메뉴 건너뛰기




Volumn 41, Issue 2, 2000, Pages 163-181

Cytochrome P450 and arachidonic acid bioactivation: Molecular and functional properties of the arachidonate monooxygenase

Author keywords

Arachidonic acid; Arachidonic acid epoxygenase; Arachidonic acid monooxygenase; Cytochrome P450; EDHF; EET; Eicosanoids; Fatty acid hydroxylase; HETE; Hyperpolarizing factor; Hypertension; Salt sensitivity

Indexed keywords

ARACHIDONIC ACID; CYTOCHROME P450; ENDOTHELIUM DERIVED HYPERPOLARIZING FACTOR; FATTY ACID; HYDROXYICOSATETRAENOIC ACID; ICOSANOID; ICOSATRIENOIC ACID; ION CHANNEL; OXYGENASE;

EID: 0033993749     PISSN: 00222275     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Review
Times cited : (483)

References (216)
  • 1
    • 0026761179 scopus 로고
    • Prostanoid biosynthesis and mechanism of action
    • and references therein
    • Smith, W. L. 1992. Prostanoid biosynthesis and mechanism of action. Am. J. Physiol. 263: F181-F191/ and references therein.
    • (1992) Am. J. Physiol. , vol.263
    • Smith, W.L.1
  • 2
    • 0030479496 scopus 로고    scopus 로고
    • Prostaglandin endoperoxide H synthases (Cyclooxygenases) -1 and -2
    • and references therein
    • Smith, W. L., M. R. Garavito, and D. L. DeWitt. 1996. Prostaglandin Endoperoxide H Synthases (Cyclooxygenases) -1 and -2. J. Biol. Chem. 271: 33157-33160 and references therein.
    • (1996) J. Biol. Chem. , vol.271 , pp. 33157-33160
    • Smith, W.L.1    Garavito, M.R.2    DeWitt, D.L.3
  • 5
    • 0025780578 scopus 로고
    • Cytochrome P-450 metabolism of AA
    • and references therein
    • McGiff, J. C. 1991. Cytochrome P-450 metabolism of AA. Annu. Rev. Pharmacol. Toxicol. 31: 339-369 and references therein.
    • (1991) Annu. Rev. Pharmacol. Toxicol. , vol.31 , pp. 339-369
    • McGiff, J.C.1
  • 6
    • 0028335991 scopus 로고
    • Oxygenation of polyunsaturated fatty acids by cytochrome P450 monooxygenases
    • and references therein
    • Oliw, E. H. 1994. Oxygenation of polyunsaturated fatty acids by cytochrome P450 monooxygenases. Prog. Lipid Res. 33: 329-354 and references therein.
    • (1994) Prog. Lipid Res. , vol.33 , pp. 329-354
    • Oliw, E.H.1
  • 7
    • 0028904786 scopus 로고
    • Role of cytochrome P450 enzymes and metabolites of AA in the control of vascular tone
    • and references therein
    • Harder, D. R., W. B. Campbell, and R. J. Roman. 1995. Role of cytochrome P450 enzymes and metabolites of AA in the control of vascular tone. J. Vasc. Res. 32: 79-92 and references therein.
    • (1995) J. Vasc. Res. , vol.32 , pp. 79-92
    • Harder, D.R.1    Campbell, W.B.2    Roman, R.J.3
  • 8
    • 0029825327 scopus 로고    scopus 로고
    • Cytochrome P450, the AA cascade, and hypertension: New vistas for an old enzyme system
    • and references therein
    • Makita, K., J. R. Falck, and J. H. Capdevila. 1996. Cytochrome P450, the AA cascade, and hypertension: new vistas for an old enzyme system. FASEB J. 10: 1456-1463 and references therein.
    • (1996) FASEB J. , vol.10 , pp. 1456-1463
    • Makita, K.1    Falck, J.R.2    Capdevila, J.H.3
  • 9
    • 0030051377 scopus 로고    scopus 로고
    • Missing links: Cytochrome P450 arachidonate products
    • and references therein
    • McGiff, J. C., M. Steinberg, and J. Quilley 1996. Missing links: Cytochrome P450 arachidonate products. Trends Cardiovasc. Med. 6: 4-10 and references therein.
    • (1996) Trends Cardiovasc. Med. , vol.6 , pp. 4-10
    • McGiff, J.C.1    Steinberg, M.2    Quilley, J.3
  • 10
    • 0029756792 scopus 로고    scopus 로고
    • Cytochrome P450 expression and AA omega-hydroxylation in the kidney of spontaneously hypertensive rat
    • and references therein
    • Schwartzman, M. L., J. L. DaSilva, F. Lin, M. Nishimura, and N. G. Abraham. 1996. Cytochrome P450 expression and AA omega-hydroxylation in the kidney of spontaneously hypertensive rat. Nephron. 73: 652-663 and references therein.
    • (1996) Nephron. , vol.73 , pp. 652-663
    • Schwartzman, M.L.1    DaSilva, J.L.2    Lin, F.3    Nishimura, M.4    Abraham, N.G.5
  • 11
    • 0030889716 scopus 로고    scopus 로고
    • The role of cytochrome P450-dependent metabolites of AA in blood pressure regulation and renal function
    • and references therein
    • Rahman, M., J. T. Wright, and J. G. Douglas. 1997. The role of cytochrome P450-dependent metabolites of AA in blood pressure regulation and renal function. Am. J. Hypertension. 10: 356-365 and references therein.
    • (1997) Am. J. Hypertension , vol.10 , pp. 356-365
    • Rahman, M.1    Wright, J.T.2    Douglas, J.G.3
  • 12
    • 0031002404 scopus 로고    scopus 로고
    • Cytochrome P450 metabolites of AA as intracellular signaling molecules invascular tissue
    • and references therein
    • Harder, D. R., A. R. Lange, D. Gebremedhin, E. K. Birks, and R. J. Roman. 1997. Cytochrome P450 metabolites of AA as intracellular signaling molecules invascular tissue. J. Vasc. Res. 34: 237-243 and references therein.
    • (1997) J. Vasc. Res. , vol.34 , pp. 237-243
    • Harder, D.R.1    Lange, A.R.2    Gebremedhin, D.3    Birks, E.K.4    Roman, R.J.5
  • 14
    • 0000162235 scopus 로고
    • Hormonal regulation of liver cytochrome P450 enzymes
    • P. R. Ortiz de Montellano, editor. Plenum Press, New York
    • Waxman, D. J., and T. K. H. Chang. 1995. Hormonal regulation of liver cytochrome P450 enzymes. In Cytochrome P450: Structure, Mechanism, and Biochemistry (2nd edition). P. R. Ortiz de Montellano, editor. Plenum Press, New York. 391-418.
    • (1995) Cytochrome P450: Structure, Mechanism, and Biochemistry (2nd Edition) , pp. 391-418
    • Waxman, D.J.1    Chang, T.K.H.2
  • 17
    • 0014026978 scopus 로고
    • Prostaglandins in human seminal plasma. Prostaglandins and related factors
    • Hamberg, M., and B. Samuelsson. 1966. Prostaglandins in human seminal plasma. Prostaglandins and related factors. J. Biol. Chem. 241: 257-263.
    • (1966) J. Biol. Chem. , vol.241 , pp. 257-263
    • Hamberg, M.1    Samuelsson, B.2
  • 18
    • 0023883952 scopus 로고
    • Regioselective hydroxylation of prostaglandins by constitutive forms of cytochrome P-450 from rat liver: Formation of a novel metabolite by a female-specific P-450
    • Kupfer, D., I. Jansson, L. V. Favreau, A. D. Theoharides, and J. B. Schenkman. 1988. Regioselective hydroxylation of prostaglandins by constitutive forms of cytochrome P-450 from rat liver: formation of a novel metabolite by a female-specific P-450. Arch. Biochem. Biophys. 262: 186-195.
    • (1988) Arch. Biochem. Biophys. , vol.262 , pp. 186-195
    • Kupfer, D.1    Jansson, I.2    Favreau, L.V.3    Theoharides, A.D.4    Schenkman, J.B.5
  • 19
    • 0024473078 scopus 로고
    • Biosynthesis of 18(R)-hydroxyeicosatetraenoic acid from arachidonicacid by microsomes of monkey seminal vesicles
    • Oliw, E. H. 1989. Biosynthesis of 18(R)-hydroxyeicosatetraenoic acid from arachidonicacid by microsomes of monkey seminal vesicles. J. Biol. Chem. 264: 17845-17853.
    • (1989) J. Biol. Chem. , vol.264 , pp. 17845-17853
    • Oliw, E.H.1
  • 21
    • 0002544262 scopus 로고
    • Endogenous substrates of monooxygenases: Fatty acids and prostaglandins
    • J. B. Schenkman and D. Kupfer, editors. Pergamon Press, New York
    • Kupfer, D. 1982. Endogenous substrates of monooxygenases: fatty acids and prostaglandins. In Hepatic Cytochrome P-450 Monooxygenase System. J. B. Schenkman and D. Kupfer, editors. Pergamon Press, New York. 157-182.
    • (1982) Hepatic Cytochrome P-450 Monooxygenase System , pp. 157-182
    • Kupfer, D.1
  • 24
    • 0021340133 scopus 로고
    • 12S,20-Dihydroxyeicosatetraenoic acid: A new icosanoid synthesized by neutrophils from 12S-hydroxyeicosatetraenoic acid produced by thrombin- or collage-stimulated platelets
    • Marcus, A. J., L. B. Safier, H. L. Ullman, M. J. Brockman, N. Islam, T. D. Oglesby, and R. Gorman. 1984. 12S,20-Dihydroxyeicosatetraenoic acid: a new icosanoid synthesized by neutrophils from 12S-hydroxyeicosatetraenoic acid produced by thrombin- or collage-stimulated platelets. Proc. Natl. Acad. Sci. USA. 81: 903-907.
    • (1984) Proc. Natl. Acad. Sci. USA , vol.81 , pp. 903-907
    • Marcus, A.J.1    Safier, L.B.2    Ullman, H.L.3    Brockman, M.J.4    Islam, N.5    Oglesby, T.D.6    Gorman, R.7
  • 25
    • 0021289320 scopus 로고
    • 4 20-hydroxylase from polymorphonuclear leukocytes
    • 4 20-hydroxylase from polymorphonuclear leukocytes. J. Biol. Chem. 259: 3082-3089.
    • (1984) J. Biol. Chem. , vol.259 , pp. 3082-3089
    • Powell, W.S.1
  • 26
    • 0021327241 scopus 로고
    • ω-Hydroxylation of 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid in humanpolymorphonuclear leukocytes
    • Wong, P. Y. K., P. Westlund, M. Hamberg, E. Granstrom, P. W. H. Chao, and B. Samuelsson. 1984. ω-Hydroxylation of 12-L-hydroxy-5,8,10,14-eicosatetraenoic acid in humanpolymorphonuclear leukocytes. J. Biol. Chem. 259: 2683-2686.
    • (1984) J. Biol. Chem. , vol.259 , pp. 2683-2686
    • Wong, P.Y.K.1    Westlund, P.2    Hamberg, M.3    Granstrom, E.4    Chao, P.W.H.5    Samuelsson, B.6
  • 29
    • 0014599125 scopus 로고
    • The effects of unsaturated fatty acids on hepatic microsomal drug metabolism and cytochrome P-450
    • DiAgustine, R. P., and J. R. Fouts. 1969. The effects of unsaturated fatty acids on hepatic microsomal drug metabolism and cytochrome P-450. Biochem. J. 115: 547-554.
    • (1969) Biochem. J. , vol.115 , pp. 547-554
    • DiAgustine, R.P.1    Fouts, J.R.2
  • 31
    • 0017103068 scopus 로고
    • Platelet cytochrome P-450: A possible role inarachidonate-induced aggregation
    • Cinti, D. L., and M. B. Feinstein. 1976. Platelet cytochrome P-450: A possible role inarachidonate-induced aggregation. Biochem. Biophys. Res. Commun. 73: 171-179.
    • (1976) Biochem. Biophys. Res. Commun. , vol.73 , pp. 171-179
    • Cinti, D.L.1    Feinstein, M.B.2
  • 34
    • 0019770983 scopus 로고
    • Oxygenation of AA by hepatic microsomes of the rabbit. Mechanism of biosynthesis of two vicinal diols
    • Oliw, E. H., and J. A. Oates. 1981. Oxygenation of AA by hepatic microsomes of the rabbit. Mechanism of biosynthesis of two vicinal diols. Biochim. Biophys. Acta. 666: 327-340.
