The tyrosine kinase Lck is required for CD95-independent caspase-8 activation and apoptosis in response to ionizing radiation

Oncogene

Volumn 18, Issue 35, 1999, Pages 4983-4992

  Belka, C ^a   Marini, P ^a   Lepple Wienhues, A ^a   Budach, W ^a   Jekle, A ^a   Los, M ^a   Lang, F ^a   Schulze Osthoff, K ^a   Gulbins, E ^a   Bamberg, M ^a  

^a UNIVERSITY OF TÜBINGEN   (Germany)

Author keywords

Apoptosis; Caspase 8 FLICE; Lck; Lymphoma; Tyrosine kinase

Indexed keywords

CASPASE; CASPASE 8; CYTOSTATIC AGENT; FAS ANTIGEN; PROTEIN TYROSINE KINASE; UNCLASSIFIED DRUG;

APOPTOSIS; ARTICLE; CELL DEATH; CONTROLLED STUDY; CROSS LINKING; ENZYME ACTIVATION; GENETIC TRANSFECTION; HUMAN; HUMAN CELL; IONIZING RADIATION; LYMPHOCYTE; LYMPHOMA CELL; PRIORITY JOURNAL; PROTEIN PROTEIN INTERACTION; SIGNAL TRANSDUCTION;

ANTIBODIES; ANTIGENS, CD95; APOPTOSIS; BH3 INTERACTING DOMAIN DEATH AGONIST PROTEIN; CARRIER PROTEINS; CASPASE 8; CASPASE 9; CASPASES; ENZYME ACTIVATION; ENZYME PRECURSORS; FAS LIGAND PROTEIN; GENES, DOMINANT; HUMANS; JURKAT CELLS; KINETICS; LYMPHOCYTE SPECIFIC PROTEIN TYROSINE KINASE P56(LCK); MEMBRANE GLYCOPROTEINS; MUTATION; PROTEIN PROCESSING, POST-TRANSLATIONAL; RADIATION, IONIZING; RNA, MESSENGER; SIGNAL TRANSDUCTION; SOLUBILITY; TRANSFECTION;

EID: 0033517301     PISSN: 09509232     EISSN: None     Source Type: Journal    
DOI: 10.1038/sj.onc.1202878     Document Type: Article

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