메뉴 건너뛰기




Volumn , Issue , 2016, Pages 481-534

Improving bioavailability of nutraceuticals by nanoemulsification

Author keywords

bioaccessibility; bioavailability; curcumin; lutein; nanoemulsion; nutraceuticals; resveratrol

Indexed keywords


EID: 85048458204     PISSN: None     EISSN: None     Source Type: Book    
DOI: 10.1016/B978-0-12-804305-9.00013-0     Document Type: Chapter
Times cited : (10)

References (285)
  • 1
    • 84876188878 scopus 로고    scopus 로고
    • Dietary sources of lutein and zeaxanthin carotenoids and their role in eye health
    • E.-S.M. Abdel-Aal El-S.M., H. Akhtar, K. Zaheer and R. Ali (2013) Dietary sources of lutein and zeaxanthin carotenoids and their role in eye health. Nutrients 5 1169-1185.
    • (2013) Nutrients , vol.5 , pp. 1169-1185
    • Abdel-Aal, E.-S.M.1    Akhtar, H.2    Zaheer, K.3    Ali, R.4
  • 2
    • 84978897668 scopus 로고    scopus 로고
    • Eugenol oil nanoemulsion: antifungal activity against Fusarium oxysporum f. sp. vasinfectum and phytotoxicity on cottonseeds
    • K.A. Abd-Elsalam and A.R. Khokhlov (2015) Eugenol oil nanoemulsion: antifungal activity against Fusarium oxysporum f. sp. vasinfectum and phytotoxicity on cottonseeds. App. Nanosci. 5 255-265.
    • (2015) App. Nanosci. , vol.5 , pp. 255-265
    • Abd-Elsalam, K.A.1    Khokhlov, A.R.2
  • 3
    • 84908388192 scopus 로고    scopus 로고
    • Codelivery of hydrophobic curcumin and hydrophilic catechin by a water-in-oil-in-water double emulsion
    • N.P. Aditya, S. Aditya, H. Yang, H.W. Kim, S.O. Park and S. Ko (2015) Codelivery of hydrophobic curcumin and hydrophilic catechin by a water-in-oil-in-water double emulsion. Food Chem. 173 7-13.
    • (2015) Food Chem. , vol.173 , pp. 7-13
    • Aditya, N.P.1    Aditya, S.2    Yang, H.3    Kim, H.W.4    Park, S.O.5    Ko, S.6
  • 5
    • 77649274672 scopus 로고    scopus 로고
    • Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat
    • R. Agrawal, B. Mishra, E. Tyagi, C. Nath and R. Shukla (2010) Effect of curcumin on brain insulin receptors and memory functions in STZ (ICV) induced dementia model of rat. Pharmacol. Res. 61 247-252.
    • (2010) Pharmacol. Res. , vol.61 , pp. 247-252
    • Agrawal, R.1    Mishra, B.2    Tyagi, E.3    Nath, C.4    Shukla, R.5
  • 6
    • 84855715840 scopus 로고    scopus 로고
    • Nanoemulsion- and emulsion-based delivery systems for curcumin: encapsulation and release properties
    • K. Ahmed, Y. Li, D.J. McClements and H. Xiao (2012) Nanoemulsion- and emulsion-based delivery systems for curcumin: encapsulation and release properties. Food Chem. 132 799-807.
    • (2012) Food Chem. , vol.132 , pp. 799-807
    • Ahmed, K.1    Li, Y.2    McClements, D.J.3    Xiao, H.4
  • 7
    • 0032512698 scopus 로고    scopus 로고
    • Strand scission in DNA induced by curcumin in the presence of Cu(II)
    • H. Ahsan and S.M. Hadi (1998) Strand scission in DNA induced by curcumin in the presence of Cu(II). Cancer Lett. 124 23-30.
    • (1998) Cancer Lett. , vol.124 , pp. 23-30
    • Ahsan, H.1    Hadi, S.M.2
  • 10
    • 0028948839 scopus 로고
    • A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability
    • G.L. Amidon, H. Lennernäs, V.P. Shah and J.R. Crison (1995) A theoretical basis for a biopharmaceutic drug classification: the correlation of in vitro drug product dissolution and in vivo bioavailability. Pharm. Res. 12 413-420.
    • (1995) Pharm. Res. , vol.12 , pp. 413-420
    • Amidon, G.L.1    Lennernäs, H.2    Shah, V.P.3    Crison, J.R.4
  • 11
    • 84858709095 scopus 로고    scopus 로고
    • Administration of resveratrol: what formulation solutions to bioavailability limitations?
    • A. Amri, J.C.S. Sfar and C. Charrueau (2012) Administration of resveratrol: what formulation solutions to bioavailability limitations? J. Control. Rel. 158 182-193.
    • (2012) J. Control. Rel. , vol.158 , pp. 182-193
    • Amri, A.1    Sfar, J.C.S.2    Charrueau, C.3
  • 13
    • 79951923564 scopus 로고    scopus 로고
    • The bioflavonoid kaempferol is an Abcg2 substrate and inhibits Abcg2-mediated quercetin efflux
    • G. An, J. Gallegos and M.E. Morris (2011) The bioflavonoid kaempferol is an Abcg2 substrate and inhibits Abcg2-mediated quercetin efflux. Drug Metab. Dispos. 39 426-432.
    • (2011) Drug Metab. Dispos. , vol.39 , pp. 426-432
    • An, G.1    Gallegos, J.2    Morris, M.E.3
  • 14
    • 0036176413 scopus 로고    scopus 로고
    • Nutraceuticals: a piece of history, present status, and outlook
    • W. Andlauer and P. Fürst (2002) Nutraceuticals: a piece of history, present status, and outlook. Food Res. Int. 35 171-176.
    • (2002) Food Res. Int. , vol.35 , pp. 171-176
    • Andlauer, W.1    Fürst, P.2
  • 15
    • 67649970502 scopus 로고    scopus 로고
    • The universality of low-energy nanoemulsification
    • N. Anton and T.F. Vandamme (2009) The universality of low-energy nanoemulsification. Int. J. Pharm. 377(1–2), 142-147.
    • (2009) Int. J. Pharm. , vol.377 , Issue.1-2 , pp. 142-147
    • Anton, N.1    Vandamme, T.F.2
  • 16
    • 44749087481 scopus 로고    scopus 로고
    • Design and production of nanoparticles formulated from nanoemulsion templates: a review
    • N. Anton, J.P. Benoit and P. Saulnier (2008) Design and production of nanoparticles formulated from nanoemulsion templates: a review. J. Control Rel. 128 185-199.
    • (2008) J. Control Rel. , vol.128 , pp. 185-199
    • Anton, N.1    Benoit, J.P.2    Saulnier, P.3
  • 17
    • 84855688731 scopus 로고    scopus 로고
    • Preparation of lipid nanoemulsions incorporating curcumin for cancer therapy
    • S. Anuchapreeda, Y. Fukumori, S. Okonogi and H. Ichikawa (2012) Preparation of lipid nanoemulsions incorporating curcumin for cancer therapy. J. Nanotechnol. 41 1-11.
    • (2012) J. Nanotechnol. , vol.41 , pp. 1-11
    • Anuchapreeda, S.1    Fukumori, Y.2    Okonogi, S.3    Ichikawa, H.4
  • 18
    • 84907882650 scopus 로고    scopus 로고
    • Factorial design applied to the optimization of lipid composition of topical antiherpetic nanoemulsions containing isoflavone genistein
    • D.F. Argenta, C.B. de Mattos, F.D. Misturini, L.S. Koester, V.L. Bassani, C.M. Simões and H.F. Teixeira (2014) Factorial design applied to the optimization of lipid composition of topical antiherpetic nanoemulsions containing isoflavone genistein. Int. J. Nanomed. 9 4737-4747.
    • (2014) Int. J. Nanomed. , vol.9 , pp. 4737-4747
    • Argenta, D.F.1    de Mattos, C.B.2    Misturini, F.D.3    Koester, L.S.4    Bassani, V.L.5    Simões, C.M.6    Teixeira, H.F.7
  • 21
    • 84928493556 scopus 로고    scopus 로고
    • Challenges and solutions to incorporation of nutraceuticals in foods
    • M.A. Augustin and L. Sanguansri (2015) Challenges and solutions to incorporation of nutraceuticals in foods. Annu. Rev. Food Sci. Technol. 5 463-477.
    • (2015) Annu. Rev. Food Sci. Technol. , vol.5 , pp. 463-477
    • Augustin, M.A.1    Sanguansri, L.2
  • 22
    • 84930518027 scopus 로고    scopus 로고
    • Self-nanoemulsifying drug delivery system of stabilized ellagic acid–phospholipid complex with improved dissolution and permeability
    • A.M. Avachat and V.G. Patel (2015) Self-nanoemulsifying drug delivery system of stabilized ellagic acid–phospholipid complex with improved dissolution and permeability. Saudi Pharm. J. 23 276-289.
    • (2015) Saudi Pharm. J. , vol.23 , pp. 276-289
    • Avachat, A.M.1    Patel, V.G.2
  • 23
    • 0035468033 scopus 로고    scopus 로고
    • Physicochemical profiling (solubility, permeability, and charge state)
    • A. Avdeef (2001) Physicochemical profiling (solubility, permeability, and charge state). Curr. Top. Med. Chem. 1 277-351.
    • (2001) Curr. Top. Med. Chem. , vol.1 , pp. 277-351
    • Avdeef, A.1
  • 24
    • 27844474247 scopus 로고    scopus 로고
    • Drug discovery from medicinal plants
    • M.J. Balunas and A.D. Kinghorn (2005) Drug discovery from medicinal plants. Life Sci. 78 431-441.
    • (2005) Life Sci. , vol.78 , pp. 431-441
    • Balunas, M.J.1    Kinghorn, A.D.2
  • 25
    • 0242267999 scopus 로고    scopus 로고
    • Phospholipids affect the intestinal absorption of carotenoids in mice
    • V. Baskaran, T. Sugawara and A. Nagao (2003) Phospholipids affect the intestinal absorption of carotenoids in mice. Lipids. 38 705-711.
    • (2003) Lipids. , vol.38 , pp. 705-711
    • Baskaran, V.1    Sugawara, T.2    Nagao, A.3
  • 26
    • 33745962138 scopus 로고    scopus 로고
    • Therapeutic potential of resveratrol: the in vivo evidence
    • A.J. Baur and D.A. Sinclair (2006) Therapeutic potential of resveratrol: the in vivo evidence. Nat. Rev. 500 493-506.
    • (2006) Nat. Rev. , vol.500 , pp. 493-506
    • Baur, A.J.1    Sinclair, D.A.2
  • 27
    • 0034807847 scopus 로고    scopus 로고
    • Transport of lipophilic drug molecules in a new mucus-secreting cell culture model based on HT29-MTX cells
    • I. Behrens, P. Stenberg, P. Artursson and T. Kissel (2001) Transport of lipophilic drug molecules in a new mucus-secreting cell culture model based on HT29-MTX cells. Pharm. Res 18 1138-1145.
    • (2001) Pharm. Res , vol.18 , pp. 1138-1145
    • Behrens, I.1    Stenberg, P.2    Artursson, P.3    Kissel, T.4
  • 29
    • 84875337834 scopus 로고    scopus 로고
    • A transdermal delivery system to enhance quercetin nanoparticle permeability
    • D. Bennet and S. Kim (2013) A transdermal delivery system to enhance quercetin nanoparticle permeability. J Biomater. Sci. Polym. Ed. 24 185-209.
    • (2013) J Biomater. Sci. Polym. Ed. , vol.24 , pp. 185-209
    • Bennet, D.1    Kim, S.2
  • 32
    • 83455263445 scopus 로고    scopus 로고
    • Bioactive compounds in plants: benefits and risks for man and animals
    • (Eds)., Oslo. Nov., 13–14, 1–250
    • Bernhoft, A., 2008. (Eds). Bioactive compounds in plants: benefits and risks for man and animals. Proceedings from a symposium held at The Norwegian Academy of Science and Letters, Oslo. Nov. 13–14, 1–250. http://www.dnva.no/binfil/download.php?tid=48677.
    • (2008) Proceedings from a symposium held at The Norwegian Academy of Science and Letters
    • Bernhoft, A.1
  • 34
    • 84886078963 scopus 로고    scopus 로고
    • Neuroprotective effect of lutein against 3-nitropropionic acid-induced’Huntington’s disease-like symptoms: possible behavioral, biochemical, and cellular alterations
    • Y. Binawade and A. Jagtap (2013) Neuroprotective effect of lutein against 3-nitropropionic acid-induced’Huntington’s disease-like symptoms: possible behavioral, biochemical, and cellular alterations. J. Med. Food 16 934-943.
    • (2013) J. Med. Food , vol.16 , pp. 934-943
    • Binawade, Y.1    Jagtap, A.2
  • 35
    • 84890497517 scopus 로고    scopus 로고
    • Mixed lipid phase SMEDDS as an innovative approach to enhance resveratrol solubility
    • K. Bolko, A. Zvonar and M. Gašperlin (2014) Mixed lipid phase SMEDDS as an innovative approach to enhance resveratrol solubility. Drug Dev. Ind. Pharm 40 102-109.
    • (2014) Drug Dev. Ind. Pharm , vol.40 , pp. 102-109
    • Bolko, K.1    Zvonar, A.2    Gašperlin, M.3
  • 36
    • 84897691215 scopus 로고    scopus 로고
    • Nanodelivery of bioactive components for food applications: types of delivery systems, properties, and their effect on ADME profiles and toxicity of nanoparticles
    • T. Borel and C.M. Sabliov (2014) Nanodelivery of bioactive components for food applications: types of delivery systems, properties, and their effect on ADME profiles and toxicity of nanoparticles. Annu. Rev. Food Sci. Technol. 5 197-213.
    • (2014) Annu. Rev. Food Sci. Technol. , vol.5 , pp. 197-213
    • Borel, T.1    Sabliov, C.M.2
  • 37
    • 3242721638 scopus 로고    scopus 로고
    • Nano-emulsion formulation using spontaneous emulsification: solvent, oil, and surfactant optimisation
    • K. Bouchemal, S. Briancon, E. Perrier and H. Fessi (2004) Nano-emulsion formulation using spontaneous emulsification: solvent, oil, and surfactant optimisation. Int. J. Pharm. 280 241-251.
    • (2004) Int. J. Pharm. , vol.280 , pp. 241-251
    • Bouchemal, K.1    Briancon, S.2    Perrier, E.3    Fessi, H.4
  • 39
    • 84895070725 scopus 로고    scopus 로고
    • Nutraceutical-based therapeutics and formulation strategies augmenting their efficiency to complement modern medicine: an overview
    • M.C. Braithwaite, C. Tyagi, L.K. Tomar, P. Kumar, Y.E. Choonara and V. Pillay (2014) Nutraceutical-based therapeutics and formulation strategies augmenting their efficiency to complement modern medicine: an overview. J. Funct. Food 6 82-99.
