A role for PI 3-kinase and PKB activity in the G2/M phase of the cell cycle

Current Biology

Volumn 12, Issue 11, 2002, Pages 919-924

  Shtivelman, Emma ^a   Sussman, Joshua ^a   Stokoe, David ^a  

^a UNIVERSITY OF CALIFORNIA   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

1-PHOSPHATIDYLINOSITOL 3-KINASE; ANIMAL; CATTLE; G2 PHASE; HELA CELLS; HUMAN; MITOSIS; PROTEIN KINASES; PROTO-ONCOGENE PROTEINS; SUPPORT, NON-U.S. GOV'T; SUPPORT, U.S. GOV'T, P.H.S.; ANIMALS; HUMANS; PROTEIN-SERINE-THREONINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT;

CHECKPOINT KINASE 1; ONCOPROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; PROTEIN KINASE B; PROTEIN SERINE THREONINE KINASE;

ANIMAL; ARTICLE; CATTLE; CELL CYCLE G2 PHASE; DRUG ANTAGONISM; HELA CELL; HUMAN; METABOLISM; MITOSIS;

EID: 0037018847     PISSN: 09609822     EISSN: None     Source Type: Journal    
DOI: 10.1016/S0960-9822(02)00843-6     Document Type: Article

References (13)

1. Phosphoinositide 3-kinase and the regulation of cell growth
2. The PI3K-PDK1 connection: More than just a road to PKB
3. PI3K: Downstream AKTion blocks apoptosis
4. Cellular survival: A play in three Akts
5. Dual role of phosphatidylinositol-3,4,5-trisphosphate in the activation of protein kinase B
6. Phosphoproteins are components of mitotic microtubule organizing centers
7. Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
8. Anoikis mechanisms
9. Integrin α2β1 promotes activation of protein phosphatase 2a and dephosphorylation of Akt and glycogen synthase kinase 3β
10. The DNA damage response: Putting checkpoints in perspective
11. DNA damage-induced cell-cycle arrest of hematopoietic cells is overridden by activation of the PI-3 kinase/Akt signaling pathway
12. Akt inhibits Myt1 in the signalling pathway that leads to meiotic G2/M-phase transition
13. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1