-
1
-
-
0016906546
-
The flavonoids. A class of semi-essential food components: Their role in human nutrition
-
Kühnau J. The flavonoids. A class of semi-essential food components: their role in human nutrition. World Rev Nutr Diet 1976; 24: 177-191.
-
(1976)
World Rev Nutr Diet
, vol.24
, pp. 177-191
-
-
Kühnau, J.1
-
2
-
-
0018416167
-
Factors associated with cardiac mortality in developed countries with particular reference to the consumption of wine
-
St Leger AS et al. Factors associated with cardiac mortality in developed countries with particular reference to the consumption of wine. Lancet 1979; 1: 1017-1020.
-
(1979)
Lancet
, vol.1
, pp. 1017-1020
-
-
St Leger, A.S.1
-
4
-
-
0028644238
-
Free radical scavenging and antioxidant activity of plant flavonoids
-
Kandaswami C, Middleton E Jr. Free radical scavenging and antioxidant activity of plant flavonoids. Adv Exp Med Biol 1994; 366: 351-376.
-
(1994)
Adv Exp Med Biol
, vol.366
, pp. 351-376
-
-
Kandaswami, C.1
Middleton Jr., E.2
-
5
-
-
0037441423
-
Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2
-
Martin S et al. Delphinidin inhibits endothelial cell proliferation and cell cycle progression through a transient activation of ERK-1/-2. Biochem Pharmacol 2003; 65: 669-675.
-
(2003)
Biochem Pharmacol
, vol.65
, pp. 669-675
-
-
Martin, S.1
-
6
-
-
0042168910
-
Delphinidin, an active compound of red wine, inhibits endothelial cell apoptosis via nitric oxide pathway and regulation of calcium homeostasis
-
Martin S et al. Delphinidin, an active compound of red wine, inhibits endothelial cell apoptosis via nitric oxide pathway and regulation of calcium homeostasis. Br J Pharmacol 2003; 139: 1095-1102.
-
(2003)
Br J Pharmacol
, vol.139
, pp. 1095-1102
-
-
Martin, S.1
-
7
-
-
0032819772
-
Dietary flavonoids: Intake, health effects and bioavailability
-
Hollman PCH, Katan MB. Dietary flavonoids: intake, health effects and bioavailability. Food Chem Toxicol 1999; 37: 937-942.
-
(1999)
Food Chem Toxicol
, vol.37
, pp. 937-942
-
-
Hollman, P.C.H.1
Katan, M.B.2
-
8
-
-
0023257262
-
Drug transport in intestine liver and kidney
-
Schwenk M. Drug transport in intestine liver and kidney. Arch Toxicol 1987; 60: 37-42.
-
(1987)
Arch Toxicol
, vol.60
, pp. 37-42
-
-
Schwenk, M.1
-
9
-
-
39149115065
-
Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption
-
Custodio JM et al. Predicting drug disposition, absorption/elimination/transporter interplay and the role of food on drug absorption. Adv Drug Deliv Rev 2008; 60: 717-733.
-
(2008)
Adv Drug Deliv Rev
, vol.60
, pp. 717-733
-
-
Custodio, J.M.1
-
10
-
-
0032524982
-
Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells
-
Walgren RA et al. Transport of quercetin and its glucosides across human intestinal epithelial Caco-2 cells. Biochem Pharmacol 1998; 55: 1721-1727.
-
(1998)
Biochem Pharmacol
, vol.55
, pp. 1721-1727
-
-
Walgren, R.A.1
-
11
-
-
0034054933
-
Bioavailabilities of quercetin-3-glucoside and quercetin-4′-glucoside do not differ in humans
-
Olthof MR et al. Bioavailabilities of quercetin-3-glucoside and quercetin-4′-glucoside do not differ in humans. J Nutr 2000; 130: 1200-1203.
-
(2000)
J Nutr
, vol.130
, pp. 1200-1203
-
-
Olthof, M.R.1
-
12
-
-
0028793218
-
Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers
-
Hollmann PCH et al. Absorption of dietary quercetin glycosides and quercetin in healthy ileostomy volunteers. Am J Clin Nutr 1995; 62: 1276-1282.
