Full activation of PKB/Akt in response to insulin or ionizing radiation is mediated through ATM

Journal of Biological Chemistry

Volumn 280, Issue 6, 2005, Pages 4029-4036

  Guinea Viniegra, Juan ^a   Martínez, Natalia ^b   Modirassari, Pegah ^a   Hernández Losa, Javier ^c   Parada Cobo, Carlos ^c   Sánchez Arévalo Lobo, Victor Javier ^d   Aceves Luquero, Clara Isabel ^a   Álvarez Vallina, Luis ^d   Ramón Y Cajal, Santiago ^c   Rojas, José María ^b   Sánchez Prieto, Ricardo ^a  

^a Universidad de Castilla La Mancha   (Spain)

^b INSTITUTO DE SALUD CARLOS III   (Spain)

^c HOSPITAL UNIVERSITARI VALL D HEBRON   (Spain)

^d HOSPITAL UNIVERSITARIO PUERTA DE HIERRO   (Spain)

Author keywords

[No Author keywords available]

Indexed keywords

BIOASSAY; BIOLOGICAL RADIATION EFFECTS; CHEMICAL ACTIVATION; CYTOLOGY; DNA; GAMMA RAYS; GENES; IONIZING RADIATION; MUTAGENESIS;

ATAXIA TELANGIECTASIA MUTATION (ATM); CELL CYCLE; PHOSPHORYLATION;

INSULIN;

ATM PROTEIN; INSULIN; PHOSPHATIDYLINOSITOL 3 KINASE; PHOSPHOTRANSFERASE INHIBITOR; PROTEIN KINASE B; SERINE; SMALL INTERFERING RNA; TRANSCRIPTION FACTOR; TRANSCRIPTION FACTOR OF THE FORKHEAD FAMILY; UNCLASSIFIED DRUG;

ANIMAL CELL; ANIMAL EXPERIMENT; ANIMAL MODEL; ARTICLE; ATAXIA TELANGIECTASIA; ATM GENE; CELL CYCLE; CELL FUNCTION; CELL STRAIN COS1; CONTROLLED STUDY; DNA DAMAGE; ENZYME ACTIVATION; ENZYME PHOSPHORYLATION; GENE; GENE MUTATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IN VIVO STUDY; INSULIN RESISTANCE; INSULIN RESPONSE; IONIZING RADIATION; KNOCKOUT MOUSE; MOUSE; NONHUMAN; PRIORITY JOURNAL; RADIOSENSITIVITY; SIGNAL TRANSDUCTION;

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMALS; CELL CYCLE PROTEINS; CELL LINE; CELLS, CULTURED; COS CELLS; DNA-BINDING PROTEINS; DOSE-RESPONSE RELATIONSHIP, RADIATION; FIBROBLASTS; GAMMA RAYS; HUMANS; IMMUNOPRECIPITATION; INSULIN; MICE; MICE, KNOCKOUT; MODELS, BIOLOGICAL; MUTATION; PHENOTYPE; PHOSPHORYLATION; PROTEIN BINDING; PROTEIN STRUCTURE, TERTIARY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-AKT; RADIATION, IONIZING; RNA, SMALL INTERFERING; SERINE; TIME FACTORS; TRANSFECTION; TRANSGENES; TUMOR SUPPRESSOR PROTEIN P53; TUMOR SUPPRESSOR PROTEINS;

EID: 20044390541     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M410344200     Document Type: Article

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