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Volumn 42, Issue 4, 2014, Pages 1191-1202

Macular pigment, visual function, and macular disease among subjects with alzheimer's disease: An exploratory study

Author keywords

Age related macular degeneration; Alzheimer's disease; cognitive function; contrast sensitivity; lutein; meso zeaxanthin; visual function; zeaxanthin

Indexed keywords

CAROTENOID; MESO ZEAXANTHIN; UNCLASSIFIED DRUG; VISUAL PIGMENT; XANTHOPHYLL; ZEAXANTHIN;

EID: 84907992094     PISSN: 13872877     EISSN: 18758908     Source Type: Journal    
DOI: 10.3233/JAD-140507     Document Type: Article
Times cited : (89)

References (61)
  • 3
    • 84858225391 scopus 로고    scopus 로고
    • 2012 Alzheimer's disease facts andfigures
    • - (2012) 2012 Alzheimer's disease facts andfigures. Alzheimers Dement 8, 131-168.
    • (2012) Alzheimers Dement , vol.8 , pp. 131-168
  • 4
    • 0030826642 scopus 로고    scopus 로고
    • Identification of lutein and zeaxanthin oxidation products in human and monkey retinas
    • Khachik F, Bernstein PS, Garland DL (1997) Identification of lutein and zeaxanthin oxidation products in human and monkey retinas. Invest Ophthalmol Vis Sci 38, 1802-1811.
    • (1997) Invest Ophthalmol Vis Sci , vol.38 , pp. 1802-1811
    • Khachik, F.1    Bernstein, P.S.2    Garland, D.L.3
  • 5
    • 84867784644 scopus 로고    scopus 로고
    • A possible role for lutein and zeaxanthin in cognitive function in the elderly
    • Johnson EJ (2012) A possible role for lutein and zeaxanthin in cognitive function in the elderly. Am J Clin Nutr 96, 1161S-1165S.
    • (2012) Am J Clin Nutr , vol.96 , pp. 1161S-1165S
    • Johnson, E.J.1
  • 6
    • 61849127473 scopus 로고
    • Separation, identification and quantification of carotenoids in fruits, vegetables and human plasma by high performance liquid chromatogra-phy
    • Khachik F, Beecher GR, Goli MB (1991) Separation, identification and quantification of carotenoids in fruits, vegetables and human plasma by high performance liquid chromatogra-phy. Pure Appl Chem 63, 71-80.
    • (1991) Pure Appl Chem , vol.63 , pp. 71-80
    • Khachik, F.1    Beecher, G.R.2    Goli, M.B.3
  • 7
    • 0034769744 scopus 로고    scopus 로고
    • Identification and quantitation of carotenoids and their metabolites in the tissues of the human eye
    • Bernstein PS, Khachik F, Carvalho LS, Muir GJ, Zhao DY, Katz NB (2001) Identification and quantitation of carotenoids and their metabolites in the tissues of the human eye. Exp Eye Res 72, 215-223.
    • (2001) Exp Eye Res , vol.72 , pp. 215-223
    • Bernstein, P.S.1    Khachik, F.2    Carvalho, L.S.3    Muir, G.J.4    Zhao, D.Y.5    Katz, N.B.6
  • 8
    • 34447115119 scopus 로고    scopus 로고
    • Measurement of macular pigment optical density using two different hete-rochromatic flicker photometers
    • Loane E, Stack J, Beatty S, Nolan JM (2007) Measurement of macular pigment optical density using two different hete-rochromatic flicker photometers. Curr Eye Res 32, 555-564.
    • (2007) Curr Eye Res , vol.32 , pp. 555-564
    • Loane, E.1    Stack, J.2    Beatty, S.3    Nolan, J.M.4
  • 14
    • 40549113353 scopus 로고    scopus 로고
    • Nutritional biomarkers in Alzheimer's disease: The association between carotenoids, n-3 fatty acids, and dementia severity
    • Wang W, Shinto L, Connor WE, Quinn JF (2008) Nutritional biomarkers in Alzheimer's disease: The association between carotenoids, n-3 fatty acids, and dementia severity. J Alzheimers Dis 13, 31-38.
    • (2008) J Alzheimers Dis , vol.13 , pp. 31-38
    • Wang, W.1    Shinto, L.2    Connor, W.E.3    Quinn, J.F.4
  • 15
    • 50449090701 scopus 로고    scopus 로고
    • Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women
    • Johnson EJ, McDonald K, Caldarella SM, Chung HY, Troen AM, Snodderly DM (2008) Cognitive findings of an exploratory trial of docosahexaenoic acid and lutein supplementation in older women. Nutr Neurosci 11, 75-83.
