A genetic screen identifies the Triple T complex required for DNA damage signaling and ATM and ATR stability

Genes and Development

Volumn 24, Issue 17, 2010, Pages 1939-1950

  Hurov, Kristen E ^a   Cotta Ramusino, Cecilia ^a   Elledge, Stephen J ^a  

^a BRIGHAM AND WOMEN S HOSPITAL   (United States)

Author keywords

IR sensitivity; PIKK; TEL2; TTI1; TTI2; TTT complex

Indexed keywords

ATM PROTEIN; ATR PROTEIN; CELL PROTEIN; DEOXYRIBONUCLEOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; TEL TWO INTERACTING PROTEIN 1; TEL TWO INTERACTING PROTEIN 2; UNCLASSIFIED DRUG;

ARTICLE; CELL CYCLE G2 PHASE; CELL CYCLE M PHASE; CELL CYCLE S PHASE; CONTROLLED STUDY; DNA DAMAGE; GENETIC SCREENING; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN DEPLETION; PROTEIN FUNCTION; PROTEIN STABILITY; RNA INTERFERENCE; TELOMERE;

1-PHOSPHATIDYLINOSITOL 4-KINASE; CARRIER PROTEINS; CELL CYCLE; CELL CYCLE PROTEINS; CELL LINE; CELL LINE, TUMOR; DNA DAMAGE; DNA-BINDING PROTEINS; GENES, CDC; GENOME-WIDE ASSOCIATION STUDY; HUMANS; INFRARED RAYS; PROTEIN STABILITY; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-ETS; RNA INTERFERENCE; SIGNAL TRANSDUCTION; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA; MAMMALIA;

EID: 77956283656     PISSN: 08909369     EISSN: 15495477     Source Type: Journal    
DOI: 10.1101/gad.1934210     Document Type: Article

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