Enhanced bioavailability and retinal accumulation of lutein from self-emulsifying phospholipid suspension (SEPS)

International Journal of Pharmaceutics

Volumn 412, Issue 1-2, 2011, Pages 99-105

  Shanmugam, Srinivasan ^a   Park, Jae Hyun ^a   Kim, Kyeong Soo ^a   Piao, Zong Zhu ^a   Yong, Chul Soon ^b   Choi, Han Gon ^c   Woo, Jong Soo ^a  

^a Hanmi Pharmaceutical Co Ltd   (South Korea)

^b Yeungnam University   (South Korea)

^c Hanyang University   (South Korea)

Author keywords

Lipid based oral drug delivery; Lutein; Pharmacokinetics bioavailability; Retinal accumulation; Self emulsifying phospholipid suspension

Indexed keywords

COSURFACTANT; EMULSIFYING AGENT; HUMECTANT; PHOSPHOLIPID DERIVATIVE; PLACEBO; POLYSORBATE 80; PROPYLENE GLYCOL CAPRYLATE; SELF EMULSIFYING PHOSPHOLIPID SUSPENSION; SURFACTANT; UNCLASSIFIED DRUG; XANTHOPHYLL;

ANIMAL EXPERIMENT; ANIMAL TISSUE; AREA UNDER THE CURVE; ARTICLE; CONTROLLED STUDY; DOG; DRUG ACCUMULATION; DRUG BIOAVAILABILITY; DRUG BLOOD LEVEL; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG STABILITY; DRUG STRUCTURE; EMULSION; MALE; MAXIMUM PLASMA CONCENTRATION; NONHUMAN; PRIORITY JOURNAL; RAT; RETINA; TIME TO MAXIMUM PLASMA CONCENTRATION;

ANIMALS; CAPSULES; DIETARY SUPPLEMENTS; DIFFUSION; DOGS; EMULSIFYING AGENTS; EMULSIONS; INTESTINAL ABSORPTION; KINETICS; LUTEIN; MALE; PHOSPHOLIPIDS; PHYSICOCHEMICAL PHENOMENA; RANDOM ALLOCATION; RATS; RATS, SPRAGUE-DAWLEY; RETINA; SOLUBILITY; SUSPENSIONS; TISSUE DISTRIBUTION;

EID: 79957521117     PISSN: 03785173     EISSN: 18733476     Source Type: Journal    
DOI: 10.1016/j.ijpharm.2011.04.015     Document Type: Article

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