Self-nanoemulsifying drug delivery system (SNEDDS) of the poorly water-soluble grapefruit flavonoid Naringenin: Design, characterization, in vitro and in vivo evaluation

Drug Delivery

Volumn 22, Issue 4, 2015, Pages 552-561

  Khan, Abdul Wadood ^a   Kotta, Sabna ^a   Ansari, Shahid Husain ^a   Sharma, Rakesh Kumar ^b   Ali, Javed ^a  

^a HAMDARD UNIVERSITY   (India)

^b INSTITUTE OF NUCLEAR MEDICINE AND ALLIED SCIENCES   (India)

Author keywords

Bioavailability; oil phase; pharmacokinetics; pseudoternary phase diagram; solubility

Indexed keywords

CARBOXYMETHYLCELLULOSE; FLAVONOID; NARINGENIN; OIL; SURFACTANT; WATER; EMULSION; FLAVANONE DERIVATIVE; NANOPARTICLE;

ANIMAL EXPERIMENT; ARTICLE; DRUG BIOAVAILABILITY; DRUG DELIVERY SYSTEM; DRUG FORMULATION; DRUG RELEASE; DRUG SOLUBILITY; GRAPEFRUIT; HIGH PERFORMANCE LIQUID CHROMATOGRAPHY; IN VITRO STUDY; IN VIVO STUDY; MALE; MAXIMUM PLASMA CONCENTRATION; NANOEMULSION; NONHUMAN; PLASMA CONCENTRATION-TIME CURVE; PRIORITY JOURNAL; RAT; SELF NANOEMULSIFYING DRUG DELIVERY SYSTEM; ANIMAL; AREA UNDER THE CURVE; BIOAVAILABILITY; CHEMISTRY; COMPARATIVE STUDY; EMULSION; MEDICINAL CHEMISTRY; ORAL DRUG ADMINISTRATION; PARTICLE SIZE; PROCEDURES; SOLUBILITY; WISTAR RAT;

ADMINISTRATION, ORAL; ANIMALS; AREA UNDER CURVE; BIOLOGICAL AVAILABILITY; CHEMISTRY, PHARMACEUTICAL; CITRUS PARADISI; DRUG DELIVERY SYSTEMS; DRUG LIBERATION; EMULSIONS; FLAVANONES; MALE; NANOPARTICLES; OILS; PARTICLE SIZE; RATS; RATS, WISTAR; SOLUBILITY; SURFACE-ACTIVE AGENTS;

EID: 84933515226     PISSN: 10717544     EISSN: 15210464     Source Type: Journal    
DOI: 10.3109/10717544.2013.878003     Document Type: Article

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