    • (1981) Biochim. Biophys. Acta. , vol.666 , pp. 327-340
    • Oliw, E.H.1    Oates, J.A.2
  • 35
    • 0019853320 scopus 로고
    • Metabolism of AA through NADPH-dependent oxygenase of renal cortex
    • Morrison, A. R., and N. Pascoe. 1981. Metabolism of AA through NADPH-dependent oxygenase of renal cortex. Proc. Natl. Acad. Sci. USA. 78: 7375-7378.
    • (1981) Proc. Natl. Acad. Sci. USA , vol.78 , pp. 7375-7378
    • Morrison, A.R.1    Pascoe, N.2
  • 36
    • 0020510129 scopus 로고
    • Novel hypothalamic arachidonate products stimulate somatostatin release from themedian eminence
    • Capdevila, J. H., N. Chacos, J. R. Falck, S. Manna, A. Negro-Vilar, and S. R. Ojeda. 1983. Novel hypothalamic arachidonate products stimulate somatostatin release from themedian eminence. Endocrinology, 113: 421-423.
    • (1983) Endocrinology , vol.113 , pp. 421-423
    • Capdevila, J.H.1    Chacos, N.2    Falck, J.R.3    Manna, S.4    Negro-Vilar, A.5    Ojeda, S.R.6
  • 37
    • 0001646348 scopus 로고
    • Effects of epoxyeicosatrienoic acids on ion transport in the rabbit cortical collecting tubule
    • P. Braquet, J. C. Frolich, S. Nicosia, and R. Garay, editors. Raven Press, New York
    • Jacobson, H. R., S. Corona, J. H. Capdevila, N. Chacos, S. Manna, A. Womack, and J. R. Falck. 1984. Effects of epoxyeicosatrienoic acids on ion transport in the rabbit cortical collecting tubule. In Prostaglandins and Membrane Ion Transport. P. Braquet, J. C. Frolich, S. Nicosia, and R. Garay, editors. Raven Press, New York. 311.
    • (1984) Prostaglandins and Membrane Ion Transport , pp. 311
    • Jacobson, H.R.1    Corona, S.2    Capdevila, J.H.3    Chacos, N.4    Manna, S.5    Womack, A.6    Falck, J.R.7
  • 38
    • 0021236229 scopus 로고
    • Arachidonic acid epoxidation: Epoxyeicosatrienoic acids are endogenous constituents of rat liver
    • Capdevila, J. H., B. Pramanik, J. L. Napoli, S. Manna, and J. R. Falck. 1984. Arachidonic acid epoxidation: epoxyeicosatrienoic acids are endogenous constituents of rat liver. Arch. Biochem. Biophys. 231: 511-517.
    • (1984) Arch. Biochem. Biophys. , vol.231 , pp. 511-517
    • Capdevila, J.H.1    Pramanik, B.2    Napoli, J.L.3    Manna, S.4    Falck, J.R.5
  • 39
    • 0023882116 scopus 로고
    • NADPH-dependent microsomal metabolism of 14,15-epoxyeicosatrienoic acid to diepoxides and epoxyalcohols
    • Capdevila, J., P. Mosset, P. Yadagiri, Sun Lumin, and J. R. Falck. 1988. NADPH-dependent microsomal metabolism of 14,15-epoxyeicosatrienoic acid to diepoxides and epoxyalcohols. Arch. Biochem. Biophys. 261: 122-132.
    • (1988) Arch. Biochem. Biophys. , vol.261 , pp. 122-132
    • Capdevila, J.1    Mosset, P.2    Yadagiri, P.3    Lumin, S.4    Falck, J.R.5
  • 41
    • 0025311273 scopus 로고
    • Cytochrome P-450 enzyme-specific control of the regio- and enantiofacial selectivity of the microsomal AA epoxygenase
    • Capdevila, J. H., A. Karara, D. J. Waxman, M. V. Martin, J. R. Falck, and F. P. Guengerich. 1990. Cytochrome P-450 enzyme-specific control of the regio- and enantiofacial selectivity of the microsomal AA epoxygenase. J. Biol. Chem. 265: 10865-10871.
    • (1990) J. Biol. Chem. , vol.265 , pp. 10865-10871
    • Capdevila, J.H.1    Karara, A.2    Waxman, D.J.3    Martin, M.V.4    Falck, J.R.5    Guengerich, F.P.6
  • 43
    • 0027394892 scopus 로고
    • bis-Allylic hydroxylation of linoleic acid and AA by human hepatic monooxygenases Biochim
    • Oliw, E. H. 1993. bis-Allylic hydroxylation of linoleic acid and AA by human hepatic monooxygenases Biochim. Biophys. Acta. 1166: 258-263.
    • (1993) Biophys. Acta. , vol.1166 , pp. 258-263
    • Oliw, E.H.1
  • 44
    • 0029102061 scopus 로고
    • 7-HETE, 10-HETE, and 13-HETE are major products of NADPH-dependent AA metabolism in rat liver microsomes: Analysis of their stereochemistry, and the stereochemistry of their acid-catalyzed rearrangement
    • Brash, A. R., W. E. Boeglin, J. H. Capdevila, S. Yeola, and I. A. Blair. 1995. 7-HETE, 10-HETE, and 13-HETE are major products of NADPH-dependent AA metabolism in rat liver microsomes: analysis of their stereochemistry, and the stereochemistry of their acid-catalyzed rearrangement. Arch. Biochim. Biophys. 321: 485-492.
    • (1995) Arch. Biochim. Biophys. , vol.321 , pp. 485-492
    • Brash, A.R.1    Boeglin, W.E.2    Capdevila, J.H.3    Yeola, S.4    Blair, I.A.5
  • 45
    • 0022907609 scopus 로고
    • Absolute configuration of the hydroxyeicosatetraenoic acids (HETEs) formed during catalytic oxygenation of AA by microsomal cytochrome P-450
    • Capdevila, J. H., P. Yadagiri, S. Manna, and J. R. Falck. 1986. Absolute configuration of the hydroxyeicosatetraenoic acids (HETEs) formed during catalytic oxygenation of AA by microsomal cytochrome P-450. Biochem. Biophys. Res. Commun. 141: 1007-1011.
    • (1986) Biochem. Biophys. Res. Commun. , vol.141 , pp. 1007-1011
    • Capdevila, J.H.1    Yadagiri, P.2    Manna, S.3    Falck, J.R.4
  • 46
    • 0022450566 scopus 로고
    • Stereochemical differences between 12-hydroxy-5,8,10,14-eicosatetraenoic acid in platelets and psoriatic lesions
    • Woollard, P. M. 1986. Stereochemical differences between 12-hydroxy-5,8,10,14-eicosatetraenoic acid in platelets and psoriatic lesions. Biochem. Biophys. Res. Commun. 136: 169-176.
    • (1986) Biochem. Biophys. Res. Commun. , vol.136 , pp. 169-176
    • Woollard, P.M.1
  • 48
    • 0032499790 scopus 로고    scopus 로고
    • A 12R-lipoxygenase in human skin: Mechanistic evidence, molecular cloning, and expression
    • Boeglin, W. E., R. B. Kim, and A. R. Brash. 1998. A 12R-lipoxygenase in human skin: mechanistic evidence, molecular cloning, and expression. Proc. Natl. Acad. Sci. USA. 95: 6744-6749.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 6744-6749
    • Boeglin, W.E.1    Kim, R.B.2    Brash, A.R.3
  • 49
    • 20644448592 scopus 로고    scopus 로고
    • Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment
    • Sun, D., M. McDonnel, X. S. Chen, M. M. Lakkis, S. N. Isaacs, S. H. Elsea, P. I. Patel, and C. D. Funk. 1998. Human 12(R)-lipoxygenase and the mouse ortholog. Molecular cloning, expression, and gene chromosomal assignment. J. Biol. Chem. 273: 33540-33547.
    • (1998) J. Biol. Chem. , vol.273 , pp. 33540-33547
    • Sun, D.1    McDonnel, M.2    Chen, X.S.3    Lakkis, M.M.4    Isaacs, S.N.5    Elsea, S.H.6    Patel, P.I.7    Funk, C.D.8
  • 50
    • 0027506030 scopus 로고
    • Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by bovine corneal epithelium
    • Oliw, E. H. 1993. Biosynthesis of 12(S)-hydroxyeicosatetraenoic acid by bovine corneal epithelium. Acta. Physiol. Scand. 147: 117-121.
    • (1993) Acta. Physiol. Scand. , vol.147 , pp. 117-121
    • Oliw, E.H.1
  • 52
    • 0014670327 scopus 로고
    • Resolution of the cytochrome P-450-containing ω-hydroxylation system of liver microsomes into three components
    • Lu, A. Y. H., K. Junk, and M. J. Coon. 1969. Resolution of the cytochrome P-450-containing ω-hydroxylation system of liver microsomes into three components. J. Biol. Chem. 244: 3714-3721.
    • (1969) J. Biol. Chem. , vol.244 , pp. 3714-3721
    • Lu, A.Y.H.1    Junk, K.2    Coon, M.J.3
  • 55
    • 0024432048 scopus 로고
    • Role of hepatic and renal cytochrome P450 IVA1 in the metabolism of lipid substrates
    • Sharma, R. K., M. V. Doig, D. F. V. Lewis, and G. Gibson. 1989. Role of hepatic and renal cytochrome P450 IVA1 in the metabolism of lipid substrates. Biochem. Pharmacol. 38: 3621-3629.
    • (1989) Biochem. Pharmacol. , vol.38 , pp. 3621-3629
    • Sharma, R.K.1    Doig, M.V.2    Lewis, D.F.V.3    Gibson, G.4
  • 56
    • 0024381117 scopus 로고
    • ω and (ω1)-hydroxylation of lauric acid and AA by rat renal cytochrome P-450
    • Imaoka, S., S. Tanaka, and Y. Funae. 1989. ω and (ω1)-hydroxylation of lauric acid and AA by rat renal cytochrome P-450. Biochem. Int. 18: 731-740.
    • (1989) Biochem. Int. , vol.18 , pp. 731-740
    • Imaoka, S.1    Tanaka, S.2    Funae, Y.3
  • 57
    • 0024350111 scopus 로고
    • The rat clofibrate-inducible CYP4A gene subfamily I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization and identification of a conserved 19-bp upstream element
    • Kimura, S., N. Hanioka, E. Matsunaga, and F. J. Gonzalez. 1989. The rat clofibrate-inducible CYP4A gene subfamily I. Complete intron and exon sequence of the CYP4A1 and CYP4A2 genes, unique exon organization and identification of a conserved 19-bp upstream element. DNA. 8: 503-516.
    • (1989) DNA , vol.8 , pp. 503-516
    • Kimura, S.1    Hanioka, N.2    Matsunaga, E.3    Gonzalez, F.J.4
  • 58
    • 0024385160 scopus 로고
    • The rat clofibrate induicible CYP4A subfamily II. CDNA sequence of IVA3, mapping of the Cyp4a locus tomouse chromosome 4, and coordinated and tissue specific regulation of the CYP4A genes
    • Kimura, S., J. P. Hardwick, C. A. Kozac, and F. J. Gonzalez. 1989. The rat clofibrate induicible CYP4A subfamily II. cDNA sequence of IVA3, mapping of the Cyp4a locus tomouse chromosome 4, and coordinated and tissue specific regulation of the CYP4A genes. DNA. 8: 517-525.
    • (1989) DNA , vol.8 , pp. 517-525
    • Kimura, S.1    Hardwick, J.P.2    Kozac, C.A.3    Gonzalez, F.J.4
  • 59
    • 0025139362 scopus 로고
    • Characterization of three cytochrome P450s purified from renal microsomes of untreated male rats and comparison with human renal cytochrome P450
    • Imaoka, S., K. Nagashima, and Y. Funae. 1990. Characterization of three cytochrome P450s purified from renal microsomes of untreated male rats and comparison with human renal cytochrome P450. Arch. Biochem. Biophys. 276: 473-480.
    • (1990) Arch. Biochem. Biophys. , vol.276 , pp. 473-480
    • Imaoka, S.1    Nagashima, K.2    Funae, Y.3
  • 60
    • 0025027879 scopus 로고
    • Cloning and characterization of a novel member of the cytochrome P450 subfamily IVA in rat prostate
    • Stromsteadt, M., S. Hayashi, P. G. Zaphiropoulos, and J. A. Gustafsson. 1990. Cloning and characterization of a novel member of the cytochrome P450 subfamily IVA in rat prostate. DNA Cell Biol. 8: 569-577.
