New Cdc2 Tyr 4 phosphorylation by dsRNA-activated protein kinase triggers Cdc2 polyubiquitination and G2 arrest under genotoxic stresses

EMBO Reports

Volumn 11, Issue 5, 2010, Pages 393-399

  Yoon, Cheol Hee ^a   Miah, Mohammad Alam ^a   Kim, Kwang Pyo ^b   Bae, Yong Soo ^a,c  

^a Sungkyunkwan University   (South Korea)

^b Konkuk University   (South Korea)

^c CreaGene Research Institute   (South Korea)

Author keywords

Cdc2; G2 M transition; PKR; Polyubiquitination; Tyr 4 phosphorylation

Indexed keywords

CELL CYCLE PROTEIN 20; DOUBLE STRANDED RNA; PROTEIN P53; TYROSINE;

AMINO TERMINAL SEQUENCE; ARTICLE; CELL CYCLE ARREST; CELL CYCLE G2 PHASE; CELL STRESS; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVITY; ENZYME SUBSTRATE; GENE OVEREXPRESSION; GENOTOXICITY; HUMAN; HUMAN CELL; MUTATION; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PHOSPHORYLATION; RECEPTOR DOWN REGULATION; UBIQUITINATION;

CDC2 PROTEIN KINASE; DNA DAMAGE; DOWN-REGULATION; EIF-2 KINASE; G2 PHASE; HCT116 CELLS; HUMANS; MUTATION; PHOSPHORYLATION; PHOSPHOTYROSINE; POLYUBIQUITIN; PROTEIN PROCESSING, POST-TRANSLATIONAL; UBIQUITINATION;

EID: 77951880589     PISSN: 1469221X     EISSN: 14693178     Source Type: Journal    
DOI: 10.1038/embor.2010.45     Document Type: Article

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