메뉴 건너뛰기




Volumn 12, Issue 5, 1998, Pages 553-558

Cytochrome P450 2E1 activity in diabetic and obese patients as assessed by chlorzoxazone hydroxylation

Author keywords

Chlorzoxazone; Cytochrome P450 2E1; Diabetes; Obesity

Indexed keywords

3 HYDROXYBUTYRIC ACID; ANESTHETIC AGENT; BIGUANIDE; CHLORZOXAZONE; CHOLESTEROL; CYTOCHROME P450 2E1; CYTOCHROME P450 ISOENZYME; ENFLURANE; FRUCTOSAMINE; GLYCOSYLATED HEMOGLOBIN; INSULIN; KETONE; PARACETAMOL; PHENAZONE; SEVOFLURANE; SULFONYLUREA; TRIACYLGLYCEROL; UNCLASSIFIED DRUG;

EID: 0032437172     PISSN: 07673981     EISSN: None     Source Type: Journal    
DOI: 10.1111/j.1472-8206.1998.tb00985.x     Document Type: Article
Times cited : (106)

References (40)
  • 1
    • 0023736170 scopus 로고
    • Role of ketone bodies in the diabetes-induced changes in hepatic mixed-function oxidase activities
    • Barnett CR, Flatt PR, Ioannides C. Role of ketone bodies in the diabetes-induced changes in hepatic mixed-function oxidase activities. Bioch Biophys Acta 1988 ; 967 : 250-4
    • (1988) Bioch Biophys Acta , vol.967 , pp. 250-254
    • Barnett, C.R.1    Flatt, P.R.2    Ioannides, C.3
  • 2
    • 0026612117 scopus 로고
    • Cytochrome-dependent mixed-function oxidase and glutathion S-transferase activities in spontaneous obesity-diabetes
    • Barnett CR, Abbott RA, Bailey CJ, Flatt PR, Ioannides C. Cytochrome-dependent mixed-function oxidase and glutathion S-transferase activities in spontaneous obesity-diabetes. Biochem Pharmacol 1992 ; 43 : 1868-71
    • (1992) Biochem Pharmacol , vol.43 , pp. 1868-1871
    • Barnett, C.R.1    Abbott, R.A.2    Bailey, C.J.3    Flatt, P.R.4    Ioannides, C.5
  • 3
    • 0028408181 scopus 로고
    • Modulation of the rat hepatic cytochrome P450 composition by long-term streptozotocininduced insulin-dependent diabetes
    • Barnett C, Flatt PR, Ioannides C. Modulation of the rat hepatic cytochrome P450 composition by long-term streptozotocininduced insulin-dependent diabetes. J Biochem Toxicol 1994 ; 9 : 63-9
    • (1994) J Biochem Toxicol , vol.9 , pp. 63-69
    • Barnett, C.1    Flatt, P.R.2    Ioannides, C.3
  • 4
    • 0025732948 scopus 로고
    • Role of oxidative stress in development of complications in diabetes
    • Baynes JW. Role of oxidative stress in development of complications in diabetes. Diabetes 1991 ; 40 : 405-12
    • (1991) Diabetes , vol.40 , pp. 405-412
    • Baynes, J.W.1
  • 6
    • 0023629587 scopus 로고
    • Influence of obesity on drug disposition
    • Blouin RA, Kolpek JH, Mann HJ. Influence of obesity on drug disposition. Clin Pharm 1987 ; 6 : 706-14
    • (1987) Clin Pharm , vol.6 , pp. 706-714
    • Blouin, R.A.1    Kolpek, J.H.2    Mann, H.J.3
  • 8
    • 0030050657 scopus 로고    scopus 로고
    • Induction and suppression of renal and hepatic cytochrome P450-dependent monooxygenases by acute and chronic streptozotocin diabetes in hamsters
    • Chen TL, Chen SH, Tai TY, Chao CC, Park SS, Guengerich FP, Ueng TH. Induction and suppression of renal and hepatic cytochrome P450-dependent monooxygenases by acute and chronic streptozotocin diabetes in hamsters. Arch Toxicol 1996 ; 70 : 202-8
    • (1996) Arch Toxicol , vol.70 , pp. 202-208
    • Chen, T.L.1    Chen, S.H.2    Tai, T.Y.3    Chao, C.C.4    Park, S.S.5    Guengerich, F.P.6    Ueng, T.H.7
  • 9
    • 0028964669 scopus 로고
    • Insulin down-regulates cytochrome P450 2B and 2E expression at the post-transcriptional level in the rat hepatoma cell line
    • De Waziers I, Garlatti M, Bouguet J, Beaune PH, Barouki R. Insulin down-regulates cytochrome P450 2B and 2E expression at the post-transcriptional level in the rat hepatoma cell line. Mol Pharmacol 1995 ; 47 : 474-9