    • (2014) J. Funct. Food , vol.6 , pp. 82-99
    • Braithwaite, M.C.1    Tyagi, C.2    Tomar, L.K.3    Kumar, P.4    Choonara, Y.E.5    Pillay, V.6
  • 40
    • 0031928015 scopus 로고    scopus 로고
    • Nutraceuticals: poised for a healthy slice of the healthcare market?
    • V. Brower (1998) Nutraceuticals: poised for a healthy slice of the healthcare market? Nat. Biotechnol. 16 728-731.
    • (1998) Nat. Biotechnol. , vol.16 , pp. 728-731
    • Brower, V.1
  • 41
    • 61449243865 scopus 로고    scopus 로고
    • Associations between lutein, zeaxanthin, and age-related macular degeneration: an overview
    • S. Carpentier, M. Knaus and M. Suh (2009) Associations between lutein, zeaxanthin, and age-related macular degeneration: an overview. Crit. Rev. Food Sci. Nutr. 49 313-326.
    • (2009) Crit. Rev. Food Sci. Nutr. , vol.49 , pp. 313-326
    • Carpentier, S.1    Knaus, M.2    Suh, M.3
  • 44
    • 68349160715 scopus 로고    scopus 로고
    • Lipid – an emerging platform for oral delivery of drugs with poor bioavailability
    • S. Chakraborty, D. Shukla, B. Mishra and S. Singh (2009) Lipid – an emerging platform for oral delivery of drugs with poor bioavailability. Eur. J. Pharm. Biopharm. 73 1-15.
    • (2009) Eur. J. Pharm. Biopharm. , vol.73 , pp. 1-15
    • Chakraborty, S.1    Shukla, D.2    Mishra, B.3    Singh, S.4
  • 45
    • 84928801703 scopus 로고    scopus 로고
    • Insights into drug discovery from natural products through structural modification
    • J. Chen, W. Li, H. Yao and J. Xu (2015) Insights into drug discovery from natural products through structural modification. Fitoterapia. 103 231-241.
    • (2015) Fitoterapia. , vol.103 , pp. 231-241
    • Chen, J.1    Li, W.2    Yao, H.3    Xu, J.4
  • 47
    • 85088854617 scopus 로고    scopus 로고
    • Mini-review on edible mushrooms as source of dietary fiber: preparation and health benefits
    • P.C.K. Cheung (2013) Mini-review on edible mushrooms as source of dietary fiber: preparation and health benefits. Food Sci. Human Wellness 2 162-166.
    • (2013) Food Sci. Human Wellness , vol.2 , pp. 162-166
    • Cheung, P.C.K.1
  • 48
    • 84896706625 scopus 로고    scopus 로고
    • Droplet size and composition of nutraceutical nanoemulsions influences bioavailability of long chain fatty acids and coenzyme Q10
    • H.T. Cho, L. Salvia-Trujillo, J. Kim, Y. Park, H. Xiao and D.J. McClements (2014) Droplet size and composition of nutraceutical nanoemulsions influences bioavailability of long chain fatty acids and coenzyme Q10. Food Chem. 156 117-122.
    • (2014) Food Chem. , vol.156 , pp. 117-122
    • Cho, H.T.1    Salvia-Trujillo, L.2    Kim, J.3    Park, Y.4    Xiao, H.5    McClements, D.J.6
  • 49
    • 79958294765 scopus 로고    scopus 로고
    • Characterization of capsaicin-loaded nanoemulsions stabilized with alginate and chitosan by self-assembly
    • A.J. Choi, C.J. Kim, Y.J. Cho, J.K. Hwang and C.T. Kim (2011) Characterization of capsaicin-loaded nanoemulsions stabilized with alginate and chitosan by self-assembly. Food Bioproc. Technol. 4 1119-1126.
    • (2011) Food Bioproc. Technol. , vol.4 , pp. 1119-1126
    • Choi, A.J.1    Kim, C.J.2    Cho, Y.J.3    Hwang, J.K.4    Kim, C.T.5
  • 50
    • 84876002671 scopus 로고    scopus 로고
    • Natural products: a continuing source of novel drug leads
    • C.M. Cragg and D.J. Newman (2013) Natural products: a continuing source of novel drug leads. Biochim. Biophys. Acta 1830 3670-3695.
    • (2013) Biochim. Biophys. Acta , vol.1830 , pp. 3670-3695
    • Cragg, C.M.1    Newman, D.J.2
  • 51
    • 62749095208 scopus 로고    scopus 로고
    • Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems
    • J. Cui, B. Yu, Y. Zhao, W. Zhu, H. Li, H. Lou and G. Zhai (2009) Enhancement of oral absorption of curcumin by self-microemulsifying drug delivery systems. Int. J. Pharm. 371 148-155.
    • (2009) Int. J. Pharm. , vol.371 , pp. 148-155
    • Cui, J.1    Yu, B.2    Zhao, Y.3    Zhu, W.4    Li, H.5    Lou, H.6    Zhai, G.7
  • 52
    • 72949123710 scopus 로고    scopus 로고
    • Prediction of solubility and permeability class membership: provisional BCS classification o’ the world’s top oral drugs
    • A. Dahan, J.M. Miller and G.L. Amidon (2009) Prediction of solubility and permeability class membership: provisional BCS classification o’ the world’s top oral drugs. AAPS J. 11 740-746.
    • (2009) AAPS J. , vol.11 , pp. 740-746
    • Dahan, A.1    Miller, J.M.2    Amidon, G.L.3
  • 53
    • 34250756115 scopus 로고    scopus 로고
    • Resveratrol: a therapeutic promise for cardiovascular diseases
    • S. Das and D.K. Das (2007) Resveratrol: a therapeutic promise for cardiovascular diseases. Recent Pat. Cardiovasc. Drug Discov. 2 133-138.
    • (2007) Recent Pat. Cardiovasc. Drug Discov. , vol.2 , pp. 133-138
    • Das, S.1    Das, D.K.2
  • 56
    • 84904651099 scopus 로고    scopus 로고
    • Nutraceutical delivery systems: resveratrol encapsulation in grape seed oil nanoemulsions formed by spontaneous emulsification
    • G. Davidov-Pardo and D.J. McClements (2015) Nutraceutical delivery systems: resveratrol encapsulation in grape seed oil nanoemulsions formed by spontaneous emulsification. Food Chem. 167 205-212.
    • (2015) Food Chem. , vol.167 , pp. 205-212
    • Davidov-Pardo, G.1    McClements, D.J.2
  • 58
    • 79960995369 scopus 로고    scopus 로고
    • Antiangiogenic effects of betulinic acid administered in nanoemulsion formulation using chorioallantoic membrane assay
    • C.A. Dehelean, S. Feflea, S. Ganta and M. Amiji (2011) Antiangiogenic effects of betulinic acid administered in nanoemulsion formulation using chorioallantoic membrane assay. J Biomed. Nanotechnol. 7 317-324.
    • (2011) J Biomed. Nanotechnol. , vol.7 , pp. 317-324
    • Dehelean, C.A.1    Feflea, S.2    Ganta, S.3    Amiji, M.4
  • 59
    • 33745673024 scopus 로고    scopus 로고
    • Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA Study
    • C. Delcourt, I. Carrière, M. Delage, P. Barberger-Gateau and W. Schalch POLA Study Group (2006) Plasma lutein and zeaxanthin and other carotenoids as modifiable risk factors for age-related maculopathy and cataract: the POLA Study. Invest. Ophth. Vis. Sci. 47 2329-2335.
    • (2006) Invest. Ophth. Vis. Sci. , vol.47 , pp. 2329-2335
    • Delcourt, C.1    Carrière, I.2    Delage, M.3    Barberger-Gateau, P.4    Schalch, W.5
  • 60
    • 63249110007 scopus 로고    scopus 로고
    • Potential use of tight junction modulators to reversibly open membranous barriers and improve drug delivery
    • M.A. Deli (2009) Potential use of tight junction modulators to reversibly open membranous barriers and improve drug delivery. Biochim. Biophys. Acta. 788 892-910.
    • (2009) Biochim. Biophys. Acta. , vol.788 , pp. 892-910
    • Deli, M.A.1
  • 61
    • 84883420601 scopus 로고    scopus 로고
    • Metabolism and permeability of curcumin in cultured Caco-2 cells
    • J.S. Dempe, R.K. Scheerle, E. Pfeiffer and M. Metzler (2013) Metabolism and permeability of curcumin in cultured Caco-2 cells. Mol. Nutr. Food Res. 57 1543-1549.
    • (2013) Mol. Nutr. Food Res. , vol.57 , pp. 1543-1549
    • Dempe, J.S.1    Scheerle, R.K.2    Pfeiffer, E.3    Metzler, M.4
  • 62
    • 84868033910 scopus 로고    scopus 로고
    • Overcoming poor oral bioavailability using nanoparticle formulations: opportunities and limitations
    • P.P. Desai, A.A. Date and V.B. Patravale (2012) Overcoming poor oral bioavailability using nanoparticle formulations: opportunities and limitations. Drug Discov. Today Technol. 9 e87-e95.
    • (2012) Drug Discov. Today Technol. , vol.9 , pp. e87-e95
    • Desai, P.P.1    Date, A.A.2    Patravale, V.B.3
  • 63
    • 0034666458 scopus 로고    scopus 로고
    • Phytochemicals: nutraceuticals and human health
    • C.J. Dillard and J.B. German (2000) Phytochemicals: nutraceuticals and human health. J. Sci. Food Agric. 80 1744-1756.
    • (2000) J. Sci. Food Agric. , vol.80 , pp. 1744-1756
    • Dillard, C.J.1    German, J.B.2
  • 64
    • 40049110714 scopus 로고    scopus 로고
    • Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule?
    • P.D. Dobson and D.B. Kell (2008) Carrier-mediated cellular uptake of pharmaceutical drugs: an exception or the rule? Nat. Rev. Drug Discov. 7 205-220.
    • (2008) Nat. Rev. Drug Discov. , vol.7 , pp. 205-220
    • Dobson, P.D.1    Kell, D.B.2
  • 65
    • 84941265553 scopus 로고    scopus 로고
    • Self-microemulsifying drug delivery system (SMEDDS): challenges and road ahead
    • S. Dokania and A. Joshi (2014) Self-microemulsifying drug delivery system (SMEDDS): challenges and road ahead. Drug Deliv. Early Online 10.3109/10717544.2014.896058
    • (2014) Drug Deliv. Early Online
    • Dokania, S.1    Joshi, A.2
  • 66
    • 78049291493 scopus 로고    scopus 로고
    • Development of novel pea protein-based nanoemulsions for delivery of nutraceuticals
    • F. Donsì, B. Senatore, Q. Huang and G. Ferrari (2010) Development of novel pea protein-based nanoemulsions for delivery of nutraceuticals. J. Agric. Food Chem. 58 10653-10660.
    • (2010) J. Agric. Food Chem. , vol.58 , pp. 10653-10660
    • Donsì, F.1    Senatore, B.2    Huang, Q.3    Ferrari, G.4
  • 68
    • 85168634536 scopus 로고    scopus 로고
    • Topical quercetin nanoemulsions: optimization of preparation using chemometric approaches
    • P. Ebrahimi and S. Salmanpour (2014) Topical quercetin nanoemulsions: optimization of preparation using chemometric approaches. Pharm. Chem. J. 48 402-407.
    • (2014) Pharm. Chem. J. , vol.48 , pp. 402-407
    • Ebrahimi, P.1    Salmanpour, S.2
  • 69
    • 84869481195 scopus 로고    scopus 로고
    • Scientific Opinion on the re-evaluation of curcumin (E 100) as a food additive, EFSA Panel on Food Additives and Nutrient Sources added to Food
    • EFSA, European Food Safety Authority. 2010. Scientific Opinion on the re-evaluation of curcumin (E 100) as a food additive, EFSA Panel on Food Additives and Nutrient Sources added to Food. EFSA J. 8, 1679. http://www.efsa.europa.eu/fr/scdocs/doc/1679.pdf.
    • (2010) EFSA J. , vol.8 , pp. 1679
  • 71
    • 84878580426 scopus 로고    scopus 로고
    • Effects of formulation on the bioavailability of lutein and zeaxanthin: a randomized, double-blind, cross-over, comparative, single-dose study in healthy subjects
    • M. Evans, M. Beck, J. Elliott, S. Etheve, R. Roberts and W. Schalch (2013) Effects of formulation on the bioavailability of lutein and zeaxanthin: a randomized, double-blind, cross-over, comparative, single-dose study in healthy subjects. Eur. J. Nutr. 52 1381-1391.
    • (2013) Eur. J. Nutr. , vol.52 , pp. 1381-1391
    • Evans, M.1    Beck, M.2    Elliott, J.3    Etheve, S.4    Roberts, R.5    Schalch, W.6
  • 72
    • 75749088052 scopus 로고    scopus 로고
    • Development of topical nanoemulsions containing quercetin and 3-O-methylquercetin
    • D. Fasolo, V.L. Bassani and H.F. Teixeira (2009) Development of topical nanoemulsions containing quercetin and 3-O-methylquercetin. Pharmazie. 64 726-730.
    • (2009) Pharmazie. , vol.64 , pp. 726-730
    • Fasolo, D.1    Bassani, V.L.2    Teixeira, H.F.3
  • 73
    • 18844402089 scopus 로고    scopus 로고
    • Functional foods, herbs, and nutraceuticals: toward biochemical mechanisms of healthy aging
    • C.K.B. Ferrari (2004) Functional foods, herbs, and nutraceuticals: toward biochemical mechanisms of healthy aging. Biogerontology. 5 275-289.
    • (2004) Biogerontology. , vol.5 , pp. 275-289
    • Ferrari, C.K.B.1
  • 74
    • 0346059361 scopus 로고    scopus 로고
    • The French Paradox: lessons for other countries
    • J. Ferrières (2004) The French Paradox: lessons for other countries. Heart 90 107-111.
    • (2004) Heart , vol.90 , pp. 107-111
    • Ferrières, J.1
  • 77
    • 77956457439 scopus 로고    scopus 로고
    • Resveratrol and derivatives for the prevention and treatment of cancer
    • S. Fulda (2010) Resveratrol and derivatives for the prevention and treatment of cancer. Drug Discov. Today. 15 757-765.