    • (2008) Nutr Neurosci , vol.11 , pp. 75-83
    • Johnson, E.J.1    McDonald, K.2    Caldarella, S.M.3    Chung, H.Y.4    Troen, A.M.5    Snodderly, D.M.6
  • 16
    • 76749143570 scopus 로고    scopus 로고
    • The relation between serum xanthophylls, fatty acids, macular pigment and cognitive function in the Health ABC Study
    • Renzi LM, Iannaccone A, Johnson E, Kritchevsky S (2008) The relation between serum xanthophylls, fatty acids, macular pigment and cognitive function in the Health ABC Study. FASEB J 22, 877.5.
    • (2008) FASEB J , vol.22 , pp. 877-5
    • Renzi, L.M.1    Iannaccone, A.2    Johnson, E.3    Kritchevsky, S.4
  • 17
    • 84881549710 scopus 로고    scopus 로고
    • Low macular pigment optical density is associated with lower cognitive performance in a large population-based sample of older adults
    • Feeney J, Finucane C, Savva GM, Cronin H, Beatty S, Nolan J, Kenny RA (2013) Low macular pigment optical density is associated with lower cognitive performance in a large population-based sample of older adults. Neurobiol Aging 34, 2449-2456.
    • (2013) Neurobiol Aging , vol.34 , pp. 2449-2456
    • Feeney, J.1    Finucane, C.2    Savva, G.M.3    Cronin, H.4    Beatty, S.5    Nolan, J.6    Kenny, R.A.7
  • 18
    • 79958098579 scopus 로고    scopus 로고
    • Parallel findings in age-related macu-lar degeneration and Alzheimer's disease
    • Ohno-Matsui K (2011) Parallel findings in age-related macu-lar degeneration and Alzheimer's disease. Prog Retin Eye Res 30, 217-238.
    • (2011) Prog Retin Eye Res , vol.30 , pp. 217-238
    • Ohno-Matsui, K.1
  • 20
    • 24944518543 scopus 로고    scopus 로고
    • CFF thresholds: Relation to macular pigment optical density
    • Hammond BR Jr, Wooten BR (2005) CFF thresholds: Relation to macular pigment optical density. Ophthalmic Physiol Opt 25, 315-319.
    • (2005) Ophthalmic Physiol Opt , vol.25 , pp. 315-319
    • Hammond, B.R.1    Wooten, B.R.2
  • 21
    • 0028092805 scopus 로고
    • Cambridge Neuropsychological Test Automated Battery (CANTAB): A factor analytic study of a large sample of normal elderly volunteers
    • Robbins TW, James M, Owen AM, Sahakian BJ, McInnes L, Rabbitt P (1994) Cambridge Neuropsychological Test Automated Battery (CANTAB): A factor analytic study of a large sample of normal elderly volunteers. Dementia 5, 266-281.
    • (1994) Dementia , vol.5 , pp. 266-281
    • Robbins, T.W.1    James, M.2    Owen, A.M.3    Sahakian, B.J.4    McInnes, L.5    Rabbitt, P.6
  • 22
    • 0023695325 scopus 로고
    • The effects of scopo-lamine on working memory in healthy young volunteers
    • Rusted JM, Warburton DM (1988) The effects of scopo-lamine on working memory in healthy young volunteers. Psychopharmacology (Berl) 96, 145-152.
    • (1988) Psychopharmacology (Berl) , vol.96 , pp. 145-152
    • Rusted, J.M.1    Warburton, D.M.2
  • 23
    • 0023904094 scopus 로고
    • A comparative study of visu-ospatial memory and learning in Alzheimer-type dementia and Parkinson's disease
    • Sahakian BJ, Morris RG, Evenden JL, Heald A, Levy R, Philpot M, Robbins TW (1988) A comparative study of visu-ospatial memory and learning in Alzheimer-type dementia and Parkinson's disease. Brain 111 (Pt 3), 695-718.
    • (1988) Brain , vol.111 , pp. 695-718
    • Sahakian, B.J.1    Morris, R.G.2    Evenden, J.L.3    Heald, A.4    Levy, R.5    Philpot, M.6    Robbins, T.W.7
  • 27
    • 80052610495 scopus 로고    scopus 로고
    • Psychophysical impact and optical and morphological characteristics of symptomatic non-advanced cataract
    • Charalampidou S, Nolan J, Loughman J, Stack J, Higgins G, Cassidy L, Beatty S (2011) Psychophysical impact and optical and morphological characteristics of symptomatic non-advanced cataract. Eye (Lond) 25, 1147-1154.