-
(1995)
Am J Clin Nutr
, vol.62
, pp. 1276-1282
-
-
Hollmann, P.C.H.1
-
13
-
-
34547135694
-
Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake
-
Kottra G, Daniel H. Flavonoid glycosides are not transported by the human Na+/glucose transporter when expressed in Xenopus laevis oocytes, but effectively inhibit electrogenic glucose uptake. J Pharmacol Exp Ther 2007; 322: 829-835.
-
(2007)
J Pharmacol Exp Ther
, vol.322
, pp. 829-835
-
-
Kottra, G.1
Daniel, H.2
-
14
-
-
0142150026
-
The β-D-glucoside and sodium dependent glucose transporter 1 (SGLT1)-inhibitor phloridzin is transported by both SGLT1 and multidrug resistance associated proteins 1/2
-
Walle T, Walle UK. The β-D-glucoside and sodium dependent glucose transporter 1 (SGLT1)-inhibitor phloridzin is transported by both SGLT1 and multidrug resistance associated proteins 1/2. Drug Metab Dispos 2003; 31: 1288-1291.
-
(2003)
Drug Metab Dispos
, vol.31
, pp. 1288-1291
-
-
Walle, T.1
Walle, U.K.2
-
15
-
-
0033846534
-
Cellular uptake of dietary flavonoid quercetin 4′ beta glucoside by sodium dependent glucose transporter SGLT1
-
Walgren RA et al. Cellular uptake of dietary flavonoid quercetin 4′ beta glucoside by sodium dependent glucose transporter SGLT1. J Pharmacol Exp Ther 2000; 294: 837-843.
-
(2000)
J Pharmacol Exp Ther
, vol.294
, pp. 837-843
-
-
Walgren, R.A.1
-
16
-
-
3142549141
-
Quercetin glucosides inhibit glucose uptake into brush-border membrane vesicles of porcine jejunum
-
Cermak R et al. Quercetin glucosides inhibit glucose uptake into brush-border membrane vesicles of porcine jejunum. Br J Nutr 2004; 91: 849-855.
-
(2004)
Br J Nutr
, vol.91
, pp. 849-855
-
-
Cermak, R.1
-
17
-
-
18244376403
-
Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters
-
DiPietro A et al. Modulation by flavonoids of cell multidrug resistance mediated by P-glycoprotein and related ABC transporters. Cell Mol Life Sci 2002; 59: 307-322.
-
(2002)
Cell Mol Life Sci
, vol.59
, pp. 307-322
-
-
DiPietro, A.1
-
18
-
-
0032544087
-
Flavonoids: A class of modulators with bifunctional interactions at vicinal ATP- and steroid binding sites on mouse P-glycoprotein
-
Conseil G et al. Flavonoids: a class of modulators with bifunctional interactions at vicinal ATP- and steroid binding sites on mouse P-glycoprotein. Proc Natl Acad Sci USA 1998; 95: 9831-9836.
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 9831-9836
-
-
Conseil, G.1
-
19
-
-
0031790854
-
Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in Caco-2 cells
-
Takanaga H et al. Inhibition of vinblastine efflux mediated by P-glycoprotein by grapefruit juice components in Caco-2 cells. Biol Pharm Bull 1998; 21: 1062-1066.
-
(1998)
Biol Pharm Bull
, vol.21
, pp. 1062-1066
-
-
Takanaga, H.1
-
20
-
-
0031830305
-
Grapefruit juice-drug interactions
-
Bailey DG et al. Grapefruit juice-drug interactions. Br J Clin Pharmacol 1998; 46: 101-110.
-
(1998)
Br J Clin Pharmacol
, vol.46
, pp. 101-110
-
-
Bailey, D.G.1
-
21
-
-
75749134169
-
Interaction between the simvastatin, a HMG CoA reductase inhibitor, and the grapefruit juice: In vitro characterization and in vivo relevance
-
Pandalai SG, ed. Trivandrum, India: Research Signpost
-
Ubeaud G, Le Goff-Klein N. Interaction between the simvastatin, a HMG CoA reductase inhibitor, and the grapefruit juice: In vitro characterization and in vivo relevance. In: Recent Research Developments in Life Science, Pandalai SG, ed. Trivandrum, India: Research Signpost, 2005; 3: 337-352.
