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Volumn 52, Issue 4, 2013, Pages 1381-1391

Effects of formulation on the bioavailability of lutein and zeaxanthin: A randomized, double-blind, cross-over, comparative, single-dose study in healthy subjects

Author keywords

all E lutein; Bioavailability; Carotenoids; Lutein; Xanthophylls; Zeaxanthin

Indexed keywords

ALGINIC ACID; FLORAGLO; STARCH; UNCLASSIFIED DRUG; XANTHOPHYLL; ZEAXANTHIN;

EID: 84878580426     PISSN: 14366207     EISSN: 14366215     Source Type: Journal    
DOI: 10.1007/s00394-012-0447-9     Document Type: Article
Times cited : (27)

References (28)
  • 1
    • 0034769744 scopus 로고    scopus 로고
    • Identification and quantitation of carotenoids and their metabolites in the tissues of the human eye
    • 10.1006/exer.2000.0954 1:CAS:528:DC%2BD3MXht1aqs7s%3D
    • Bernstein PS, Khachik F, Carvalho LS, Muir GJ, Zhao DY, Katz NB (2001) Identification and quantitation of carotenoids and their metabolites in the tissues of the human eye. Exp Eye Res 72:215-223
    • (2001) Exp Eye Res , vol.72 , pp. 215-223
    • Bernstein, P.S.1    Khachik, F.2    Carvalho, L.S.3    Muir, G.J.4    Zhao, D.Y.5    Katz, N.B.6
  • 2
    • 0024563906 scopus 로고
    • Antioxidant action of carotenoids
    • 1:CAS:528:DyaL1MXhtlCjsbY%3D
    • Burton GW (1989) Antioxidant action of carotenoids. J Nutr 119:109-111
    • (1989) J Nutr , vol.119 , pp. 109-111
    • Burton, G.W.1
  • 3
    • 0042866149 scopus 로고    scopus 로고
    • Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye
    • 10.1146/annurev.nutr.23.011702.073307 1:CAS:528:DC%2BD3sXntFSjurY%3D
    • Krinsky NI, Landrum JT, Bone RA (2003) Biologic mechanisms of the protective role of lutein and zeaxanthin in the eye. Annu Rev Nutr 23:171-201
    • (2003) Annu Rev Nutr , vol.23 , pp. 171-201
    • Krinsky, N.I.1    Landrum, J.T.2    Bone, R.A.3
  • 4
    • 77956640542 scopus 로고    scopus 로고
    • Intake of lutein and zeaxanthin differ with age, sex, and ethnicity
    • 10.1016/j.jada.2010.06.009 1:CAS:528:DC%2BC3cXhtV2hs73M
    • Johnson EJ, Maras JE, Rasmussen HM, Tucker KL (2010) Intake of lutein and zeaxanthin differ with age, sex, and ethnicity. J Am Diet Assoc 110:1357-1362
    • (2010) J Am Diet Assoc , vol.110 , pp. 1357-1362
    • Johnson, E.J.1    Maras, J.E.2    Rasmussen, H.M.3    Tucker, K.L.4
  • 7
    • 0031790247 scopus 로고    scopus 로고
    • Analysis of zeaxanthin distribution within individual human retinas
    • 10.1016/S0076-6879(99)99043-2 1:CAS:528:DyaK1MXpsFKi
    • Landrum JT, Bone RA, Moore LL, Gomez CM (1999) Analysis of zeaxanthin distribution within individual human retinas. Methods Enzymol 299:457-467
    • (1999) Methods Enzymol , vol.299 , pp. 457-467
    • Landrum, J.T.1    Bone, R.A.2    Moore, L.L.3    Gomez, C.M.4
  • 8
    • 0023897142 scopus 로고
    • Analysis of the macular pigment by HPLC: Retinal distribution and age study
    • 1:CAS:528:DyaL1cXkslSqtbk%3D
    • Bone RA, Landrum JT, Fernandez L, Tarsis SL (1988) Analysis of the macular pigment by HPLC: retinal distribution and age study. Invest Ophthalmol Vis Sci 29:843-849
    • (1988) Invest Ophthalmol Vis Sci , vol.29 , pp. 843-849
    • Bone, R.A.1    Landrum, J.T.2    Fernandez, L.3    Tarsis, S.L.4
  • 9
    • 0027034024 scopus 로고
    • Carotenoids in the retina-a review of their possible role in preventing or limiting damage caused by light and oxygen