    • (2011) Eye (Lond) , vol.25 , pp. 1147-1154
    • Charalampidou, S.1    Nolan, J.2    Loughman, J.3    Stack, J.4    Higgins, G.5    Cassidy, L.6    Beatty, S.7
  • 28
    • 0028934221 scopus 로고
    • An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group
    • Bird AC, Bressler NM, Bressler SB, Chisholm IH, Coscas G, Davis DM, de Jong PT, Klaver CC, Klein BE, Klein R, et al. (1995) An international classification and grading system for age-related maculopathy and age-related macular degeneration. The International ARM Epidemiological Study Group. Surv Ophthalmol 39, 367-374.
    • (1995) Surv Ophthalmol , vol.39 , pp. 367-374
    • Bird, A.C.1    Bressler, N.M.2    Bressler, S.B.3    Chisholm, I.H.4    Coscas, G.5    Davis, D.M.6    De Jong, P.T.7    Klaver, C.C.8    Klein, B.E.9    Klein, R.10
  • 29
    • 4444376700 scopus 로고    scopus 로고
    • Autofluorescence method to measure macular pigment optical densities fluorometry and autoflu-orescence imaging
    • Delori FC (2004) Autofluorescence method to measure macular pigment optical densities fluorometry and autoflu-orescence imaging. Arch Biochem Biophys 430, 156-162.
    • (2004) Arch Biochem Biophys , vol.430 , pp. 156-162
    • Delori, F.C.1
  • 30
    • 84884952184 scopus 로고    scopus 로고
    • Concordance of macular pigment measurements obtained using customized heterochromatic flicker photometry, dual-wavelength autofluorescence, and single-wavelength reflectance
    • Dennison JL, Stack J, Beatty S, Nolan JM (2013) Concordance of macular pigment measurements obtained using customized heterochromatic flicker photometry, dual-wavelength autofluorescence, and single-wavelength reflectance. Exp Eye Res 116C, 190-198.
    • (2013) Exp Eye Res , vol.116 C , pp. 190-198
    • Dennison, J.L.1    Stack, J.2    Beatty, S.3    Nolan, J.M.4
  • 31
    • 84879190984 scopus 로고    scopus 로고
    • Serum response to supplemental macular carotenoids in subjects with and without age-related macular degeneration
    • Meagher KA, Thurnham DI, Beatty S, Howard AN, Connolly E, Cummins W, Nolan JM (2012) Serum response to supplemental macular carotenoids in subjects with and without age-related macular degeneration. Br J Nutr 110, 289-300.
    • (2012) Br J Nutr , vol.110 , pp. 289-300
    • Meagher, K.A.1    Thurnham, D.I.2    Beatty, S.3    Howard, A.N.4    Connolly, E.5    Cummins, W.6    Nolan, J.M.7
  • 35
    • 0026775958 scopus 로고
    • Free radical theory of aging
    • Harman D (1992) Free radical theory of aging. Mutat Res 275, 257-266.
    • (1992) Mutat Res , vol.275 , pp. 257-266
    • Harman, D.1
  • 36
    • 0033795036 scopus 로고    scopus 로고
    • The role of oxidative stress in the pathogenesis of age-related macular degeneration
    • Beatty S, Koh HH, Henson D, Boulton M (2000) The role of oxidative stress in the pathogenesis of age-related macular degeneration. Surv Ophthalmol 45, 115-134.
    • (2000) Surv Ophthalmol , vol.45 , pp. 115-134
    • Beatty, S.1    Koh, H.H.2    Henson, D.3    Boulton, M.4
  • 38
    • 0036741098 scopus 로고    scopus 로고
    • A role for local inflammation in the formation of drusen in the aging eye
    • Anderson DH, Mullins RF, Hageman GS, Johnson LV (2002) A role for local inflammation in the formation of drusen in the aging eye. Am J Ophthalmol 134, 411-431.
    • (2002) Am J Ophthalmol , vol.134 , pp. 411-431
    • Anderson, D.H.1    Mullins, R.F.2    Hageman, G.S.3    Johnson, L.V.4
  • 39
    • 4444226059 scopus 로고    scopus 로고
    • Inflammatory processes and Alzheimer's disease
    • Walsh S, Aisen PS (2004) Inflammatory processes and Alzheimer's disease. Expert Rev Neurother 4, 793-798.
    • (2004) Expert Rev Neurother , vol.4 , pp. 793-798
    • Walsh, S.1    Aisen, P.S.2
  • 40
    • 84872238424 scopus 로고    scopus 로고
    • Preventing Alzheimer's disease by targeting vascular risk factors: Hope and gap
    • Qiu C (2012) Preventing Alzheimer's disease by targeting vascular risk factors: Hope and gap. J Alzheimers Dis 32, 721-731.
