Elucidation of the genetic basis of the common 'intermediate metabolizer' phenotype for drug oxidation by CYP2D6

Pharmacogenetics

Volumn 10, Issue 7, 2000, Pages 577-581

  Raimundo, S ^a   Fischer, J ^a   Eichelbaum, M ^a   Griese, E U ^a   Schwab, M ^a   Zanger, U M ^a  

^a DR MARGARETE FISCHER BOSCH INSTITUTE OF CLINICAL PHARMACOLOGY   (Germany)

Author keywords

CYP2D6; Debrisoquine sparteine polymorphism; Intermediate metabolizer; Promoter mutation

Indexed keywords

DEBRISOQUINE 4 HYDROXYLASE; SPARTEINE;

ALLELE; ARTICLE; CAUCASIAN; CONTROLLED STUDY; DNA FLANKING REGION; DRUG OXIDATION; ENZYME ACTIVITY; GENE MUTATION; GENETIC VARIABILITY; GENOTYPE; HUMAN; PHARMACOGENETICS; PHENOTYPE; PRIORITY JOURNAL; URINARY EXCRETION;

BASE SEQUENCE; CYTOCHROME P-450 CYP2D6; DNA PRIMERS; FEMALE; GENOTYPE; HUMAN; MALE; MUTATION; OXIDATION-REDUCTION; PEDIGREE; PHENOTYPE; SPARTEINE; SUPPORT, NON-U.S. GOV'T;

EID: 0033790979     PISSN: 0960314X     EISSN: None     Source Type: Journal    
DOI: 10.1097/00008571-200010000-00001     Document Type: Article

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