    • Emerit I, Chance B (eds) Basel. Switzerland: Birkhauser, EXS
    • Schalch W (1992) Carotenoids in the retina-a review of their possible role in preventing or limiting damage caused by light and oxygen. In: Emerit I, Chance B (eds) Free radicals and aging. Basel, vol. 62. Switzerland: Birkhauser, EXS, pp 280-298
    • (1992) Free Radicals and Aging , vol.62 , pp. 280-298
    • Schalch, W.1
  • 10
    • 33845625763 scopus 로고    scopus 로고
    • Nutritional antioxidants and age-related cataract and maculopathy
    • 10.1016/j.exer.2006.05.015 1:CAS:528:DC%2BD2sXht1Wmtg%3D%3D
    • Chiu CJ, Taylor A (2007) Nutritional antioxidants and age-related cataract and maculopathy. Exp Eye Res 84:229-245
    • (2007) Exp Eye Res , vol.84 , pp. 229-245
    • Chiu, C.J.1    Taylor, A.2
  • 11
    • 0029131114 scopus 로고
    • Intestinal absorption, serum clearance, and interactions between lutein and beta-carotene when administered to human adults in separate or combined oral doses
    • 1:CAS:528:DyaK2MXosF2mt7s%3D
    • Kostic D, White WS, Olson JA (1995) Intestinal absorption, serum clearance, and interactions between lutein and beta-carotene when administered to human adults in separate or combined oral doses. Am J Clin Nutr 62(3):604-610
    • (1995) Am J Clin Nutr , vol.62 , Issue.3 , pp. 604-610
    • Kostic, D.1    White, W.S.2    Olson, J.A.3
  • 12
    • 0036898153 scopus 로고    scopus 로고
    • Esterification does not impair lutein bioavailability in humans
    • 1:CAS:528:DC%2BD38Xps12hurs%3D
    • Bowen PE, Herbst-Espinosa SM, Hussain EA, Stacewicz-Sapuntzakis M (2002) Esterification does not impair lutein bioavailability in humans. J Nutr 132(12):3668-3673
    • (2002) J Nutr , vol.132 , Issue.12 , pp. 3668-3673
    • Bowen, P.E.1    Herbst-Espinosa, S.M.2    Hussain, E.A.3    Stacewicz-Sapuntzakis, M.4
  • 13
    • 80054062088 scopus 로고    scopus 로고
    • Serum lutein response is greater from free lutein than from esterified lutein during 4 weeks of supplementation in healthy adults
    • 1:CAS:528:DC%2BC3MXosFGrs7k%3D
    • Norkus EP, Norkus KL, Dharmarajan TS, Schierle J, Schalch W (2010) Serum lutein response is greater from free lutein than from esterified lutein during 4 weeks of supplementation in healthy adults. J Am Coll Nutr 29:575-585
    • (2010) J Am Coll Nutr , vol.29 , pp. 575-585
    • Norkus, E.P.1    Norkus, K.L.2    Dharmarajan, T.S.3    Schierle, J.4    Schalch, W.5
  • 14
    • 23444460256 scopus 로고    scopus 로고
    • Plasma kinetics of lutein, zeaxanthin, and 3-dehydro-lutein after multiple oral doses of a lutein supplement
    • Thürmann PA, Schalch W, Aebischer JC, Tenter U, Cohn W (2005) Plasma kinetics of lutein, zeaxanthin, and 3-dehydro-lutein after multiple oral doses of a lutein supplement. Am J Clin Nutr 82:88-97
    • (2005) Am J Clin Nutr , vol.82 , pp. 88-97
    • Thürmann, P.A.1    Schalch, W.2    Aebischer, J.C.3    Tenter, U.4    Cohn, W.5
  • 15
    • 33846893634 scopus 로고    scopus 로고
    • Xanthophyll accumulation in the human retina during supplementation with lutein and zeaxanthin-the LUXEA (LUtein Xanthophyll Eye Accumulation) study
    • 10.1016/j.abb.2006.09.032 1:CAS:528:DC%2BD2sXhs1Cns7s%3D
    • Schalch W, Cohn W, Barker FM, Kõpcke W, Mellerio J, Bird AC, Robson AG, Fitzke FF, van Kuijk FJ (2007) Xanthophyll accumulation in the human retina during supplementation with lutein and zeaxanthin-the LUXEA (LUtein Xanthophyll Eye Accumulation) study. Arch Biochem Biophys 458:128-135
