the rat. Br. J. Pharmacol. 112:188-194 (1994).
-
(1994)
Br. J. Pharmacol.
, vol.112
, pp. 188-194
-
-
Baldwin, H.A.1
Williams, J.L.2
Snares, M.3
Ferreira, T.4
Cross, A.J.5
Green, A.R.6
-
26
-
-
0022512307
-
Induction of different isozymes of cytochrome P450 and of microsomal epoxide hydrolase in rat liver by 2-acetylamino-fluorene and structurally related compounds
-
Åström, A., W. Birberg, A. Pilotti, and J. W. DePierre. Induction of different isozymes of cytochrome P450 and of microsomal epoxide hydrolase in rat liver by 2-acetylamino-fluorene and structurally related compounds. Eur. J. Biochem. 154:125-34 (1986)
-
(1986)
Eur. J. Biochem.
, vol.154
, pp. 125-134
-
-
Åström, A.1
Birberg, W.2
Pilotti, A.3
DePierre, J.W.4
-
27
-
-
0023277545
-
Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction
-
Chomczynski, P. and N. Sacchi. Single-step method of RNA isolation by acid guanidinium thiocyanate-phenol-chloroform extraction. Analytical Biochemistry 162:156-159 (1987).
-
(1987)
Analytical Biochemistry
, vol.162
, pp. 156-159
-
-
Chomczynski, P.1
Sacchi, N.2
-
28
-
-
0025115739
-
Quantitative analysis of MDR1 gene expression in human tumours by polymerase chain reaction
-
Noonan, K. E., C. Beck, T. A. Holzmayer, J. E. Chin, J. S. Wunder, I. L. Andrulis, A. F. Gazdar, C. L. Willman, B. Griffith, D. D. Von Hoff, and I. B. Roninson. Quantitative analysis of MDR1 gene expression in human tumours by polymerase chain reaction. Proc. Natl. Acad. Sci. USA 87: 7160-7164 (1990).
-
(1990)
Proc. Natl. Acad. Sci. USA
, vol.87
, pp. 7160-7164
-
-
Noonan, K.E.1
Beck, C.2
Holzmayer, T.A.3
Chin, J.E.4
Wunder, J.S.5
Andrulis, I.L.6
Gazdar, A.F.7
Willman, C.L.8
Griffith, B.9
Von Hoff, D.D.10
Roninson, I.B.11
-
29
-
-
0022916435
-
Purification of a desmethylimipramine and debrisoquine hydroxylating cytochrome P450 from human liver
-
Birgersson, C., E. T. Morgan, H. Jörnvall, and C. von Bahr. Purification of a desmethylimipramine and debrisoquine hydroxylating cytochrome P450 from human liver. Biochem. Pharmacol. 35:3165-3166 (1986).
-
(1986)
Biochem. Pharmacol.
, vol.35
, pp. 3165-3166
-
-
Birgersson, C.1
Morgan, E.T.2
Jörnvall, H.3
Von Bahr, C.4
-
30
-
-
0027940270
-
Hypoxia/reoxygenation-mediated induction of astrocyte interleukin-6: A paracrine mechanism potentially enhancing neuron survival
-
Maeda, Y., M. Matsumoto, O. Hori, K. Kuwabara, S. Ogawa, S. D. Yan, T. Ohtsuki, T. Kinoshita, T. Kamada, and D. R. Stern. Hypoxia/reoxygenation-mediated induction of astrocyte interleukin-6: a paracrine mechanism potentially enhancing neuron survival. J. Exp. Med. 180:2297-2308 (1994).
-
(1994)
J. Exp. Med.
, vol.180
, pp. 2297-2308
-
-
Maeda, Y.1
Matsumoto, M.2
Hori, O.3
Kuwabara, K.4
Ogawa, S.5
Yan, S.D.6
Ohtsuki, T.7
Kinoshita, T.8
Kamada, T.9
Stern, D.R.10
-
31
-
-
0028918999
-
Selectivity of cytochrome P450 2E1 in chlorzoxazone 6-hydroxylation
-
Yamazaki, H., Z. Guo, and F. P. Guengerich. Selectivity of cytochrome P450 2E1 in chlorzoxazone 6-hydroxylation. Drug Metab. Dispos. 23:438-440 (1995).
-
(1995)
Drug Metab. Dispos.
, vol.23
, pp. 438-440
-
-
Yamazaki, H.1
Guo, Z.2
Guengerich, F.P.3
-
32
-
-
0027438967
-
Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazone
-
Carriere, V., T. Goasduff, D. Ratanasavanh, F. Morel, J. C. Gautier, A. Guillouzo, P. Beaune, and F. Berthou. Both cytochromes P450 2E1 and 1A1 are involved in the metabolism of chlorzoxazone. Chem. Res. Toxicol. 6:852-857 (1993)
-
(1993)
Chem. Res. Toxicol.