    • (2010) Drug Discov. Today. , vol.15 , pp. 757-765
    • Fulda, S.1
  • 78
    • 0033391399 scopus 로고    scopus 로고
    • Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells
    • A. Galijatovic, Y. Otake, U.K. Walle and T. Walle (1999) Extensive metabolism of the flavonoid chrysin by human Caco-2 and Hep G2 cells. Xenobiotica. 29 1241-1256.
    • (1999) Xenobiotica. , vol.29 , pp. 1241-1256
    • Galijatovic, A.1    Otake, Y.2    Walle, U.K.3    Walle, T.4
  • 79
    • 67249106291 scopus 로고    scopus 로고
    • Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells
    • S. Ganta and M. Amiji (2009) Coadministration of paclitaxel and curcumin in nanoemulsion formulations to overcome multidrug resistance in tumor cells. Mol. Pharm. 6 928-939.
    • (2009) Mol. Pharm. , vol.6 , pp. 928-939
    • Ganta, S.1    Amiji, M.2
  • 80
    • 78049328392 scopus 로고    scopus 로고
    • Curcumin enhances oral bioavailability and antitumor therapeutic efficacy of paclitaxel upon administration in nanoemulsion formulation
    • S. Ganta, H. Devalapally and M. Amiji (2010) Curcumin enhances oral bioavailability and antitumor therapeutic efficacy of paclitaxel upon administration in nanoemulsion formulation. J. Pharm. Sci. 99 4630-4641.
    • (2010) J. Pharm. Sci. , vol.99 , pp. 4630-4641
    • Ganta, S.1    Devalapally, H.2    Amiji, M.3
  • 81
    • 70449500984 scopus 로고    scopus 로고
    • Micro- and nanoemulsions for delivery of functional food ingredients
    • N. Garti (Ed.), Cambridge, UK: Woodhead Publishing
    • N. Garti and I. Yuli-Amar (2008) Micro- and nanoemulsions for delivery of functional food ingredients. N. Garti (Ed.) Delivery and Controlled Release of Bioactives in Foods and Nutraceuticals Cambridge, UK: Woodhead Publishing 149-179.
    • (2008) Delivery and Controlled Release of Bioactives in Foods and Nutraceuticals , pp. 149-179
    • Garti, N.1    Yuli-Amar, I.2
  • 82
    • 84921996211 scopus 로고    scopus 로고
    • Formulation of gammaoryzanol-loaded nanoparticles for potential application in fortifying food products
    • S. Ghaderi, S. Ghanbarzadeh, Z. Mohammadhassani and H. Hamishehkar (2014) Formulation of gammaoryzanol-loaded nanoparticles for potential application in fortifying food products. Adv. Pharm. Bull. 4 549-554.
    • (2014) Adv. Pharm. Bull. , vol.4 , pp. 549-554
    • Ghaderi, S.1    Ghanbarzadeh, S.2    Mohammadhassani, Z.3    Hamishehkar, H.4
  • 83
    • 84890990884 scopus 로고    scopus 로고
    • Eugenol-loaded antimicrobial nanoemulsion preserves fruit juice against, microbial spoilage
    • V. Ghosh, A. Mukherjee and N. Chandrasekaran (2014) Eugenol-loaded antimicrobial nanoemulsion preserves fruit juice against, microbial spoilage. Colloid. Surf. B. 114 392-397.
    • (2014) Colloid. Surf. B. , vol.114 , pp. 392-397
    • Ghosh, V.1    Mukherjee, A.2    Chandrasekaran, N.3
  • 84
    • 32544442655 scopus 로고    scopus 로고
    • Critical role of tight junctions in drug delivery across epithelial and endothelial cell layers
    • L. González-Mariscal, P. Nava and S. Hernández (2005) Critical role of tight junctions in drug delivery across epithelial and endothelial cell layers. J. Membr. Biol. 207 55-68.
    • (2005) J. Membr. Biol. , vol.207 , pp. 55-68
    • González-Mariscal, L.1    Nava, P.2    Hernández, S.3
  • 85
    • 84863875607 scopus 로고    scopus 로고
    • Glycolipids improve lutein bioavailability and accumulation in eyes in mice
    • A. Gorusupudi and B. Vallikannan (2012) Glycolipids improve lutein bioavailability and accumulation in eyes in mice. Eur. J. Lipid Sci. Technol. 114 710-717.
    • (2012) Eur. J. Lipid Sci. Technol. , vol.114 , pp. 710-717
    • Gorusupudi, A.1    Vallikannan, B.2
  • 86
    • 0345862319 scopus 로고    scopus 로고
    • Nutraceuticals, apoptosis, and disease prevention
    • A. Gosslau and K.Y. Chen (2004) Nutraceuticals, apoptosis, and disease prevention. Nutrition. 20 95-102.
    • (2004) Nutrition. , vol.20 , pp. 95-102
    • Gosslau, A.1    Chen, K.Y.2
  • 88
    • 84904471447 scopus 로고    scopus 로고
    • Codelivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin
    • A.E. Grill, B. Koniar and J. Panyam (2014) Codelivery of natural metabolic inhibitors in a self-microemulsifying drug delivery system for improved oral bioavailability of curcumin. Drug Deliv. Transl. Res. 4 344-352.
    • (2014) Drug Deliv. Transl. Res. , vol.4 , pp. 344-352
    • Grill, A.E.1    Koniar, B.2    Panyam, J.3
  • 90
    • 84863115185 scopus 로고    scopus 로고
    • Discovery of curcumin, a component of golden spice, and its miraculous biological activities
    • S.C. Gupta, S. Patchva, W. Koh and B.B. Aggarwal (2012) Discovery of curcumin, a component of golden spice, and its miraculous biological activities. Clin. Exp. Pharmacol. Physiol. 39 283-299.
    • (2012) Clin. Exp. Pharmacol. Physiol. , vol.39 , pp. 283-299
    • Gupta, S.C.1    Patchva, S.2    Koh, W.3    Aggarwal, B.B.4
  • 91
    • 79956312428 scopus 로고    scopus 로고
    • Emerging technologies for improving phytochemical bioavailability: benefits and risks
    • B.J. Gurley (2011) Emerging technologies for improving phytochemical bioavailability: benefits and risks. Clin. Pharmacol. Therapeutics 89(6), 915-919.
    • (2011) Clin. Pharmacol. Therapeutics , vol.89 , Issue.6 , pp. 915-919
    • Gurley, B.J.1
  • 92
    • 0034909129 scopus 로고    scopus 로고
    • A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol
    • J. Gusman, H. Maonne and G. Atassi (2001) A reappraisal of the potential chemopreventive and chemotherapeutic properties of resveratrol. Carcinogenesis 22 1111-1117.
    • (2001) Carcinogenesis , vol.22 , pp. 1111-1117
    • Gusman, J.1    Maonne, H.2    Atassi, G.3
  • 93
    • 0034235855 scopus 로고    scopus 로고
    • Nutraceuticals and functional foods: introduction and meaning
    • G. Hardy (2000) Nutraceuticals and functional foods: introduction and meaning. Nutrition 16 688-697.
    • (2000) Nutrition , vol.16 , pp. 688-697
    • Hardy, G.1
  • 94
    • 77955052628 scopus 로고    scopus 로고
    • Physicochemical and pharmacological characterization of α-tocopherol-loaded nanoemulsion system
    • J. Hatanaka, H. Chikamori, H. Sato, S. Uchida, K. Debari, S. Onoue and S. Yamada (2010) Physicochemical and pharmacological characterization of α-tocopherol-loaded nanoemulsion system. Int. J. Pharm. 396 188-193.
    • (2010) Int. J. Pharm. , vol.396 , pp. 188-193
    • Hatanaka, J.1    Chikamori, H.2    Sato, H.3    Uchida, S.4    Debari, K.5    Onoue, S.6    Yamada, S.7
  • 95
    • 84891613383 scopus 로고    scopus 로고
    • The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancers
    • M. Heger, R.F. van Golen, M. Broekgaarden and M.C. Michel (2014) The molecular basis for the pharmacokinetics and pharmacodynamics of curcumin and its metabolites in relation to cancers. Pharmacol. Rev. 66 222-307.
    • (2014) Pharmacol. Rev. , vol.66 , pp. 222-307
    • Heger, M.1    van Golen, R.F.2    Broekgaarden, M.3    Michel, M.C.4
  • 96
    • 0026843925 scopus 로고
    • Chemical and physiological behavior of feed carotenoids and their effects on pigmentation
    • H. Hencken (1992) Chemical and physiological behavior of feed carotenoids and their effects on pigmentation. Poultry Sci. 71 711-717.
    • (1992) Poultry Sci. , vol.71 , pp. 711-717
    • Hencken, H.1
  • 98
    • 0028321502 scopus 로고
    • Mechanisms of absorption enhancement and tight junction regulation
    • J. Hochman and P. Artursson (1994) Mechanisms of absorption enhancement and tight junction regulation. J. Control. Rel. 29 253-267.
    • (1994) J. Control. Rel. , vol.29 , pp. 253-267
    • Hochman, J.1    Artursson, P.2
  • 99
    • 84928348898 scopus 로고    scopus 로고
    • Nanocomplexes arising from protein-polysaccharide electrostatic interaction as a promising carrier for nutraceutical compounds
    • S.M.H. Hosseini, Z. Emam-Djomeh, P. Sabatino and P. Van der Meeren (2015) Nanocomplexes arising from protein-polysaccharide electrostatic interaction as a promising carrier for nutraceutical compounds. Food Hydrocolloid. 50 16-26.
    • (2015) Food Hydrocolloid. , vol.50 , pp. 16-26
    • Hosseini, S.M.H.1    Emam-Djomeh, Z.2    Sabatino, P.3    Van der Meeren, P.4
  • 100
    • 0029311765 scopus 로고
    • The role of plants in traditional medicine and current therapy
    • P.J. Houghton (1995) The role of plants in traditional medicine and current therapy. J. Altern. Complement. Med. 1 131-143.
    • (1995) J. Altern. Complement. Med. , vol.1 , pp. 131-143
    • Houghton, P.J.1
  • 101
    • 84884944810 scopus 로고    scopus 로고
    • Nutrition and nutraceutical supplements for the treatment of hypertension: part I
    • M. Houston (2013) Nutrition and nutraceutical supplements for the treatment of hypertension: part I. J. Clin. Hypertens. (Greenwich) 15 752-757.
    • (2013) J. Clin. Hypertens. (Greenwich) , vol.15 , pp. 752-757
    • Houston, M.1
  • 102
    • 0026029402 scopus 로고
    • Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis
    • M.T. Huang, T. Lysz and T. Ferraro (1991) Inhibitory effects of curcumin on in vitro lipoxygenase and cyclooxygenase activities in mouse epidermis. Cancer Res. 51 813-819.
    • (1991) Cancer Res. , vol.51 , pp. 813-819
    • Huang, M.T.1    Lysz, T.2    Ferraro, T.3
  • 103
    • 74249109604 scopus 로고    scopus 로고
    • Bioavailability and delivery of nutraceuticals using nanotechnology
    • Q. Huang, H. Yu and Q. Ru (2010) Bioavailability and delivery of nutraceuticals using nanotechnology. J. Food Sci. 75 R50-R57.
    • (2010) J. Food Sci. , vol.75 , pp. R50-R57
    • Huang, Q.1    Yu, H.2    Ru, Q.3
  • 104
    • 84923221616 scopus 로고    scopus 로고
    • Changes following supplementation with lutein and zeaxanthin in retinal function in eyes with early age-related macular degeneration: a randomized, double-blind, placebo-controlled trial
    • Y.M. Huang, H.L. Dou, F.F. Huang, X.R. Xu, Z.Y. Zou, X.R. Lu and X.M. Lin (2015) Changes following supplementation with lutein and zeaxanthin in retinal function in eyes with early age-related macular degeneration: a randomized, double-blind, placebo-controlled trial. Br. J. Ophth. 99 371-375.
    • (2015) Br. J. Ophth. , vol.99 , pp. 371-375
    • Huang, Y.M.1    Dou, H.L.2    Huang, F.F.3    Xu, X.R.4    Zou, Z.Y.5    Lu, X.R.6    Lin, X.M.7
  • 105
    • 1342306855 scopus 로고    scopus 로고
    • Resveratrol protects myocardial ischemia–reperfusion injury through both NO-dependent and NO-independent mechanisms
    • L.M. Hung, M.J. Su and J.K. Chen (2004) Resveratrol protects myocardial ischemia–reperfusion injury through both NO-dependent and NO-independent mechanisms. Free Radic. Biol. Med. 36 774-781.
    • (2004) Free Radic. Biol. Med. , vol.36 , pp. 774-781
    • Hung, L.M.1    Su, M.J.2    Chen, J.K.3
  • 106
    • 33750063974 scopus 로고    scopus 로고
    • Development and evaluation of emulsion-liposome blends for resveratrol delivery
    • C.F. Hung, J.K. Chen, M.H. Liao, H.M. Lo and J.Y. Fang (2006) Development and evaluation of emulsion-liposome blends for resveratrol delivery. J. Nanosci. Nanotechnol. 6 2950-2958.
    • (2006) J. Nanosci. Nanotechnol. , vol.6 , pp. 2950-2958
    • Hung, C.F.1    Chen, J.K.2    Liao, M.H.3    Lo, H.M.4    Fang, J.Y.5
  • 108
    • 33746198333 scopus 로고    scopus 로고
    • Nanoemulsion production by sonication and microfluidization: a comparison
    • S.M. Jafari, Y. He and B. Bhandari (2006) Nanoemulsion production by sonication and microfluidization: a comparison. Int. J. Food Prop. 9 475-485.
    • (2006) Int. J. Food Prop. , vol.9 , pp. 475-485
    • Jafari, S.M.1    He, Y.2    Bhandari, B.3
  • 109
    • 34250637454 scopus 로고    scopus 로고
    • Optimization of nanoemulsions production by microfluidization
    • S.M. Jafari, Y. He and B. Bhandari (2007) Optimization of nanoemulsions production by microfluidization. Eur. Food Res. Technol. 225 733-741.
    • (2007) Eur. Food Res. Technol. , vol.225 , pp. 733-741
    • Jafari, S.M.1    He, Y.2    Bhandari, B.3
  • 110
    • 34248160590 scopus 로고    scopus 로고
    • Production of submicron emulsions by ultrasound and microfluidization techniques
    • S.M. Jafari, Y. He and B. Bhandari (2007) Production of submicron emulsions by ultrasound and microfluidization techniques. J. Food Eng. 82 487-488.
    • (2007) J. Food Eng. , vol.82 , pp. 487-488
    • Jafari, S.M.1    He, Y.2    Bhandari, B.3
  • 111
    • 84894501614 scopus 로고    scopus 로고
    • Characterization of β-carotene nanoemulsions prepared by microfluidization technique
    • Y.J. Jo and Y.J. Kwon (2014) Characterization of β-carotene nanoemulsions prepared by microfluidization technique. Food Sci. Biotechnol. 23 107-113.
