Quercetin-containing self-nanoemulsifying drug delivery system for improving oral bioavailability

Journal of Pharmaceutical Sciences

Volumn 103, Issue 3, 2014, Pages 840-852

  Tran, Thanh Huyen ^a   Guo, Yi ^b   Song, Donghui ^a   Bruno, Richard S ^b   Lu, Xiuling ^a  

^a UNIVERSITY OF CONNECTICUT   (United States)

^b OHIO STATE UNIVERSITY   (United States)

Author keywords

absorption; bioavailability; nanoparticle; oral drug delivery; pharmacokinetics; solubility

Indexed keywords

CASTOR OIL; CREMOPHOR; MACROGOL 400; POLYSORBATE 80; QUERCETIN; WATER; ANTIOXIDANT; EMULSIFYING AGENT; EXCIPIENT; MACROGOL DERIVATIVE; NANOMATERIAL; POLYSORBATE;

ANIMAL EXPERIMENT; ANIMAL MODEL; AREA UNDER THE CURVE; ARTICLE; CELL STRAIN CACO 2; COLON CARCINOMA; CONTROLLED STUDY; DRUG ABSORPTION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG DISTRIBUTION; DRUG PENETRATION; DRUG SOLUBILITY; DRUG STABILITY; FLUORESCENCE IMAGING; HUMAN; HUMAN CELL; MALE; MONOLAYER CULTURE; NANOEMULSION; NONHUMAN; RAT; SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM; ZETA POTENTIAL; ANIMAL; CACO 2 CELL LINE; CHEMISTRY; COMPARATIVE STUDY; DRUG FORMULATION; INTESTINE ABSORPTION; INTESTINE CELL; METABOLISM; ORAL DRUG ADMINISTRATION; SOLUBILITY; SPRAGUE DAWLEY RAT;

ADMINISTRATION, ORAL; ANIMALS; ANTIOXIDANTS; CACO-2 CELLS; CASTOR OIL; DRUG COMPOUNDING; DRUG DELIVERY SYSTEMS; DRUG STABILITY; EMULSIFYING AGENTS; ENTEROCYTES; EXCIPIENTS; HUMANS; INTESTINAL ABSORPTION; MALE; NANOSTRUCTURES; POLYETHYLENE GLYCOLS; POLYSORBATES; QUERCETIN; RATS; RATS, SPRAGUE-DAWLEY; SOLUBILITY;

EID: 84894442838     PISSN: 00223549     EISSN: 15206017     Source Type: Journal    
DOI: 10.1002/jps.23858     Document Type: Article

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