-
(2005)
Recent Research Developments in Life Science
, vol.3
, pp. 337-352
-
-
Ubeaud, G.1
Le Goff-Klein, N.2
-
22
-
-
0036825714
-
Comparison of in vitro hepatic models for the prediction of metabolic interaction between simvastatin and naringenin
-
Le Goff N et al. Comparison of in vitro hepatic models for the prediction of metabolic interaction between simvastatin and naringenin. Eur J Drug Metab Pharmacokinet 2002; 27: 233-241.
-
(2002)
Eur J Drug Metab Pharmacokinet
, vol.27
, pp. 233-241
-
-
Le Goff, N.1
-
23
-
-
0031000057
-
Initial pharmacokinetics and bioavailability of PSC 833, a P-glycoprotein antagonist
-
Lush RM et al. Initial pharmacokinetics and bioavailability of PSC 833, a P-glycoprotein antagonist. J Clin Pharmacol 1997; 37: 123-128.
-
(1997)
J Clin Pharmacol
, vol.37
, pp. 123-128
-
-
Lush, R.M.1
-
24
-
-
4644269603
-
Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy
-
Summers MA. Use of verapamil as a potential P-glycoprotein inhibitor in a patient with refractory epilepsy. Ann Pharmacother 2004; 38: 1631-1634.
-
(2004)
Ann Pharmacother
, vol.38
, pp. 1631-1634
-
-
Summers, M.A.1
-
25
-
-
30344432397
-
Multidrug resistance-associated protein 2(MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites
-
Mallants R et al. Multidrug resistance-associated protein 2(MRP2) affects hepatobiliary elimination but not the intestinal disposition of tenofovir disoproxil fumarate and its metabolites. Xenobiotica 2005; 35: 1055-1066.
-
(2005)
Xenobiotica
, vol.35
, pp. 1055-1066
-
-
Mallants, R.1
-
26
-
-
22144455747
-
Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4), that are present in human red cell membranes
-
Wu C et al. Interactions of mefloquine with ABC proteins, MRP1 (ABCC1) and MRP4 (ABCC4), that are present in human red cell membranes. Biochem Pharmacol 2005; 70: 500-510.
-
(2005)
Biochem Pharmacol
, vol.70
, pp. 500-510
-
-
Wu, C.1
-
27
-
-
0242469240
-
Organic anion-transporting polypeptide (OATP) transporter family and drug disposition
-
Kim RB. Organic anion-transporting polypeptide (OATP) transporter family and drug disposition. Eur J Clin Invest 2003; 33: 1-5.
-
(2003)
Eur J Clin Invest
, vol.33
, pp. 1-5
-
-
Kim, R.B.1
-
28
-
-
34250339664
-
Establishing acceptance criteria for cell-mediated-immunity assays using frozen peripheral blood mononuclear cells stored under optimal and suboptimal conditions
-
Smith JG et al. Establishing acceptance criteria for cell-mediated-immunity assays using frozen peripheral blood mononuclear cells stored under optimal and suboptimal conditions. Clin Vacc Immunol 2007: 527-537.
-
(2007)
Clin Vacc Immunol
, pp. 527-537
-
-
Smith, J.G.1
-
29
-
-
0025804183
-
Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells
-
Artursson P, Karlsson J. Correlation between oral drug absorption in humans and apparent drug permeability coefficients in human intestinal epithelial (Caco-2) cells. Biochem Biophys Res Commun 1991; 175: 880-885.
-
(1991)
Biochem Biophys Res Commun
, vol.175
, pp. 880-885
-
-
Artursson, P.1
Karlsson, J.2
-
30
-
-
4344594700
-
Transport characteristics of fexofenadine in the Caco-2 cell model
-
Petri N et al. Transport characteristics of fexofenadine in the Caco-2 cell model. Pharm Res 2004; 21: 1398-1404.