    • (2014) Food Sci. Biotechnol. , vol.23 , pp. 107-113
    • Jo, Y.J.1    Kwon, Y.J.2
  • 112
    • 84867784644 scopus 로고    scopus 로고
    • A possible role for lutein and zeaxanthin in cognitive function in the elderly
    • E.J. Johnson (2012) A possible role for lutein and zeaxanthin in cognitive function in the elderly. Am. J. Clin. Nutr. 96 1161S-1165S.
    • (2012) Am. J. Clin. Nutr. , vol.96 , pp. 1161S-1165S
    • Johnson, E.J.1
  • 113
    • 84906514773 scopus 로고    scopus 로고
    • Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan
    • E.J. Johnson (2014) Role of lutein and zeaxanthin in visual and cognitive function throughout the lifespan. Nutr. Rev. 72 605-612.
    • (2014) Nutr. Rev. , vol.72 , pp. 605-612
    • Johnson, E.J.1
  • 114
    • 84880717987 scopus 로고    scopus 로고
    • SNEDDS curcumin formulation leads to enhanced protection from pain and functional deficits associated with diabetic neuropathy: an insight into its mechanism for neuroprotection
    • R.P. Joshi, G. Negi, A. Kumar, Y.B. Pawar, B. Munjal, A.K. Bansal and S.S. Sharma (2013) SNEDDS curcumin formulation leads to enhanced protection from pain and functional deficits associated with diabetic neuropathy: an insight into its mechanism for neuroprotection. Nanomedicine: NBM 9 776-785.
    • (2013) Nanomedicine: NBM , vol.9 , pp. 776-785
    • Joshi, R.P.1    Negi, G.2    Kumar, A.3    Pawar, Y.B.4    Munjal, B.5    Bansal, A.K.6    Sharma, S.S.7
  • 115
    • 0346039322 scopus 로고    scopus 로고
    • Nutraceutical: definition and introduction
    • E.K. Kalra (2003) Nutraceutical: definition and introduction. AAPS PharmSci. 5(Article 25), 1-2.
    • (2003) AAPS PharmSci. , vol.5 , Issue.Article 25 , pp. 1-2
    • Kalra, E.K.1
  • 116
    • 84874911815 scopus 로고    scopus 로고
    • Optimization of preparation conditions for quercetin nanoemulsions using response surface methodology
    • A. Karadag, X. Yang, B. Ozcelik and Q. Huang (2013) Optimization of preparation conditions for quercetin nanoemulsions using response surface methodology. J. Agric. Food Chem. 61 2130-2139.
    • (2013) J. Agric. Food Chem. , vol.61 , pp. 2130-2139
    • Karadag, A.1    Yang, X.2    Ozcelik, B.3    Huang, Q.4
  • 118
    • 84888836884 scopus 로고    scopus 로고
    • Resveratrol and related stilbenes: their antiaging and antiangiogenic properties
    • K.M. Kasiotis, H. Pratsinis, D. Kletsas and S.A. Haroutounian (2013) Resveratrol and related stilbenes: their antiaging and antiangiogenic properties. Food Chem. Toxicol. 61 112-120.
    • (2013) Food Chem. Toxicol. , vol.61 , pp. 112-120
    • Kasiotis, K.M.1    Pratsinis, H.2    Kletsas, D.3    Haroutounian, S.A.4
  • 119
    • 84930017644 scopus 로고    scopus 로고
    • Formulation design and in vitro evaluation of berberine loaded self-nanoemulsifying drug delivery system
    • Z. Ke, Z.-P. Zhu, Z.-Y. Xu, C. Fang and S.-Q. Hu (2015) Formulation design and in vitro evaluation of berberine loaded self-nanoemulsifying drug delivery system. Trop. J. Pharm. Res. 14 747-752.
    • (2015) Trop. J. Pharm. Res. , vol.14 , pp. 747-752
    • Ke, Z.1    Zhu, Z.-P.2    Xu, Z.-Y.3    Fang, C.4    Hu, S.-Q.5
  • 120
    • 85152842256 scopus 로고    scopus 로고
    • Kearney, 2014., All rights reserved. Reprinted with permission.
    • Kearney, A.T., 2014. Nutraceuticals: The Front Line of the Battle for Consumer Health, copyright A.T. Kearney, 2014. All rights reserved. Reprinted with permission. https://www.atkearney.com/documents/10192/4306155/Winning+the+Battle+for+Consumer+Healthcare+-+Nutraceuticals.pdf/e4c67b42-cb4b-436a-b50d-7b35c0508b95.
    • (2014) Nutraceuticals: The Front Line of the Battle for Consumer Health, copyright A.T.
    • Kearney, A.T.1
  • 122
    • 84933515226 scopus 로고    scopus 로고
    • Self-nanoemulsifying drug delivery system (SNEDDS) of the poorly water-soluble grapefruit flavonoid Naringenin: design, characterization, in vitro and in vivo evaluation
    • A.W. Khan, S. Kotta, S.H. Ansari, R.K. Sharma and J. Ali (2015) Self-nanoemulsifying drug delivery system (SNEDDS) of the poorly water-soluble grapefruit flavonoid Naringenin: design, characterization, in vitro and in vivo evaluation. Drug Deliv. 22 552-561.
    • (2015) Drug Deliv. , vol.22 , pp. 552-561
    • Khan, A.W.1    Kotta, S.2    Ansari, S.H.3    Sharma, R.K.4    Ali, J.5
  • 125
    • 0034991938 scopus 로고    scopus 로고
    • Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma–bearing mice
    • Y. Kimura and H. Okuda (2001) Resveratrol isolated from Polygonum cuspidatum root prevents tumor growth and metastasis to lung and tumor-induced neovascularization in Lewis lung carcinoma–bearing mice. J. Nutr. 131 1844-1849.
    • (2001) J. Nutr. , vol.131 , pp. 1844-1849
    • Kimura, Y.1    Okuda, H.2
  • 126
    • 0035138232 scopus 로고    scopus 로고
    • Pharmacognosy in the 21st century
    • A.D. Kinghorn (2001) Pharmacognosy in the 21st century. J. Pharm. Pharmacol. 53 135-148.
    • (2001) J. Pharm. Pharmacol. , vol.53 , pp. 135-148
    • Kinghorn, A.D.1
  • 127
    • 35449006733 scopus 로고    scopus 로고
    • Tight junction modulators: promising candidates for drug delivery
    • M. Kondoh and K. Yagi (2007) Tight junction modulators: promising candidates for drug delivery. Curr. Med. Chem. 14 2482-2488.
    • (2007) Curr. Med. Chem. , vol.14 , pp. 2482-2488
    • Kondoh, M.1    Yagi, K.2
  • 128
    • 0042866149 scopus 로고    scopus 로고
    • Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye
    • N.I. Krinsky, J.T. Landrum and R.A. Bone (2003) Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annu. Rev. Nutr. 23 171-203.
    • (2003) Annu. Rev. Nutr. , vol.23 , pp. 171-203
    • Krinsky, N.I.1    Landrum, J.T.2    Bone, R.A.3
  • 129
    • 58749114413 scopus 로고    scopus 로고
    • Now we are talking sense! Functional approaches to novel nutraceuticals and cosmeceuticals
    • M. Krohn, A. Kleber, G. Schaffar, U. Dechert and J. Eck (2008) Now we are talking sense! Functional approaches to novel nutraceuticals and cosmeceuticals. Biotechnol. J. 3 1147-1156.
    • (2008) Biotechnol. J. , vol.3 , pp. 1147-1156
    • Krohn, M.1    Kleber, A.2    Schaffar, G.3    Dechert, U.4    Eck, J.5
  • 130
    • 84871711798 scopus 로고    scopus 로고
    • Lipid-based formulations for oral delivery of lipophilic drugs
    • M. Kuentz (2012) Lipid-based formulations for oral delivery of lipophilic drugs. Drug Discov. Today Technol. 9 e97-e104.
    • (2012) Drug Discov. Today Technol. , vol.9 , pp. e97-e104
    • Kuentz, M.1
  • 131
    • 84871866642 scopus 로고    scopus 로고
    • Curcumin loaded nano globules for solubility enhancement: preparation, characterization, and ex vivo release study
    • A. Kumar, A. Ahuja, J. Ali and S. Baboota (2012) Curcumin loaded nano globules for solubility enhancement: preparation, characterization, and ex vivo release study. J. Nanosci. Nanotechnol. 12 8293-8302.
    • (2012) J. Nanosci. Nanotechnol. , vol.12 , pp. 8293-8302
    • Kumar, A.1    Ahuja, A.2    Ali, J.3    Baboota, S.4
  • 133
    • 0034775358 scopus 로고    scopus 로고
    • Lutein, zeaxanthin, and the macular pigment
    • J.T. Landrum and R.A. Bone (2001) Lutein, zeaxanthin, and the macular pigment. Arch. Biochem. Biophys 385 28-40.
    • (2001) Arch. Biochem. Biophys , vol.385 , pp. 28-40
    • Landrum, J.T.1    Bone, R.A.2
  • 134
    • 0013562371 scopus 로고    scopus 로고
    • The influence of intestinal mucus components on the diffusion of drugs
    • A.W. Larhed, P. Artursson and E. Björk (1998) The influence of intestinal mucus components on the diffusion of drugs. Pharm Res. 15 66-71.
    • (1998) Pharm Res. , vol.15 , pp. 66-71
    • Larhed, A.W.1    Artursson, P.2    Björk, E.3
  • 135
    • 67349144731 scopus 로고    scopus 로고
    • Minimising oil droplet size using ultrasonic emulsification
    • T. Leong, T. Wooster, S. Kentish and M. Ashokkumar (2009) Minimising oil droplet size using ultrasonic emulsification. Ultrason. Sonochem. 16(6), 721-727.
    • (2009) Ultrason. Sonochem. , vol.16 , Issue.6 , pp. 721-727
    • Leong, T.1    Wooster, T.2    Kentish, S.3    Ashokkumar, M.4
  • 136
    • 84873679516 scopus 로고    scopus 로고
    • Stability and bioaccessibility of β-carotene in nanoemulsions stabilized by modified starches
    • R. Liang, C.F. Shoemaker, X. Yang, F. Zhong and Q. Huang (2013) Stability and bioaccessibility of β-carotene in nanoemulsions stabilized by modified starches. J. Agric. Food Chem. 61 1249-1257.
    • (2013) J. Agric. Food Chem. , vol.61 , pp. 1249-1257
    • Liang, R.1    Shoemaker, C.F.2    Yang, X.3    Zhong, F.4    Huang, Q.5
  • 137
    • 34548240098 scopus 로고    scopus 로고
    • Natural polyphenol disposition via coupled metabolic pathways
    • Z. Liu and M. Hu (2007) Natural polyphenol disposition via coupled metabolic pathways. Expert. Opin. Drug Metab. Toxicol. 3 389-406.
    • (2007) Expert. Opin. Drug Metab. Toxicol. , vol.3 , pp. 389-406
    • Liu, Z.1    Hu, M.2
  • 138
    • 84920923138 scopus 로고    scopus 로고
    • Lutein and Zeaxanthin supplementation and association with visual function in age-related macular degeneration
    • R. Liu, T. Wang, B. Zhang, L. Qin, C. Wu, Q. Li and L. Ma (2014) Lutein and Zeaxanthin supplementation and association with visual function in age-related macular degeneration. Invest. Ophth. Vis. Sci. 56 252-258.
    • (2014) Invest. Ophth. Vis. Sci. , vol.56 , pp. 252-258
    • Liu, R.1    Wang, T.2    Zhang, B.3    Qin, L.4    Wu, C.5    Li, Q.6    Ma, L.7
  • 140
    • 67849091730 scopus 로고    scopus 로고
    • 2nd Edition, London, UK: Pharmaceutical Press, p. 1
    • B. Lockwood (2007) Nutraceuticals. 2nd Edition London, UK: Pharmaceutical Press p. 1
    • (2007) Nutraceuticals
    • Lockwood, B.1
  • 142
    • 84938848834 scopus 로고    scopus 로고
    • Transport of trans-tiliroside (kaempferol-3-β-D-(6″-p-coumaroyl-glucopyranoside) and related flavonoids across Caco-2 cells, as a model of absorption and metabolism in the small intestine
    • Accepted manuscript
    • Z. Luo, M.R. Morgan and A.J. Day (2015) Transport of trans-tiliroside (kaempferol-3-β-D-(6″-p-coumaroyl-glucopyranoside) and related flavonoids across Caco-2 cells, as a model of absorption and metabolism in the small intestine. Xenobiotica Accepted manuscript
    • (2015) Xenobiotica
    • Luo, Z.1    Morgan, M.R.2    Day, A.J.3
  • 143
    • 84899862640 scopus 로고    scopus 로고
    • Nanoemulsions for delivery of flavonoids: formulation and in vitro release of rutin as model drug
    • A.S. Macedo, S. Quelhas, A.M. Silva and E.B. Souto (2014) Nanoemulsions for delivery of flavonoids: formulation and in vitro release of rutin as model drug. Pharm. Dev. Technol. 19 677-680.
    • (2014) Pharm. Dev. Technol. , vol.19 , pp. 677-680
    • Macedo, A.S.1    Quelhas, S.2    Silva, A.M.3    Souto, E.B.4
  • 145
    • 33644901007 scopus 로고    scopus 로고
    • Multiple biological activities of curcumin: a short review
    • R.K. Maheshwari, A.K. Singh, J. Gaddipati and R.C. Srimal (2006) Multiple biological activities of curcumin: a short review. Life Sci. 78 2081-2087.
    • (2006) Life Sci. , vol.78 , pp. 2081-2087
    • Maheshwari, R.K.1    Singh, A.K.2    Gaddipati, J.3    Srimal, R.C.4
  • 146
    • 43249110151 scopus 로고    scopus 로고
    • Metabolism and disposition of resveratrol in the isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides
    • A. Maier-Salamon, B. Hagenauer, G. Reznicek, T. Szekeres, T. Thalhammer and W. Jäger (2008) Metabolism and disposition of resveratrol in the isolated perfused rat liver: role of Mrp2 in the biliary excretion of glucuronides. J. Pharm. Sci. 97 1615-1628.
    • (2008) J. Pharm. Sci. , vol.97 , pp. 1615-1628
    • Maier-Salamon, A.1    Hagenauer, B.2    Reznicek, G.3    Szekeres, T.4    Thalhammer, T.5    Jäger, W.6
  • 147
    • 84918562218 scopus 로고    scopus 로고
    • Apoptotic effects of eugenol-loaded nanoemulsions in human colon and liver cancer cell lines
    • H. Majeed, J. Antoniou and Z. Fang (2014) Apoptotic effects of eugenol-loaded nanoemulsions in human colon and liver cancer cell lines. Asian Pac. J. Cancer Prev. 15 9159-9164.