    • (2007) Arch Biochem Biophys , vol.458 , pp. 128-135
    • Schalch, W.1    Cohn, W.2    Barker, F.M.3    Kõpcke, W.4    Mellerio, J.5    Bird, A.C.6    Robson, A.G.7    Fitzke, F.F.8    Van Kuijk, F.J.9
  • 16
    • 0019362251 scopus 로고
    • Introduction to sample size determination and power analysis for clinical trials
    • 10.1016/0197-2456(81)90001-5 1:STN:280:DyaL38%2FgtlentA%3D%3D
    • Lachin JM (1981) Introduction to sample size determination and power analysis for clinical trials. Controlled Clin Trials 2:93-113
    • (1981) Controlled Clin Trials , vol.2 , pp. 93-113
    • Lachin, J.M.1
  • 17
    • 23644436300 scopus 로고    scopus 로고
    • Plasma kinetics of zeaxanthin and 3'-dehydro-lutein after multiple oral doses of synthetic zeaxanthin
    • 1:CAS:528:DC%2BD2cXhslOht7k%3D
    • Hartmann D, Thürmann PA, Spitzer V, Schalch W, Manner B, Cohn W (2004) Plasma kinetics of zeaxanthin and 3'-dehydro-lutein after multiple oral doses of synthetic zeaxanthin. Am J Clin Nutr 79:410-417
    • (2004) Am J Clin Nutr , vol.79 , pp. 410-417
    • Hartmann, D.1    Thürmann, P.A.2    Spitzer, V.3    Schalch, W.4    Manner, B.5    Cohn, W.6
  • 19
    • 0034150156 scopus 로고    scopus 로고
    • Use of a 13C tracer to quantify the plasma appearance of a physiological dose of lutein in humans
    • 10.1007/s11745-000-0531-0 1:CAS:528:DC%2BD3cXisVequr8%3D
    • Yao L, Liang Y, Trahanovsky WS, Serfass RE, White WS (2000) Use of a 13C tracer to quantify the plasma appearance of a physiological dose of lutein in humans. Lipids 35:339-348
    • (2000) Lipids , vol.35 , pp. 339-348
    • Yao, L.1    Liang, Y.2    Trahanovsky, W.S.3    Serfass, R.E.4    White, W.S.5
  • 20
    • 0026725047 scopus 로고
    • Distribution of orally administered beta-carotene among lipoproteins in healthy men
    • 1:CAS:528:DyaK38XltFSmuro%3D
    • Johnson EJ, Russell RM (1992) Distribution of orally administered beta-carotene among lipoproteins in healthy men. Am J Clin Nutr 56:128-135
    • (1992) Am J Clin Nutr , vol.56 , pp. 128-135
    • Johnson, E.J.1    Russell, R.M.2
  • 21
    • 2542432254 scopus 로고    scopus 로고
    • Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration:The Veternans LAST study (Lutein Antooxidant Supplementation Trial)
    • 10.1016/S1529-1839(04)70049-4
    • Richer S, Stiles W, Statkute L, Pulido J, Frankowski J, Rudy D, Pei K, Tsipursky M, Nyland J (2004) Double-masked, placebo-controlled, randomized trial of lutein and antioxidant supplementation in the intervention of atrophic age-related macular degeneration:the Veternans LAST study (Lutein Antooxidant Supplementation Trial). Optometry 75:216-230
    • (2004) Optometry , vol.75 , pp. 216-230
    • Richer, S.1    Stiles, W.2    Statkute, L.3    Pulido, J.4    Frankowski, J.5    Rudy, D.6    Pei, K.7    Tsipursky, M.8    Nyland, J.9
  • 23
    • 38349081533 scopus 로고    scopus 로고
    • Dietary carotenoids, vitamins C and E, and risk of cataract in women: A prospective study
    • 10.1001/archopht.126.1.102
    • Christen WG, Liu S, Glynn RJ, Gaziano JM, Buring JE (2008) Dietary carotenoids, vitamins C and E, and risk of cataract in women: a prospective study. Arch Ophthalmol 126:102-109
    • (2008) Arch Ophthalmol , vol.126 , pp. 102-109
    • Christen, W.G.1    Liu, S.2    Glynn, R.J.3    Gaziano, J.M.4    Buring, J.E.5


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.