    • (1990) DNA Cell Biol. , vol.8 , pp. 569-577
    • Stromsteadt, M.1    Hayashi, S.2    Zaphiropoulos, P.G.3    Gustafsson, J.A.4
  • 66
    • 0027287448 scopus 로고
    • Catalytic properties of rabbit kidney fatty acid ω-hydroxylase cytochrome P-450ka2 (CYP4A7)
    • Sawamura, A., E. Kusunose, K. Satouchi, and M. Kusunose. 1993. Catalytic properties of rabbit kidney fatty acid ω-hydroxylase cytochrome P-450ka2 (CYP4A7). Biochim. Biophys. Acta. 1168: 30-36.
    • (1993) Biochim. Biophys. Acta. , vol.1168 , pp. 30-36
    • Sawamura, A.1    Kusunose, E.2    Satouchi, K.3    Kusunose, M.4
  • 67
    • 0027459403 scopus 로고
    • Characterization of a cDNA encoding a human kidney cytochrome P-450 4A fatty acid ω-hydroxylase and the cognate enzyme expressed in Escherichia coli
    • Palmer, C. N. A., T. H. Richardson, K. J. Griffin, M. Hsu, A. S. Muerhoff, J. E. Clark, and E. F. Johnson. 1993. Characterization of a cDNA encoding a human kidney cytochrome P-450 4A fatty acid ω-hydroxylase and the cognate enzyme expressed in Escherichia coli. Biochim. Biophys. Acta. 1172: 161-166.
    • (1993) Biochim. Biophys. Acta. , vol.1172 , pp. 161-166
    • Palmer, C.N.A.1    Richardson, T.H.2    Griffin, K.J.3    Hsu, M.4    Muerhoff, A.S.5    Clark, J.E.6    Johnson, E.F.7
  • 68
    • 0027739613 scopus 로고
    • Complete cDNA sequence and cDNA-directed expression of CYP4A11, a fatty acid omega-hydroxylase expressed in human kidney
    • Imaoka, S., H. Ogawa, S. Kimura, and F. J. Gonzalez. 1993. Complete cDNA sequence and cDNA-directed expression of CYP4A11, a fatty acid omega-hydroxylase expressed in human kidney. DNA Cell Biol. 12: 893-899.
    • (1993) DNA Cell Biol. , vol.12 , pp. 893-899
    • Imaoka, S.1    Ogawa, H.2    Kimura, S.3    Gonzalez, F.J.4
  • 69
    • 0032997280 scopus 로고    scopus 로고
    • Kinetic profile of the rat CYP4A isoforms: Arachidonic acid metabolism and isoform specific inhibitors
    • Nguyen, X., M-H. Wang, K. M. Reddy, J. R. Falck, and M. L. Schwartzman. 1999. Kinetic profile of the rat CYP4A isoforms: arachidonic acid metabolism and isoform specific inhibitors. Am. J. Physiol. 276: R1691-R1700.
    • (1999) Am. J. Physiol. , vol.276
    • Nguyen, X.1    Wang, M.-H.2    Reddy, K.M.3    Falck, J.R.4    Schwartzman, M.L.5
  • 70
    • 0030589540 scopus 로고    scopus 로고
    • Cloning, sequencing, and cDNA-direcled expression of rat renal CYP4A2: AA ω-hydroxylation and 11,12-epoxidation by CYP4A2 protein
    • Wang, M. H., D. E. Stec, M. Balazy, V. Mastyugin, C. S. Yang, R. J. Roman, and M. L. Schwartzman. 1997. Cloning, sequencing, and cDNA-direcled expression of rat renal CYP4A2: AA ω-hydroxylation and 11,12-epoxidation by CYP4A2 protein. Arch. Biochem. Biophys. 336: 240-250.
    • (1997) Arch. Biochem. Biophys. , vol.336 , pp. 240-250
    • Wang, M.H.1    Stec, D.E.2    Balazy, M.3    Mastyugin, V.4    Yang, C.S.5    Roman, R.J.6    Schwartzman, M.L.7
  • 71
    • 0032497411 scopus 로고    scopus 로고
    • Molecular, enzymatic, and regulatory characterization of rat kidney cytochromes P450 4A2 and 4A3
    • Helvig, C., E. Dishman, and J. H. Capdevila. 1998. Molecular, enzymatic, and regulatory characterization of rat kidney cytochromes P450 4A2 and 4A3. Biochemistry. 37: 12546-12558.
    • (1998) Biochemistry , vol.37 , pp. 12546-12558
    • Helvig, C.1    Dishman, E.2    Capdevila, J.H.3
  • 72
    • 0029796038 scopus 로고    scopus 로고
    • Role of the peroxisome-activated receptor in cytochrome P450 4A gene regulation
    • and references therein
    • Johnson, E. F., C. A. N. Palmer, K. J. Griffin, and H. Mei-Hui. 1996. Role of the peroxisome-activated receptor in cytochrome P450 4A gene regulation. FASEB J. 10: 1241-1248 and references therein.
    • (1996) FASEB J. , vol.10 , pp. 1241-1248
    • Johnson, E.F.1    Palmer, C.A.N.2    Griffin, K.J.3    Mei-Hui, H.4
  • 74
    • 0024416301 scopus 로고
    • Differential induction of peroxisomal and microsomal fatty-acid-oxidising enzymes by peroxisome proliferators in rat liver and kidney
    • Sharma, R. K., B. G,. Lake, R. Makowski, T. Bradshaw, D. Earnshaw, J. W. Dale, and G. G. Gibson. 1989. Differential induction of peroxisomal and microsomal fatty-acid-oxidising enzymes by peroxisome proliferators in rat liver and kidney. Eur. J. Biochem. 184: 69-78.
    • (1989) Eur. J. Biochem. , vol.184 , pp. 69-78
    • Sharma, R.K.1    Lake, B.G.2    Makowski, R.3    Bradshaw, T.4    Earnshaw, D.5    Dale, J.W.6    Gibson, G.G.7
  • 75
    • 0024421162 scopus 로고
    • Nutritionally triggered alterations in the regiospecificity of AA oxygenation by rat liver microsomal cytochrome P450
    • Orellana, M., E. Valdes, J. H. Capdevila, and L. Gil. 1989. Nutritionally triggered alterations in the regiospecificity of AA oxygenation by rat liver microsomal cytochrome P450. Arch. Biochem. Biophys. 274: 251-258.
    • (1989) Arch. Biochem. Biophys. , vol.274 , pp. 251-258
    • Orellana, M.1    Valdes, E.2    Capdevila, J.H.3    Gil, L.4
  • 76
    • 0032553545 scopus 로고    scopus 로고
    • Peroxisome proliferator-activated receptor alpha controls hepatic CYP4A induction adaptive response to starvation and diabetes
    • Kroetz, D. L., P. Yook, P. Costet, P. Bianchi, and T. Pineau. 1998. Peroxisome proliferator-activated receptor alpha controls hepatic CYP4A induction adaptive response to starvation and diabetes. J. Biol. Chem. 273: 31581-31589.
    • (1998) J. Biol. Chem. , vol.273 , pp. 31581-31589
    • Kroetz, D.L.1    Yook, P.2    Costet, P.3    Bianchi, P.4    Pineau, T.5
  • 77
    • 0033199499 scopus 로고    scopus 로고
    • P450 gene induction by structurally diverse xenochemicals: Central role of nuclear receptors CAR, PXR, and PPAR
    • Waxman, D. J. 1999. P450 gene induction by structurally diverse xenochemicals: central role of nuclear receptors CAR, PXR, and PPAR. Arch. Biochem. Biophys. 369: 11-23.
    • (1999) Arch. Biochem. Biophys. , vol.369 , pp. 11-23
    • Waxman, D.J.1
  • 78
    • 0027164207 scopus 로고
    • Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome 450 2E1
    • Laethem, R. M., M. Balazy, D. R. Falck, C. L. Laethem, and D. R. Koop. 1993. Formation of 19(S)-, 19(R)-, and 18(R)-hydroxyeicosatetraenoic acids by alcohol-inducible cytochrome 450 2E1. J. Biol. Chem. 268: 12912-12918.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12912-12918
    • Laethem, R.M.1    Balazy, M.2    Falck, D.R.3    Laethem, C.L.4    Koop, D.R.5
  • 80
    • 0028071185 scopus 로고
    • Purification and biochemical characterization of two major cytochrome P-450 isoforms induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in chick embryo liver
    • Rifkind, A. B., A. Kanetoshi, J. Orlinick, J. H. Capdevila, and C. Lee. 1994. Purification and biochemical characterization of two major cytochrome P-450 isoforms induced by 2,3,7,8-tetrachlorodibenzo-p-dioxin in chick embryo liver. J. Biol. Chem. 269: 3387-3396.
    • (1994) J. Biol. Chem. , vol.269 , pp. 3387-3396
    • Rifkind, A.B.1    Kanetoshi, A.2    Orlinick, J.3    Capdevila, J.H.4    Lee, C.5
  • 81
    • 0030849408 scopus 로고    scopus 로고
    • A novel murine gene, Cyp4a14, is part of a cluster of Cyp4a and 4b, but not Cyp4F genes in mouse and humans
    • Heng, Y. M., S. Kuo, P. S. Jones, R. Savory, R. M. Schultz, S. R. Tomlinson, T. J. Gray, and D. R. Bell. 1997. A novel murine gene, Cyp4a14, is part of a cluster of Cyp4a and 4b, but not Cyp4F genes in mouse and humans. Biochem. J. 325: 741-749.
    • (1997) Biochem. J. , vol.325 , pp. 741-749
    • Heng, Y.M.1    Kuo, S.2    Jones, P.S.3    Savory, R.4    Schultz, R.M.5    Tomlinson, S.R.6    Gray, T.J.7    Bell, D.R.8
  • 82
    • 0026671184 scopus 로고
    • Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid omega-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone
    • Sundseth, S. S., and D. J. Waxman. 1992. Sex-dependent expression and clofibrate inducibility of cytochrome P450 4A fatty acid omega-hydroxylases. Male specificity of liver and kidney CYP4A2 mRNA and tissue-specific regulation by growth hormone and testosterone. J. Biol. Chem. 267: 3915-3921.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3915-3921
    • Sundseth, S.S.1    Waxman, D.J.2
  • 83
    • 0019979537 scopus 로고
    • Oxygenation of AA by hepatic monooxygenases
    • Oliw, E. H., F. P. Guengerich, and J. A. Oates. 1982. Oxygenation of AA by hepatic monooxygenases. J. Biol. Chem. 257: 3771-3781.
    • (1982) J. Biol. Chem. , vol.257 , pp. 3771-3781
    • Oliw, E.H.1    Guengerich, F.P.2    Oates, J.A.3
  • 85
    • 0024331440 scopus 로고
    • Endogenous epoxyeicosatrienoic acids. Cytochrome P-450 controlled stereoselectivity of the hepatic AA epoxygenase
    • Karara, A., E. Dishman, I. Blair, J. R. Falck, and J. H. Capdevila. 1989. Endogenous epoxyeicosatrienoic acids. Cytochrome P-450 controlled stereoselectivity of the hepatic AA epoxygenase. J. Biol. Chem. 264: 19822-19827.
    • (1989) J. Biol. Chem. , vol.264 , pp. 19822-19827
    • Karara, A.1    Dishman, E.2    Blair, I.3    Falck, J.R.4    Capdevila, J.H.5
  • 86
    • 0025292663 scopus 로고
    • Arachidonic acid epoxygenase. Stereochemical analysis of the endogenous epoxyeicosatrienoic acids of human kidney cortex
    • Karara, A., E. Dishman, H. Jacobson, J. R. Falck, and J. H. Capdevila. 1990. Arachidonic acid epoxygenase. Stereochemical analysis of the endogenous epoxyeicosatrienoic acids of human kidney cortex. FEBS Lett. 268: 227-230.
