Beyond ATM: The protein kinase landscape of the DNA damage response

FEBS Letters

Volumn 585, Issue 11, 2011, Pages 1625-1639

  Bensimon, Ariel ^a   Aebersold, Ruedi ^a,b   Shiloh, Yosef ^c  

^a ETH ZURICH   (Switzerland)

^b UNIVERSITY OF ZURICH   (Switzerland)

^c TEL AVIV UNIVERSITY   (Israel)

Author keywords

DNA damage response; Genome stability; Protein kinase; Protein phosphorylation; Systems biology

Indexed keywords

ABELSON KINASE; ATM PROTEIN; ATR PROTEIN; AURORA A KINASE; AURORA B KINASE; CASEIN KINASE II; CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; CYCLIN DEPENDENT KINASE 1; CYCLIN DEPENDENT KINASE 2; CYCLIN DEPENDENT KINASE 4; CYCLIN DEPENDENT KINASE 5; CYCLIN DEPENDENT KINASE 6; DOUBLE STRANDED RNA; I KAPPA B KINASE; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MAMMALIAN TARGET OF RAPAMYCIN; MITOGEN ACTIVATED PROTEIN KINASE; MITOGEN ACTIVATED PROTEIN KINASE 3; MIXED LINEAGE KINASE 3; P21 ACTIVATED KINASE 2; PHOSPHATIDYLINOSITOL 3 KINASE; POLO LIKE KINASE 3; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN KINASE D; PROTEIN KINASE LYN; PROTEIN MDM2; STRESS ACTIVATED PROTEIN KINASE;

AUTOPHOSPHORYLATION; DNA DAMAGE; DOUBLE STRANDED DNA BREAK; DOWN REGULATION; ENZYME ACTIVITY; ENZYME DEGRADATION; GENOMIC INSTABILITY; HIGH THROUGHPUT SCREENING; HUMAN; MITOSIS; MOLECULAR INTERACTION; NONHUMAN; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN MODIFICATION; PROTEIN MOTIF; PROTEIN PHOSPHORYLATION; PROTEIN PROTEIN INTERACTION; REVIEW; SIGNAL TRANSDUCTION;

ANIMALS; CELL CYCLE PROTEINS; DNA DAMAGE; DNA-BINDING PROTEINS; HUMANS; PROTEIN KINASES; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

EID: 79957547966     PISSN: 00145793     EISSN: 18733468     Source Type: Journal    
DOI: 10.1016/j.febslet.2011.05.013     Document Type: Review

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