-
1
-
-
0037365789
-
ATM and related protein kinases: Safeguarding genome integrity
-
Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003;3:155-68.
-
(2003)
Nat Rev Cancer
, vol.3
, pp. 155-168
-
-
Shiloh, Y.1
-
2
-
-
0033081066
-
Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry
-
Brunet A, Roux D, Lenormand P, Dowd S, Keyse S, Pouyssegur J. Nuclear translocation of p42/p44 mitogen-activated protein kinase is required for growth factor-induced gene expression and cell cycle entry. EMBO J 1999;18:664-74.
-
(1999)
EMBO J
, vol.18
, pp. 664-674
-
-
Brunet, A.1
Roux, D.2
Lenormand, P.3
Dowd, S.4
Keyse, S.5
Pouyssegur, J.6
-
3
-
-
0026300729
-
Extracellular signal-regulated kinases: ERKs in progress
-
Cobb MH, Boulton TG, Robbins DJ. Extracellular signal-regulated kinases: ERKs in progress. Cell Regul 1991;2:965-78.
-
(1991)
Cell Regul
, vol.2
, pp. 965-978
-
-
Cobb, M.H.1
Boulton, T.G.2
Robbins, D.J.3
-
4
-
-
0030772168
-
Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation
-
Schmidt-Ullrich RK, Mikkelsen RB, Dent R et al. Radiation-induced proliferation of the human A431 squamous carcinoma cells is dependent on EGFR tyrosine phosphorylation. Oncogene 1997;15:1191-7.
-
(1997)
Oncogene
, vol.15
, pp. 1191-1197
-
-
Schmidt-Ullrich, R.K.1
Mikkelsen, R.B.2
Dent, R.3
-
5
-
-
0032044237
-
Protein phosphatases and the regulation of MAP kinase activity
-
Keyse SM. Protein phosphatases and the regulation of MAP kinase activity. Semin Cell Dev Biol 1998;9:143-52.
-
(1998)
Semin Cell Dev Biol
, vol.9
, pp. 143-152
-
-
Keyse, S.M.1
-
6
-
-
0026779540
-
Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase
-
Keyse SM, Emslie EA. Oxidative stress and heat shock induce a human gene encoding a protein-tyrosine phosphatase. Nature 1992;359:644-7.
-
(1992)
Nature
, vol.359
, pp. 644-647
-
-
Keyse, S.M.1
Emslie, E.A.2
-
7
-
-
0035853789
-
Role of ATM in oridative stress-mediated c-Jun phosphorylation in response to ionizing radiation and CdC12
-
Lee SA, Dritschilo A, Jung M. Role of ATM in oridative stress-mediated c-Jun phosphorylation in response to ionizing radiation and CdC12. J Biol Chem 2001;276:11783-90.
-
(2001)
J Biol Chem
, vol.276
, pp. 11783-11790
-
-
Lee, S.A.1
Dritschilo, A.2
Jung, M.3
-
8
-
-
31544464043
-
Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma
-
Chun PY, Feng FY, Scheurer AM, Davis MA, Lawrence TS, Nyati MK. Synergistic effects of gemcitabine and gefitinib in the treatment of head and neck carcinoma. Cancer Res 2006;66:981-8.
-
(2006)
Cancer Res
, vol.66
, pp. 981-988
-
-
Chun, P.Y.1
Feng, F.Y.2
Scheurer, A.M.3
Davis, M.A.4
Lawrence, T.S.5
Nyati, M.K.6
-
9
-
-
0842304926
-
Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo
-
Nyati MK, Maheshwari D, Hanasoge S, et al. Radiosensitization by pan ErbB inhibitor CI-1033 in vitro and in vivo. Clin Cancer Res 2004;10:691-700.
-
(2004)
Clin Cancer Res
, vol.10
, pp. 691-700
-
-
Nyati, M.K.1
Maheshwari, D.2
Hanasoge, S.3
-
10
-
-
0021244486
-
Mean inactivation dose: A useful concept for intercomparison of human cell survival curves
-
Fertil B, Dertinger H, Courdi A, Malaise EP. Mean inactivation dose: a useful concept for intercomparison of human cell survival curves. Radiat Res 1984;99:73-84.