-
(2004)
Pharm Res
, vol.21
, pp. 1398-1404
-
-
Petri, N.1
-
31
-
-
0037122748
-
Graphical model for estimating oral bioavailability of drug in humans and others species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates
-
Mandagere K et al. Graphical model for estimating oral bioavailability of drug in humans and others species from their Caco-2 permeability and in vitro liver enzyme metabolic stability rates. J Med Chem 2002; 45: 304-311.
-
(2002)
J Med Chem
, vol.45
, pp. 304-311
-
-
Mandagere, K.1
-
32
-
-
0025311288
-
Epithelial transport of drugs in cell culture. I: A model for studying the passive diffusion of drugs over intestinal absorptive (Caco2) cells
-
Artursson P. Epithelial transport of drugs in cell culture. I: a model for studying the passive diffusion of drugs over intestinal absorptive (Caco2) cells. J Pharm Sci 1990; 79: 476-482.
-
(1990)
J Pharm Sci
, vol.79
, pp. 476-482
-
-
Artursson, P.1
-
33
-
-
0034333414
-
Phospholipids as multidrug resistance modulators of the transport of epirubicin in human intestinal epithelial Caco-2 cell layers and everted gut sacs of rats
-
Lo YL. Phospholipids as multidrug resistance modulators of the transport of epirubicin in human intestinal epithelial Caco-2 cell layers and everted gut sacs of rats. Biochem Pharmacol 2000; 60: 1381-1390.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1381-1390
-
-
Lo, Y.L.1
-
34
-
-
1642457252
-
Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human
-
Nozawa T et al. Functional characterization of pH-sensitive organic anion transporting polypeptide OATP-B in human. J Pharmacol Exp Ther 2004; 308: 438-445.
-
(2004)
J Pharmacol Exp Ther
, vol.308
, pp. 438-445
-
-
Nozawa, T.1
-
35
-
-
0042905800
-
Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium
-
Troutman MD, Thakker DR. Novel experimental parameters to quantify the modulation of absorptive and secretory transport of compounds by P-glycoprotein in cell culture models of intestinal epithelium. Pharm Res 2003; 20: 1210-1224.
-
(2003)
Pharm Res
, vol.20
, pp. 1210-1224
-
-
Troutman, M.D.1
Thakker, D.R.2
-
36
-
-
0034575539
-
The uncoupling efficiency and affinity of flavonoids for vesicles
-
Van Dijk C et al. The uncoupling efficiency and affinity of flavonoids for vesicles. Biochem Pharmacol 2000; 60: 1593-1600.
-
(2000)
Biochem Pharmacol
, vol.60
, pp. 1593-1600
-
-
Van Dijk, C.1
-
37
-
-
19444382806
-
pH dependent passive and active transport of acidic drugs across Caco-2 cell monolayers
-
Neuhoff S et al. pH dependent passive and active transport of acidic drugs across Caco-2 cell monolayers. Pharm Sci 2005; 25: 211-220.
-
(2005)
Pharm Sci
, vol.25
, pp. 211-220
-
-
Neuhoff, S.1
-
38
-
-
33644633081
-
Plant polyphenols and multidrug resistance: Effects of dietary flavonoids on drug transporters in Caco2 and MDCK II-MDR1 cell transport models
-
Rodriguez-Proteau R et al. Plant polyphenols and multidrug resistance: effects of dietary flavonoids on drug transporters in Caco2 and MDCK II-MDR1 cell transport models. Xenobiotica 2006; 36: 41-58.
-
(2006)
Xenobiotica
, vol.36
, pp. 41-58
-
-
Rodriguez-Proteau, R.1
-
39
-
-
0037311322
-
Effect of flavonoids on MRP1-mediated transport in Panc-1 cells
-
Nguyen H et al. Effect of flavonoids on MRP1-mediated transport in Panc-1 cells. J Pharm Sci 2003; 92: 250-257.
-
(2003)
J Pharm Sci
, vol.92
, pp. 250-257
-
-
Nguyen, H.1
-
40
-
-
19444385262
-
Modulation of drug transport by selected flavonoids: Involvement of P-gp and OCT?
-
Ofer M et al. Modulation of drug transport by selected flavonoids: involvement of P-gp and OCT? Eur J Pharm Sci 2005; 25: 263-271.