    • (1990) FEBS Lett. , vol.268 , pp. 227-230
    • Karara, A.1    Dishman, E.2    Jacobson, H.3    Falck, J.R.4    Capdevila, J.H.5
  • 88
    • 0026523719 scopus 로고
    • AA epoxygenase: Structural characterization and quantification of epoxyeicosatrienoates in plasma
    • Karara, A., S. Wei, D. Spady, L. Swift, J. H. Capdevila, and J. R. Falck. 1992. AA epoxygenase: structural characterization and quantification of epoxyeicosatrienoates in plasma. Biochem. Biophys. Res. Commun. 182: 1320-1325.
    • (1992) Biochem. Biophys. Res. Commun. , vol.182 , pp. 1320-1325
    • Karara, A.1    Wei, S.2    Spady, D.3    Swift, L.4    Capdevila, J.H.5    Falck, J.R.6
  • 90
    • 0023145143 scopus 로고
    • Transformation of an arachidonicacid hydroperoxide into epoxyhydroxy and trihydroxy fatty acids by liver microsomal cytochrome P-450
    • Weiss, R. H., J. L. Arnold, and R. W. Estabrook. 1987. Transformation of an arachidonicacid hydroperoxide into epoxyhydroxy and trihydroxy fatty acids by liver microsomal cytochrome P-450. Arch. Biochim. Biophys. 252: 334-338.
    • (1987) Arch. Biochim. Biophys. , vol.252 , pp. 334-338
    • Weiss, R.H.1    Arnold, J.L.2    Estabrook, R.W.3
  • 91
    • 0027493771 scopus 로고
    • Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 AA epoxygenase
    • Karara, A., K. Makita, H. R. Jacobson, J. R. Falck, F. P. Guengerich, R. N. DuBois, and J. H. Capdevila. 1993. Molecular cloning, expression, and enzymatic characterization of the rat kidney cytochrome P-450 AA epoxygenase. J. Biol. Chem. 268: 13565-13570.
    • (1993) J. Biol. Chem. , vol.268 , pp. 13565-13570
    • Karara, A.1    Makita, K.2    Jacobson, H.R.3    Falck, J.R.4    Guengerich, F.P.5    DuBois, R.N.6    Capdevila, J.H.7
  • 92
    • 0029122098 scopus 로고
    • Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform
    • Zeldin, D. C., R. N. DuBois, J. R. Falck, and J. H. Capdevila. 1995. Molecular cloning, expression and characterization of an endogenous human cytochrome P450 arachidonic acid epoxygenase isoform. Arch. Biochem. Biophys. 322: 76-86.
    • (1995) Arch. Biochem. Biophys. , vol.322 , pp. 76-86
    • Zeldin, D.C.1    DuBois, R.N.2    Falck, J.R.3    Capdevila, J.H.4
  • 93
    • 0028337479 scopus 로고
    • Stereoselective epoxidation of AA by cytochrome P-450s 2CAA and 2C2
    • Daikh, B. E., R. M. Laethem, and D. Koop. 1994. Stereoselective epoxidation of AA by cytochrome P-450s 2CAA and 2C2. J. Pharmacol. Exp. Ther. 269: 1130-1135.
    • (1994) J. Pharmacol. Exp. Ther. , vol.269 , pp. 1130-1135
    • Daikh, B.E.1    Laethem, R.M.2    Koop, D.3
  • 94
    • 0031057495 scopus 로고    scopus 로고
    • Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas
    • Zeldin, D. C., J. Foley, J. E. Boyle, C. R. Moomaw, K. B. Tomer, C. Parker, C. Steenbergen, and S. Wu. 1997. Predominant expression of an arachidonate epoxygenase in islets of Langerhans cells in human and rat pancreas. Endocrinology. 138: 1338-1346.
    • (1997) Endocrinology , vol.138 , pp. 1338-1346
    • Zeldin, D.C.1    Foley, J.2    Boyle, J.E.3    Moomaw, C.R.4    Tomer, K.B.5    Parker, C.6    Steenbergen, C.7    Wu, S.8
  • 95
    • 0030063499 scopus 로고    scopus 로고
    • Molecular cloning and expression of CYP2J2, a human cytochrome P450 AA epoxygenase highly expressed in heart
    • Wu, S., C. R. Moomaw, K. B. Tomer, J. R. Falck, and D. C. Zeldin 1996. Molecular cloning and expression of CYP2J2, a human cytochrome P450 AA epoxygenase highly expressed in heart. J. Biol. Chem. 271: 3460-3468.
    • (1996) J. Biol. Chem. , vol.271 , pp. 3460-3468
    • Wu, S.1    Moomaw, C.R.2    Tomer, K.B.3    Falck, J.R.4    Zeldin, D.C.5
  • 96
    • 0032502795 scopus 로고    scopus 로고
    • A keratinocyte-specific epoxygenase, CYP2B12, metabolites AA with unusual selectivity, producing a single major epoxyeicosatrienoic acid
    • Keeney, D. S., C. Skinner, S. Wei, T. Friedberg, and M. R. Waterman. 1998. A keratinocyte-specific epoxygenase, CYP2B12, metabolites AA with unusual selectivity, producing a single major epoxyeicosatrienoic acid. J. Biol. Chem. 273: 9279-9284.
    • (1998) J. Biol. Chem. , vol.273 , pp. 9279-9284
    • Keeney, D.S.1    Skinner, C.2    Wei, S.3    Friedberg, T.4    Waterman, M.R.5
  • 97
    • 0028340912 scopus 로고
    • Bioactivation of AA by the cytochrome P450 monooxygense of guinea pig lung: The orthologue of cytochrome P450 2B4 is solely responsible for the formation of epoxyeicosatrienoic acids
    • Knickle, L. C., and J. R. Bend. 1994. Bioactivation of AA by the cytochrome P450 monooxygense of guinea pig lung: the orthologue of cytochrome P450 2B4 is solely responsible for the formation of epoxyeicosatrienoic acids. Mol. Pharmacol. 45: 1273-1280.
    • (1994) Mol. Pharmacol. , vol.45 , pp. 1273-1280
    • Knickle, L.C.1    Bend, J.R.2
  • 98
    • 0033610838 scopus 로고    scopus 로고
    • Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity
    • Keeney, D. S., C. Skinner, J. B. Travers, J. H. Capdevila, L. B. Nanney, L. E. King, and M. Waterman. 1998. Differentiating keratinocytes express a novel cytochrome P450 enzyme, CYP2B19, having arachidonate monooxygenase activity. J. Biol. Chem. 273: 32071-32079.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32071-32079
    • Keeney, D.S.1    Skinner, C.2    Travers, J.B.3    Capdevila, J.H.4    Nanney, L.B.5    King, L.E.6    Waterman, M.7
  • 100
    • 0032725975 scopus 로고    scopus 로고
    • The kidney cytochrome P450 2C23 AA epoxygenase is upregulated during dietary salt loading
    • Holla, V. R., K. Makita, P. G. Zaphiropoulos, and J. H. Capdevila. 1999. The kidney cytochrome P450 2C23 AA epoxygenase is upregulated during dietary salt loading. J. Clin. Invest. 104: 751-760.
    • (1999) J. Clin. Invest. , vol.104 , pp. 751-760
    • Holla, V.R.1    Makita, K.2    Zaphiropoulos, P.G.3    Capdevila, J.H.4
  • 101
    • 0028283819 scopus 로고
    • Epoxidation of AA as an active site probe of cytochrome P450 2B isoforms
    • Laethem, R. M., J. R. Halpert, and D. R. Koop. 1994. Epoxidation of AA as an active site probe of cytochrome P450 2B isoforms. Biochim. Biophys. Acta. 1206: 42-48.
    • (1994) Biochim. Biophys. Acta. , vol.1206 , pp. 42-48
    • R, M.1    Halpert, J.R.2    Koop, D.R.3
  • 103
    • 0031021585 scopus 로고    scopus 로고
    • An active site substitution, F87V, converts cytochrome P450 BM3 into a regio- and stereoselective (14)S, 15(R)-AA epoxygenase
    • Graham-Lorence, S., G. Truan, J. A. Peterson, J. R. Falck, S. Wei, C. Helvig, and J. H. Capdevila. 1997. An active site substitution, F87V, converts cytochrome P450 BM3 into a regio- and stereoselective (14)S, 15(R)-AA epoxygenase. J. Biol. Chem. 272: 1127-1135.
    • (1997) J. Biol. Chem. , vol.272 , pp. 1127-1135
    • Graham-Lorence, S.1    Truan, G.2    Peterson, J.A.3    Falck, J.R.4    Wei, S.5    Helvig, C.6    Capdevila, J.H.7
  • 105
    • 0026275338 scopus 로고
    • Hormonal regulation of cytochrome P450 gene expression
    • and references therein
    • Lund, J., P. G. Zaphiropoulos, A. Mode, M. Warner, and J. A. Gustafsson. 1991. Hormonal regulation of cytochrome P450 gene expression. Adv. Pharmacol. 22: 325-354 and references therein.
    • (1991) Adv. Pharmacol. , vol.22 , pp. 325-354
    • Lund, J.1    Zaphiropoulos, P.G.2    Mode, A.3    Warner, M.4    Gustafsson, J.A.5
  • 106
    • 0025773636 scopus 로고
    • Endogenous epoxyeicosatrienoyl-phospholipids. A novel class of cellular glycerolipids containing epoxidized arachidonate moieties
    • Karara, A., E. Dishman, J. R. Falck, and J. H. Capdevila. 1991. Endogenous epoxyeicosatrienoyl-phospholipids. A novel class of cellular glycerolipids containing epoxidized arachidonate moieties. J. Biol. Chem. 266: 7561-7569.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7561-7569
    • Karara, A.1    Dishman, E.2    Falck, J.R.3    Capdevila, J.H.4
  • 107
    • 0025180599 scopus 로고
    • Selective incorporation of 15(S)-hydroxyeiosatetraenoic acid in phosphatidylinositol of human neutrophils: Agonist-induced deacylation and transformation of stored hydroxyeicosanoids
    • Brezinski, M., and C. N. Serhan. 1990. Selective incorporation of 15(S)-hydroxyeiosatetraenoic acid in phosphatidylinositol of human neutrophils: agonist-induced deacylation and transformation of stored hydroxyeicosanoids. Proc. Natl Acad. Sci. USA. 87: 6248-6252.
    • (1990) Proc. Natl Acad. Sci. USA , vol.87 , pp. 6248-6252
    • Brezinski, M.1    Serhan, C.N.2
  • 108
    • 0025776836 scopus 로고
    • Substitution of 15-hydroxyeicosatetraenoic acid in the phosphomositide signaling pathway
    • Legrand, A. B., J. A. Lawson, B. O. Meyrick, I. A. Blair, and J. A. Oates. 1991. Substitution of 15-hydroxyeicosatetraenoic acid in the phosphomositide signaling pathway. J. Biol. Chem. 266: 7570-7577.
    • (1991) J. Biol. Chem. , vol.266 , pp. 7570-7577
    • Legrand, A.B.1    Lawson, J.A.2    Meyrick, B.O.3    Blair, I.A.4    Oates, J.A.5
  • 109
    • 0026728159 scopus 로고
    • Incorporation and distribution of epoxyeicosatrienoic acids into cellular phospholipids
    • Bernstrom, K., K. Kayganich, R. C. Murphy, and F. A. Fitzpatrick, 1992. Incorporation and distribution of epoxyeicosatrienoic acids into cellular phospholipids. J. Biol. Chem. 267: 3686-3690.
    • (1992) J. Biol. Chem. , vol.267 , pp. 3686-3690
    • Bernstrom, K.1    Kayganich, K.2    Murphy, R.C.3    Fitzpatrick, F.A.4
  • 111
    • 0021779906 scopus 로고
    • Mechanisms and consequences of lipid peroxidation in biological systems
    • and references therein
    • Sevanian, A., and P. Hochstein. 1985. Mechanisms and consequences of lipid peroxidation in biological systems. Annu. Rev. Nutr: 5: 365-390 and references therein.
    • (1985) Annu. Rev. Nutr , vol.5 , pp. 365-390
    • Sevanian, A.1    Hochstein, P.2
  • 113
    • 0002259565 scopus 로고
    • Lipid structure
    • Y. Philip, editor. CRC. Press, Ann Arbor, MI and references therein
    • Hauser, H., and G. Poupart. 1992. Lipid structure. In The Structure of Biological Membranes. Y. Philip, editor. CRC. Press, Ann Arbor, MI. 3-71 and references therein.