-
(1984)
Radiat Res
, vol.99
, pp. 73-84
-
-
Fertil, B.1
Dertinger, H.2
Courdi, A.3
Malaise, E.P.4
-
11
-
-
0031743608
-
Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery
-
Zufferey R, Dull T, Mandel RJ, et al. Self-inactivating lentivirus vector for safe and efficient in vivo gene delivery. J Virol 1998;72:9873-80.
-
(1998)
J Virol
, vol.72
, pp. 9873-9880
-
-
Zufferey, R.1
Dull, T.2
Mandel, R.J.3
-
12
-
-
33846230253
-
-
Feng FY, Varambally S, Tomlins SA, et al. The role of EGFR degradation in gemcitabine-mediated cytotoxicity. Oncogene Epub 2006, Dec 4.
-
Feng FY, Varambally S, Tomlins SA, et al. The role of EGFR degradation in gemcitabine-mediated cytotoxicity. Oncogene Epub 2006, Dec 4.
-
-
-
-
13
-
-
14244255014
-
Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival
-
Wu W, Pew T, Zou M, Pang D, Conzen SD. Glucocorticoid receptor-induced MAPK phosphatase-1 (MPK-1) expression inhibits paclitaxel-associated MAPK activation and contributes to breast cancer cell survival. J Biol Chem 2005;280:4117-24.
-
(2005)
J Biol Chem
, vol.280
, pp. 4117-4124
-
-
Wu, W.1
Pew, T.2
Zou, M.3
Pang, D.4
Conzen, S.D.5
-
14
-
-
0036152581
-
EGFR-independent activation of ERK1/2 mediates growth inhibition by a PTPase antagonizing K-vitamin analog
-
Kar S, Adachi T, Carr BI. EGFR-independent activation of ERK1/2 mediates growth inhibition by a PTPase antagonizing K-vitamin analog. J Cell Physiol 2002;190:356-64.
-
(2002)
J Cell Physiol
, vol.190
, pp. 356-364
-
-
Kar, S.1
Adachi, T.2
Carr, B.I.3
-
15
-
-
0027358722
-
MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo
-
Sun H, Charles CH, Lau LF, Tonks NK. MKP-1 (3CH134), an immediate early gene product, is a dual specificity phosphatase that dephosphorylates MAP kinase in vivo. Cell 1993;75:487-93.
-
(1993)
Cell
, vol.75
, pp. 487-493
-
-
Sun, H.1
Charles, C.H.2
Lau, L.F.3
Tonks, N.K.4
-
16
-
-
0028329595
-
Radiation effects on DNA synthesis in a defined chromosomal replicon
-
Lamer JM, Lee H, Hamlin JL. Radiation effects on DNA synthesis in a defined chromosomal replicon. Mol Cell Biol 1994;14:1901-8.
-
(1994)
Mol Cell Biol
, vol.14
, pp. 1901-1908
-
-
Lamer, J.M.1
Lee, H.2
Hamlin, J.L.3
-
17
-
-
0035848819
-
The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis
-
Falck J, Mailand N, Syljuasen RG, Bartek J, Lukas J. The ATM-Chk2-Cdc25A checkpoint pathway guards against radioresistant DNA synthesis. Nature 2001;410:842-7.
-
(2001)
Nature
, vol.410
, pp. 842-847
-
-
Falck, J.1
Mailand, N.2
Syljuasen, R.G.3
Bartek, J.4
Lukas, J.5
-
18
-
-
0030797708
-
Recombinant ATM protein complements the cellular A-T phenotype
-
Ziv Y, Bar-Shira A, Pecker I, et al. Recombinant ATM protein complements the cellular A-T phenotype. Oncogene 1997;15:159-67.
-
(1997)
Oncogene
, vol.15
, pp. 159-167
-
-
Ziv, Y.1
Bar-Shira, A.2
Pecker, I.3
-
19
-
-
0027306121
-
The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts
-
Alessi DR, Smythe C, Keyse SM. The human CL100 gene encodes a Tyr/Thr-protein phosphatase which potently and specifically inactivates MAP kinase and suppresses its activation by oncogenic ras in Xenopus oocyte extracts. Oncogene 1993;8:2015-20.