    • (2014) Asian Pac. J. Cancer Prev. , vol.15 , pp. 9159-9164
    • Majeed, H.1    Antoniou, J.2    Fang, Z.3
  • 148
    • 79960966891 scopus 로고    scopus 로고
    • Effect of micellar lipids, dietary fiber, and β-carotene on lutein bioavailability in aged rats with lutein deficiency
    • B.S. Mamatha and V. Baskaran (2011) Effect of micellar lipids, dietary fiber, and β-carotene on lutein bioavailability in aged rats with lutein deficiency. Nutrition 27 960-966.
    • (2011) Nutrition , vol.27 , pp. 960-966
    • Mamatha, B.S.1    Baskaran, V.2
  • 150
    • 70349387891 scopus 로고    scopus 로고
    • Effects of small and large molecule emulsifiers on the characteristics of β-carotene nanoemulsions prepared by high-pressure homogenization
    • L. Mao, D. Xu, J. Yang, F. Yuan, Y. Gao and J. Zhao (2009) Effects of small and large molecule emulsifiers on the characteristics of β-carotene nanoemulsions prepared by high-pressure homogenization. Food Technol. Biotechnol. 47 336-342.
    • (2009) Food Technol. Biotechnol. , vol.47 , pp. 336-342
    • Mao, L.1    Xu, D.2    Yang, J.3    Yuan, F.4    Gao, Y.5    Zhao, J.6
  • 151
    • 0036082463 scopus 로고    scopus 로고
    • Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model
    • J.F. Marier, P. Vachon, A. Gritsas, J. Zhang, J.P. Moreau and M.P. Ducharme (2002) Metabolism and disposition of resveratrol in rats: extent of absorption, glucuronidation, and enterohepatic recirculation evidenced by a linked-rat model. J. Pharmacol. Exp. Ther. 302 369-373.
    • (2002) J. Pharmacol. Exp. Ther. , vol.302 , pp. 369-373
    • Marier, J.F.1    Vachon, P.2    Gritsas, A.3    Zhang, J.4    Moreau, J.P.5    Ducharme, M.P.6
  • 152
    • 79952390166 scopus 로고    scopus 로고
    • Edible nanoemulsions: fabrication, properties, and functional performance
    • D.J. McClements (2011) Edible nanoemulsions: fabrication, properties, and functional performance. Soft Matter. 7 2297-2316.
    • (2011) Soft Matter. , vol.7 , pp. 2297-2316
    • McClements, D.J.1
  • 153
    • 84859838121 scopus 로고    scopus 로고
    • Crystals and crystallization in oil-in-water emulsions: implications for emulsion-based delivery systems
    • D.J. McClements (2012) Crystals and crystallization in oil-in-water emulsions: implications for emulsion-based delivery systems. Adv. Colloid Interf. Sci. 174 1-30.
    • (2012) Adv. Colloid Interf. Sci. , vol.174 , pp. 1-30
    • McClements, D.J.1
  • 154
    • 84880890918 scopus 로고    scopus 로고
    • Nanoemulsion-based oral delivery systems for lipophilic bioactive components: nutraceuticals and pharmaceuticals
    • D.J. McClements (2013) Nanoemulsion-based oral delivery systems for lipophilic bioactive components: nutraceuticals and pharmaceuticals. Ther. Deliv. 4 841-857.
    • (2013) Ther. Deliv. , vol.4 , pp. 841-857
    • McClements, D.J.1
  • 155
    • 84925382484 scopus 로고    scopus 로고
    • Encapsulation, protection, and release of hydrophilic active components: potential and limitations of colloidal delivery systems
    • D.J. McClements (2015) Encapsulation, protection, and release of hydrophilic active components: potential and limitations of colloidal delivery systems. Adv. Colloid Interf. Sci. 219 27-53.
    • (2015) Adv. Colloid Interf. Sci. , vol.219 , pp. 27-53
    • McClements, D.J.1
  • 156
    • 79953217389 scopus 로고    scopus 로고
    • Food-grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity
    • D.J. McClements and J. Rao (2011) Food-grade nanoemulsions: formulation, fabrication, properties, performance, biological fate, and potential toxicity. Crit. Rev. Food Sci. Nutr. 51 285-330.
    • (2011) Crit. Rev. Food Sci. Nutr. , vol.51 , pp. 285-330
    • McClements, D.J.1    Rao, J.2
  • 157
    • 84903311446 scopus 로고    scopus 로고
    • Excipient foods: designing food matrices that improve the oral bioavailability of pharmaceuticals and nutraceuticals
    • D.J. McClements and H. Xiao (2014) Excipient foods: designing food matrices that improve the oral bioavailability of pharmaceuticals and nutraceuticals. Food Funct. 5 1320-1333.
    • (2014) Food Funct. , vol.5 , pp. 1320-1333
    • McClements, D.J.1    Xiao, H.2
  • 158
    • 84926508869 scopus 로고    scopus 로고
    • The nutraceutical bioavailability classification scheme: classifying nutraceuticals according to factors limiting their oral bioavailability
    • D.J. McClements, F. Li and H. Xiao (2015) The nutraceutical bioavailability classification scheme: classifying nutraceuticals according to factors limiting their oral bioavailability. Ann. Rev. Food Sci. Technol. 6 299-327.
    • (2015) Ann. Rev. Food Sci. Technol. , vol.6 , pp. 299-327
    • McClements, D.J.1    Li, F.2    Xiao, H.3
  • 159
    • 0030912688 scopus 로고    scopus 로고
    • Antioxidant activity of the stilbene astringin, newly extracted from Vitis vinifera cell cultures
    • J.M. Mérillon, B. Fauconneau, P. Waffo, L. Barrier, J. Vercauteren and F. Huguet (1997) Antioxidant activity of the stilbene astringin, newly extracted from Vitis vinifera cell cultures. Clin. Chem. 43 1092-1093.
    • (1997) Clin. Chem. , vol.43 , pp. 1092-1093
    • Mérillon, J.M.1    Fauconneau, B.2    Waffo, P.3    Barrier, L.4    Vercauteren, J.5    Huguet, F.6
  • 161
    • 0033814457 scopus 로고    scopus 로고
    • The potential role of dietary xanthophylls in cataract and age-related macular degeneration
    • S.M. Moeller, P.F. Jacques and J.B. Blumberg (2000) The potential role of dietary xanthophylls in cataract and age-related macular degeneration. J. Am. Coll. Nutr. 19 522S-527S.
    • (2000) J. Am. Coll. Nutr. , vol.19 , pp. 522S-527S
    • Moeller, S.M.1    Jacques, P.F.2    Blumberg, J.B.3
  • 162
    • 33751334809 scopus 로고    scopus 로고
    • Medical foods: products for the management of chronic diseases
    • S.L. Morgan and J.E. Baggott (2006) Medical foods: products for the management of chronic diseases. Nutr. Rev. 64 495-501.
    • (2006) Nutr. Rev. , vol.64 , pp. 495-501
    • Morgan, S.L.1    Baggott, J.E.2
  • 163
    • 35848947928 scopus 로고    scopus 로고
    • From nutraceuticals to pharmaceuticals to nanopharmaceuticals: a case study in angiogenesis modulation during oxidative stress
    • S.A. Mousa, D.J. Bharali and D. Armstrong (2007) From nutraceuticals to pharmaceuticals to nanopharmaceuticals: a case study in angiogenesis modulation during oxidative stress. Mol. Biotechnol. 37 72-80.
    • (2007) Mol. Biotechnol. , vol.37 , pp. 72-80
    • Mousa, S.A.1    Bharali, D.J.2    Armstrong, D.3
  • 164
    • 85152829090 scopus 로고    scopus 로고
    • A lutein nanoemulsion is more effective than regular lutein in protecting cholesterol-induced liver injury by increasing lutein bioavailability in guinea pigs
    • 604.2
    • G. Murillo, S. Hu, D. Aguilar, A. Missimer, J. Smyth, S. Gannon and M.-L. Fernandez (2015) A lutein nanoemulsion is more effective than regular lutein in protecting cholesterol-induced liver injury by increasing lutein bioavailability in guinea pigs. FASEB J. 29(1 Suppl), 604.2
    • (2015) FASEB J. , vol.29 , Issue.1
    • Murillo, G.1    Hu, S.2    Aguilar, D.3    Missimer, A.4    Smyth, J.5    Gannon, S.6    Fernandez, M.-L.7
  • 166
    • 84936889017 scopus 로고    scopus 로고
    • Curcumin-loaded colloidal carrier system: formulation optimization, mechanistic insight, ex vivo and in vivo evaluation
    • Z. Naz and F.J. Ahmad (2015) Curcumin-loaded colloidal carrier system: formulation optimization, mechanistic insight, ex vivo and in vivo evaluation. Int. J. Nanomed. 10 4293-4307.
    • (2015) Int. J. Nanomed. , vol.10 , pp. 4293-4307
    • Naz, Z.1    Ahmad, F.J.2
  • 169
    • 21744447824 scopus 로고    scopus 로고
    • Resveratrol, a phenolic antioxidant with effects on blood platelet functions
    • B. Olas and B. Wachowicz (2005) Resveratrol, a phenolic antioxidant with effects on blood platelet functions. Platelets. 16 251-260.
    • (2005) Platelets. , vol.16 , pp. 251-260
    • Olas, B.1    Wachowicz, B.2
  • 170
    • 84928392364 scopus 로고    scopus 로고
    • Influence of particle size on the in vitro and in vivo antiinflammatory and antiallergic activities of a curcumin lipid nanoemulsion
    • T. Onodera, I. Kuriyama, T. Andoh, H. Ichikawa, Y. Sakamoto, E. Lee-Hiraiwa and Y. Mizushina (2015) Influence of particle size on the in vitro and in vivo antiinflammatory and antiallergic activities of a curcumin lipid nanoemulsion. Int. J. Mol. Med. 35 1720-1728.
    • (2015) Int. J. Mol. Med. , vol.35 , pp. 1720-1728
    • Onodera, T.1    Kuriyama, I.2    Andoh, T.3    Ichikawa, H.4    Sakamoto, Y.5    Lee-Hiraiwa, E.6    Mizushina, Y.7
  • 172
    • 33644854620 scopus 로고    scopus 로고
    • Comparative studies of the antioxidant effects of cis- and trans resveratrol
    • F. Orallo (2006) Comparative studies of the antioxidant effects of cis- and trans resveratrol. Curr. Med. Chem. 13 87-98.
    • (2006) Curr. Med. Chem. , vol.13 , pp. 87-98
    • Orallo, F.1
  • 173
    • 84903613988 scopus 로고    scopus 로고
    • Formation and stabilization of nanoemulsion-based vitamin E delivery systems using natural surfactants: Quillaja saponin and lecithin
    • B. Ozturk, S. Argin, M. Ozilgen and D.J. McClements (2014) Formation and stabilization of nanoemulsion-based vitamin E delivery systems using natural surfactants: Quillaja saponin and lecithin. J. Food Eng. 124 57-63.
    • (2014) J. Food Eng. , vol.124 , pp. 57-63
    • Ozturk, B.1    Argin, S.2    Ozilgen, M.3    McClements, D.J.4
  • 174
    • 84928978793 scopus 로고    scopus 로고
    • Formation and stabilization of nanoemulsion-based vitamin E delivery systems using natural biopolymers: whey protein isolate and gum arabic
    • B. Ozturk, S. Argin, M. Ozilgen and D.J. McClements (2015) Formation and stabilization of nanoemulsion-based vitamin E delivery systems using natural biopolymers: whey protein isolate and gum arabic. Food Chem. 188 256-263.
    • (2015) Food Chem. , vol.188 , pp. 256-263
    • Ozturk, B.1    Argin, S.2    Ozilgen, M.3    McClements, D.J.4
  • 175
    • 0032926620 scopus 로고
    • Biotransformation of curcumin through reduction and glucuronidation in mice
    • M.H. Pan, T.M. Huang and J.K. Lin (1992) Biotransformation of curcumin through reduction and glucuronidation in mice. Drug Metab. Dispos. 27 486-494.
    • (1992) Drug Metab. Dispos. , vol.27 , pp. 486-494
    • Pan, M.H.1    Huang, T.M.2    Lin, J.K.3
  • 177
    • 84910637461 scopus 로고    scopus 로고
    • Vitamin E loaded resveratrol nanoemulsion for brain targeting for the treatment o’ Parkinson’s disease by reducing oxidative stress
    • R. Pangeni, S. Sharma, G. Mustafa, J. Ali and S. Baboota (2014) Vitamin E loaded resveratrol nanoemulsion for brain targeting for the treatment o’ Parkinson’s disease by reducing oxidative stress. Nanotechnology 25(48), 485102.
    • (2014) Nanotechnology , vol.25 , Issue.48 , pp. 485102
    • Pangeni, R.1    Sharma, S.2    Mustafa, G.3    Ali, J.4    Baboota, S.5
  • 180
    • 84879989083 scopus 로고    scopus 로고
    • Novel lipid based systems for improved topical delivery of antioxidants
    • A. Pol and V. Patravale (2009) Novel lipid based systems for improved topical delivery of antioxidants. Househ. Pers. Care Today. 4 5-8.
    • (2009) Househ. Pers. Care Today. , vol.4 , pp. 5-8
    • Pol, A.1    Patravale, V.2
  • 181
    • 84871732168 scopus 로고    scopus 로고
    • Encapsulation and release of hydrophobic bioactive components in nanoemulsion-based delivery systems: impact of physical form on quercetin bioaccessibility
    • H. Pool, S. Mendoza, H. Xiao and D.J. McClements (2013) Encapsulation and release of hydrophobic bioactive components in nanoemulsion-based delivery systems: impact of physical form on quercetin bioaccessibility. Food Funct. 4 162-174.
    • (2013) Food Funct. , vol.4 , pp. 162-174
    • Pool, H.1    Mendoza, S.2    Xiao, H.3    McClements, D.J.4
  • 182
    • 39149092022 scopus 로고    scopus 로고
    • Enhancing intestinal drug solubilisation using lipid-based delivery systems
    • C.J.H. Porter, C.W. Pouton, J.F. Cuine and W.N. Charman (2008) Enhancing intestinal drug solubilisation using lipid-based delivery systems. Adv. Drug Deliv. Rev. 60 673-691.