, vol.6
, pp. 852-857
-
-
Carriere, V.1
Goasduff, T.2
Ratanasavanh, D.3
Morel, F.4
Gautier, J.C.5
Guillouzo, A.6
Beaune, P.7
Berthou, F.8
-
33
-
-
0028997743
-
Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1
-
Ono, S., T. Hatanaka, H. Hotta, M. Tsutsui, T. Satoh, and F. J. Gonzalez. Chlorzoxazone is metabolized by human CYP1A2 as well as by human CYP2E1. Pharmacogenetics 5:143-150 (1995).
-
(1995)
Pharmacogenetics
, vol.5
, pp. 143-150
-
-
Ono, S.1
Hatanaka, T.2
Hotta, H.3
Tsutsui, M.4
Satoh, T.5
Gonzalez, F.J.6
-
34
-
-
0028233907
-
Chlormethiazole as an efficient inhibitor of cytochrome P450 2E1 expression in rat liver
-
Hu, Y., V. Mishin, I. Johansson, C. von Bahr, A. J. Cross, M. J. J. Ronis, T. M. Badger, and M. Ingelman-Sundberg. Chlormethiazole as an efficient inhibitor of cytochrome P450 2E1 expression in rat liver. J. Pharmacol. Exp. Ther. 269:1286-1291 (1994).
-
(1994)
J. Pharmacol. Exp. Ther.
, vol.269
, pp. 1286-1291
-
-
Hu, Y.1
Mishin, V.2
Johansson, I.3
Von Bahr, C.4
Cross, A.J.5
Ronis, M.J.J.6
Badger, T.M.7
Ingelman-Sundberg, M.8
-
35
-
-
0028790293
-
Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes
-
Chen, J. Q., M. Nikolovakarakashian, A. H. Merrill, and E. T. Morgan. Regulation of cytochrome P450 2C11 (CYP2C11) gene expression by interleukin-1, sphingomyelin hydrolysis, and ceramides in rat hepatocytes. J. Biol. Chem. 270:25233-25238 (1995).
-
(1995)
J. Biol. Chem.
, vol.270
, pp. 25233-25238
-
-
Chen, J.Q.1
Nikolovakarakashian, M.2
Merrill, A.H.3
Morgan, E.T.4
-
36
-
-
0028922570
-
Effect of carrageenan-induced granuloma on hepatic cytochrome P450 isozymes in rats
-
Muntane, J., V. Longo, M. T. Mitjarila, P. G. Gervasi, and M. Ingelman-Sundberg. Effect of carrageenan-induced granuloma on hepatic cytochrome P450 isozymes in rats. Inflammation 19:143-56 (1995).
-
(1995)
Inflammation
, vol.19
, pp. 143-156
-
-
Muntane, J.1
Longo, V.2
Mitjarila, M.T.3
Gervasi, P.G.4
Ingelman-Sundberg, M.5
-
37
-
-
0027660930
-
Involvement of interleukin-1 and lipocortin-1 in ischemic brain damage
-
Rothwell, N. J., and J. K. Reiten. Involvement of interleukin-1 and lipocortin-1 in ischemic brain damage. Cerebrovasc. Brain Metab. Rev. 5:178-198 (1993).
-
(1993)
Cerebrovasc. Brain Metab. Rev.
, vol.5
, pp. 178-198
-
-
Rothwell, N.J.1
Reiten, J.K.2
-
38
-
-
0023772364
-
Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization
-
Giulian, D., J. Woodward, D. Young, J. F. Krebs, and L. B. Lachman. Interleukin-1 injected into mammalian brain stimulates astrogliosis and neovascularization. J. Neurosci. 8:2485-2490 (1988).
-
(1988)
J. Neurosci.
, vol.8
, pp. 2485-2490
-
-
Giulian, D.1
Woodward, J.2
Young, D.3
Krebs, J.F.4
Lachman, L.B.5
-
39
-
-
0029294575
-
Inducible NOS gene expression in brain following cerebral ischemia
-
Iadecola, C., F. Zhang, S. Xu, R. Casey, and M. E. Ross. Inducible NOS gene expression in brain following cerebral ischemia. J. Cereb. Bloodflow. Metab. 15:378-384 (1995).
-
(1995)
J. Cereb. Bloodflow. Metab.
, vol.15
, pp. 378-384
-
-
Iadecola, C.1
Zhang, F.2
Xu, S.3
Casey, R.4
Ross, M.E.5
-
40
-
-
0027205136
-
Metablism of arachidonic acid to epoxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and prostaglandins in cultured rat hippocampal astrocytes
-
Amruthesh, S. C., M. F. Boerschel, J. S. McKinney, K. A. Willoughby, and E. F. Ellis. Metablism of arachidonic acid to epoxyeicosatrienoic acids, hydroxyeicosatetraenoic acids, and prostaglandins in cultured rat hippocampal astrocytes. J. Neurochem. 61:150-159 (1993).
-
(1993)
J. Neurochem.
, vol.61
, pp. 150-159
-
-
Amruthesh, S.C.1
Boerschel, M.F.2
McKinney, J.S.3
Willoughby, K.A.4
Ellis, E.F.5
|