-
(1993)
Oncogene
, vol.8
, pp. 2015-2020
-
-
Alessi, D.R.1
Smythe, C.2
Keyse, S.M.3
-
20
-
-
0035844140
-
Distinct binding determinants for ERK2/p38α and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1
-
Slack DN, Seternes OM, Gabrielsen M, Keyse SM. Distinct binding determinants for ERK2/p38α and JNK map kinases mediate catalytic activation and substrate selectivity of map kinase phosphatase-1. J Biol Chem 2001;276:16491-500.
-
(2001)
J Biol Chem
, vol.276
, pp. 16491-16500
-
-
Slack, D.N.1
Seternes, O.M.2
Gabrielsen, M.3
Keyse, S.M.4
-
21
-
-
0034611728
-
ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway
-
Lim DS, Kim ST, Xu B, et al. ATM phosphorylates p95/nbs1 in an S-phase checkpoint pathway. Nature 2000;404:613-7.
-
(2000)
Nature
, vol.404
, pp. 613-617
-
-
Lim, D.S.1
Kim, S.T.2
Xu, B.3
-
22
-
-
0034713393
-
Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products
-
Zhao S, Weng YC, Yuan SS, et al. Functional link between ataxia-telangiectasia and Nijmegen breakage syndrome gene products. Nature 2000;405:473-7.
-
(2000)
Nature
, vol.405
, pp. 473-477
-
-
Zhao, S.1
Weng, Y.C.2
Yuan, S.S.3
-
23
-
-
0028880006
-
Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis
-
Xia Z, Dickens M, Raingeaud J, Davis RJ, Greenberg ME. Opposing effects of ERK and JNK-p38 MAP kinases on apoptosis. Science 1995;270:1326-31.
-
(1995)
Science
, vol.270
, pp. 1326-1331
-
-
Xia, Z.1
Dickens, M.2
Raingeaud, J.3
Davis, R.J.4
Greenberg, M.E.5
-
24
-
-
14444288522
-
The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling
-
Huang HS, Nagane M, Klingbeil CK, et al. The enhanced tumorigenic activity of a mutant epidermal growth factor receptor common in human cancers is mediated by threshold levels of constitutive tyrosine phosphorylation and unattenuated signaling. J Biol Chem 1997;272:2927-35.
-
(1997)
J Biol Chem
, vol.272
, pp. 2927-2935
-
-
Huang, H.S.1
Nagane, M.2
Klingbeil, C.K.3
-
25
-
-
85047699658
-
ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage
-
Bar-Shira A, Rashi-Elkeles S, Zlochover L, et al. ATM-dependent activation of the gene encoding MAP kinase phosphatase 5 by radiomimetic DNA damage. Oncogene 2002;21:849-55.
-
(2002)
Oncogene
, vol.21
, pp. 849-855
-
-
Bar-Shira, A.1
Rashi-Elkeles, S.2
Zlochover, L.3
-
26
-
-
0032984348
-
Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo
-
Sebolt-Leopold JS, Dudley DT, Herrera R, et al. Blockade of the MAP kinase pathway suppresses growth of colon tumors in vivo. Nat Med 1999;5:810-6.
-
(1999)
Nat Med
, vol.5
, pp. 810-816
-
-
Sebolt-Leopold, J.S.1
Dudley, D.T.2
Herrera, R.3
-
27
-
-
0030860784
-
Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype
-
Zhang N, Chen P, Khanna KK, et al. Isolation of full-length ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype. Proc Natl Acad Sci USA 1997;94:8021-6.
-
(1997)
Proc Natl Acad Sci USA
, vol.94
, pp. 8021-8026
-
-
Zhang, N.1
Chen, P.2
Khanna, K.K.3
-
28
-
-
0037102275
-
Phosphorylation of serine 1387 in Brcal is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation
-
Xu B, O'Donnell AH, Kim ST, Kastan MB. Phosphorylation of serine 1387 in Brcal is specifically required for the Atm-mediated S-phase checkpoint after ionizing irradiation. Cancer Res 2002;62:4588-91.
-
(2002)
Cancer Res
, vol.62
, pp. 4588-4591
-
-
Xu, B.1
O'Donnell, A.H.2
Kim, S.T.3
Kastan, M.B.4
|