Regulation of CYP3A gene transcription by the pregnane X receptor

Annual Review of Pharmacology and Toxicology

Volumn 42, Issue , 2002, Pages 1-23

  Goodwin, Bryan ^a   Redinbo, Matthew R ^a   Kliewer, Steven A ^a  

^a GLAXOSMITHKLINE   (United States)

Author keywords

Bile acids; CYP3A; Drug interactions; Nuclear receptor; Xenobiotic metabolism

Indexed keywords

16ALPHA CYANOPREGNENOLONE; BILE ACID; CELL NUCLEUS RECEPTOR; CYTOCHROME P450 3A; DEXAMETHASONE; HYPERFORIN; LITHOCHOLIC ACID; MIFEPRISTONE; PREGNANE DERIVATIVE; PREGNANE X RECEPTOR; PREGNANE X RECEPTOR AGONIST; PREGNANEDIONE; RIFAMPICIN; SR 12813; STEROID; UNCLASSIFIED DRUG; UNSPECIFIC MONOOXYGENASE; XENOBIOTIC AGENT;

DRUG RECEPTOR BINDING; HUMAN; INTRAHEPATIC CHOLESTASIS; LIPOPHILICITY; LIVER DISEASE; PRESCRIPTION; PRIORITY JOURNAL; RECEPTOR BINDING; REGULATOR GENE; REVIEW; STRUCTURE ANALYSIS; TRANSCRIPTION REGULATION;

ANIMALS; ARYL HYDROCARBON HYDROXYLASES; BILE ACIDS AND SALTS; BINDING SITES; CATALYSIS; CYTOCHROME P-450 CYP3A; CYTOCHROME P-450 ENZYME SYSTEM; GENE EXPRESSION REGULATION, ENZYMOLOGIC; HOMEOSTASIS; HUMANS; OXIDOREDUCTASES, N-DEMETHYLATING; RECEPTORS, CYTOPLASMIC AND NUCLEAR; RECEPTORS, STEROID; TRANSCRIPTION, GENETIC; XENOBIOTICS;

STAPHYLOCOCCUS PHAGE 3A;

EID: 0036171965     PISSN: 03621642     EISSN: None     Source Type: Book Series    
DOI: 10.1146/annurev.pharmtox.42.111901.111051     Document Type: Review

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