    • (2012) J Alzheimers Dis , vol.32 , pp. 721-731
    • Qiu, C.1
  • 41
    • 33751205883 scopus 로고    scopus 로고
    • Risk factors for age-related maculopathy are associated with a relative lack of macular pigment
    • Nolan JM, Stack J, O'DO, Loane E, Beatty S (2007) Risk factors for age-related maculopathy are associated with a relative lack of macular pigment. Exp Eye Res 84, 61-74.
    • (2007) Exp Eye Res , vol.84 , pp. 61-74
    • Nolan, J.M.1    Stack, J.2    O'Do Loane, E.3    Beatty, S.4
  • 42
    • 0037442177 scopus 로고    scopus 로고
    • Alzheimer's disease and angiogenesis
    • Vagnucci AH Jr, Li WW (2003) Alzheimer's disease and angiogenesis. Lancet 361, 605-608.
    • (2003) Lancet , vol.361 , pp. 605-608
    • Vagnucci, A.H.1    Li, W.W.2
  • 46
    • 33645884103 scopus 로고    scopus 로고
    • Cognitive impairment in the Age-Related Eye Disease Study: AREDS report no. 16
    • Clemons TE, Rankin MW, McBee WL (2006) Cognitive impairment in the Age-Related Eye Disease Study: AREDS report no. 16. Arch Ophthalmol 124, 537-543.
    • (2006) Arch Ophthalmol , vol.124 , pp. 537-543
    • Clemons, T.E.1    Rankin, M.W.2    McBee, W.L.3
  • 47
    • 84877734641 scopus 로고    scopus 로고
    • Lutein + zeaxanthin and omega-3 fatty acids for age-related mac-ular degeneration: The Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial
    • Chew E, The AREDS2 Study Group (2013) Lutein + zeaxanthin and omega-3 fatty acids for age-related mac-ular degeneration: The Age-Related Eye Disease Study 2 (AREDS2) randomized clinical trial. JAMA 309, 2005-2015.
    • (2013) JAMA , vol.309 , pp. 2005-2015
    • Chew, E.1
  • 48
    • 84875142938 scopus 로고    scopus 로고
    • Secondary outcomes in a clinical trial of carotenoids with coantioxidants versus placebo in early age-related macular degeneration
    • Beatty S, Chakravarthy U, Nolan JM, Muldrew KA, Wood-side JV, Denny F, Stevenson MR (2013) Secondary outcomes in a clinical trial of carotenoids with coantioxidants versus placebo in early age-related macular degeneration. Ophthalmology 120, 600-606.
    • (2013) Ophthalmology , vol.120 , pp. 600-606
    • Beatty, S.1    Chakravarthy, U.2    Nolan, J.M.3    Muldrew, K.A.4    Wood-Side, J.V.5    Denny, F.6    Stevenson, M.R.7
  • 49
    • 84872201091 scopus 로고    scopus 로고
    • The impact of macular pigment augmentation on visual performance using different carotenoid formulations
    • Loughman J, Nolan JM, Howard AN, Connolly E, Meagher K, Beatty S (2012) The impact of macular pigment augmentation on visual performance using different carotenoid formulations. Invest Ophthalmol Vis Sci 53, 7871-7880.
    • (2012) Invest Ophthalmol Vis Sci , vol.53 , pp. 7871-7880
    • Loughman, J.1    Nolan, J.M.2    Howard, A.N.3    Connolly, E.4    Meagher, K.5    Beatty, S.6
  • 50
    • 84864295641 scopus 로고    scopus 로고
    • Macular carotenoid supplementation in subjects with atypical spatial profiles of macular pigment
    • Nolan JM, Akkali MC, Loughman J, Howard AN, Beatty S (2012) Macular carotenoid supplementation in subjects with atypical spatial profiles of macular pigment. Exp Eye Res 101, 9-15.
    • (2012) Exp Eye Res , vol.101 , pp. 9-15
    • Nolan, J.M.1    Akkali, M.C.2    Loughman, J.3    Howard, A.N.4    Beatty, S.5
  • 51
    • 84894240647 scopus 로고    scopus 로고
    • Evidence for including lutein and zeaxan-thin in oral supplements for age-related macular degeneration
    • Musch DC (2014) Evidence for including lutein and zeaxan-thin in oral supplements for age-related macular degeneration. JAMA Ophthalmol 132, 139-141.