    • (1992) The Structure of Biological Membranes , pp. 3-71
    • Hauser, H.1    Poupart, G.2
  • 114
    • 0013550699 scopus 로고
    • The dynamics of membrane lipids
    • Y. Philip, editor. CRC Press, Ann Arbor, MI and references therein
    • Yeagle, P. 1992. The dynamics of membrane lipids. In The Structure of Biological Membranes. Y. Philip, editor. CRC Press, Ann Arbor, MI. 157-174 and references therein.
    • (1992) The Structure of Biological Membranes , pp. 157-174
    • Yeagle, P.1
  • 115
    • 0005181431 scopus 로고
    • Cytochrome P450 epoxygenase dependent formation of novel endogenous epoxyeicosatrienoyl-phospholipids
    • S. Nigam, L. J. Marnett, K. V. Honn, and T. L. Walden, Jr., editors. Kluwer Academic Publishers, Boston, MA
    • Capdevila, J. H., Y. Jin, A. Karara, and J. R. Falck. 1993. Cytochrome P450 epoxygenase dependent formation of novel endogenous epoxyeicosatrienoyl-phospholipids. In Eicosanoids and Other Bioactive Lipids in Cancer, Inflamation and Radiation Injury S. Nigam, L. J. Marnett, K. V. Honn, and T. L. Walden, Jr., editors. Kluwer Academic Publishers, Boston, MA. 11-15.
    • (1993) Eicosanoids and Other Bioactive Lipids in Cancer, Inflamation and Radiation Injury , pp. 11-15
    • Capdevila, J.H.1    Jin, Y.2    Karara, A.3    Falck, J.R.4
  • 116
    • 0033056018 scopus 로고    scopus 로고
    • Inhibition of cardiac L-type calcium channels by epoxyeicosatrienoic acids
    • Chen, J., J. H. Capdevila, D. C. Zeldin, and R. L. Rosenberg. 1999. Inhibition of cardiac L-type calcium channels by epoxyeicosatrienoic acids. Mol. Pharmacol. 55: 288-295.
    • (1999) Mol. Pharmacol. , vol.55 , pp. 288-295
    • Chen, J.1    Capdevila, J.H.2    Zeldin, D.C.3    Rosenberg, R.L.4
  • 117
    • 0025234405 scopus 로고
    • Inhibition of renin release by 14, 15-epoxyeicosatrienoic acid in renal cortical slices
    • Henrich, W. L., J. R. Falck, and W. B. Campbell. 1990. Inhibition of renin release by 14, 15-epoxyeicosatrienoic acid in renal cortical slices. Am. J. Physiol. 258: E269-274.
    • (1990) Am. J. Physiol. , vol.258
    • Henrich, W.L.1    Falck, J.R.2    Campbell, W.B.3
  • 118
    • 0026485525 scopus 로고
    • Inhibition of renin secretion from rat renal cortical slices by (R)-12-HETE
    • Henrich, W. L., J. R. Falck, and W. B. Campbell. 1992. Inhibition of renin secretion from rat renal cortical slices by (R)-12-HETE. Am. J. Physiol. 263: F665-670.
    • (1992) Am. J. Physiol. , vol.263
    • Henrich, W.L.1    Falck, J.R.2    Campbell, W.B.3
  • 119
    • 0033525767 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonir acid in the regulation of tone
    • Campbell, W. B., and D. R. Harder. 1999. Endothelium-derived hyperpolarizing factors and vascular cytochrome P450 metabolites of arachidonir acid in the regulation of tone. Circ. Res. 84: 484-488.
    • (1999) Circ. Res. , vol.84 , pp. 484-488
    • Campbell, W.B.1    Harder, D.R.2
  • 120
    • 0027471234 scopus 로고
    • Role of cytochrome P-450 in elevating renal vascular tone in spontaneously hypertensive rats
    • Gebremedhin, D., Y. H. Ma, J. D. Imig, D. R. Harder, and R. J. Roman. 1993. Role of cytochrome P-450 in elevating renal vascular tone in spontaneously hypertensive rats. J. Vasc. Res. 30: 53-60.
    • (1993) J. Vasc. Res. , vol.30 , pp. 53-60
    • Gebremedhin, D.1    Ma, Y.H.2    Imig, J.D.3    Harder, D.R.4    Roman, R.J.5
  • 123
    • 0030028233 scopus 로고    scopus 로고
    • Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles
    • Imig, J. D., A. P. Zou, D. E. Stec, D. R. Harder, J. R. Falck, and R. J. Roman. 1996. Formation and actions of 20-hydroxyeicosatetraenoic acid in rat renal arterioles. Am. J. Physiol. 270: R217-R227.
    • (1996) Am. J. Physiol. , vol.270
    • Imig, J.D.1    Zou, A.P.2    Stec, D.E.3    Harder, D.R.4    Falck, J.R.5    Roman, R.J.6
  • 124
    • 0030774838 scopus 로고    scopus 로고
    • 20-Hydroxyeicosatetraenoic acid-induced vasoconstriction and inhibition of potassium current in cerebral vascular smooth muscle is dependent on activation of protein kinase C
    • Lange, A., D. Gebremedhin, J. Narayanan, and D. Harder. 1997. 20-Hydroxyeicosatetraenoic acid-induced vasoconstriction and inhibition of potassium current in cerebral vascular smooth muscle is dependent on activation of protein kinase C. J. Biol. Chem. 272: 27345-27352.
    • (1997) J. Biol. Chem. , vol.272 , pp. 27345-27352
    • Lange, A.1    Gebremedhin, D.2    Narayanan, J.3    Harder, D.4
  • 125
    • 0024581110 scopus 로고
    • Vasoactivity of 20-hydroxyeicosatetraenoic acid is dependent on metabolism by cyclooxygenase
    • Escalante, B., W. C. Sessa, J. R. Falck, P. Yadagiri, and M. L. Schwartzman. 1989. Vasoactivity of 20-hydroxyeicosatetraenoic acid is dependent on metabolism by cyclooxygenase. J. Pharmacol. Exp. Ther. 248: 229-232.
    • (1989) J. Pharmacol. Exp. Ther. , vol.248 , pp. 229-232
    • Escalante, B.1    Sessa, W.C.2    Falck, J.R.3    Yadagiri, P.4    Schwartzman, M.L.5
  • 126
    • 0031935515 scopus 로고    scopus 로고
    • 20-HETE relaxes bovine coronary arteries through the release of prostacyclin
    • Pratt, P. F., J. R. Falck, K. M. Reddy, J. B. Kurian, and W. B. Campbell. 1998. 20-HETE relaxes bovine coronary arteries through the release of prostacyclin. Hypertension. 31: 237-241.
    • (1998) Hypertension , vol.31 , pp. 237-241
    • Pratt, P.F.1    Falck, J.R.2    Reddy, K.M.3    Kurian, J.B.4    Campbell, W.B.5
  • 128
    • 0026567720 scopus 로고
    • Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites
    • Carroll, M. A., M. P. Garcia, J. R. Falck, and J. C. McGiff. 1992. Cyclooxygenase dependency of the renovascular actions of cytochrome P450-derived arachidonate metabolites. J. Pharmacol. Exp. Ther. 260: 104-109.
    • (1992) J. Pharmacol. Exp. Ther. , vol.260 , pp. 104-109
    • Carroll, M.A.1    Garcia, M.P.2    Falck, J.R.3    McGiff, J.C.4
  • 129
    • 0025214061 scopus 로고
    • Cytochrome P-450 arachidonate metabolites in rat kidney: Characterization and hemodynamic responses
    • Takahashi, K., J. Capdevila, A. Karara, J. R. Falck, H. R. Jacobson, and K. F. Badr. 1990. Cytochrome P-450 arachidonate metabolites in rat kidney: characterization and hemodynamic responses. Am. J. Physiol. 258: F781-F789.
    • (1990) Am. J. Physiol. , vol.258
    • Takahashi, K.1    Capdevila, J.2    Karara, A.3    Falck, J.R.4    Jacobson, H.R.5    Badr, K.F.6
  • 130
    • 0023795435 scopus 로고
    • Modulation of vascular tone by 12(R)-, but not 12(S)-hydroxyeicosatetraenoic acid
    • Masferrer, J., and K. M. Mullane. 1988. Modulation of vascular tone by 12(R)-, but not 12(S)-hydroxyeicosatetraenoic acid. Eur. J. Pharmacol 151: 487-490.
    • (1988) Eur. J. Pharmacol , vol.151 , pp. 487-490
    • Masferrer, J.1    Mullane, K.M.2
  • 131
    • 0029907840 scopus 로고    scopus 로고
    • Cytochrome P-450-dependent HETEs: Profile of biological activity and stimulation by vasoactive peptides
    • Carroll, M. A., M. Balazy, P. Margiotta, D. D. Huang, J. R. Falck, and J. C. McGiff. 1996. Cytochrome P-450-dependent HETEs: profile of biological activity and stimulation by vasoactive peptides. Am. J. Physiol. 271: R863-R869.
    • (1996) Am. J. Physiol. , vol.271
    • Carroll, M.A.1    Balazy, M.2    Margiotta, P.3    Huang, D.D.4    Falck, J.R.5    McGiff, J.C.6
  • 132
    • 0030051805 scopus 로고    scopus 로고
    • Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors
    • Campbell, W. B., D. Gebremedhin, P. F. Pratt, and D. R. Harder. 1996. Identification of epoxyeicosatrienoic acids as endothelium-derived hyperpolarizing factors. Circ. Res. 78: 415-123.
    • (1996) Circ. Res. , vol.78 , pp. 415-1123
    • Campbell, W.B.1    Gebremedhin, D.2    Pratt, P.F.3    Harder, D.R.4
  • 133
    • 0025153829 scopus 로고
    • 5,6-Epoxyeicosatrienoic acid, a novel arachidonate metabolite. Mechanism of vasoactivity in the rat
    • Carroll, M. A., M. P. Garcia, J. R. Falck, and J. C. McGiff. 1990. 5,6-Epoxyeicosatrienoic acid, a novel arachidonate metabolite. Mechanism of vasoactivity in the rat. Circ. Res. 67: 1082-1088.
    • (1990) Circ. Res. , vol.67 , pp. 1082-1088
    • Carroll, M.A.1    Garcia, M.P.2    Falck, J.R.3    McGiff, J.C.4
  • 134
    • 0030391673 scopus 로고    scopus 로고
    • Nitric oxide and prostaglandins mediate vasodilation to 5,6-EET in rabbit lung
    • Tan, J. Z., G. Kaley, and G. H. Gurtner. 1997. Nitric oxide and prostaglandins mediate vasodilation to 5,6-EET in rabbit lung. Adv. Exp. Med. Biol. 407: 561-566.
    • (1997) Adv. Exp. Med. Biol. , vol.407 , pp. 561-566
    • Tan, J.Z.1    Kaley, G.2    Gurtner, G.H.3
  • 135
    • 0030426730 scopus 로고    scopus 로고
    • Possible contribution of platelet cyclooxygenase to the renal vascular action of 5,6-epoxyeicosatrienoic acid
    • Fulton, D., M. Balazy, J. C. McGiff, and J. Quilley. 1996. Possible contribution of platelet cyclooxygenase to the renal vascular action of 5,6-epoxyeicosatrienoic acid. J. Pharmacol. Exp. Ther. 277: 1195-1199.
    • (1996) J. Pharmacol. Exp. Ther. , vol.277 , pp. 1195-1199
    • Fulton, D.1    Balazy, M.2    McGiff, J.C.3    Quilley, J.4
  • 136
    • 0027233724 scopus 로고
    • Renal vasodilator activity of 5,6-epoxyeicosatrienoic acid depends upon conversion by cyclooxygenase and release of prostaglandins
    • Carroll, M. A., M. Balazy, P. Margiotta, J. R. Falck, and J. C. McGiff. 1993. Renal vasodilator activity of 5,6-epoxyeicosatrienoic acid depends upon conversion by cyclooxygenase and release of prostaglandins. J. Biol. Chem. 268: 12260-12266.
    • (1993) J. Biol. Chem. , vol.268 , pp. 12260-12266
    • Carroll, M.A.1    Balazy, M.2    Margiotta, P.3    Falck, J.R.4    McGiff, J.C.5
  • 140
    • 0023133288 scopus 로고
    • Intestinal vasodilation by epoxyeicosatrienoic acids: Arachidonic acid metabolites produced by a cytochrome P450 moonooxygenase
    • Proctor, K. G., R. Falck, and J. Capdevila. 1987. Intestinal vasodilation by epoxyeicosatrienoic acids: arachidonic acid metabolites produced by a cytochrome P450 moonooxygenase. Circ. Res. 60: 50-59.
