-
1
-
-
0027233603
-
Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme
-
Alessi, D. R., A. J. Street, P. Cohen, and P. T. Cohen. 1993. Inhibitor-2 functions like a chaperone to fold three expressed isoforms of mammalian protein phosphatase-1 into a conformation with the specificity and regulatory properties of the native enzyme. Eur. J. Biochem. 213:1055-1066.
-
(1993)
Eur. J. Biochem
, vol.213
, pp. 1055-1066
-
-
Alessi, D.R.1
Street, A.J.2
Cohen, P.3
Cohen, P.T.4
-
2
-
-
1042301303
-
Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation
-
Ali, A., J. Zhang, S. Bao, I. Liu, D. Otterness, N. M. Dean, R. T. Abraham, and X. F. Wang. 2004. Requirement of protein phosphatase 5 in DNA-damage-induced ATM activation. Genes Dev. 18:249-254.
-
(2004)
Genes Dev
, vol.18
, pp. 249-254
-
-
Ali, A.1
Zhang, J.2
Bao, S.3
Liu, I.4
Otterness, D.5
Dean, N.M.6
Abraham, R.T.7
Wang, X.F.8
-
3
-
-
0037081563
-
Protein phosphatase 1 - targeted in many directions
-
Cohen, P. T. 2002. Protein phosphatase 1 - targeted in many directions. J. Cell Sci. 115:241-256.
-
(2002)
J. Cell Sci
, vol.115
, pp. 241-256
-
-
Cohen, P.T.1
-
4
-
-
0025313882
-
Protein serine/threonine phosphatases; an expanding family
-
Cohen, P. T., N. D. Brewis, V. Hughes, and D. J. Mann. 1990. Protein serine/threonine phosphatases; an expanding family. FEBS Lett. 268:355-359.
-
(1990)
FEBS Lett
, vol.268
, pp. 355-359
-
-
Cohen, P.T.1
Brewis, N.D.2
Hughes, V.3
Mann, D.J.4
-
5
-
-
0037341143
-
Disruption of the striated muscle glycogen targeting subunit PPP1R3A of protein phosphatase 1 leads to increased weight gain, fat deposition, and development of insulin resistance
-
Delibegovic, M., C. G. Armstrong, L. Dobbie, P. W. Watt, A. J. Smith, and P. T. Cohen. 2003. Disruption of the striated muscle glycogen targeting subunit PPP1R3A of protein phosphatase 1 leads to increased weight gain, fat deposition, and development of insulin resistance. Diabetes 52:596-604.
-
(2003)
Diabetes
, vol.52
, pp. 596-604
-
-
Delibegovic, M.1
Armstrong, C.G.2
Dobbie, L.3
Watt, P.W.4
Smith, A.J.5
Cohen, P.T.6
-
6
-
-
1842614272
-
Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1
-
Den Elzen, N. R., and M. J. O'Connell. 2004. Recovery from DNA damage checkpoint arrest by PP1-mediated inhibition of Chk1. EMBO J. 23:908-918.
-
(2004)
EMBO J
, vol.23
, pp. 908-918
-
-
Den Elzen, N.R.1
O'Connell, M.J.2
-
7
-
-
0035848819
-
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
-
Falck, J., N. Mailand, R. G. Syljuasen, J. Bartek, and J. Likas. 2001. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 410:842-847.
-
(2001)
Nature
, vol.410
, pp. 842-847
-
-
Falck, J.1
Mailand, N.2
Syljuasen, R.G.3
Bartek, J.4
Likas, J.5
-
8
-
-
10044225999
-
Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A
-
Goodarzi, A. A., J. C. Jonnalagadda, P. Douglas, D. Young, R. Ye, G. B. Moorhead, S. P. Lees-Miller, and K. K. Khanna. 2004. Autophosphorylation of ataxia-telangiectasia mutated is regulated by protein phosphatase 2A. EMBO J. 23:4451-4461.
