Expression of CD14 by hepatocytes: Upregulation by cytokines during endotoxemia

Infection and Immunity

Volumn 66, Issue 11, 1998, Pages 5089-5098

  Liu, Shubing ^a,c   Khemlani, Lajwanti S ^b   Shapiro, Richard A ^a   Johnson, Mark L ^a   Liu, Kaihong ^a   Geller, David A ^a   Watkins, Simon C ^a   Goyert, Sanna M ^b   Billiar, Timothy R ^a  

^a UNIVERSITY OF PITTSBURGH SCHOOL OF MEDICINE   (United States)

^b NORTH SHORE UNIVERSITY HOSPITAL   (United States)

^c UNIVERSITY OF PITTSBURGH MEDICAL CENTER   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CD14 ANTIGEN; MESSENGER RNA;

AMINO ACID SEQUENCE; ANIMAL CELL; ANTIGEN EXPRESSION; ARTICLE; CONTROLLED STUDY; ENDOTOXEMIA; GENE EXPRESSION; IN SITU HYBRIDIZATION; LIVER CELL; NONHUMAN; OPEN READING FRAME; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; RNA ANALYSIS; SEQUENCE HOMOLOGY;

EID: 0032423246     PISSN: 00199567     EISSN: None     Source Type: Journal    
DOI: 10.1128/iai.66.11.5089-5098.1998     Document Type: Article

References (7)

1. Arditi, M., J. Zhou, M. Torres, D. L. Durden, M. Stins, and K. S. Kim. 1995. Lipopolysaccharide stimulates the tyrosine phosphorylation of mitogen-activated protein kinase p44, p42, and p41 in vascular endothelial cells in a soluble CD14-dependent manner. J. Immunol. 155:3994-4003.
2. Baumann, H., K. K. Morella, and G. H. W. Wong. 1993. TNFα, IL-1β, and hepatocyte growth factor cooperate in stimulating specific acute-phase plasma protein gene in rat hepatoma cells. J. Immunol. 151:4248-4255.
3. Bellezzo, J. M., R. S. Britton, B. R. Bacon, and E. S. Fox. 1996. LPS-mediated NF-kappa beta activation in rat Kupffer cells can be induced independently of CD14. Am. J. Physiol. 270:G956-G961.
4. Boggaram, V., and C. R. Mendelson. 1988. Transcriptional regulation of the gene coding the major surfactant protein (SPA) in rabbit fetal lung. J. Biol. Chem. 263:19060-19065.
5. Burgmann, H., S. Winkler, G. J. Locker, E. Presterl, K. Laczika, T. Staudinger, S. Knapp, F. Thalhammer, C. Wenisch, K. Zedwitz-Liebenstein, M. Frass, and W. Graninger. 1996. Increased serum concentration of soluble CD14 is a prognostic marker in gram-positive sepsis. Clin. Immunol. Immunopathol. 80:307-310.
6. Caput, D., B. Beutler, K. Hartog, R. Thayer, S. Brown-Shimer, and A. Cerami. 1986. Identification of a common nucleotide sequence in the 3′-untranslated region of mRNA molecules specifying inflammatory mediators. Proc. Natl. Acad. Sci. USA 83:1670-1674.
7. Cybulsky, M. I., M. K. W. Chan, and H. Z. Movat. 1988. Acute inflammation and microthrombosis induced by endotoxin, interleukin-1, and tumor necrosis factor and their implication in gram-negative infection. Lab. Investig. 58:365-376.