    • (2014) JAMA Ophthalmol , vol.132 , pp. 139-141
    • Musch, D.C.1
  • 52
    • 84899840300 scopus 로고    scopus 로고
    • Serum lycopene, lutein and zeaxan-thin, and the risk of Alzheimer's disease mortality in older adults
    • Min JY, Min KB (2013) Serum lycopene, lutein and zeaxan-thin, and the risk of Alzheimer's disease mortality in older adults. Dement Geriatr Cogn Disord 37, 246-256.
    • (2013) Dement Geriatr Cogn Disord , vol.37 , pp. 246-256
    • Min, J.Y.1    Min, K.B.2
  • 54
    • 0035377610 scopus 로고    scopus 로고
    • Macular pigment density measured by autofluo-rescence spectrometry: Comparison with reflectometry and heterochromatic flicker photometry
    • Delori FC, Goger DG, Hammond BR, Snodderly DM, Burns SA (2001) Macular pigment density measured by autofluo-rescence spectrometry: Comparison with reflectometry and heterochromatic flicker photometry. J Opt Soc Am A Opt Image Sci Vis 18, 1212-1230.
    • (2001) J Opt Soc Am A Opt Image Sci Vis , vol.18 , pp. 1212-1230
    • Delori, F.C.1    Goger, D.G.2    Hammond, B.R.3    Snodderly, D.M.4    Burns, S.A.5
  • 55
    • 0017162574 scopus 로고
    • Beta-carotene content of certain organs from two patients receiving high doses of beta-carotene
    • Mathews-Roth MM, Abraham AA, Gabuzda TG (1976) Beta-carotene content of certain organs from two patients receiving high doses of beta-carotene. Clin Chem 22, 922-924.
    • (1976) Clin Chem , vol.22 , pp. 922-924
    • Mathews-Roth, M.M.1    Abraham, A.A.2    Gabuzda, T.G.3
  • 57
    • 0036176536 scopus 로고    scopus 로고
    • Impact of visual function on computer task accuracy and reaction time in a cohort of patients with age-related macular degeneration
    • Scott IU, Feuer WJ, Jacko JA (2002) Impact of visual function on computer task accuracy and reaction time in a cohort of patients with age-related macular degeneration. Am J Oph-thalmol 133, 350-357.
    • (2002) Am J Oph-thalmol , vol.133 , pp. 350-357
    • Scott, I.U.1    Feuer, W.J.2    Jacko, J.A.3
  • 58
    • 84862832885 scopus 로고    scopus 로고
    • Macular pigment and visual performance in glare: Benefits for photostress recovery, disability glare, and visual discomfort
    • Stringham JM, Garcia PV, Smith PA, McLin LN, Foutch BK (2011) Macular pigment and visual performance in glare: Benefits for photostress recovery, disability glare, and visual discomfort. Invest Ophthalmol Vis Sci 52, 7406-7415.
    • (2011) Invest Ophthalmol Vis Sci , vol.52 , pp. 7406-7415
    • Stringham, J.M.1    Garcia, P.V.2    Smith, P.A.3    McLin, L.N.4    Foutch, B.K.5
  • 59
    • 41349087050 scopus 로고    scopus 로고
    • A randomised controlled trial investigating the effect of lutein and antioxidant dietary supplementation on visual function in healthy eyes
    • Bartlett HE, Eperjesi F (2008) A randomised controlled trial investigating the effect of lutein and antioxidant dietary supplementation on visual function in healthy eyes. Clin Nutr 27, 218-227.
    • (2008) Clin Nutr , vol.27 , pp. 218-227
    • Bartlett, H.E.1    Eperjesi, F.2
  • 60
    • 84856256624 scopus 로고    scopus 로고
    • Effect of 1-year lutein supplementation on macular pigment optical density and visual function
    • Sasamoto Y, Gomi F, Sawa M, Tsujikawa M, Nishida K (2011) Effect of 1-year lutein supplementation on macular pigment optical density and visual function. Graefes Arch Clin Exp Ophthalmol 249, 1847-1854.
    • (2011) Graefes Arch Clin Exp Ophthalmol , vol.249 , pp. 1847-1854
    • Sasamoto, Y.1    Gomi, F.2    Sawa, M.3    Tsujikawa, M.4    Nishida, K.5
  • 61
    • 84858319307 scopus 로고    scopus 로고
    • A review of the evidence germane to the putative protective role of the macular carotenoids for age-related macular degeneration
    • Sabour-Pickett S, Nolan JM, Loughman J, Beatty S (2011) A review of the evidence germane to the putative protective role of the macular carotenoids for age-related macular degeneration. Mol Nutr Food Res 56, 270-286.
    • (2011) Mol Nutr Food Res , vol.56 , pp. 270-286
    • Sabour-Pickett, S.1    Nolan, J.M.2    Loughman, J.3    Beatty, S.4


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