-
1
-
-
0035449355
-
Cell cycle checkpoint signaling through the ATM and ATR kinases
-
Abraham, R.T. 2001. Cell cycle checkpoint signaling through the ATM and ATR kinases. Genes & Dev. 15: 2177-2196.
-
(2001)
Genes & Dev.
, vol.15
, pp. 2177-2196
-
-
Abraham, R.T.1
-
2
-
-
0037472924
-
DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
-
Bakkenist, C.J. and Kastan, M.B. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421: 499-506.
-
(2003)
Nature
, vol.421
, pp. 499-506
-
-
Bakkenist, C.J.1
Kastan, M.B.2
-
3
-
-
0035927713
-
ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses
-
Bao, S., Tibbetts, R.S., Brumbaugh, K.M., Fang, Y., Richardson, D.A., Ali, A., Chen, S.M., Abraham, R.T., and Wang, X.F. 2001. ATR/ATM-mediated phosphorylation of human Rad17 is required for genotoxic stress responses. Nature 411: 969-974.
-
(2001)
Nature
, vol.411
, pp. 969-974
-
-
Bao, S.1
Tibbetts, R.S.2
Brumbaugh, K.M.3
Fang, Y.4
Richardson, D.A.5
Ali, A.6
Chen, S.M.7
Abraham, R.T.8
Wang, X.F.9
-
4
-
-
0035793943
-
Nuclear localization of protein phosphatase 5 is dependent on the carboxyterminal region
-
Borthwick, E.B., Zeke, T., Prescott, A.R., and Cohen, P.T. 2001. Nuclear localization of protein phosphatase 5 is dependent on the carboxyterminal region. FEBS Lett. 491: 279-284.
-
(2001)
FEBS Lett.
, vol.491
, pp. 279-284
-
-
Borthwick, E.B.1
Zeke, T.2
Prescott, A.R.3
Cohen, P.T.4
-
5
-
-
0031015069
-
Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain
-
Chen, M.X. and Cohen, P.T. 1997. Activation of protein phosphatase 5 by limited proteolysis or the binding of polyunsaturated fatty acids to the TPR domain. FEBS Lett. 400: 136-140.
-
(1997)
FEBS Lett.
, vol.400
, pp. 136-140
-
-
Chen, M.X.1
Cohen, P.T.2
-
6
-
-
0028133445
-
A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus
-
Chen, M.X., McPartlin, A.E., Brown, L., Chen, Y.H., Barker, H.M., and Cohen, P.T. 1994. A novel human protein serine/threonine phosphatase, which possesses four tetratricopeptide repeat motifs and localizes to the nucleus. EMBO J. 13: 4278-4290.
-
(1994)
EMBO J.
, vol.13
, pp. 4278-4290
-
-
Chen, M.X.1
McPartlin, A.E.2
Brown, L.3
Chen, Y.H.4
Barker, H.M.5
Cohen, P.T.6
-
7
-
-
0035234311
-
Protein phosphatase 5 in signal transduction
-
Chinkers, M. 2001. Protein phosphatase 5 in signal transduction. Trends Endocrinol. Metab. 12: 28-32.
-
(2001)
Trends Endocrinol. Metab.
, vol.12
, pp. 28-32
-
-
Chinkers, M.1
-
8
-
-
0032472330
-
Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints
-
Cliby, W.A., Roberts, C.J., Cimprich, K.A., Stringer, C.M., Lamb, J.R., Schreiber, S.L., and Friend, S.H. 1998. Overexpression of a kinase-inactive ATR protein causes sensitivity to DNA-damaging agents and defects in cell cycle checkpoints. EMBO J. 17: 159-169.
-
(1998)
EMBO J.
, vol.17
, pp. 159-169
-
-
Cliby, W.A.1
Roberts, C.J.2
Cimprich, K.A.3
Stringer, C.M.4
Lamb, J.R.5
Schreiber, S.L.6
Friend, S.H.7
-
10
-
-
0033527717
-
Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks
-
Cortez, D., Wang, Y., Qin, J., and Elledge, S.J. 1999. Requirement of ATM-dependent phosphorylation of brca1 in the DNA damage response to double-strand breaks. Science 286: 1162-1166.