    • (1995) Mol Pharmacol , vol.47 , pp. 474-479
    • De Waziers, I.1    Garlatti, M.2    Bouguet, J.3    Beaune, P.H.4    Barouki, R.5
  • 11
    • 0024546914 scopus 로고
    • Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450
    • Ekström G, Ingelman-Sundberg M. Rat liver microsomal NADPH-supported oxidase activity and lipid peroxidation dependent on ethanol-inducible cytochrome P450. Biochem Pharmacol 1989 ; 38 : 1313-8
    • (1989) Biochem Pharmacol , vol.38 , pp. 1313-1318
    • Ekström, G.1    Ingelman-Sundberg, M.2
  • 12
    • 0028304678 scopus 로고
    • Assessment of cytochrome P4502E1 induction in alcoholic patients by chlorzoxazone pharmacokinetics
    • Girre C, Lucas D, Hispard E, Ménez C, Dally S, Ménez J-F. Assessment of cytochrome P4502E1 induction in alcoholic patients by chlorzoxazone pharmacokinetics. Biochem Pharmacol 1994 ; 47 : 1503-8
    • (1994) Biochem Pharmacol , vol.47 , pp. 1503-1508
    • Girre, C.1    Lucas, D.2    Hispard, E.3    Ménez, C.4    Dally, S.5    Ménez, J.-F.6
  • 13
    • 0025227918 scopus 로고
    • Hepatic drug metabolism is increased in poorly controlled insulin-dependent diabetes mellitus
    • Goldstein S, Simpson A, Saenger P. Hepatic drug metabolism is increased in poorly controlled insulin-dependent diabetes mellitus. Acta Endocrinol 1990 ; 123 : 550-6
    • (1990) Acta Endocrinol , vol.123 , pp. 550-556
    • Goldstein, S.1    Simpson, A.2    Saenger, P.3
  • 14
    • 0028272001 scopus 로고
    • Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins
    • Gonzales FJ, Gelboin HV. Role of human cytochromes P450 in the metabolic activation of chemical carcinogens and toxins. Drug Metab Rev 1994 ; 26 : 165-83
    • (1994) Drug Metab Rev , vol.26 , pp. 165-183
    • Gonzales, F.J.1    Gelboin, H.V.2
  • 15
    • 0027364633 scopus 로고
    • Serum inorganic fluoride levels in mildly obese patients during and after sevoflurane anesthesia
    • Higuchi H, Sato H, Arimura S. Serum inorganic fluoride levels in mildly obese patients during and after sevoflurane anesthesia. Anesth Analg 1993 ; 77 : 1018-21
    • (1993) Anesth Analg , vol.77 , pp. 1018-1021
    • Higuchi, H.1    Sato, H.2    Arimura, S.3
  • 16
    • 0029033232 scopus 로고
    • Renal function in patients with high fluoride concentrations after prolonged sevoflurane anesthesia
    • Higuchi H, Sumikura H, Sumita S. Renal function in patients with high fluoride concentrations after prolonged sevoflurane anesthesia. Anesthesiology 1995 ; 83 : 449-58
    • (1995) Anesthesiology , vol.83 , pp. 449-458
    • Higuchi, H.1    Sumikura, H.2    Sumita, S.3
  • 17
    • 0023900010 scopus 로고
    • Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: Regulation and characteristics of enzymes belonging to the II B and II E gene subfamilies
    • Johansson I, Ekström G, Schölte B, Puzycki D, Jörnvall H, Ingelman-Sundberg M. Ethanol-, fasting-, and acetone-inducible cytochromes P-450 in rat liver: Regulation and characteristics of enzymes belonging to the II B and II E gene subfamilies. Biochemistry 1988 ; 27 : 1925-34
    • (1988) Biochemistry , vol.27 , pp. 1925-1934
    • Johansson, I.1    Ekström, G.2    Schölte, B.3    Puzycki, D.4    Jörnvall, H.5    Ingelman-Sundberg, M.6
  • 18
    • 0028843993 scopus 로고
    • Biotransformation of sevoflurane
    • Karash ED. Biotransformation of sevoflurane. Anesth Analg 1995 ; 81 : S27-38
    • (1995) Anesth Analg , vol.81
    • Karash, E.D.1
  • 19
    • 0029035739 scopus 로고
    • Interindividual variability in chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphism
