P38 MAPK and JNK antagonistically control senescence and cytoplasmic p16ink4a expression in doxorubicin-treated endothelial progenitor cells

PLoS ONE

Volumn 5, Issue 12, 2010, Pages

  Spallarossa, Paolo ^a   Altieri, Paola ^a   Barisione, Chiara ^a   Passalacqua, Mario ^a   Aloi, Concetta ^a   Fugazza, Giuseppina ^b   Frassoni, Francesco ^c   Podestá, Marina ^c   Canepa, Marco ^a   Ghigliotti, Giorgio ^a   Brunelli, Claudio ^a  

^a UNIVERSITY OF GENOA   (Italy)

^b UNIVERSITY OF GENOA   (Italy)

^c UNIVERSITY OF GENOA   (Italy)

Author keywords

[No Author keywords available]

Indexed keywords

BETA GALACTOSIDASE; CYCLIN DEPENDENT KINASE INHIBITOR 2A; DOXORUBICIN; MITOGEN ACTIVATED PROTEIN KINASE P38; STRESS ACTIVATED PROTEIN KINASE; TELOMERIC REPEAT BINDING FACTOR 2; MITOGEN ACTIVATED PROTEIN KINASE KINASE 4;

APOPTOSIS; ARTICLE; CARDIOTOXICITY; CELL CYCLE ARREST; CHROMOSOME ANALYSIS; CONTROLLED STUDY; CYTOSKELETON; DRUG ACTIVITY; ENDOTHELIAL PROGENITOR CELL; ENZYME ACTIVITY; HEART MUSCLE CELL; HUMAN; HUMAN CELL; IMMUNOCYTOCHEMISTRY; PHENOTYPE; PROTEIN ANALYSIS; PROTEIN EXPRESSION; PROTEIN LOCALIZATION; SENESCENCE; ANIMAL; CELL AGING; CULTURE MEDIUM; CYTOLOGY; CYTOPLASM; DRUG EFFECT; ENDOTHELIUM CELL; ENZYMOLOGY; FETUS BLOOD; METABOLISM; MONONUCLEAR CELL; MOUSE; SIGNAL TRANSDUCTION; STEM CELL;

ANIMALS; CELL AGING; CULTURE MEDIA, CONDITIONED; CYCLIN-DEPENDENT KINASE INHIBITOR P16; CYTOPLASM; DOXORUBICIN; ENDOTHELIAL CELLS; FETAL BLOOD; HUMANS; LEUKOCYTES, MONONUCLEAR; MAP KINASE KINASE 4; MAP KINASE SIGNALING SYSTEM; MICE; MYOCYTES, CARDIAC; P38 MITOGEN-ACTIVATED PROTEIN KINASES; STEM CELLS;

EID: 78650917095     PISSN: None     EISSN: 19326203     Source Type: Journal    
DOI: 10.1371/journal.pone.0015583     Document Type: Article

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