-
(1999)
Science
, vol.286
, pp. 1162-1166
-
-
Cortez, D.1
Wang, Y.2
Qin, J.3
Elledge, S.J.4
-
11
-
-
0035374588
-
Protein phosphatases regulate DNA-dependent protein kinase activity
-
Douglas, P., Moorhead, G.B., Ye, R., and Lees-Miller, S.P. 2001. Protein phosphatases regulate DNA-dependent protein kinase activity. J. Biol. Chem. 276: 18992-18998.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 18992-18998
-
-
Douglas, P.1
Moorhead, G.B.2
Ye, R.3
Lees-Miller, S.P.4
-
12
-
-
0032478271
-
A simplified system for generating recombinant adenoviruses
-
He, T.C., Zhou, S., da Costa, L.T., Yu, J., Kinzler, K.W., and Vogelstein, B. 1998. A simplified system for generating recombinant adenoviruses. Proc. Natl. Acad. Sci. 95: 2509-2514.
-
(1998)
Proc. Natl. Acad. Sci.
, vol.95
, pp. 2509-2514
-
-
He, T.C.1
Zhou, S.2
Da Costa, L.T.3
Yu, J.4
Kinzler, K.W.5
Vogelstein, B.6
-
13
-
-
0034576494
-
The many substrates and functions of ATM
-
Kastan, M.B. and Lim, D.S. 2000. The many substrates and functions of ATM. Nat. Rev. Mol. Cell. Biol. 1: 179-186.
-
(2000)
Nat. Rev. Mol. Cell. Biol.
, vol.1
, pp. 179-186
-
-
Kastan, M.B.1
Lim, D.S.2
-
14
-
-
0038660596
-
ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation
-
Kozlov, S., Gueven, N., Keating, K., Ramsay, J., and Lavin, M.F. 2003. ATP activates ataxia-telangiectasia mutated (ATM) in vitro. Importance of autophosphorylation. J. Biol. Chem. 278: 9309-9317.
-
(2003)
J. Biol. Chem.
, vol.278
, pp. 9309-9317
-
-
Kozlov, S.1
Gueven, N.2
Keating, K.3
Ramsay, J.4
Lavin, M.F.5
-
15
-
-
0035914309
-
Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: Evidence for a heterotrimeric form of protein phosphatase 5
-
Lubert, E.J., Hong, Y., and Sarge, K.D. 2001. Interaction between protein phosphatase 5 and the A subunit of protein phosphatase 2A: Evidence for a heterotrimeric form of protein phosphatase 5. J. Biol. Chem. 276: 38582-38587.
-
(2001)
J. Biol. Chem.
, vol.276
, pp. 38582-38587
-
-
Lubert, E.J.1
Hong, Y.2
Sarge, K.D.3
-
16
-
-
0035503696
-
Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress
-
Morita, K., Saitoh, M., Tobiume, K., Matsuura, H., Enomoto, S., Nishitoh, H., and Ichijo, H. 2001. Negative feedback regulation of ASK1 by protein phosphatase 5 (PP5) in response to oxidative stress. EMBO J. 20: 6028-6036.
-
(2001)
EMBO J.
, vol.20
, pp. 6028-6036
-
-
Morita, K.1
Saitoh, M.2
Tobiume, K.3
Matsuura, H.4
Enomoto, S.5
Nishitoh, H.6
Ichijo, H.7
-
17
-
-
0025988705
-
Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates
-
Norbury, C., Blow, J., and Nurse, P. 1991. Regulatory phosphorylation of the p34cdc2 protein kinase in vertebrates. EMBO J. 10: 3321-3329.
-
(1991)
EMBO J.
, vol.10
, pp. 3321-3329
-
-
Norbury, C.1
Blow, J.2
Nurse, P.3
-
18
-
-
0031437422
-
The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex
-
Ollendorff, V. and Donoghue, D.J. 1997. The serine/threonine phosphatase PP5 interacts with CDC16 and CDC27, two tetratricopeptide repeat-containing subunits of the anaphase-promoting complex. J. Biol. Chem. 272: 32011-32018.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 32011-32018
-
-
Ollendorff, V.1
Donoghue, D.J.2
-
19
-
-
0037197702
-
Identification of potential physiological activators of protein phosphatase 5
-
Ramsey, A.J. and Chinkers, M. 2002. Identification of potential physiological activators of protein phosphatase 5. Biochemistry 41: 5625-5632.
-
(2002)
Biochemistry
, vol.41
, pp. 5625-5632
-
-
Ramsey, A.J.1
Chinkers, M.2
-
20
-
-
0029057336
-
A single ataxia telangiectasia gene with a product similar to PI-3 kinase
-
Savitsky, K., Bar-Shira, A., Gilad, S., Rotman, G., Ziv, Y., Vanagaite, L., Tagle, D.A., Smith, S., Uziel, T., Sfez, S., et al. 1995. A single ataxia telangiectasia gene with a product similar to PI-3 kinase. Science 268: 1749-1753.