    • Kim RB, O'Shea D, Wilkinson GR. Interindividual variability in chlorzoxazone 6-hydroxylation in men and women and its relationship to CYP2E1 genetic polymorphism. Clin Pharmacol Ther 1995 ; 57 : 645-55
    • (1995) Clin Pharmacol Ther , vol.57 , pp. 645-655
    • Kim, R.B.1    O'Shea, D.2    Wilkinson, G.R.3
  • 20
    • 0022827585 scopus 로고
    • Ethanol oxidation and toxicity: Role of alcohol P-450 oxygenase
    • Koop DR, Coon MJ. Ethanol oxidation and toxicity: role of alcohol P-450 oxygenase. Alcoholism Clin Exp Res 1986 ; 10 : S44-9
    • (1986) Alcoholism Clin Exp Res , vol.10
    • Koop, D.R.1    Coon, M.J.2
  • 21
    • 0010584904 scopus 로고    scopus 로고
    • Influence of diet on liver volume and cytochrome P 450 (CYP) activities in human non-alcoholic fatty liver
    • Leclerq I, Horsmans Y, Dasager JP, Pauwels S, Geubel AP. Influence of diet on liver volume and cytochrome P 450 (CYP) activities in human non-alcoholic fatty liver (Abstract). Hepatology 1996 ; 24 : 311A
    • (1996) Hepatology , vol.24
    • Leclerq, I.1    Horsmans, Y.2    Dasager, J.P.3    Pauwels, S.4    Geubel, A.P.5
  • 22
    • 0030935567 scopus 로고    scopus 로고
    • Cytochrome P-4502E1: Its physiological and pathological role
    • Lieber CS. Cytochrome P-4502E1: its physiological and pathological role. Physiol Rev 1997 ; 77 : 517-44
    • (1997) Physiol Rev , vol.77 , pp. 517-544
    • Lieber, C.S.1
  • 23
    • 0027332414 scopus 로고
    • High-performance liquid chromatographic determination of chlorzoxazone and 6-hydroxychlorzoxazone in serum and urine: A tool for indirect evaluation of cytochrome P450 2E1 activity in humans
    • Lucas D, Berthou F, Girre C, Poitrenaud F, Ménez J-F. High-Performance Liquid Chromatographic determination of chlorzoxazone and 6-hydroxychlorzoxazone in serum and urine: a tool for indirect evaluation of cytochrome P450 2E1 activity in humans. J Chromatogr Biomed Appl 1993 ; 622 : 79-86
    • (1993) J Chromatogr Biomed Appl , vol.622 , pp. 79-86
    • Lucas, D.1    Berthou, F.2    Girre, C.3    Poitrenaud, F.4    Ménez, J.-F.5
  • 24
    • 0028915241 scopus 로고
    • Decrease in cytochrome P4502E1 as assessed by the rate of chlorzoxazone hydroxylation in alcoholics during the withdrawal phase
    • Lucas D, Ménez C, Girre C, Bodénez P, Hispard E, Ménez J-F. Decrease in cytochrome P4502E1 as assessed by the rate of chlorzoxazone hydroxylation in alcoholics during the withdrawal phase. Alcoholism Clin Exp Res 1995 ; 19 : 362-6
    • (1995) Alcoholism Clin Exp Res , vol.19 , pp. 362-366
    • Lucas, D.1    Ménez, C.2    Girre, C.3    Bodénez, P.4    Hispard, E.5    Ménez, J.-F.6
  • 26
    • 0029775813 scopus 로고    scopus 로고
    • Chlorzoxazone: In vitro and in vivo substrate probe for liver CYP2E1
    • Lucas D, Berthou F, Ménez J-F. Chlorzoxazone: In vitro and in vivo substrate probe for liver CYP2E1. Meth Enzymol 1996 ; 272 : 115-23
    • (1996) Meth Enzymol , vol.272 , pp. 115-123
    • Lucas, D.1    Berthou, F.2    Ménez, J.-F.3
  • 28
    • 0028037221 scopus 로고
    • Effect of fasting and obesity in humans on the 6-hydoxylation of chlorzoxazone: A putative probe of CYP2E1 activity
    • O'Shea D, Davis SN, Kim RB, Wilkinson GR. Effect of fasting and obesity in humans on the 6-hydoxylation of chlorzoxazone: a putative probe of CYP2E1 activity. Clin Pharmacol Ther 1994 ; 56 : 359-67
    • (1994) Clin Pharmacol Ther , vol.56 , pp. 359-367
    • O'Shea, D.1    Davis, S.N.2    Kim, R.B.3    Wilkinson, G.R.4
  • 31
    • 0028172842 scopus 로고
    • Cytochrome P450 changes in rats with streptozotocin-induced diabetes
