Leukotriene B4 ω-side chain hydroxylation by CYP4F5 and CYP4F6

Archives of Biochemistry and Biophysics

Volumn 412, Issue 1, 2003, Pages 34-41

  Bylund, Johan ^a   Harder, Adam G ^a   Maier, Kristopher G ^a   Roman, Richard J ^a   Harder, David R ^a  

^a MEDICAL COLLEGE OF WISCONSIN   (United States)

Author keywords

18 Hydroxy LTB4; 19 Hydroxy LTB4; Cytochrome P450; Hydroxylase; Microsomes; Northern blot

Indexed keywords

18 HYDROXYLEUKOTRIENE B4; 19 HYDROXYLEUKOTRIENE B4; CYTOCHROME P450; CYTOCHROME P4F5; CYTOCHROME P4F6; LEUKOTRIENE B4; MESSENGER RNA; UNCLASSIFIED DRUG; COMPLEMENTARY DNA; CYP4F5 PROTEIN, RAT; CYP4F6 PROTEIN, RAT; RECOMBINANT PROTEIN;

ANIMAL TISSUE; ARTICLE; BRAIN; CONTROLLED STUDY; HYDROXYLATION; INFLAMMATION; KIDNEY; LIPID METABOLISM; LUNG; MALE; MICROSOME; NONHUMAN; ORGAN; PRIORITY JOURNAL; PROTEIN EXPRESSION; RAT; TESTIS; YEAST; ANIMAL; CHEMISTRY; DOSE RESPONSE; KINETICS; LIQUID CHROMATOGRAPHY; MASS FRAGMENTOGRAPHY; METABOLISM; MOLECULAR CLONING; NORTHERN BLOTTING; PHYSIOLOGY; PROTEIN BINDING; TIME;

ANIMALS; BLOTTING, NORTHERN; CHROMATOGRAPHY, LIQUID; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; DNA, COMPLEMENTARY; DOSE-RESPONSE RELATIONSHIP, DRUG; GAS CHROMATOGRAPHY-MASS SPECTROMETRY; KIDNEY; KINETICS; LEUKOTRIENE B4; MALE; MICROSOMES; PROTEIN BINDING; RATS; RECOMBINANT PROTEINS; RNA, MESSENGER; TIME FACTORS;

EID: 0037376494     PISSN: 00039861     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0003-9861(03)00030-4     Document Type: Article

References (26)

1. Samuelsson B., Dahlen S.E., Lindgren J.A., Rouzer C.A., Serhan C.N. Science. 237:1987;1171-1176.
2. Toda A., Yokomizo T., Shimizu T. Prostaglandins Other Lipid Mediat. 68-69:2002;575-585.
3. Yokomizo T., Izumi T., Shimizu T. Arch. Biochem. Biophys. 385:2001;231-241.
4. Kikuta Y., Kusunose E., Kusunose M. Prostaglandins Other Lipid Mediat. 68-69:2002;345-362.
5. Wheelan P., Hankin J.A., Bilir B., Guenette D., Murphy R.C. J. Pharmacol. Exp. Ther. 288:1999;326-334.
6. Kikuta Y., Kasyu H., Kusunose E., Kusunose M. Arch. Biochem. Biophys. 383:2000;225-232.
7. Powell W.S. J. Biol. Chem. 259:1984;3082-3089.
8. Kikuta Y., Kusunose E., Endo K., Yamamoto S., Sogawa K., Fujii-Kuriyama Y., Kusunose M. J. Biol. Chem. 268:1993;9376-9380.
9. Wang S., Gustafson E., Pang L., Qiao X., Behan J., Maguire M., Bayne M., Laz T. J. Biol. Chem. 275:2000;40686-40694.
10. Clancy R.M., Dahinden C.A., Hugli T.E. Proc. Natl. Acad. Sci. USA. 81:1984;5729-5733.
11. Baumert T., Huber M., Mayer D., Keppler D. Eur. J. Biochem. 182:1989;223-229.
12. Kikuta Y., Kusunose E., Kondo T., Yamamoto S., Kinoshita H., Kusunose M. FEBS Lett. 348:1994;70-74.
13. Christmas P., Jones J.P., Patten C.J., Rock D.A., Zheng Y., Cheng S.M., Weber B.M., Carlesso N., Scadden D.T., Rettie A.E., Soberman R.J. J. Biol. Chem. 276:2001;38166-38172.
14. Hankin J.A., Clay C.E., Murphy R.C. J. Pharmacol. Exp. Ther. 285:1998;155-161.
15. Chen L., Hardwick J.P. Arch. Biochem. Biophys. 300:1993;18-23.
16. Kawashima H., Strobel H.W. Biochem. Biophys. Res. Commun. 217:1995;1137-1144.
17. Powell W.S., Gravelle F. J. Biol. Chem. 265:1990;9131-9139.
18. Kawashima H., Kusunose E., Thompson C.M., Strobel H.W. Arch. Biochem. Biophys. 347:1997;148-154.
19. Kalsotra A., Anakk S., Boehme C.L., Strobel H.W. Drug Metab. Dispos. 30:2002;1022-1028.
20. Kikuta Y., Kusunose E., Ito M., Kusunose M. Arch. Biochem. Biophys. 369:1999;193-196.
21. Truan G., Cullin C., Reisdorf P., Urban P., Pompon D. Gene. 125:1993;49-55.
22. Bylund J., Hidestrand M., Ingelman-Sundberg M., Oliw E.H. J. Biol. Chem. 275:2000;21844-21849.
23. Alkayed N.J., Narayanan J., Gebremedhin D., Medhora M., Roman R.J., Harder D.R. Stroke. 27:1996;971-979.
24. Bylund J., Ericsson J., Oliw E.H. Anal. Biochem. 265:1998;55-68.
25. Dahinden C.A., Clancy R.M., Hugli T.E. J. Immunol. 133:1984;1477-1482.
26. Lasker J.M., Chen W.B., Wolf I., Bloswick B.P., Wilson P.D., Powell P.K. J. Biol. Chem. 275:2000;4118-4126.