Polymorphic human cytochrome P450 enzymes: An opportunity for individualized drug treatment

Trends in Pharmacological Sciences

Volumn 20, Issue 8, 1999, Pages 342-349

  Ingelman Sundberg, Magnus ^a   Oscarson, Mikael ^a   McLellan, Roman A ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

[No Author keywords available]

Indexed keywords

AMOXICILLIN; ANALGESIC AGENT; ANTIARRHYTHMIC AGENT; ANTICOAGULANT AGENT; ANTIMALARIAL AGENT; CODEINE; CYCLOGUANIL; CYTOCHROME P450; CYTOCHROME P450 ISOENZYME; DEXFENFLURAMINE; HALOPERIDOL; LOSARTAN; MEPHENYTOIN; MORPHINE; NEUROLEPTIC AGENT; NICOTINE; NONSTEROID ANTIINFLAMMATORY AGENT; NORTRIPTYLINE; OMEPRAZOLE; OXYCODONE; PERHEXILINE; PERPHENAZINE; PHENYTOIN; PRODRUG; PROGUANIL; SEROTONIN UPTAKE INHIBITOR; TOLBUTAMIDE; TRAMADOL; UNINDEXED DRUG; WARFARIN;

ALLELE; DRUG METABOLISM; ENZYME LOCALIZATION; GENE DUPLICATION; GENE MUTATION; GENETIC DISORDER; GENETIC POLYMORPHISM; HUMAN; LIVER MICROSOME METABOLISM; PHENOTYPE; PRIORITY JOURNAL; PROTEIN POLYMORPHISM; REVIEW;

ALLELES; ANTI-INFLAMMATORY AGENTS, NON-STEROIDAL; CYTOCHROME P-450 CYP2D6; CYTOCHROME P-450 ENZYME SYSTEM; EVOLUTION, MOLECULAR; HUMANS; POLYMORPHISM, GENETIC; SEROTONIN UPTAKE INHIBITORS;

EID: 0032793249     PISSN: 01656147     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0165-6147(99)01363-2     Document Type: Review

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