-
(2004)
EMBO J
, vol.23
, pp. 4451-4461
-
-
Goodarzi, A.A.1
Jonnalagadda, J.C.2
Douglas, P.3
Young, D.4
Ye, R.5
Moorhead, G.B.6
Lees-Miller, S.P.7
Khanna, K.K.8
-
9
-
-
0036829505
-
Ionizing radiation activates nuclear protein phosphatase-1 by ATM-dependent dephosphorylation
-
Guo, C. Y., D. L. Brautigan, and J. M. Larner. 2002. Ionizing radiation activates nuclear protein phosphatase-1 by ATM-dependent dephosphorylation. J. Biol. Chem. 277:41756-41761.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 41756-41761
-
-
Guo, C.Y.1
Brautigan, D.L.2
Larner, J.M.3
-
10
-
-
0034604354
-
Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes
-
Hsu, J. Y., Z. W. Sun, X. Li, M. Reuben, K. Tatchell, D. K. Bishop, J. M. Grushcow, C. J. Brame, J. A. Caldwell, D. F. Hunt, R. Lin, M. M. Smith, and C. D. Allis. 2000. Mitotic phosphorylation of histone H3 is governed by Ipl1/aurora kinase and Glc7/PP1 phosphatase in budding yeast and nematodes. Cell 102:279-291.
-
(2000)
Cell
, vol.102
, pp. 279-291
-
-
Hsu, J.Y.1
Sun, Z.W.2
Li, X.3
Reuben, M.4
Tatchell, K.5
Bishop, D.K.6
Grushcow, J.M.7
Brame, C.J.8
Caldwell, J.A.9
Hunt, D.F.10
Lin, R.11
Smith, M.M.12
Allis, C.D.13
-
11
-
-
0017130995
-
Separation and characterization of two phosphorylase phosphatase inhibitors from rabbit skeletal muscle
-
Huang, F. L., and W. H. Glinsmann. 1976. Separation and characterization of two phosphorylase phosphatase inhibitors from rabbit skeletal muscle. Eur. J. Biochem. 70:419-426.
-
(1976)
Eur. J. Biochem
, vol.70
, pp. 419-426
-
-
Huang, F.L.1
Glinsmann, W.H.2
-
12
-
-
0033621392
-
Substrate specificities and identification of putative substrates of ATM kinase family members
-
Kim, S.-T., D.-S. Lim, C. E. Canman, and M. B. Kastan. 1999. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274:37538-37543.
-
(1999)
J. Biol. Chem
, vol.274
, pp. 37538-37543
-
-
Kim, S.-T.1
Lim, D.-S.2
Canman, C.E.3
Kastan, M.B.4
-
13
-
-
0036500555
-
Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage
-
Kim, S. T., B. Xu, and M. B. Kastan. 2002. Involvement of the cohesin protein, Smc1, in Atm-dependent and independent responses to DNA damage. Genes Dev. 16:560-570.
-
(2002)
Genes Dev
, vol.16
, pp. 560-570
-
-
Kim, S.T.1
Xu, B.2
Kastan, M.B.3
-
14
-
-
2642528031
-
DNA damage-induced activation of ATM and ATM-dependent signaling pathways
-
Kurz, E. U., and S. P. Lees-Miller. 2004. DNA damage-induced activation of ATM and ATM-dependent signaling pathways. DNA Repair (Amsterdam) 3:889-900.
-
(2004)
DNA Repair (Amsterdam)
, vol.3
, pp. 889-900
-
-
Kurz, E.U.1
Lees-Miller, S.P.2
-
15
-
-
0038168237
-
Phosphorylation of phosphatase inhibitor-2 at centrosomes during mitosis
-
Leach, C., S. Shenolikar, and D. L. Brautigan. 2003. Phosphorylation of phosphatase inhibitor-2 at centrosomes during mitosis. J. Biol. Chem. 278:26015-26020.
-
(2003)
J. Biol. Chem
, vol.278
, pp. 26015-26020
-
-
Leach, C.1
Shenolikar, S.2
Brautigan, D.L.3
-
16
-
-
0030592715
-
Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation
-
MacKintosh, C., A. J. Garton, A. McDonnell, D. Barford, P. T. Cohen, N. K. Tonks, and P. Cohen. 1996. Further evidence that inhibitor-2 acts like a chaperone to fold PP1 into its native conformation. FEBS Lett. 397:235-238.
-
(1996)
FEBS Lett
, vol.397
, pp. 235-238
-
-
MacKintosh, C.1
Garton, A.J.2
McDonnell, A.3
Barford, D.4
Cohen, P.T.5
Tonks, N.K.6
Cohen, P.7
-
17
-
-
34249947699
-
ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage
-
Matsuoka, S., B. A. Ballif, A. Smogorzewska, E. R. McDonald III, K. E. Hurov, J. Luo, C. E. Bakalarski, Z. Zhao, N. Solimini, Y. Lerenthal, Y. Shiloh, S. P. Gygi, and S. J. Elledge. 2007. ATM and ATR substrate analysis reveals extensive protein networks responsive to DNA damage. Science 316:1160-1166.