    • (1987) Circ. Res. , vol.60 , pp. 50-59
    • Proctor, K.G.1    Falck, R.2    Capdevila, J.3
  • 141
    • 0025990867 scopus 로고
    • Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney
    • Katoh, T., K. Takahashi, J. Capdevila, A. Karara, J. R. Falck, and K. F. Bard. 1991. Glomerular stereospecific synthesis and hemodynamic actions of 8,9-epoxyeicosatrienoic acid in rat kidney. Am. J. Physiol. 261: F578-F586.
    • (1991) Am. J. Physiol. , vol.261
    • Katoh, T.1    Takahashi, K.2    Capdevila, J.3    Karara, A.4    Falck, J.R.5    Bard, K.F.6
  • 144
    • 0033588034 scopus 로고    scopus 로고
    • Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids
    • Node, K., Y. Huo, X. Ruan, B. Yangf, M. Spiecker, K. Ley, D. Zeldin, and J. K. Liao. 1999. Anti-inflammatory properties of cytochrome P450 epoxygenase-derived eicosanoids. Science. 285: 1276-1279.
    • (1999) Science , vol.285 , pp. 1276-1279
    • Node, K.1    Huo, Y.2    Ruan, X.3    Yangf, B.4    Spiecker, M.5    Ley, K.6    Zeldin, D.7    Liao, J.K.8
  • 145
    • 0030846896 scopus 로고    scopus 로고
    • Nitric oxide and endothelium-derived hyperpolarizing factor: Formation and interactions
    • Bauersachs, J., R. Popp, I. Fleming, and R. Busse. 1997. Nitric oxide and endothelium-derived hyperpolarizing factor: formation and interactions. Prostaglandins Leuko. Essent. Fatty Acids. 57: 439-446.
    • (1997) Prostaglandins Leuko. Essent. Fatty Acids , vol.57 , pp. 439-446
    • Popp, R.1    Fleming, I.2    Busse, R.3
  • 146
    • 0030614947 scopus 로고    scopus 로고
    • NO/PG12-independent vasorelaxation and the cytochrome P450 pathway in rabbit carotid artery
    • Dong, H., G. J. Waldron, D. Galipeau, W. C. Cole, and C. R. Triggle. 1997. NO/PG12-independent vasorelaxation and the cytochrome P450 pathway in rabbit carotid artery. Br. J. Pharmacol. 120: 695-701.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 695-701
    • Dong, H.1    Waldron, G.J.2    Galipeau, D.3    Cole, W.C.4    Triggle, C.R.5
  • 147
    • 0030791845 scopus 로고    scopus 로고
    • Possibleinvolvement of endothelium-derived hyperpolarizing factor in vascular responses of abdominal aorta from pregnant rats
    • Bobadilla, R. A., C. C. Henkel, E. C. Henkel, B. Escalante, and E. Hong. 1997. Possibleinvolvement of endothelium-derived hyperpolarizing factor in vascular responses of abdominal aorta from pregnant rats. Hypertension. 30: 596-602.
    • (1997) Hypertension , vol.30 , pp. 596-602
    • Bobadilla, R.A.1    Henkel, C.C.2    Henkel, E.C.3    Escalante, B.4    Hong, E.5
  • 148
    • 0030788885 scopus 로고    scopus 로고
    • Endothelium-derived hyperpolarizing factor: Characterization as a cytochrome P450 1A-linked metabolite of arachidonic acid in perfused rat mesenteric prearteriolar bed
    • Adeagbo, A. S. 1997. Endothelium-derived hyperpolarizing factor: characterization as a cytochrome P450 1A-linked metabolite of arachidonic acid in perfused rat mesenteric prearteriolar bed. Am. J. Hypertension. 10: 763-771.
    • (1997) Am. J. Hypertension , vol.10 , pp. 763-771
    • Adeagbo, A.S.1
  • 149
    • 0030980377 scopus 로고    scopus 로고
    • Characterization of endothelium-derived relaxing factors released by bradykinin in human resistance arteries
    • Ohlmann, P., M. C. Martinez, F. Schneider, J. C. Stoclet, and R. Andriantsitohaina. 1997. Characterization of endothelium-derived relaxing factors released by bradykinin in human resistance arteries. Br. J. Pharmacol. 121: 657-664.
    • (1997) Br. J. Pharmacol. , vol.121 , pp. 657-664
    • Ohlmann, P.1    Martinez, M.C.2    Schneider, F.3    Stoclet, J.C.4    Andriantsitohaina, R.5
  • 150
    • 0031017779 scopus 로고    scopus 로고
    • Evidence against a role of cytochrome P450-derived arachidonic acid metabolites in endothelium-dependent hyperpolarization by acetylcholine in rat isolated mesenteric artery
    • Fukao, M., Y. Hattori, M. Kanno, I. Sakuma, and A. Kitabatake. 1997. Evidence against a role of cytochrome P450-derived arachidonic acid metabolites in endothelium-dependent hyperpolarization by acetylcholine in rat isolated mesenteric artery. Br. J. Pharmacol. 120: 439-446.
    • (1997) Br. J. Pharmacol. , vol.120 , pp. 439-446
    • Fukao, M.1    Hattori, Y.2    Kanno, M.3    Sakuma, I.4    Kitabatake, A.5
  • 151
    • 0030018728 scopus 로고    scopus 로고
    • Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery
    • Zygmunt, P. M., G. Edwards, A. H. Weston, S. C. Davis, and E. D. Hogestatt. 1996. Effects of cytochrome P450 inhibitors on EDHF-mediated relaxation in the rat hepatic artery. Br. J. Pharmacol. 118: 1147-1152.
    • (1996) Br. J. Pharmacol. , vol.118 , pp. 1147-1152
    • Zygmunt, P.M.1    Edwards, G.2    Weston, A.H.3    Davis, S.C.4    Hogestatt, E.D.5
  • 152
    • 0030068066 scopus 로고    scopus 로고
    • Inhibitors of the cytochrome P450-mono-oxygenase and endothelium-dependent hyperpolarizations in the guinea-pig isolated carotid artery
    • Corriu, C., M. Feletou, E. Canet, and P. M. Vanhoutte. 1996. Inhibitors of the cytochrome P450-mono-oxygenase and endothelium-dependent hyperpolarizations in the guinea-pig isolated carotid artery. Br. J. Pharmacol. 117: 607-610.
    • (1996) Br. J. Pharmacol. , vol.117 , pp. 607-610
    • Corriu, C.1    Feletou, M.2    Canet, E.3    Vanhoutte, P.M.4
  • 153
    • 0032553415 scopus 로고    scopus 로고
    • Identification of the 11,14,15- and 11,12,15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta
    • Pfister, S. L., N. Spitzbarth, K. Nithipatikom, W. S. Edgermond, J. R. Falck, and W. B. Campbell. 1998. Identification of the 11,14,15- and 11,12,15-trihydroxyeicosatrienoic acids as endothelium-derived relaxing factors of rabbit aorta. J. Chem. 273: 30879-30887.
    • (1998) J. Chem. , vol.273 , pp. 30879-30887
    • Pfister, S.L.1    Spitzbarth, N.2    Nithipatikom, K.3    Edgermond, W.S.4    Falck, J.R.5    Campbell, W.B.6
  • 154
    • 0025928864 scopus 로고
    • An epoxygenase metabolite of arachidonic acid 5,6 epoxy-eicosatrienoic acid mediates angiotensin-induced natriuresis in proximal tubular epithelium
    • Romero, M. F., Z. T. Madhun, U. Hopfer, and J. G. Douglas. 1991. An epoxygenase metabolite of arachidonic acid 5,6 epoxy-eicosatrienoic acid mediates angiotensin-induced natriuresis in proximal tubular epithelium. Adv. Prostaglandin, Thromboxane, & Leukotrinie Res. 21A: 205-208.
    • (1991) Adv. Prostaglandin, Thromboxane, & Leukotrinie Res. , vol.21 A , pp. 205-208
    • Romero, M.F.1    Madhun, Z.T.2    Hopfer, U.3    Douglas, J.G.4
  • 155
    • 0029059860 scopus 로고
    • 5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis
    • Sakairi, Y., H. R. Jacobson, T. D. Noland, J. H. Capdevila, J. R. Falck, and M. D. Breyer. 1995. 5,6-EET inhibits ion transport in collecting duct by stimulating endogenous prostaglandin synthesis. Am. J. Physiol. 268: F931-F939.
    • (1995) Am. J. Physiol. , vol.268
    • Sakairi, Y.1    Jacobson, H.R.2    Noland, T.D.3    Capdevila, J.H.4    Falck, J.R.5    Breyer, M.D.6
  • 156
    • 0024804372 scopus 로고
    • Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct
    • Hirt, D.L., J. Capdevila, J. R. Falck, M. D. Breyer, and H. R. Jacobson. 1989. Cytochrome P450 metabolites of arachidonic acid are potent inhibitors of vasopressin action on rabbit cortical collecting duct. J. Clin. Invest. 84: 1805-1812.
    • (1989) J. Clin. Invest. , vol.84 , pp. 1805-1812
    • Hirt, D.L.1    Capdevila, J.2    Falck, J.R.3    Breyer, M.D.4    Jacobson, H.R.5
  • 157
    • 0028271810 scopus 로고
    • Cytochrome P-450 arachidonate metabolites affect ion fluxes in rabbit medullary thick ascending limb
    • Escalante, B., D. Erlij, J. R. Falck, and J. C. McGiff. 1994. Cytochrome P-450 arachidonate metabolites affect ion fluxes in rabbit medullary thick ascending limb. Am. J. Physiol. 266: C1775-1782.
    • (1994) Am. J. Physiol. , vol.266
    • Escalante, B.1    Erlij, D.2    Falck, J.R.3    McGiff, J.C.4
  • 158
    • 0030908812 scopus 로고    scopus 로고
    • P450 arachidonate metabolites mediate bradykinin-dependent inhibition of NaCl transport in the rat thick ascending limb
    • Grider, J. S., J. C. Falcone, E. L. Kilpatrick, C. E. Ott, and B. A. Jackson. 1997. P450 arachidonate metabolites mediate bradykinin-dependent inhibition of NaCl transport in the rat thick ascending limb. Can. J. Physiol. Pharmacol. 75: 91-96.
    • (1997) Can. J. Physiol. Pharmacol. , vol.75 , pp. 91-96
    • Grider, J.S.1    Falcone, J.C.2    Kilpatrick, E.L.3    Ott, C.E.4    Jackson, B.A.5
  • 159
    • 0029976078 scopus 로고    scopus 로고
    • Role of 20-HETE in elevating loop chloride reabsorption in Dahl SS/Jr rats
    • Zou, A. P., H. A. Drummond, and R. J. Roman. 1996. Role of 20-HETE in elevating loop chloride reabsorption in Dahl SS/Jr rats. Hypertension. 27: 631-635.
    • (1996) Hypertension , vol.27 , pp. 631-635
    • Zou, A.P.1    Drummond, H.A.2    Roman, R.J.3
  • 160
    • 0028807418 scopus 로고
    • Effect of arachidonic and on activity of the apical K+ channel in the thick ascending limb of the rat kidney
    • Wang, W., and M. Lu. 1995. Effect of arachidonic and on activity of the apical K+ channel in the thick ascending limb of the rat kidney. J. Gen. Physiol. 106: 727-743.
    • (1995) J. Gen. Physiol. , vol.106 , pp. 727-743
    • Wang, W.1    Lu, M.2
  • 161
    • 0027389456 scopus 로고
    • Activation of K+ channel in vascular smooth muscles by cytochrome P450 metabolites of arachidonic acid
    • Hu, S., and H. S. Kim. 1993. Activation of K+ channel in vascular smooth muscles by cytochrome P450 metabolites of arachidonic acid. Eur. J. Pharmacol. 230: 215-221.
    • (1993) Eur. J. Pharmacol. , vol.230 , pp. 215-221
    • Hu, S.1    Kim, H.S.2
  • 162
    • 0030973315 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein
    • Li, P. L., and W. B. Campbell 1997. Epoxyeicosatrienoic acids activate K+ channels in coronary smooth muscle through a guanine nucleotide binding protein. Circ. Res. 80: 877-884.