-
(2005)
Eur J Pharm Sci
, vol.25
, pp. 263-271
-
-
Ofer, M.1
-
41
-
-
0027132062
-
Flavonol-stimulated efflux of 7,12-dimethylbenz(a) anthracene in multidrug-resistant breast cancer cells
-
Phang JM et al. Flavonol-stimulated efflux of 7,12-dimethylbenz(a) anthracene in multidrug-resistant breast cancer cells. Cancer Res 1993; 53: 5977-5981.
-
(1993)
Cancer Res
, vol.53
, pp. 5977-5981
-
-
Phang, J.M.1
-
42
-
-
0027981909
-
Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target
-
Scambia G et al. Quercetin potentiates the effect of adriamycin in a multidrug-resistant MCF-7 human breast-cancer cell line: P-glycoprotein as a possible target. Cancer Chemother Pharmacol 1994; 34: 459-464.
-
(1994)
Cancer Chemother Pharmacol
, vol.34
, pp. 459-464
-
-
Scambia, G.1
-
43
-
-
3142549141
-
Quercetin glucosides inhibit glucose uptake into brush-border membrane vesicles of porcine jejunum
-
Cermak R et al. Quercetin glucosides inhibit glucose uptake into brush-border membrane vesicles of porcine jejunum. Br J Nutr 2004; 91: 849-855.
-
(2004)
Br J Nutr
, vol.91
, pp. 849-855
-
-
Cermak, R.1
-
44
-
-
36549022609
-
Transport of quercetin di-sodium salt in the human intestinal epithelial Caco2 cell monolayer
-
Milane HA et al. Transport of quercetin di-sodium salt in the human intestinal epithelial Caco2 cell monolayer. Eur J Drug Metab Pharm 2007; 32: 139-147.
-
(2007)
Eur J Drug Metab Pharm
, vol.32
, pp. 139-147
-
-
Milane, H.A.1
-
45
-
-
0034600237
-
Effect of bioflavonoids on vincristine transport across blood-brain barrier
-
Mitsunaga Y et al. Effect of bioflavonoids on vincristine transport across blood-brain barrier. Eur J Pharmacol 2000; 395: 193-201.
-
(2000)
Eur J Pharmacol
, vol.395
, pp. 193-201
-
-
Mitsunaga, Y.1
-
46
-
-
1642360726
-
Herbal modulation of P glycoprotein
-
Zhou S et al. Herbal modulation of P glycoprotein. Drug Metab Rev 2004; 36: 57-104.
-
(2004)
Drug Metab Rev
, vol.36
, pp. 57-104
-
-
Zhou, S.1
-
47
-
-
0142241274
-
Cellular uptake and efflux of the tea flavonoid (-) epicatechin 3 gallate in the human intestinal cell line Caco-2
-
Vaidyanathan JB, Walle T. Cellular uptake and efflux of the tea flavonoid (-) epicatechin 3 gallate in the human intestinal cell line Caco-2. J Pharm Exp Ther 2003; 307: 745-752.
-
(2003)
J Pharm Exp Ther
, vol.307
, pp. 745-752
-
-
Vaidyanathan, J.B.1
Walle, T.2
-
48
-
-
33845422617
-
In vitro evaluation of quercetin cutaneous absorption from topical formulations and its functional stability by antioxidant activity
-
Casagrandre R et al. In vitro evaluation of quercetin cutaneous absorption from topical formulations and its functional stability by antioxidant activity. Int J Pharm 2007; 328: 183-190.
-
(2007)
Int J Pharm
, vol.328
, pp. 183-190
-
-
Casagrandre, R.1
-
49
-
-
0022505086
-
Inhibiting or potentiating effects of flavonoids on carbon tetrachloride-induced toxicity in isolated rat hepatocytes
-
Perrissoud D, Testa B. Inhibiting or potentiating effects of flavonoids on carbon tetrachloride-induced toxicity in isolated rat hepatocytes. Arzneimittelforschung 1986; 36: 1249-1253.
-
(1986)
Arzneimittelforschung
, vol.36
, pp. 1249-1253
-
-
Perrissoud, D.1
Testa, B.2
|