    • Shimojo N. Cytochrome P450 changes in rats with streptozotocin-induced diabetes, Int J Biochem 1994 ; 26 : 1261-8
    • (1994) Int J Biochem , vol.26 , pp. 1261-1268
    • Shimojo, N.1
  • 33
    • 0025074850 scopus 로고
    • Cytochrome P450 IIE1 is elevated in lymphocytes from poorly controlled insulin-dependent diabetics
    • Song BF, Veech RL, Saenger P. Cytochrome P450 IIE1 is elevated in lymphocytes from poorly controlled insulin-dependent diabetics. J Clin Endocrinol Metab 1990 ; 71 : 1036-40
    • (1990) J Clin Endocrinol Metab , vol.71 , pp. 1036-1040
    • Song, B.F.1    Veech, R.L.2    Saenger, P.3
  • 34
    • 0001484838 scopus 로고
    • Gene structure and mutiple regulations of the ethanol-inducible cytochrome P4502E1 (CYP2E1) subfamily
    • Watson R, Ed. Towota, NJ: Humana press Inc
    • Song BJ. Gene structure and mutiple regulations of the ethanol-inducible cytochrome P4502E1 (CYP2E1) subfamily. In: Watson R, Ed. Drug and Alcohol Abuse Reviews, Vol 6: Alcohol and Hormones. Towota, NJ: Humana press Inc; 1995. p 177-92
    • (1995) Drug and Alcohol Abuse Reviews, Vol 6: Alcohol and Hormones , vol.6 , pp. 177-192
    • Song, B.J.1
  • 35
    • 0021266980 scopus 로고
    • Hepatic microsomal enzyme activity in patients with non-insulin dependent diabetes mellitus NIDDM and its clinical significance
    • Sotaniemi EA, Arranto AJ, Salmele PI, Stengard JH, Pelkonen RO. Hepatic microsomal enzyme activity in patients with non-insulin dependent diabetes mellitus (NIDDM and its clinical significance. Acta Endocrinol 1984 ; 262 (suppl) : 125-9
    • (1984) Acta Endocrinol , vol.262 , Issue.SUPPL. , pp. 125-129
    • Sotaniemi, E.A.1    Arranto, A.J.2    Salmele, P.I.3    Stengard, J.H.4    Pelkonen, R.O.5
  • 37
    • 0031962151 scopus 로고    scopus 로고
    • Hepatic cytochrome P450 2E1 is increased in patients with non-alcoholic steatohepatitis
    • Weltman MD, Farrell GC, Hall P, Ingelman-Sundberg M, Liddie C. Hepatic cytochrome P450 2E1 is increased in patients with non-alcoholic steatohepatitis. Hepatology 1998 ; 27 : 128-33
    • (1998) Hepatology , vol.27 , pp. 128-133
    • Weltman, M.D.1    Farrell, G.C.2    Hall, P.3    Ingelman-Sundberg, M.4    Liddie, C.5
  • 38
    • 0025773608 scopus 로고
    • Regulation of hepatic microsomal cytochrome P450IIE1 level by dietary lipids and carbohydrates in rats
    • Yoo JSH, Ning SM, Pantuck CB, Pantuck EJ, Yang CS. Regulation of hepatic microsomal cytochrome P450IIE1 level by dietary lipids and carbohydrates in rats. J Nutr 1991 ; 121 : 959-61
    • (1991) J Nutr , vol.121 , pp. 959-961
    • Yoo, J.S.H.1    Ning, S.M.2    Pantuck, C.B.3    Pantuck, E.J.4    Yang, C.S.5
  • 39
    • 0026523825 scopus 로고
    • Pretranslational activation of cytochrome P450IIE during ketosis induced by high fat diet
    • Yun YP, Casazza JP, Sohn DH, Veech RL, Song BJ. Pretranslational activation of cytochrome P450IIE during ketosis induced by high fat diet. Mol Pharmacol 1992 ; 41 : 474-9
    • (1992) Mol Pharmacol , vol.41 , pp. 474-479
    • Yun, Y.P.1    Casazza, J.P.2    Sohn, D.H.3    Veech, R.L.4    Song, B.J.5
  • 40
    • 0031568250 scopus 로고    scopus 로고
    • Effects of fatty acids and ketone bodies on cytochromes P450 2B, 4A, and 2E1 expression in primary cultured rat hepatocytes
    • Zangar RC, Novack RF. Effects of fatty acids and ketone bodies on cytochromes P450 2B, 4A, and 2E1 expression in primary cultured rat hepatocytes. Arch Biochem Biophys 1997 ; 337 : 217-4
    • (1997) Arch Biochem Biophys , vol.337 , pp. 217-224
    • Zangar, R.C.1    Novack, R.F.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.