Mucus as a barrier to lipophilic drugs

International Journal of Pharmaceutics

Volumn 453, Issue 1, 2013, Pages 56-64

  Sigurdsson, Hakon H ^a   Kirch, Julian ^b   Lehr, Claus Michael ^b,c  

^a UNIVERSITY OF ICELAND   (Iceland)

^b SAARLAND UNIVERSITY   (Germany)

^c SAARLAND UNIVERSITY   (Germany)

Author keywords

Diffusion; Drug absorption; Mucin; Mucopenetration; Permeability; Poorly soluble drug

Indexed keywords

ACICLOVIR; DESCICLOVIR; MOLECULAR LAYER; MUCIN; POLYMER; POLYSTYRENE; PROGESTERONE; TESTOSTERONE;

ATOMIC FORCE MICROSCOPY; CARCINOMA CELL; DIFFUSION; DISPERSION; DRUG ABSORPTION; DRUG BINDING; DRUG DELIVERY SYSTEM; DRUG SOLUBILITY; HUMAN; HYDROGEL; HYDROPHILICITY; HYDROPHOBICITY; INTESTINE CELL; LIPOPHILICITY; LUNG ALVEOLUS CELL; MEMBRANE PERMEABILITY; MOLECULAR WEIGHT; MUCOADHESION; MUCUS; MULTIGENE FAMILY; NONHUMAN; PARTICLE SIZE; PERMEABILITY BARRIER; PH; PRIORITY JOURNAL; PROTEIN ANALYSIS; PROTEIN CONFORMATION; PROTEIN INTERACTION; PROTEIN STRUCTURE; REVIEW; VISCOSITY;

EID: 84884125828     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2013.05.040     Document Type: Review

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