    • (2008) Adv. Drug Deliv. Rev. , vol.60 , pp. 673-691
    • Porter, C.J.H.1    Pouton, C.W.2    Cuine, J.F.3    Charman, W.N.4
  • 183
    • 33751014029 scopus 로고    scopus 로고
    • Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system
    • C.W. Pouton (2006) Formulation of poorly water-soluble drugs for oral administration: physicochemical and physiological issues and the lipid formulation classification system. Eur. J. Pharm. Sci. 29 278-287.
    • (2006) Eur. J. Pharm. Sci. , vol.29 , pp. 278-287
    • Pouton, C.W.1
  • 184
    • 39149113817 scopus 로고    scopus 로고
    • Formulation of lipid-based delivery systems for oral administration: materials, methods, and strategies
    • C.W. Pouton and C.J.H. Porter (2008) Formulation of lipid-based delivery systems for oral administration: materials, methods, and strategies. Adv. Drug Deliver. Rev. 60 625-637.
    • (2008) Adv. Drug Deliver. Rev. , vol.60 , pp. 625-637
    • Pouton, C.W.1    Porter, C.J.H.2
  • 185
    • 84921535683 scopus 로고    scopus 로고
    • Curcumin, a component of golden spice: From bedside to bench and back
    • S. Prasad, S.C. Gupta, A.K. Tyagi and B.B. Aggarwal (2014) Curcumin, a component of golden spice: From bedside to bench and back. Biotechnol. Adv. 32 1053-1064.
    • (2014) Biotechnol. Adv. , vol.32 , pp. 1053-1064
    • Prasad, S.1    Gupta, S.C.2    Tyagi, A.K.3    Aggarwal, B.B.4
  • 186
    • 84901759449 scopus 로고    scopus 로고
    • Lipid-based nanoemulsifying resveratrol for improved physicochemical characteristics, in vitro cytotoxicity and in vivo antiangiogenic efficacy
    • S. Pund, R. Thankur, U. More and A. Joshi (2014) Lipid-based nanoemulsifying resveratrol for improved physicochemical characteristics, in vitro cytotoxicity and in vivo antiangiogenic efficacy. Colloid. Surf. B 120 110-117.
    • (2014) Colloid. Surf. B , vol.120 , pp. 110-117
    • Pund, S.1    Thankur, R.2    More, U.3    Joshi, A.4
  • 187
    • 84896493964 scopus 로고    scopus 로고
    • Improvement of antiinflammatory and antiangiogenic activity of berberine by novel rapid dissolving nanoemulsifying technique
    • S. Pund, G. Borade and G. Rasve (2014) Improvement of antiinflammatory and antiangiogenic activity of berberine by novel rapid dissolving nanoemulsifying technique. Phytomedicine 21 307-314.
    • (2014) Phytomedicine , vol.21 , pp. 307-314
    • Pund, S.1    Borade, G.2    Rasve, G.3
  • 188
    • 79952534865 scopus 로고    scopus 로고
    • Formation of nanoemulsions stabilized by model food-grade emulsifiers using high-pressure homogenization: factors affecting particle size
    • C. Qian and D.J. McClements (2011) Formation of nanoemulsions stabilized by model food-grade emulsifiers using high-pressure homogenization: factors affecting particle size. Food Hydrocoll. 25 1000-1008.
    • (2011) Food Hydrocoll. , vol.25 , pp. 1000-1008
    • Qian, C.1    McClements, D.J.2
  • 189
    • 84856212477 scopus 로고    scopus 로고
    • Physical and chemical stability of β-carotene-enriched nanoemulsions: influence of pH, ionic strength, temperature, and emulsifier type
    • C. Qian, E.A. Decker, H. Xiao and D.J. McClements (2012) Physical and chemical stability of β-carotene-enriched nanoemulsions: influence of pH, ionic strength, temperature, and emulsifier type. Food Chem. 132 1221-1229.
    • (2012) Food Chem. , vol.132 , pp. 1221-1229
    • Qian, C.1    Decker, E.A.2    Xiao, H.3    McClements, D.J.4
  • 190
    • 84929075615 scopus 로고    scopus 로고
    • Curcumin nanoemulsion for transdermal application: formulation and evaluation
    • H. Rachmawati, D.K. Budiputra and R. Mauludin (2015) Curcumin nanoemulsion for transdermal application: formulation and evaluation. Drug Dev. Ind. Pharm. 41 560-566.
    • (2015) Drug Dev. Ind. Pharm. , vol.41 , pp. 560-566
    • Rachmawati, H.1    Budiputra, D.K.2    Mauludin, R.3
  • 191
    • 84922450766 scopus 로고    scopus 로고
    • Dietary lutein modulates growth and survival genes in prostate cancer cells
    • M.M. Rafi, S. Kanakasabai, S.V. Gokarn, E.G. Krueger and J.J. Bright (2015) Dietary lutein modulates growth and survival genes in prostate cancer cells. J. Med. Food 18 173-181.
    • (2015) J. Med. Food , vol.18 , pp. 173-181
    • Rafi, M.M.1    Kanakasabai, S.2    Gokarn, S.V.3    Krueger, E.G.4    Bright, J.J.5
  • 194
    • 43749083033 scopus 로고    scopus 로고
    • Structural behaviour of lipid droplets in protein-stabilized nano-emulsions and st–bility of -tocopherol
    • P. Relkin, J.-M. Yung, D. Kalnin and M. Ollivon (2008) Structural behaviour of lipid droplets in protein-stabilized nano-emulsions and st–bility of -tocopherol. Food Biophysics. 3 163-168.
    • (2008) Food Biophysics. , vol.3 , pp. 163-168
    • Relkin, P.1    Yung, J.-M.2    Kalnin, D.3    Ollivon, M.4
  • 195
    • 43049183607 scopus 로고    scopus 로고
    • Natural products as a robust source of new drugs and drug leads: past successes and present day issues
    • G.M. Rishton (2008) Natural products as a robust source of new drugs and drug leads: past successes and present day issues. Am. J. Cardiol. 101 43D-49D.
    • (2008) Am. J. Cardiol. , vol.101 , pp. 43D-49D
    • Rishton, G.M.1
  • 196
    • 84897003566 scopus 로고    scopus 로고
    • Recent progress in tight junction modulation for improving bioavailability
    • D. Saaber, S. Wollenhaupt, K. Baumann and S. Reichl (2014) Recent progress in tight junction modulation for improving bioavailability. Expert Opin. Drug Discov. 9 367-381.
    • (2014) Expert Opin. Drug Discov. , vol.9 , pp. 367-381
    • Saaber, D.1    Wollenhaupt, S.2    Baumann, K.3    Reichl, S.4
  • 197
    • 84868670720 scopus 로고    scopus 로고
    • Fabrication of vitamin E-enriched nanoemulsions: factors affecting particle size using spontaneous emulsification
    • A.H. Saberi, Y. Fang and D.J. McClements (2013) Fabrication of vitamin E-enriched nanoemulsions: factors affecting particle size using spontaneous emulsification. J. Colloid Interf. Sci. 391 95-102.
    • (2013) J. Colloid Interf. Sci. , vol.391 , pp. 95-102
    • Saberi, A.H.1    Fang, Y.2    McClements, D.J.3
  • 198
  • 200
    • 33746716790 scopus 로고    scopus 로고
    • Nanoscale materials development: a food industry perspective
    • P. Sanguansri and M.A. Augustin (2006) Nanoscale materials development: a food industry perspective. Trend. Food Sci. Technol. 17 547-556.
    • (2006) Trend. Food Sci. Technol. , vol.17 , pp. 547-556
    • Sanguansri, P.1    Augustin, M.A.2
  • 202
    • 53949090765 scopus 로고    scopus 로고
    • NF-kappa signaling pathway and its therapeutic implications in human diseases
    • S.H. Sarkar, Y. Li, Z. Wang and D. Kong (2008) NF-kappa signaling pathway and its therapeutic implications in human diseases. Int. Rev. Immunol. 27 293-319.
    • (2008) Int. Rev. Immunol. , vol.27 , pp. 293-319
    • Sarkar, S.H.1    Li, Y.2    Wang, Z.3    Kong, D.4
  • 204
    • 84914815494 scopus 로고    scopus 로고
    • A self-microemulsifying drug delivery system to overcome intestinal resveratrol toxicity and presystemic metabolism
    • K.B. Seljak, K. Berginc, J. Trontelj, A. Zvonar, A. Kristl and M. Gašperlin (2014) A self-microemulsifying drug delivery system to overcome intestinal resveratrol toxicity and presystemic metabolism. J. Pharm. Sci. 103(11), 3491-3500.
    • (2014) J. Pharm. Sci. , vol.103 , Issue.11 , pp. 3491-3500
    • Seljak, K.B.1    Berginc, K.2    Trontelj, J.3    Zvonar, A.4    Kristl, A.5    Gašperlin, M.6
  • 205
    • 83055165711 scopus 로고    scopus 로고
    • Evaluation of the stability and antioxidant activity of nanoencapsulated resveratrol during in vitro digestion
    • M. Sessa, R. Tsao, R.H. Liu, G. Ferrari and F. Donsì (2011) Evaluation of the stability and antioxidant activity of nanoencapsulated resveratrol during in vitro digestion. J. Agric. Food Chem. 59 12352-12360.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 12352-12360
    • Sessa, M.1    Tsao, R.2    Liu, R.H.3    Ferrari, G.4    Donsì, F.5
  • 208
    • 84961683020 scopus 로고    scopus 로고
    • Nanotechnology: a successful approach to improve oral bioavailability of phytochemicals
    • A. Shakeri and A. Sahebkar (2016) Nanotechnology: a successful approach to improve oral bioavailability of phytochemicals. Recent Pat. Drug Deliv. Formul. 10 4-6.
    • (2016) Recent Pat. Drug Deliv. Formul. , vol.10 , pp. 4-6
    • Shakeri, A.1    Sahebkar, A.2
  • 209
    • 79957521117 scopus 로고    scopus 로고
    • Enhanced bioavailability and retinal accumulation of lutein from self-emulsifying phospholipid suspension (SEPS)
    • S. Shanmugam, J.H. Park, K.S. Kim, Z.Z. Piao, C.S. Yong, H.G. Choi and J.S. Woo (2011) Enhanced bioavailability and retinal accumulation of lutein from self-emulsifying phospholipid suspension (SEPS). Int. J. Pharm. 412 99-105.
    • (2011) Int. J. Pharm. , vol.412 , pp. 99-105
    • Shanmugam, S.1    Park, J.H.2    Kim, K.S.3    Piao, Z.Z.4    Yong, C.S.5    Choi, H.G.6    Woo, J.S.7
  • 210
    • 84933504702 scopus 로고    scopus 로고
    • Effect of high-pressure homogenization on formulation of TPGS loaded nanoemulsion of rutin - pharmacodynamic and antioxidant studies
    • S. Sharma, J.K. Sahni, J. Ali and S. Baboota (2015) Effect of high-pressure homogenization on formulation of TPGS loaded nanoemulsion of rutin - pharmacodynamic and antioxidant studies. Drug Deliv. 22 541-551.
    • (2015) Drug Deliv. , vol.22 , pp. 541-551
    • Sharma, S.1    Sahni, J.K.2    Ali, J.3    Baboota, S.4
  • 211
    • 84865316619 scopus 로고    scopus 로고
    • Carotenoid lutein: a promising candidate for pharmaceutical and nutraceutical applications
    • R. Shegokar and K. Mitri (2012) Carotenoid lutein: a promising candidate for pharmaceutical and nutraceutical applications. J. Dietary Suppl. 9 183-210.
    • (2012) J. Dietary Suppl. , vol.9 , pp. 183-210
    • Shegokar, R.1    Mitri, K.2
  • 212
    • 77956863976 scopus 로고    scopus 로고
    • Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials
    • A. Shehzad, F. Wahid and Y.S. Lee (2010) Curcumin in cancer chemoprevention: molecular targets, pharmacokinetics, bioavailability, and clinical trials. Arch. Pharm. Chem. Life Sci. 9 489-499.
    • (2010) Arch. Pharm. Chem. Life Sci. , vol.9 , pp. 489-499
    • Shehzad, A.1    Wahid, F.2    Lee, Y.S.3
  • 213
    • 0034527660 scopus 로고    scopus 로고
    • Lycopene in tomatoes: chemical and physical properties affected by food processing
    • J. Shi and M. Le Maguer (2000) Lycopene in tomatoes: chemical and physical properties affected by food processing. Crit. Rev. Biotechnol. 20 293-334.
    • (2000) Crit. Rev. Biotechnol. , vol.20 , pp. 293-334
    • Shi, J.1    Le Maguer, M.2
  • 216
  • 219
    • 84857999664 scopus 로고    scopus 로고
    • Nanoemulsions for food applications: development and characterization
    • H.D. Silva, M.A. Cerqueira and A.A. Vicente (2012) Nanoemulsions for food applications: development and characterization. Food Bioprocess. Technol. 5 854-867.
    • (2012) Food Bioprocess. Technol. , vol.5 , pp. 854-867
    • Silva, H.D.1    Cerqueira, M.A.2    Vicente, A.A.3
  • 220
    • 84878465785 scopus 로고    scopus 로고
    • Carotenoid lutein protects the kidney against cisplatin-induced acute renal failure
    • E.R. Sindhu and R. Kuttan (2013) Carotenoid lutein protects the kidney against cisplatin-induced acute renal failure. J. Environ. Pathol. Toxicol. Oncol. 32 21-28.
    • (2013) J. Environ. Pathol. Toxicol. Oncol. , vol.32 , pp. 21-28
    • Sindhu, E.R.1    Kuttan, R.2
  • 221
    • 77954904046 scopus 로고    scopus 로고
    • Carotenoid lutein protects rats from paracetamol-, carbon tetrachloride-, and ethanol-induced hepatic damage
    • E.R. Sindhu, A.P. Firdous, K.C. Preethi and R. Kuttan (2010) Carotenoid lutein protects rats from paracetamol-, carbon tetrachloride-, and ethanol-induced hepatic damage. J. Pharm. Pharmacol. 62 1054-1060.
    • (2010) J. Pharm. Pharmacol. , vol.62 , pp. 1054-1060
    • Sindhu, E.R.1    Firdous, A.P.2    Preethi, K.C.3    Kuttan, R.4
  • 222
    • 84876730531 scopus 로고    scopus 로고
    • Antimutagenic activity of lutein: an oxycarotenoid present in the macula and its inhibition of cytochrome 450 enzymes in vitro
    • E.R. Sindhu, A.P. Firdous, R. Viswanathan and R. Kuttan (2012) Antimutagenic activity of lutein: an oxycarotenoid present in the macula and its inhibition of cytochrome 450 enzymes in vitro. Drug Metab. Lett. 6 213-220.
