Human drug metabolising cytochrome P450 enzymes: Properties and polymorphisms

Naunyn-Schmiedeberg's Archives of Pharmacology

Volumn 369, Issue 1, 2004, Pages 89-104

  Ingelman Sundberg, Magnus ^a  

^a KAROLINSKA INSTITUTE   (Sweden)

Author keywords

Adverse drug reactions; Cancer drugs; Genetic polymorphism; Haplotypes; Poor metabolizers; Ultrarapid metabolizers

Indexed keywords

AMFEBUTAMONE; ANTINEOPLASTIC AGENT; ARTEMISIN; BENZIMIDAZOLE DERIVATIVE; BUFURALOL; CLOMETHIAZOLE; CYCLOSPORIN; CYCLOSPORIN A; CYTOCHROME P450 1B1; CYTOCHROME P450 2B6; CYTOCHROME P450 2E1; CYTOCHROME P450 3A; DEBRISOQUINE; DEXTROMETHORPHAN; ERYTHROMYCIN; FLUCONAZOLE; ITRACONAZOLE; KETAMINE; KETOCONAZOLE; LOSARTAN; MEPHENYTOIN; MIDAZOLAM; NORMEPHENYTOIN; OMEPRAZOLE; SELEGILINE; THIOTEPA; TOLBUTAMIDE; TROLEANDOMYCIN; UNINDEXED DRUG; WARFARIN;

CATALYSIS; CATALYST; DETOXIFICATION; DRUG METABOLISM; ENZYME POLYMORPHISM; GENETIC CODE; HUMAN; HYDROXYLATION; MOLECULAR RECOGNITION; NONHUMAN; PHARMACOGENETICS; PROTEIN EXPRESSION; PROTEIN INTERACTION; REVIEW; SIDE EFFECT;

CYTOCHROME P-450 ENZYME SYSTEM; HUMANS; METABOLIC DETOXICATION, DRUG; POLYMORPHISM, GENETIC; SUBSTRATE SPECIFICITY; TERMINOLOGY; XENOBIOTICS;

EID: 0742321734     PISSN: 00281298     EISSN: None     Source Type: Journal    
DOI: 10.1007/s00210-003-0819-z     Document Type: Review

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