    • (1997) Circ. Res. , vol.80 , pp. 877-884
    • Li, P.L.1    Campbell, W.B.2
  • 163
    • 0030786158 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids activate a high-conductance, Ca(2+)-dependent K+ channel on pig coronary artery endothelial cells
    • Baron, A., M. Frieden, and J. L. Beny. 1997. Epoxyeicosatrienoic acids activate a high-conductance, Ca(2+)-dependent K+ channel on pig coronary artery endothelial cells. J. Physiol. 504: 537-543.
    • (1997) J. Physiol. , vol.504 , pp. 537-543
    • Baron, A.1    Frieden, M.2    Beny, J.L.3
  • 166
    • 0028229041 scopus 로고
    • Effects of epoxyeicosatrienoic acids on 86Rb uptake in renal epithelial cells
    • Staudinger, R., B. Escalante, M. L. Schwartzman, and N. G. Abraham. 1994. Effects of epoxyeicosatrienoic acids on 86Rb uptake in renal epithelial cells. J. Cell. Physiol. 160: 69-74.
    • (1994) J. Cell. Physiol. , vol.160 , pp. 69-74
    • Staudinger, R.1    Escalante, B.2    Schwartzman, M.L.3    Abraham, N.G.4
  • 170
    • 0029768938 scopus 로고    scopus 로고
    • Regulation of Na-K-ATPase activity in the proximal tubule: Role of the protein kinase C pathway and of eicosanoids
    • Ominato, M., T. Satoh, and A. I. Katz. 1996. Regulation of Na-K-ATPase activity in the proximal tubule: role of the protein kinase C pathway and of eicosanoids. J. Membr. Biol. 152: 235-243.
    • (1996) J. Membr. Biol. , vol.152 , pp. 235-243
    • Ominato, M.1    Satoh, T.2    Katz, A.I.3
  • 171
    • 0025851750 scopus 로고
    • Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate-early response genes in rat mesangial cells
    • Sellmayer, A., W. M. Uedelhoven, P. C. Weber, and J. V. Bonventre. 1991. Endogenous non-cyclooxygenase metabolites of arachidonic acid modulate growth and mRNA levels of immediate-early response genes in rat mesangial cells. J. Biol. Chem. 266: 3800-3807.
    • (1991) J. Biol. Chem. , vol.266 , pp. 3800-3807
    • Sellmayer, A.1    Uedelhoven, W.M.2    Weber, P.C.3    Bonventre, J.V.4
  • 172
    • 0025183659 scopus 로고
    • Epoxyeicosatreinoic acids are mitogens for rat mesangial cells: Signal transduction pathways
    • Harris, R. C., T. J. Homma, and J. Capdevila. 1990. Epoxyeicosatreinoic acids are mitogens for rat mesangial Cells: signal transduction pathways. J. Cell. Physiol. 144: 429-443.
    • (1990) J. Cell. Physiol. , vol.144 , pp. 429-443
    • Harris, R.C.1    Homma, T.J.2    Capdevila, J.3
  • 174
    • 0032582707 scopus 로고    scopus 로고
    • Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells
    • Chen, J. K., J. R. Falck, R. M. Reddy, J. Capdevila, and R. C. Harris. 1998. Epoxyeicosatrienoic acids and their sulfonimide derivatives stimulate tyrosine phosphorylation and induce mitogenesis in renal epithelial cells. J. Biol. Chem. 273: 29254-29261.
    • (1998) J. Biol. Chem. , vol.273 , pp. 29254-29261
    • Chen, J.K.1    Falck, J.R.2    Reddy, R.M.3    Capdevila, J.4    Harris, R.C.5
  • 175
    • 0028820201 scopus 로고
    • Role of cytochrome P-450 epoxygenase metabolites in EGF signaling in renal proximal tubule
    • Burns, K. D., J. Capdevila, S. Wei, M. D. Breyer, T. Homma, and R. C. Harris. 1995. Role of cytochrome P-450 epoxygenase metabolites in EGF signaling in renal proximal tubule. Am. J. Physiol. 269: C831-C840.
    • (1995) Am. J. Physiol. , vol.269
    • Burns, K.D.1    Capdevila, J.2    Wei, S.3    Breyer, M.D.4    Homma, T.5    Harris, R.C.6
  • 176
    • 0030613773 scopus 로고    scopus 로고
    • 2+ pool-depleted cells is mediated by specific epoxyeicosatrienoic acids derived from arachidonic acid
    • 2+ pool-depleted cells is mediated by specific epoxyeicosatrienoic acids derived from arachidonic acid. J. Biol. Chem. 272: 29546-29553.
    • (1997) J. Biol. Chem. , vol.272 , pp. 29546-29553
    • Graber, M.N.1    Alfonso, A.2    Gill, D.L.3
  • 177
    • 0029177711 scopus 로고
    • 20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule
    • Lin, F. A. Rios, J. R. Falck, Y. Belosludtsev, and M. L. Schwartzman. 1995. 20-Hydroxyeicosatetraenoic acid is formed in response to EGF and is a mitogen in rat proximal tubule. Am. J. Physiol. 269: F806-F816.
    • (1995) Am. J. Physiol. , vol.269
    • Lin, F.1    Rios, A.2    Falck, J.R.3    Belosludtsev, Y.4    Schwartzman, M.L.5
  • 178
    • 0031613013 scopus 로고    scopus 로고
    • Cytochrome P-450 metabolites mediate norepinephrine-induced mitogenic signaling
    • Uddin, M. R., M. M. Muthalif, N. A. Karzoun, I. F. Benter, and K. U. Malik. 1998. Cytochrome P-450 metabolites mediate norepinephrine-induced mitogenic signaling. Hypertension. 31: 242-247.
    • (1998) Hypertension , vol.31 , pp. 242-247
    • Uddin, M.R.1    Muthalif, M.M.2    Karzoun, N.A.3    Benter, I.F.4    Malik, K.U.5
  • 179
    • 0027304834 scopus 로고
    • Cyclooxygenase-derived metabolites of 8,9-epoxyeicosatrienoic acid are potent mitogens for cultured rat glomerular mesangial cells
    • Homma, T., J. Y. Zhang, T. Shimizu, C. Prakash, I. A. Blair, and R. C. Harris. 1993. Cyclooxygenase-derived metabolites of 8,9-epoxyeicosatrienoic acid are potent mitogens for cultured rat glomerular mesangial cells. Biochem. Biophys. Res. Commun. 191: 282-288.
    • (1993) Biochem. Biophys. Res. Commun. , vol.191 , pp. 282-288
    • Homma, T.1    Zhang, J.Y.2    Shimizu, T.3    Prakash, C.4    Blair, I.A.5    Harris, R.C.6
  • 180
    • 0030662206 scopus 로고    scopus 로고
    • Stimulation of prostaglandin G/H synthase-2 expression by arachidonic acid monoxygenase product, 14,15-epoxyeicosatrienoic acid
    • Peri, K. G., D. R. Varma, and S. Chemtob. 1997. Stimulation of prostaglandin G/H synthase-2 expression by arachidonic acid monoxygenase product, 14,15-epoxyeicosatrienoic acid. FEBS Lett. 416: 269-272.
    • (1997) FEBS Lett. , vol.416 , pp. 269-272
    • Peri, K.G.1    Varma, D.R.2    Chemtob, S.3
  • 181
    • 0032489277 scopus 로고    scopus 로고
    • A role for protein kinase C alpha in stimulation of prostaglandin G/H synthase-2 transcription by 14,15-epoxyeicosatrienoic acid
    • Peri, K. G., G. Almazan, D. R. Varma, and S. Chemtob. 1998. A role for protein kinase C alpha in stimulation of prostaglandin G/H synthase-2 transcription by 14,15-epoxyeicosatrienoic acid. Biochem. Biophys. Res. Commun. 244; 96-101.
    • (1998) Biochem. Biophys. Res. Commun. , vol.244 , pp. 96-101
    • Peri, K.G.1    Almazan, G.2    Varma, D.R.3    Chemtob, S.4
  • 182
    • 0033516569 scopus 로고    scopus 로고
    • Peroxisomal and mitochondrial fatty acid β-oxidation in mice nullizygous for both peroxisomal proliferator activated receptor α and peroxisomal fatty acyl-CoA oxidase
    • Hashimoto, T., T. Fujita, N. Usuda, W. Cook, C. Qi, J. M. Peters, F. J. Gonzalez, A. V. Yeldani, S. M. Rao, and J. K. Reddy. 1999. Peroxisomal and mitochondrial fatty acid β-oxidation in mice nullizygous for both peroxisomal proliferator activated receptor α and peroxisomal fatty acyl-CoA oxidase. J. Biol. Chem. 274: 19228-19236.
    • (1999) J. Biol. Chem. , vol.274 , pp. 19228-19236
    • Hashimoto, T.1    Fujita, T.2    Usuda, N.3    Cook, W.4    Qi, C.5    Peters, J.M.6    Gonzalez, F.J.7    Yeldani, A.V.8    Rao, S.M.9    Reddy, K.10
  • 183
    • 0028953133 scopus 로고
    • Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription
    • Aldridge, T. C., J. D. Tugwood, and S. Green. 1995. Identification and characterization of DNA elements implicated in the regulation of CYP4A1 transcription. Biochem. J. 306: 473-479.
    • (1995) Biochem. J. , vol.306 , pp. 473-479
    • Aldridge, T.C.1    Tugwood, J.D.2    Green, S.3
  • 184
    • 0029552026 scopus 로고
    • Translactational induction of CYP4A expression in 10.5-day neonatal rats by the hypolipidemic drug clofibrate
    • Simpson, A. E., W. J. Brammar, M. K. Pratten, and C. R. Elcombe. 1995. Translactational induction of CYP4A expression in 10.5-day neonatal rats by the hypolipidemic drug clofibrate. Biochem. Pharmacol. 50: 2021-2032.
    • (1995) Biochem. Pharmacol. , vol.50 , pp. 2021-2032
    • Simpson, A.E.1    Brammar, W.J.2    Pratten, M.K.3    Elcombe, C.R.4
  • 185
    • 0023573919 scopus 로고
    • Epoxygenase metabolites of arachidonic acid inhibit vasopressin response in toad bladder
    • Schlondorff, D., E. Petty, J. A. Oates, M. Jacoby, and S. D. Levine. 1987. Epoxygenase metabolites of arachidonic acid inhibit vasopressin response in toad bladder. Am. J. Physiol. 53: F464-F470.
    • (1987) Am. J. Physiol. , vol.53
    • Schlondorff, D.1    Petty, E.2    Oates, J.A.3    Jacoby, M.4    Levine, S.D.5
  • 186
    • 0025912065 scopus 로고
    • 2+ influx in human neutrophils is secondary to the emptying of intracellular calcium stores
    • 2+ influx in human neutrophils is secondary to the emptying of intracellular calcium stores. Biochem. J. 277: 73-79.
    • (1991) Biochem. J. , vol.277 , pp. 73-79
    • Montero, M.A.1    Garcia-Sancho, J.2
  • 191
    • 0029560311 scopus 로고
    • Regulation of calcium influx and catecholamine secretion in chromaffin cells by a cytochrome P450 metabolite of arachidonic acid
    • Hildebrandt, E., J. P. Albanesi, J. R. Falck, and W. B. Campbell. 1995. Regulation of calcium influx and catecholamine secretion in chromaffin cells by a cytochrome P450 metabolite of arachidonic acid. J. Lipid Res. 36: 2599-2608.
    • (1995) J. Lipid Res. , vol.36 , pp. 2599-2608
    • Hildebrandt, E.1    Albanesi, J.P.2    Falck, J.R.3    Campbell, W.B.4
  • 192
    • 0025771282 scopus 로고
    • An epoxygenase metabolite of arachidonic acid mediates angiotensin II-induced rises in cytosolic calcium in rabbit proximal tubule epithelial cells
    • Madhun, Z. T., D. A. Goldthwait, D. McKay, U. Hopfer, and J. G. Douglas. 1991. An epoxygenase metabolite of arachidonic acid mediates angiotensin II-induced rises in cytosolic calcium in rabbit proximal tubule epithelial cells. J. Clin. Invest. 88: 456-461.