-
(2007)
Science
, vol.316
, pp. 1160-1166
-
-
Matsuoka, S.1
Ballif, B.A.2
Smogorzewska, A.3
McDonald III, E.R.4
Hurov, K.E.5
Luo, J.6
Bakalarski, C.E.7
Zhao, Z.8
Solimini, N.9
Lerenthal, Y.10
Shiloh, Y.11
Gygi, S.P.12
Elledge, S.J.13
-
18
-
-
26444569913
-
Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage
-
Monaco, L., U. Kolthur-Seetharam, R. Loury, J. M. Murcia, M. G. de, and P. Sassone-Corsi. 2005. Inhibition of Aurora-B kinase activity by poly(ADP-ribosyl)ation in response to DNA damage. Proc. Natl. Acad. Sci. USA 102:14244-14248.
-
(2005)
Proc. Natl. Acad. Sci. USA
, vol.102
, pp. 14244-14248
-
-
Monaco, L.1
Kolthur-Seetharam, U.2
Loury, R.3
Murcia, J.M.4
de, M.G.5
Sassone-Corsi, P.6
-
20
-
-
0036314290
-
Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G(L) of liver
-
Munro, S., D. J. Cuthbertson, J. Cunningham, M. Sales, and P. T. Cohen. 2002. Human skeletal muscle expresses a glycogen-targeting subunit of PP1 that is identical to the insulin-sensitive glycogen-targeting subunit G(L) of liver. Diabetes 51:591-598.
-
(2002)
Diabetes
, vol.51
, pp. 591-598
-
-
Munro, S.1
Cuthbertson, D.J.2
Cunningham, J.3
Sales, M.4
Cohen, P.T.5
-
21
-
-
0032159462
-
Physiologic importance of protein phosphatase inhibitors
-
Oliver, C. J., and S. Shenolikar. 1998. Physiologic importance of protein phosphatase inhibitors. Front. Biosci. 3:D961-D972.
-
(1998)
Front. Biosci
, vol.3
-
-
Oliver, C.J.1
Shenolikar, S.2
-
22
-
-
0034725592
-
Utilization of oriented peptide libraries to identify substrate motifs selected by ATM
-
O'Neill, T., A. J. Dwyer, Y. Ziv, D. W. Chan, S. P. Lees-Miller, R. H. Abraham, J. H. Lai, D. Hill, Y. Shiloh, L. C. Cantley, and G. A. Rathbun. 2000. Utilization of oriented peptide libraries to identify substrate motifs selected by ATM. J. Biol. Chem. 275:22719-22727.
-
(2000)
J. Biol. Chem
, vol.275
, pp. 22719-22727
-
-
O'Neill, T.1
Dwyer, A.J.2
Ziv, Y.3
Chan, D.W.4
Lees-Miller, S.P.5
Abraham, R.H.6
Lai, J.H.7
Hill, D.8
Shiloh, Y.9
Cantley, L.C.10
Rathbun, G.A.11
-
23
-
-
0028143054
-
Domains of phosphatase inhibitor-2 involved in the control of the ATP-Mg-dependent protein phosphatase
-
Park, I. K., and A. A. Paoli-Roach. 1994. Domains of phosphatase inhibitor-2 involved in the control of the ATP-Mg-dependent protein phosphatase. J. Biol. Chem. 269:28919-28928.
-
(1994)
J. Biol. Chem
, vol.269
, pp. 28919-28928
-
-
Park, I.K.1
Paoli-Roach, A.A.2
-
24
-
-
0029953320
-
Evidence that the endogenous histone H1 phosphatase in HeLa mitotic chromosomes is protein phosphatase 1, not protein phosphatase 2A
-
Paulson, J. R., J. S. Patzlaff, and A. J. Vallis. 1996. Evidence that the endogenous histone H1 phosphatase in HeLa mitotic chromosomes is protein phosphatase 1, not protein phosphatase 2A. J. Cell Sci. 109:1437-1447.
-
(1996)
J. Cell Sci
, vol.109
, pp. 1437-1447
-
-
Paulson, J.R.1
Patzlaff, J.S.2
Vallis, A.J.3
-
25
-
-
0034798285
-
ATM: Genome stability, neuronal development, and cancer cross paths. Adv. Cancer Res
-
Shiloh, Y., and M. B. Kastan. 2001. ATM: genome stability, neuronal development, and cancer cross paths. Adv. Cancer Res. 83:209-254.