    • (2012) Drug Metab. Lett. , vol.6 , pp. 213-220
    • Sindhu, E.R.1    Firdous, A.P.2    Viswanathan, R.3    Kuttan, R.4
  • 223
    • 84964336256 scopus 로고    scopus 로고
    • In vitro and in vivo performance of supersaturable self-nanoemulsifying system of trans-resveratrol
    • G. Singh and R.S. Pai (2016) In vitro and in vivo performance of supersaturable self-nanoemulsifying system of trans-resveratrol. Artif. Cells Nanomed. Biotechnol. 44(2), 510-516.
    • (2016) Artif. Cells Nanomed. Biotechnol. , vol.44 , Issue.2 , pp. 510-516
    • Singh, G.1    Pai, R.S.2
  • 224
    • 76849109564 scopus 로고    scopus 로고
    • Self-emulsifying drug delivery systems (SEDDS): formulation development, characterization, and applications
    • B. Singh, S. Bandopadhyay, R. Kapil, R. Singh and O.P. Katare (2009) Self-emulsifying drug delivery systems (SEDDS): formulation development, characterization, and applications. Cri. Rev. Ther. Drug Carrier Syst. 26 427-521.
    • (2009) Cri. Rev. Ther. Drug Carrier Syst. , vol.26 , pp. 427-521
    • Singh, B.1    Bandopadhyay, S.2    Kapil, R.3    Singh, R.4    Katare, O.P.5
  • 226
    • 84885227307 scopus 로고    scopus 로고
    • Optimization of curcumin nanoemulsion for intranasal delivery using design of experiment and its toxicity assessment
    • S. Sood, K. Jain and K. Gowthamarajan (2014) Optimization of curcumin nanoemulsion for intranasal delivery using design of experiment and its toxicity assessment. Colloid. Surf. B 113 330-337.
    • (2014) Colloid. Surf. B , vol.113 , pp. 330-337
    • Sood, S.1    Jain, K.2    Gowthamarajan, K.3
  • 227
    • 17044424117 scopus 로고    scopus 로고
    • Role of spices beyond food flavoring: nutraceuticals with multiple health effects
    • K. Srinivasan (2005) Role of spices beyond food flavoring: nutraceuticals with multiple health effects. Food Rev. Int. 21 167-188.
    • (2005) Food Rev. Int. , vol.21 , pp. 167-188
    • Srinivasan, K.1
  • 228
    • 84921067553 scopus 로고    scopus 로고
    • Lycopene; chemistry, biosynthesis, metabolism, and degradation under various abiotic parameters
    • S. Srivastava and A.K. Srivastava (2013) Lycopene; chemistry, biosynthesis, metabolism, and degradation under various abiotic parameters. J. Food Sci. Technol. 52 41-53.
    • (2013) J. Food Sci. Technol. , vol.52 , pp. 41-53
    • Srivastava, S.1    Srivastava, A.K.2
  • 229
    • 13844280519 scopus 로고    scopus 로고
    • Dietary lutein and zeaxanthin: possible effects on visual function
    • J.M. Stringham and B.R. Hammond (2005) Dietary lutein and zeaxanthin: possible effects on visual function. Nutr. Rev. 63 59-64.
    • (2005) Nutr. Rev. , vol.63 , pp. 59-64
    • Stringham, J.M.1    Hammond, B.R.2
  • 231
    • 84862248921 scopus 로고    scopus 로고
    • Cancer cell signaling pathways targeted by spice-derived nutraceuticals
    • B. Sung, S. Prasad, V.R. Yadav and B.B. Aggarwal (2012) Cancer cell signaling pathways targeted by spice-derived nutraceuticals. Nutr. Cancer 64 173-197.
    • (2012) Nutr. Cancer , vol.64 , pp. 173-197
    • Sung, B.1    Prasad, S.2    Yadav, V.R.3    Aggarwal, B.B.4
  • 232
    • 84906964408 scopus 로고    scopus 로고
    • Stability indicating HPLC–UV method for detection of curcumin in Curcuma longa extract and emulsion formulation
    • H.K. Syed, K.B. Liew, G.O.K. Loh and K.K. Peh (2015) Stability indicating HPLC–UV method for detection of curcumin in Curcuma longa extract and emulsion formulation. Food Chem. 170 321-326.
    • (2015) Food Chem. , vol.170 , pp. 321-326
    • Syed, H.K.1    Liew, K.B.2    Loh, G.O.K.3    Peh, K.K.4
  • 233
    • 84913555860 scopus 로고    scopus 로고
    • Natural products in medicine: transformational outcome of synthetic chemistry
    • J. Szychowski, J.F. Truchon and Y.L. Bennani (2014) Natural products in medicine: transformational outcome of synthetic chemistry. J. Med. Chem. 57 9292-9308.
    • (2014) J. Med. Chem. , vol.57 , pp. 9292-9308
    • Szychowski, J.1    Truchon, J.F.2    Bennani, Y.L.3
  • 235
    • 17444411558 scopus 로고    scopus 로고
    • β-carotene nanodispersions: preparation, characterization, and stability evaluation
    • C.P. Tan and M. Nakajima (2005) β-carotene nanodispersions: preparation, characterization, and stability evaluation. Food Chem. 92 661-671.
    • (2005) Food Chem. , vol.92 , pp. 661-671
    • Tan, C.P.1    Nakajima, M.2
  • 236
    • 77950535301 scopus 로고    scopus 로고
    • A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals
    • Teo, B.S.X., Basri, M., Zakaria, M.R.S., Salleh, A.B., Rahman, R.N.Z.R.A., Rahman, M.B.A., 2010. A potential tocopherol acetate loaded palm oil esters-in-water nanoemulsions for nanocosmeceuticals. J. Nanobiotechnol. 8:4. www.jnanobiotechnology.com/content/8/1/4
    • (2010) J. Nanobiotechnol. , vol.8 , pp. 4
    • Teo, B.S.X.1    Basri, M.2    Zakaria, M.R.S.3    Salleh, A.B.4    Rahman, R.N.Z.R.A.5    Rahman, M.B.A.6
  • 237
    • 52949116438 scopus 로고    scopus 로고
    • Improvement of the oral bioavailability of coenzyme Q10 by emulsification with fats and emulsifiers used in the food industry
    • P. Thanatuksorn, K. Kawai, M. Hayakawa, M. Hayashi and K. Kajiwara (2009) Improvement of the oral bioavailability of coenzyme Q10 by emulsification with fats and emulsifiers used in the food industry. Food Sci. Technol. 42 385-390.
    • (2009) Food Sci. Technol. , vol.42 , pp. 385-390
    • Thanatuksorn, P.1    Kawai, K.2    Hayakawa, M.3    Hayashi, M.4    Kajiwara, K.5
  • 238
    • 84898053516 scopus 로고    scopus 로고
    • Common delivery systems for enhancing in vivo bioavailability and biological efficacy of nutraceuticals
    • Y. Ting, Y. Jiang, C.-T. Ho and Q. Huang (2014) Common delivery systems for enhancing in vivo bioavailability and biological efficacy of nutraceuticals. J. Funct. Food 7 112-128.
    • (2014) J. Funct. Food , vol.7 , pp. 112-128
    • Ting, Y.1    Jiang, Y.2    Ho, C.-T.3    Huang, Q.4
  • 239
    • 84894442838 scopus 로고    scopus 로고
    • Quercetin-containing self-nanoemulsifying drug delivery system for improving oral bioavailability
    • T.H. Tran, Y. Guo, D. Song, R.E. Bruno and X. Lu (2014) Quercetin-containing self-nanoemulsifying drug delivery system for improving oral bioavailability. J. Pharm. Sci. 103 840-852.
    • (2014) J. Pharm. Sci. , vol.103 , pp. 840-852
    • Tran, T.H.1    Guo, Y.2    Song, D.3    Bruno, R.E.4    Lu, X.5
  • 240
    • 0001269795 scopus 로고    scopus 로고
    • Resveratrol: isomeric molar absorptivities and stability
    • B.C. Trela and A.L. Waterhouse (1996) Resveratrol: isomeric molar absorptivities and stability. J. Agric. Food Chem. 44 1253-1257.
    • (1996) J. Agric. Food Chem. , vol.44 , pp. 1253-1257
    • Trela, B.C.1    Waterhouse, A.L.2
  • 242
    • 84922360438 scopus 로고    scopus 로고
    • Preparation and evaluation of submicron-carriers for naringenin topical application
    • M.J. Tsai, Y.B. Huang, J.W. Fang, Y.S. Fu and P.C. Wuc (2015) Preparation and evaluation of submicron-carriers for naringenin topical application. Int. J. Pharm. 481 84-90.
    • (2015) Int. J. Pharm. , vol.481 , pp. 84-90
    • Tsai, M.J.1    Huang, Y.B.2    Fang, J.W.3    Fu, Y.S.4    Wuc, P.C.5
  • 243
    • 0029782485 scopus 로고    scopus 로고
    • Carrier-mediated intestinal transport of drugs
    • A. Tsuji and I. Tamai (1996) Carrier-mediated intestinal transport of drugs. Pharm. Res. 13 963-977.
    • (1996) Pharm. Res. , vol.13 , pp. 963-977
    • Tsuji, A.1    Tamai, I.2
  • 244
    • 85077645705 scopus 로고    scopus 로고
    • Characterization and stability evaluation of thymoquinone nanoemulsions prepared by high-pressure homogenization
    • Article ID 453290
    • Z. Tubesha, Z.A. Bakar and M. Ismail (2013) Characterization and stability evaluation of thymoquinone nanoemulsions prepared by high-pressure homogenization. J. Nanomat. 6 Article ID 453290
    • (2013) J. Nanomat. , vol.6
    • Tubesha, Z.1    Bakar, Z.A.2    Ismail, M.3
  • 245
    • 84889634274 scopus 로고    scopus 로고
    • Characterization of CurcuEmulsomes: nanoformulation for enhanced solubility and delivery of curcumin
    • M.H. Ucisik, S. Küpcü, B. Schuster and U.B. Sleytr (2013) Characterization of CurcuEmulsomes: nanoformulation for enhanced solubility and delivery of curcumin. J. Nanobiotechnol. 11 1-13.
    • (2013) J. Nanobiotechnol. , vol.11 , pp. 1-13
    • Ucisik, M.H.1    Küpcü, S.2    Schuster, B.3    Sleytr, U.B.4
  • 247
    • 0034003010 scopus 로고    scopus 로고
    • Isolation and identification of stilbenes in two varieties of Polygonum cuspidatum
    • B.C. Vastano, Y. Chen, N. Zhu, C.T. Ho, Z. Zhou and R.T. Rosen (2000) Isolation and identification of stilbenes in two varieties of Polygonum cuspidatum. J. Agric. Food Chem. 48 253-256.
    • (2000) J. Agric. Food Chem. , vol.48 , pp. 253-256
    • Vastano, B.C.1    Chen, Y.2    Zhu, N.3    Ho, C.T.4    Zhou, Z.5    Rosen, R.T.6
  • 249
  • 250
    • 79953204843 scopus 로고    scopus 로고
    • Bioavailability of a nanoemulsion of lutein is greater than a lutein supplement
    • R. Vishwanathan, T.A. Wilson and R.J. Nicolosi (2009) Bioavailability of a nanoemulsion of lutein is greater than a lutein supplement. Nano Biomed. Eng. 1 38-49.
    • (2009) Nano Biomed. Eng. , vol.1 , pp. 38-49
    • Vishwanathan, R.1    Wilson, T.A.2    Nicolosi, R.J.3
  • 251
    • 85152828919 scopus 로고    scopus 로고
    • Lutein uptake is greater from egg yolks compared to nanoemulsions in Caco-2 cells
    • 975.22
    • R. Vishwanathan, T. Wilson and R. Nicolosi (2011) Lutein uptake is greater from egg yolks compared to nanoemulsions in Caco-2 cells. FASEB J. 25 975.22
    • (2011) FASEB J. , vol.25
    • Vishwanathan, R.1    Wilson, T.2    Nicolosi, R.3
  • 253
    • 85152850472 scopus 로고    scopus 로고
    • The future of nutraceuticals
    • Wagner, J., (Ed.).
    • Wagner, J. (Ed.). 2002. The future of nutraceuticals. Nutritional Outlook Magazine, June/July. http://www.fimdefelice.org/p2420.html.
    • (2002) Nutritional Outlook Magazine, June/July.
  • 254
    • 0026791626 scopus 로고
    • Principles of emulsion formation
    • P. Walstra (1993) Principles of emulsion formation. Chem. Eng. Sci. 48 333.
    • (1993) Chem. Eng. Sci. , vol.48 , pp. 333
    • Walstra, P.1
  • 255
    • 84867822382 scopus 로고    scopus 로고
    • Lycopene metabolism and its biological significance
    • X.-D. Wang (2012) Lycopene metabolism and its biological significance. Am. J. Clin. Nutr. 96 1214S-1222S.
    • (2012) Am. J. Clin. Nutr. , vol.96 , pp. 1214S-1222S
    • Wang, X.-D.1
  • 256
    • 38049067071 scopus 로고    scopus 로고
    • Enhancing antiinflammation activity of curcumin through O/W nanoemulsions
    • X. Wang, Y. Jiang, Y.W. Wang, M.T. Huang, C.T. Hoa and Q. Huang (2008) Enhancing antiinflammation activity of curcumin through O/W nanoemulsions. Food Chem. 108 419-424.
    • (2008) Food Chem. , vol.108 , pp. 419-424
    • Wang, X.1    Jiang, Y.2    Wang, Y.W.3    Huang, M.T.4    Hoa, C.T.5    Huang, Q.6
  • 257
    • 84898001283 scopus 로고    scopus 로고
    • Specific carotenoid intake is inversely associated with the risk of breast cancer among Chinese women
    • L. Wang, B. Li, M.X. Pan, X.F. Mo, Y.M. Chen and C.X. Zhang (2014) Specific carotenoid intake is inversely associated with the risk of breast cancer among Chinese women. Br. J. Nutr. 111 1686-1695.
    • (2014) Br. J. Nutr. , vol.111 , pp. 1686-1695
    • Wang, L.1    Li, B.2    Pan, M.X.3    Mo, X.F.4    Chen, Y.M.5    Zhang, C.X.6
  • 258
    • 84857356952 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of silybin by a supersaturatable self-emulsifying drug delivery system (S-SEDDS)
    • Y. Wei, X. Ye, X. Shang, X. Peng, Q. Bao, M. Liu, M. Guo and F. Li (2012) Enhanced oral bioavailability of silybin by a supersaturatable self-emulsifying drug delivery system (S-SEDDS). Colloid. Surf. A. 396 22-28.