-
(1995)
Science
, vol.268
, pp. 1749-1753
-
-
Savitsky, K.1
Bar-Shira, A.2
Gilad, S.3
Rotman, G.4
Ziv, Y.5
Vanagaite, L.6
Tagle, D.A.7
Smith, S.8
Uziel, T.9
Sfez, S.10
-
21
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh, Y. 2003. ATM and related protein kinases: Safeguarding genome integrity. Nat. Rev. Cancer 3: 155-168.
-
(2003)
Nat. Rev. Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
22
-
-
0030921056
-
Protein phosphatase 5 is a major component of glucocorticoid receptor · hsp90 complexes with properties of an FK506-binding immunophilin
-
Silverstein, A.M., Galigniana, M.D., Chen, M.S., Owens-Grillo, J.K., Chinkers, M., and Pratt, W.B. 1997. Protein phosphatase 5 is a major component of glucocorticoid receptor · hsp90 complexes with properties of an FK506-binding immunophilin. J. Biol. Chem. 272: 16224-16230.
-
(1997)
J. Biol. Chem.
, vol.272
, pp. 16224-16230
-
-
Silverstein, A.M.1
Galigniana, M.D.2
Chen, M.S.3
Owens-Grillo, J.K.4
Chinkers, M.5
Pratt, W.B.6
-
23
-
-
0033551778
-
The tetratricopeptide repeat domain and a C-terminal region control the activity of Ser/Thr protein phosphatase 5
-
Sinclair, C., Borchers, C., Parker, C., Tomer, K., Charbonneau, H., and Rossie, S. 1999. The tetratricopeptide repeat domain and a C-terminal region control the activity of Ser/Thr protein phosphatase 5. J. Biol. Chem. 274: 23666-23672.
-
(1999)
J. Biol. Chem.
, vol.274
, pp. 23666-23672
-
-
Sinclair, C.1
Borchers, C.2
Parker, C.3
Tomer, K.4
Charbonneau, H.5
Rossie, S.6
-
24
-
-
0033555260
-
A role for ATR in the DNA damage-induced phosphorylation of p53
-
Tibbetts, R.S., Brumbaugh, K.M., Williams, I.M., Sarkaria, I.N., Cliby, W.A., Shieh, S.Y., Taya, Y., Prives, C., and Abraham, R.T. 1999. A role for ATR in the DNA damage-induced phosphorylation of p53. Genes & Dev. 13: 152-157.
-
(1999)
Genes & Dev.
, vol.13
, pp. 152-157
-
-
Tibbetts, R.S.1
Brumbaugh, K.M.2
Williams, I.M.3
Sarkaria, I.N.4
Cliby, W.A.5
Shieh, S.Y.6
Taya, Y.7
Prives, C.8
Abraham, R.T.9
-
25
-
-
0142136826
-
Requirement of the MRN complex for ATM activation by DNA damage
-
Uziel, T., Lerenthal, Y., Moyal, L., Andegeko, Y., Mittelman, L., and Shiloh, Y. 2003. Requirement of the MRN complex for ATM activation by DNA damage. EMBO J. 22: 5612-5621.
-
(2003)
EMBO J.
, vol.22
, pp. 5612-5621
-
-
Uziel, T.1
Lerenthal, Y.2
Moyal, L.3
Andegeko, Y.4
Mittelman, L.5
Shiloh, Y.6
-
26
-
-
0037031156
-
13 interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity
-
13 interact with Ser/Thr protein phosphatase type 5 and stimulate its phosphatase activity. Curr. Biol. 12: 1353-1358.
-
(2002)
Curr. Biol.
, vol.12
, pp. 1353-1358
-
-
Yamaguchi, Y.1
Katoh, H.2
Mori, K.3
Negishi, M.4
-
27
-
-
0034707047
-
The DNA damage response: Putting checkpoints in perspective
-
Zhou, B.B. and Elledge, S.J. 2000. The DNA damage response: Putting checkpoints in perspective. Nature 408: 433-439.
-
(2000)
Nature
, vol.408
, pp. 433-439
-
-
Zhou, B.B.1
Elledge, S.J.2
-
28
-
-
0037080675
-
Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin
-
Zou, L., Cortez, D., and Elledge, S.J. 2002. Regulation of ATR substrate selection by Rad17-dependent loading of Rad9 complexes onto chromatin. Genes & Dev. 16: 198-208.
-
(2002)
Genes & Dev.
, vol.16
, pp. 198-208
-
-
Zou, L.1
Cortez, D.2
Elledge, S.J.3
|