Extensive genetic polymorphism in the human CYP2B6 gene with impact on expression and function in human liver

Pharmacogenetics

Volumn 11, Issue 5, 2001, Pages 399-415

  Lang, T ^a   Klein, K ^a   Fischer, J ^a   Nussler A K ^a   Neuhaus, P ^a   Hofmann, U ^a   Eichelbaum, M ^a   Schwab, M ^a   Zanger, U M ^a  

^a DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

Author keywords

CYP2B6; Genetic polymorphism; Pharmacogenetics

Indexed keywords

CYTOCHROME P450; CYTOCHROME P450 2B6; CYTOCHROME P450 2B7; DNA; UNCLASSIFIED DRUG;

ALLELE; AMINO ACID SUBSTITUTION; ARTICLE; CHROMOSOME 19; CONTROLLED STUDY; DRUG METABOLISM; ENZYME ACTIVITY; EXON; GENE EXPRESSION; GENE FREQUENCY; GENE MUTATION; GENE SEQUENCE; GENETIC ANALYSIS; GENETIC POLYMORPHISM; GENETIC VARIABILITY; HAPLOTYPE; HUMAN; HUMAN CELL; INTRON; LIVER FUNCTION; NORMAL HUMAN; NUCLEOTIDE SEQUENCE; POLYMERASE CHAIN REACTION; PRIORITY JOURNAL; PROTEIN EXPRESSION; SCREENING; SILENT GENE;

ARYL HYDROCARBON HYDROXYLASES; BASE SEQUENCE; CLONING, MOLECULAR; CYTOCHROME P-450 ENZYME SYSTEM; DNA PRIMERS; DNA, COMPLEMENTARY; EXONS; HUMANS; INTRONS; OXIDOREDUCTASES, N-DEMETHYLATING; POLYMERASE CHAIN REACTION; POLYMORPHISM, GENETIC;

EID: 0034948077     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200107000-00004     Document Type: Article

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