    • (2012) Colloid. Surf. A. , vol.396 , pp. 22-28
    • Wei, Y.1    Ye, X.2    Shang, X.3    Peng, X.4    Bao, Q.5    Liu, M.6    Guo, M.7    Li, F.8
  • 259
    • 20344364428 scopus 로고    scopus 로고
    • Metabolism and bioavailability of trans-resveratrol
    • E. Wenzel and V. Somoza (2005) Metabolism and bioavailability of trans-resveratrol. Mol. Nutr. Food Res. 49 472-481.
    • (2005) Mol. Nutr. Food Res. , vol.49 , pp. 472-481
    • Wenzel, E.1    Somoza, V.2
  • 260
    • 79551639050 scopus 로고    scopus 로고
    • Curcumin: A review of anticancer properties and therapeutic activity in head and neck squamous cell carcinoma
    • R. Wilken, M.S. Veena, M.B. Wang and E.S. Srivatsan (2011) Curcumin: A review of anticancer properties and therapeutic activity in head and neck squamous cell carcinoma. Mol. Cancer. 10 1-19.
    • (2011) Mol. Cancer. , vol.10 , pp. 1-19
    • Wilken, R.1    Veena, M.S.2    Wang, M.B.3    Srivatsan, E.S.4
  • 261
    • 78650024236 scopus 로고    scopus 로고
    • Self-microemulsifying drug delivery system improves curcumin dissolution and bioavailability
    • X. Wu, J. Xu, X. Huang and C. Wen (2011) Self-microemulsifying drug delivery system improves curcumin dissolution and bioavailability. Drug Dev. Ind. Pharm. 37 15-23.
    • (2011) Drug Dev. Ind. Pharm. , vol.37 , pp. 15-23
    • Wu, X.1    Xu, J.2    Huang, X.3    Wen, C.4
  • 262
    • 34548238320 scopus 로고    scopus 로고
    • Chitosan as a lipid binder: a Langmuir monolayer study of chitosan-lipid interactions
    • P. Wydro, B. Krajewska and K. Hac-Wydro (2007) Chitosan as a lipid binder: a Langmuir monolayer study of chitosan-lipid interactions. Biomacromolecules. 8 2611-2617.
    • (2007) Biomacromolecules. , vol.8 , pp. 2611-2617
    • Wydro, P.1    Krajewska, B.2    Hac-Wydro, K.3
  • 263
    • 67549123935 scopus 로고    scopus 로고
    • Formulation development and bioavailability evaluation of a self-nanoemulsified drug delivery system of oleanolic acid
    • J. Xi, Q. Chang, C.K. Chang, Z.Y. Meng, G.N. Wang, J.B. Sun, Y.T. Wang, H.H. Tong and Y. Zheng (2009) Formulation development and bioavailability evaluation of a self-nanoemulsified drug delivery system of oleanolic acid. AAPS PharmSciTech. 10 172-182.
    • (2009) AAPS PharmSciTech. , vol.10 , pp. 172-182
    • Xi, J.1    Chang, Q.2    Chang, C.K.3    Meng, Z.Y.4    Wang, G.N.5    Sun, J.B.6    Wang, Y.T.7    Tong, H.H.8    Zheng, Y.9
  • 264
    • 84855837427 scopus 로고    scopus 로고
    • Curcumin nanoformulations: a future nanomedicine for cancer
    • M.M. Yallapu, M. Jaggi and S.C. Chauhan (2012) Curcumin nanoformulations: a future nanomedicine for cancer. Drug Discov. Today. 17 71-80.
    • (2012) Drug Discov. Today. , vol.17 , pp. 71-80
    • Yallapu, M.M.1    Jaggi, M.2    Chauhan, S.C.3
  • 265
    • 80051519201 scopus 로고    scopus 로고
    • Enhanced oral bioavailability of curcumin via a solid lipid-based self-emulsifying drug delivery system using a spray-drying technique
    • Y.D. Yan, J.A. Kim, M.K. Kwak, B.K. Yoo, C.S. Yong and H.G. Choi (2011) Enhanced oral bioavailability of curcumin via a solid lipid-based self-emulsifying drug delivery system using a spray-drying technique. Biol. Pharm. Bull. 34 1179-1186.
    • (2011) Biol. Pharm. Bull. , vol.34 , pp. 1179-1186
    • Yan, Y.D.1    Kim, J.A.2    Kwak, M.K.3    Yoo, B.K.4    Yong, C.S.5    Choi, H.G.6
  • 266
    • 84861134341 scopus 로고    scopus 로고
    • Fabrication of ultrafine edible emulsions: comparison of high-energy and low-energy homogenization methods
    • Y. Yang, C. Marshall-Breton, M.E. Leser, A.A. Sher and D.J. McClements (2012) Fabrication of ultrafine edible emulsions: comparison of high-energy and low-energy homogenization methods. Food Hydrocolloid. 29 398-406.
    • (2012) Food Hydrocolloid. , vol.29 , pp. 398-406
    • Yang, Y.1    Marshall-Breton, C.2    Leser, M.E.3    Sher, A.A.4    McClements, D.J.5
  • 267
    • 84897727791 scopus 로고    scopus 로고
    • Delivery of lipophilic bioactives: assembly, disassembly, and reassembly of lipid nanoparticles
    • M. Yao, H. Xio and D.J. McClements (2014) Delivery of lipophilic bioactives: assembly, disassembly, and reassembly of lipid nanoparticles. Annu. Rev. Food Sci. Technol. 5 53-81.
    • (2014) Annu. Rev. Food Sci. Technol. , vol.5 , pp. 53-81
    • Yao, M.1    Xio, H.2    McClements, D.J.3
  • 268
    • 0036402133 scopus 로고    scopus 로고
    • Carotenoid bioavailability and bioconversion
    • K.J. Yeum and R.M. Russell (2002) Carotenoid bioavailability and bioconversion. Annu. Rev. Nutr. 22 483-504.
    • (2002) Annu. Rev. Nutr. , vol.22 , pp. 483-504
    • Yeum, K.J.1    Russell, R.M.2
  • 270
    • 84875780211 scopus 로고    scopus 로고
    • Self-nanoemulsifying drug delivery system of lutein: physicochemical properties and effect on bioavailability of warfarin
    • J. Yoo, R. Baskaran and B.K. Yoo (2013) Self-nanoemulsifying drug delivery system of lutein: physicochemical properties and effect on bioavailability of warfarin. Biomol. Ther. (Seoul) 21 173-179.
    • (2013) Biomol. Ther. (Seoul) , vol.21 , pp. 173-179
    • Yoo, J.1    Baskaran, R.2    Yoo, B.K.3
  • 271
    • 84925365060 scopus 로고    scopus 로고
    • Oral administration of nanoemulsion curcumin in mice suppresses inflammatory-induced NFκB signaling and macrophage migration
    • N.A. Young, M.S. Bruss, M. Gardner, W.L. Willis, X. Mo, G.R. Valiente, Y. Cao, Z. Liu, W.N. Jatjour and L.-C. Wu (2014) Oral administration of nanoemulsion curcumin in mice suppresses inflammatory-induced NFκB signaling and macrophage migration. PLoS One 9 e111559.
    • (2014) PLoS One , vol.9 , pp. e111559
    • Young, N.A.1    Bruss, M.S.2    Gardner, M.3    Willis, W.L.4    Mo, X.5    Valiente, G.R.6    Cao, Y.7    Liu, Z.8    Jatjour, W.N.9    Wu, L.-C.10
  • 272
    • 84861632327 scopus 로고    scopus 로고
    • Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions
    • H. Yu and Q. Huang (2012) Improving the oral bioavailability of curcumin using novel organogel-based nanoemulsions. J. Agric. Food Chem. 60 5373-5379.
    • (2012) J. Agric. Food Chem. , vol.60 , pp. 5373-5379
    • Yu, H.1    Huang, Q.2
  • 274
    • 79955703687 scopus 로고    scopus 로고
    • Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4
    • C.P. Yu, P.P. Wu, Y.C. Hou, S.P. Lin, S.Y. Tsai, C.T. Chen and P.D. Chao (2011) Quercetin and rutin reduced the bioavailability of cyclosporine from Neoral, an immunosuppressant, through activating P-glycoprotein and CYP 3A4. J. Agric. Food Chem. 59 4644-4648.
    • (2011) J. Agric. Food Chem. , vol.59 , pp. 4644-4648
    • Yu, C.P.1    Wu, P.P.2    Hou, Y.C.3    Lin, S.P.4    Tsai, S.Y.5    Chen, C.T.6    Chao, P.D.7
  • 275
    • 38049016308 scopus 로고    scopus 로고
    • Characterization and stability evaluation of β-carotene nanoemulsions prepared by high pressure homogenization under various emulsifying conditions
    • Y. Yuan, Y. Gao, J. Zhao and L. Mao (2008) Characterization and stability evaluation of β-carotene nanoemulsions prepared by high pressure homogenization under various emulsifying conditions. Food Res. Int. 41 61-68.
    • (2008) Food Res. Int. , vol.41 , pp. 61-68
    • Yuan, Y.1    Gao, Y.2    Zhao, J.3    Mao, L.4
  • 276
    • 36348970501 scopus 로고    scopus 로고
    • Optimization of conditions for the preparation of β-carotene nanoemulsions using response surface methodology
    • Y. Yuan, Y. Gao, L. Mao and J. Zhao (2008) Optimization of conditions for the preparation of β-carotene nanoemulsions using response surface methodology. Food Chem. 107 1300-1306.
    • (2008) Food Chem. , vol.107 , pp. 1300-1306
    • Yuan, Y.1    Gao, Y.2    Mao, L.3    Zhao, J.4
  • 277
    • 84865257742 scopus 로고    scopus 로고
    • Application of marine biomaterials for nutraceuticals and functional foods
    • C. Zhang, X. Li and S.-K. Kim (2012) Application of marine biomaterials for nutraceuticals and functional foods. Food Sci. Biotechnol. 21 625-631.
    • (2012) Food Sci. Biotechnol. , vol.21 , pp. 625-631
    • Zhang, C.1    Li, X.2    Kim, S.-K.3
  • 278
    • 54849419029 scopus 로고    scopus 로고
    • Nutraceuticals, nutritional therapy, phytonutrients, and phytotherapy for improvement of human health: a perspective on plant biotechnology application
    • J. Zhao (2007) Nutraceuticals, nutritional therapy, phytonutrients, and phytotherapy for improvement of human health: a perspective on plant biotechnology application. Recent Pat. Biotechnol. 1 75-97.
    • (2007) Recent Pat. Biotechnol. , vol.1 , pp. 75-97
    • Zhao, J.1
  • 279
    • 84875907608 scopus 로고    scopus 로고
    • Design and evaluation of a self-microemulsifying drug delivery system for apigenin
    • L. Zhao, L. Zhang, L. Meng, J. Wang and G. Zhai (2013) Design and evaluation of a self-microemulsifying drug delivery system for apigenin. Drug Dev. Ind. Pharm. 39 662-669.
    • (2013) Drug Dev. Ind. Pharm. , vol.39 , pp. 662-669
    • Zhao, L.1    Zhang, L.2    Meng, L.3    Wang, J.4    Zhai, G.5
  • 281
    • 84903625316 scopus 로고    scopus 로고
    • Novel lipid-free nanoformulation for improving oral bioavailability of coenzyme Q10
    • Article ID 793879
    • H. Zhou, G. Liu, J. Zhang, N. Sun, M. Duan, Z. TYan and Q. Xia (2014) Novel lipid-free nanoformulation for improving oral bioavailability of coenzyme Q10. Biomed. Res. Int. Article ID 793879
    • (2014) Biomed. Res. Int.
    • Zhou, H.1    Liu, G.2    Zhang, J.3    Sun, N.4    Duan, M.5    TYan, Z.6    Xia, Q.7
  • 282
    • 84905450778 scopus 로고    scopus 로고
    • Curcumin analogues with high activity for inhibiting human prostate cancer cell growth and androgen receptor activation
    • D.Y. Zhou, N. Ding, Z.Y. Du, X.X. Cui, H. Wang, X.C. Wei, A.H. Conney, K. Zhang and X. Zheng (2014) Curcumin analogues with high activity for inhibiting human prostate cancer cell growth and androgen receptor activation. Mol. Med. Rep. 10 1315-1322.
    • (2014) Mol. Med. Rep. , vol.10 , pp. 1315-1322
    • Zhou, D.Y.1    Ding, N.2    Du, Z.Y.3    Cui, X.X.4    Wang, H.5    Wei, X.C.6    Conney, A.H.7    Zhang, K.8    Zheng, X.9
  • 283
    • 84926442368 scopus 로고    scopus 로고
    • Involvement of the inhibition of intestinal glucuronidation in enhancing the oral bioavailability of resveratrol by labrasol containing nanoemulsions
    • J. Zhou, M. Zhou, F.F. Yang, C.Y. Liu, R.L. Pan, Q. Chang, X.M. Liu and Y.H. Liao (2015) Involvement of the inhibition of intestinal glucuronidation in enhancing the oral bioavailability of resveratrol by labrasol containing nanoemulsions. Mol. Pharm. 12 1084-1095.
    • (2015) Mol. Pharm. , vol.12 , pp. 1084-1095
    • Zhou, J.1    Zhou, M.2    Yang, F.F.3    Liu, C.Y.4    Pan, R.L.5    Chang, Q.6    Liu, X.M.7    Liao, Y.H.8
  • 284
    • 84873685615 scopus 로고    scopus 로고
    • Development of self-microemulsifying drug delivery system for oral bioavailability enhancement of berberine hydrochloride
    • J.X. Zhu, D. Tang, L. Feng, Z.G. Zheng, R.S. Wang, A.G. Wu, T.T. Duan, B. He and Q. Zhu (2013) Development of self-microemulsifying drug delivery system for oral bioavailability enhancement of berberine hydrochloride. Drug Dev. Ind. Pharm. 39 499-506.
    • (2013) Drug Dev. Ind. Pharm. , vol.39 , pp. 499-506
    • Zhu, J.X.1    Tang, D.2    Feng, L.3    Zheng, Z.G.4    Wang, R.S.5    Wu, A.G.6    Duan, T.T.7    He, B.8    Zhu, Q.9
  • 285
    • 84923334095 scopus 로고    scopus 로고
    • Utilizing food matrix effect to enhance nutraceutical bioavailability: increase of curcumin bioaccessibility using excipient emulsions
    • L. Zou, W. Liu, C. Liu, H. Xiao and D.J. McClements (2015) Utilizing food matrix effect to enhance nutraceutical bioavailability: increase of curcumin bioaccessibility using excipient emulsions. J. Agric. Food Chem. 63 2052-2062.
    • (2015) J. Agric. Food Chem. , vol.63 , pp. 2052-2062
    • Zou, L.1    Liu, W.2    Liu, C.3    Xiao, H.4    McClements, D.J.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.