    • (1991) J. Clin. Invest. , vol.88 , pp. 456-461
    • Madhun, Z.T.1    Goldthwait, D.A.2    McKay, D.3    Hopfer, U.4    Douglas, J.G.5
  • 194
    • 0026989776 scopus 로고
    • 14(R), 15(S)-epoxyeicosatrienoic acid (14(R), 15(S)-EET) receptor in guinea pig mononuclear cell membranes
    • Wong, P. Y., K. T. Lin, Y. T. Yan, D. Ahern, J. Iles, S. Y. Shen, R. K. Bhatt, and J. R. Falck. 1993. 14(R), 15(S)-epoxyeicosatrienoic acid (14(R), 15(S)-EET) receptor in guinea pig mononuclear cell membranes. J. Lipid Mediat. 6: 199-208.
    • (1993) J. Lipid Mediat. , vol.6 , pp. 199-208
    • Wong, P.Y.1    Lin, K.T.2    Yan, Y.T.3    Ahern, D.4    Iles, J.5    Shen, S.Y.6    Bhatt, R.K.7    Falck, J.R.8
  • 195
    • 0030961344 scopus 로고    scopus 로고
    • High affinity binding sites for [12(R)-HETrE] in microvessel endothelial cells
    • Stoltz, R. A., and M. L. Schwartzman. 1997. High affinity binding sites for [12(R)-HETrE] in microvessel endothelial cells. J. Ocular Pharmacol. Ther. 13: 191-199.
    • (1997) J. Ocular Pharmacol. Ther. , vol.13 , pp. 191-199
    • Stoltz, R.A.1    Schwartzman, M.L.2
  • 196
    • 0026586466 scopus 로고
    • Epoxyeicosatrienoic acid stimulates ADP-ribosylation of a 52 kDa protein in rat liver cytosol
    • Seki, K., A. Hirai, M. Noda, Y. Tamura, I. Kato, and S. Yoshida. 1992. Epoxyeicosatrienoic acid stimulates ADP-ribosylation of a 52 kDa protein in rat liver cytosol. Biochem. J. 281: 185-190.
    • (1992) Biochem. J. , vol.281 , pp. 185-190
    • Seki, K.1    Hirai, A.2    Noda, M.3    Tamura, Y.4    Kato, I.5    Yoshida, S.6
  • 197
    • 0031194598 scopus 로고    scopus 로고
    • Post-receptor signal transduction and regulation of 14(R), 15(S)-epoxyeicosatrienoic acid (14,15-EET) binding in U-937 cells
    • Wong, P. Y. K., P. S. Lai, S. Y. Shen, Y. Y. Belosludtsev, and J. R. Falck. 1997. Post-receptor signal transduction and regulation of 14(R), 15(S)-epoxyeicosatrienoic acid (14,15-EET) binding in U-937 cells. J. Lipid Mediat. Cell Signal. 16: 155-169.
    • (1997) J. Lipid Mediat. Cell Signal , vol.16 , pp. 155-169
    • Wong, P.Y.K.1    Lai, P.S.2    Shen, S.Y.3    Belosludtsev, Y.Y.4    Falck, J.R.5
  • 199
    • 0026596934 scopus 로고
    • Renal cytochrome P-450-arachidonic acid metabolism: Localization and hormonal regulation in SHR
    • Omata, K., N. G. Abraham, and M. L. Schwartzman. 1992. Renal cytochrome P-450-arachidonic acid metabolism: localization and hormonal regulation in SHR. Am. J. Physiol. 262: F591-F599.
    • (1992) Am. J. Physiol. , vol.262
    • Omata, K.1    Abraham, N.G.2    Schwartzman, M.L.3
  • 200
    • 0033582481 scopus 로고    scopus 로고
    • Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor
    • Chen, J. K., D. W. Wang, J. R. Falck, J. Capdevila, and R. C. Harris. 1999. Transfection of an active cytochrome P450 arachidonic acid epoxygenase indicates that 14,15-epoxyeicosatrienoic acid functions as an intracellular second messenger in response to epidermal growth factor. J. Biol. Chem. 274: 4764-4769.
    • (1999) J. Biol. Chem. , vol.274 , pp. 4764-4769
    • Chen, J.K.1    Wang, D.W.2    Falck, J.R.3    Capdevila, J.4    Harris, R.C.5
  • 201
    • 0029904987 scopus 로고    scopus 로고
    • Signaling pathways in the biphasic effect of angiostensin II on apical Na/H antiport activity in proximal tubule
    • Houillier, P., R. Chamrey, J. M. Achard, M. Froissart, J. Poggioli, and M. Paillard. 1996. Signaling pathways in the biphasic effect of angiostensin II on apical Na/H antiport activity in proximal tubule. Kidney Int. 50: 1496-1505.
    • (1996) Kidney Int. , vol.50 , pp. 1496-1505
    • Houillier, P.1    Chamrey, R.2    Achard, J.M.3    Froissart, M.4    Poggioli, J.5    Paillard, M.6
  • 202
    • 0028204392 scopus 로고
    • Parathyroid hormone inhibits Na(+)-K(+)-ATPase through a cytochrome P-450 pathway
    • Ribeiro, C. M., G. R. Dubay, J. R. Falck, and L. J. Mandel. 1994. Parathyroid hormone inhibits Na(+)-K(+)-ATPase through a cytochrome P-450 pathway. Am. J. Physiol. 266: F497-F505.
    • (1994) Am. J. Physiol. , vol.266
    • Ribeiro, C.M.1    Dubay, G.R.2    Falck, J.R.3    Mandel, L.J.4
  • 203
    • 0031593394 scopus 로고    scopus 로고
    • Renal functtional effects of endothelins: Dependency on cytochrome P450-derived arachidonate metabolites
    • Oyekan, A. O., K. McAward, and J. C. McGiff. 1998. Renal functtional effects of endothelins: dependency on cytochrome P450-derived arachidonate metabolites. Biol. Res. 31: 209-215.
    • (1998) Biol. Res. , vol.31 , pp. 209-215
    • Oyekan, A.O.1    McAward, K.2    McGiff, J.C.3
  • 204
    • 0032514708 scopus 로고    scopus 로고
    • 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells
    • Muthalif, M. M., I. F. Benter, N. Karzoun, S. Fatima, J. Harper, M. R. Uddin, and K. U. Malik. 1998. 20-Hydroxyeicosatetraenoic acid mediates calcium/calmodulin-dependent protein kinase II-induced mitogen-activated protein kinase activation in vascular smooth muscle cells. Proc. Natl. Acad. Sci. USA. 95: 12701-12706.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 12701-12706
    • Muthalif, M.M.1    Benter, I.F.2    Karzoun, N.3    Fatima, S.4    Harper, J.5    Uddin, M.R.6    Malik, K.U.7
  • 205
    • 0031963859 scopus 로고    scopus 로고
    • Functional hyperemia in the brain: Hypothesis for astrocyte-derived vasodilator metabolites
    • Harder, D. R., N. J. Alkayed, A. R. Lange, D. Gebremedhin, and R. J. Roman. 1998. Functional hyperemia in the brain: hypothesis for astrocyte-derived vasodilator metabolites. Stroke. 29: 229-234.
    • (1998) Stroke , vol.29 , pp. 229-234
    • Harder, D.R.1    Alkayed, N.J.2    Lange, A.R.3    Gebremedhin, D.4    Roman, R.J.5
  • 207
    • 0025963568 scopus 로고
    • Isolation of preferentially expressed genes in the kidneys of hypertensive rats
    • Iwai, N., and T. Inagani. 1991. Isolation of preferentially expressed genes in the kidneys of hypertensive rats. Hypertension 17: 161-169.
    • (1991) Hypertension , vol.17 , pp. 161-169
    • Iwai, N.1    Inagani, T.2
  • 208
    • 0031844011 scopus 로고    scopus 로고
    • Inhibition of renal AA w-hydroxylase activity with ABT reduced blood pressure in the SHR
    • Su, P., K. M. Kaushal, and D. L. Kroetz. 1998. Inhibition of renal AA w-hydroxylase activity with ABT reduced blood pressure in the SHR. Am. J. Physiol. 275: R426-R438.
    • (1998) Am. J. Physiol. , vol.275
    • Su, P.1    Kaushal, K.M.2    Kroetz, D.L.3
  • 209
    • 0032995361 scopus 로고    scopus 로고
    • Contribution of cytochrome P450 4A1 and 4A2 to vascular 20-hydroxyeicosatetraenoic acid synthesis in rat kidneys
    • Wang, M. H., H. Guan, X. Nguyen, B. A. Zand, A. Nasjlettii and M. Laniado-Schwartzman. 1999. Contribution of cytochrome P450 4A1 and 4A2 to vascular 20-hydroxyeicosatetraenoic acid synthesis in rat kidneys. Am. J. Physiol. 276: F246-F253.
    • (1999) Am. J. Physiol. , vol.276
    • Wang, M.H.1    Guan, H.2    Nguyen, X.3    Zand, B.A.4    Nasjlettii, A.5    Laniado-Schwartzman, M.6
  • 210
    • 0020435968 scopus 로고
    • Dahl salt-susceptible and Dahl salt-resistant rats. A review
    • Rapp, J. P. 1982. Dahl salt-susceptible and Dahl salt-resistant rats. A review. Hypertension. 4: 753-763.
    • (1982) Hypertension , vol.4 , pp. 753-763
    • Rapp, J.P.1
  • 211
    • 0031025761 scopus 로고    scopus 로고
    • Inhibition of renal outer medullary 20-HETE production produces hypertension in Lewis rats
    • Stec, D. E., D. L. Mattson, and R. J. Roman. 1997. Inhibition of renal outer medullary 20-HETE production produces hypertension in Lewis rats. Hypertension. 29: 315-319.
    • (1997) Hypertension , vol.29 , pp. 315-319
    • Stec, D.E.1    Mattson, D.L.2    Roman, R.J.3
  • 212
    • 0027978092 scopus 로고
    • Altered renal P-450 metabolism of AA in Dahl salt-sensitive rats
    • Ma, Y. H., M. L. Schwartzman, and R. J. Roman. 1994. Altered renal P-450 metabolism of AA in Dahl salt-sensitive rats. Am. J. Physiol. 267: R579-R589.
    • (1994) Am. J. Physiol. , vol.267
    • Ma, Y.H.1    Schwartzman, M.L.2    Roman, R.J.3
  • 213
    • 0029976078 scopus 로고    scopus 로고
    • Role of 20-HETE in elevating loop chloride reabsorption in Dahl SS/Jr. Rats
    • Zhou, A. P., H. A. Drummond, and R. J. Roman. 1996. Role of 20-HETE in elevating loop chloride reabsorption in Dahl SS/Jr. rats. Hypertension. 27: 631-635.
    • (1996) Hypertension , vol.27 , pp. 631-635
    • Zhou, A.P.1    Drummond, H.A.2    Roman, R.J.3
  • 214
    • 0030007897 scopus 로고    scopus 로고
    • Cytochrome P4504A genotype cosegregates with hypertension in Dahl S rats
    • Stec, D. E., A. Y. Deng, J. P. Rapp, and R. J. Roman. 1996. Cytochrome P4504A genotype cosegregates with hypertension in Dahl S rats. Hypertension. 27: 564-568.
    • (1996) Hypertension , vol.27 , pp. 564-568
    • Stec, D.E.1    Deng, A.Y.2    Rapp, J.P.3    Roman, R.J.4
  • 215
    • 0027996820 scopus 로고
    • Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet
    • Makita, K., K. Takahashi, A. Karara, H. R. Jacobson, J. R. Falck, and J. H. Capdevila. 1994. Experimental and/or genetically controlled alterations of the renal microsomal cytochrome P450 epoxygenase induce hypertension in rats fed a high salt diet. J. Clin. Invest. 94: 2414-2420.
    • (1994) J. Clin. Invest. , vol.94 , pp. 2414-2420
    • Makita, K.1    Takahashi, K.2    Karara, A.3    Jacobson, H.R.4    Falck, J.R.5    Capdevila, J.H.6
  • 216
    • 0032747358 scopus 로고    scopus 로고
    • Renal cytochrome P450 ω-hydroxylase and epoxygenase activity are differentially modified by nitric oxide and sodium chloride
    • Oyekan, A. O., T. Youseff, D. Fulton, J. Quilley, and J. C. McGiff. 1999. Renal cytochrome P450 ω-hydroxylase and epoxygenase activity are differentially modified by nitric oxide and sodium chloride. J. Clin. Invest. 104: 1131-1137.
    • (1999) J. Clin. Invest. , vol.104 , pp. 1131-1137
    • Oyekan, A.O.1    Youseff, T.2    Fulton, D.3    Quilley, J.4    McGiff, J.C.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.