Interindividual differences in hepatic expression of CYP3A4: Relationship to genetic polymorphism in the 5'-upstream regulatory region

Biochemical and Biophysical Research Communications

Volumn 259, Issue 1, 1999, Pages 201-205

  Westlind, Anna ^a   Löfberg, Lena ^b   Tindberg, Niclas ^a   Andersson, Tommy B ^b   Ingelman Sundberg, Magnus ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

^b ASTRAZENECA R AND D   (Sweden)

Author keywords

Leukaemia; Nifedipine; Pregnenolone X receptor; Prostate cancer; Testosterone hydroxylase

Indexed keywords

CYTOCHROME P450 3A4; CYTOCHROME P450 ISOENZYME; LIVER ENZYME; NIFEDIPINE; NUCLEAR PROTEIN; OXYGENASE; UNCLASSIFIED DRUG;

ADULT; AGED; ALLELE; ARTICLE; BINDING AFFINITY; CLINICAL ARTICLE; CONTROLLED STUDY; DNA DETERMINATION; DRUG METABOLISM; ENZYME ACTIVITY; ENZYME SPECIFICITY; FEMALE; GENE MUTATION; GENETIC POLYMORPHISM; HEREDITY; HUMAN; HUMAN CELL; LIVER MICROSOME; MALE; PRIORITY JOURNAL; PROMOTER REGION; PROTEIN BINDING; PROTEIN EXPRESSION; REGULATOR GENE; SEQUENCE HOMOLOGY; TESTOSTERONE METABOLISM;

EID: 0345643389     PISSN: 0006291X     EISSN: None     Source Type: Journal    
DOI: 10.1006/bbrc.1999.0752     Document Type: Article

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