-
(2001)
, vol.83
, pp. 209-254
-
-
Shiloh, Y.1
Kastan, M.B.2
-
26
-
-
33745823159
-
The ATM-mediated DNA-damage response: Taking shape
-
Shiloh, Y. 2006. The ATM-mediated DNA-damage response: taking shape. Trends Biochem. Sci. 31:402-410.
-
(2006)
Trends Biochem. Sci
, vol.31
, pp. 402-410
-
-
Shiloh, Y.1
-
27
-
-
0037123768
-
Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways
-
Taniguchi, T., I. Garcia-Higuera, B. Xu, P. R. Andreassen, R. C. Gregory, S. T. Kim, W. S. Lane, M. B. Kastan, and A. D. D'Andrea. 2002. Convergence of the fanconi anemia and ataxia telangiectasia signaling pathways. Cell 109:459-472.
-
(2002)
Cell
, vol.109
, pp. 459-472
-
-
Taniguchi, T.1
Garcia-Higuera, I.2
Xu, B.3
Andreassen, P.R.4
Gregory, R.C.5
Kim, S.T.6
Lane, W.S.7
Kastan, M.B.8
D'Andrea, A.D.9
-
28
-
-
0030047194
-
-
Vijayaraghavan, S., D. T. Stephens, K. Trautman, G. D. Smith, B. Khatra, E. F. da Cruz e Silva, and P. Greengard. 1996. Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity. Biol. Reprod. 54:709-718.
-
Vijayaraghavan, S., D. T. Stephens, K. Trautman, G. D. Smith, B. Khatra, E. F. da Cruz e Silva, and P. Greengard. 1996. Sperm motility development in the epididymis is associated with decreased glycogen synthase kinase-3 and protein phosphatase 1 activity. Biol. Reprod. 54:709-718.
-
-
-
-
29
-
-
0037147232
-
A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2
-
Wang, H., and D. L. Brautigan. 2002. A novel transmembrane Ser/Thr kinase complexes with protein phosphatase-1 and inhibitor-2. J. Biol. Chem. 277:49605-49612.
-
(2002)
J. Biol. Chem
, vol.277
, pp. 49605-49612
-
-
Wang, H.1
Brautigan, D.L.2
-
31
-
-
0036146085
-
Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation
-
Xu, B., S. T. Kim, D. S. Lim, and M. B. Kastan. 2002. Two molecularly distinct G(2)/M checkpoints are induced by ionizing irradiation. Mol. Cell. Biol. 22:1049-1059.
-
(2002)
Mol. Cell. Biol
, vol.22
, pp. 1049-1059
-
-
Xu, B.1
Kim, S.T.2
Lim, D.S.3
Kastan, M.B.4
-
32
-
-
0037102275
-
Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation
-
Xu, B., A. H. O'Donnell, S. T. Kim, and M. B. Kastan. 2002. Phosphorylation of serine 1387 in Brca1 is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation. Cancer Res. 62:4588-4591.
-
(2002)
Cancer Res
, vol.62
, pp. 4588-4591
-
-
Xu, B.1
O'Donnell, A.H.2
Kim, S.T.3
Kastan, M.B.4
-
33
-
-
0036500690
-
SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint
-
Yazdi, P. T., Y. Wang, S. Zhao, N. Patel, E. Y. Lee, and J. Qin. 2002. SMC1 is a downstream effector in the ATM/NBS1 branch of the human S-phase checkpoint. Genes Dev. 16:571-582.
-
(2002)
Genes Dev
, vol.16
, pp. 571-582
-
-
Yazdi, P.T.1
Wang, Y.2
Zhao, S.3
Patel, N.4
Lee, E.Y.5
Qin, J.6
-
34
-
-
27644435088
-
Protein phosphatase 5 is required for ATR-mediated checkpoint activation
-
Zhang, J., S. Bao, R. Furumai, K. S. Kucera, A. Ali, N. M. Dean, and X. F. Wang. 2005. Protein phosphatase 5 is required for ATR-mediated checkpoint activation. Mol. Cell. Biol. 25:9910-9919.
-
(2005)
Mol. Cell. Biol
, vol.25
, pp. 9910-9919
-
-
Zhang, J.1
Bao, S.2
Furumai, R.3
Kucera, K.S.4
Ali, A.5
Dean, N.M.6
Wang, X.F.7
|