A protein phosphatase feedback mechanism regulates the basal phosphorylation of Chk2 kinase in the absence of DNA damage

Biochimica et Biophysica Acta - Molecular Cell Research

Volumn 1803, Issue 10, 2010, Pages 1213-1223

  Carlessi, Luigi ^a   Buscemi, Giacomo ^a   Fontanella, Enrico ^a   Delia, Domenico ^a  

^a NATIONAL CANCER INSTITUTE   (Italy)

Author keywords

Cell cycle checkpoints; Chk2; DNA damage responses; Kinase inhibitors; Protein phosphatases

Indexed keywords

ATM PROTEIN; CHECKPOINT KINASE 2; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASE; SERINE; SMALL INTERFERING RNA; THREONINE; ATM PROTEIN, HUMAN; CELL CYCLE PROTEIN; CHEK2 PROTEIN, HUMAN; DNA BINDING PROTEIN; ENZYME INHIBITOR; PHOSPHOPROTEIN PHOSPHATASE 1; PHOSPHOPROTEIN PHOSPHATASE 2; PROTEIN PHOSPHATASE 2C; PROTEIN SERINE THREONINE KINASE; THIAZOLE DERIVATIVE; TUMOR SUPPRESSOR PROTEIN; VRX0466617;

ARTICLE; AUTOPHOSPHORYLATION; CELL CYCLE PHASE; CELL LINE; CONTROLLED STUDY; DNA DAMAGE; ENZYME PHOSPHORYLATION; FEEDBACK SYSTEM; HUMAN; HUMAN CELL; PRIORITY JOURNAL; REGULATORY MECHANISM; ANTAGONISTS AND INHIBITORS; BIOLOGICAL MODEL; DRUG EFFECTS; GENETICS; METABOLISM; PHOSPHORYLATION; RNA INTERFERENCE; TUMOR CELL LINE; WESTERN BLOTTING;

BLOTTING, WESTERN; CELL CYCLE PROTEINS; CELL LINE; CELL LINE, TUMOR; DNA DAMAGE; DNA-BINDING PROTEINS; ENZYME INHIBITORS; FEEDBACK, PHYSIOLOGICAL; HUMANS; MODELS, BIOLOGICAL; OKADAIC ACID; PHOSPHOPROTEIN PHOSPHATASES; PHOSPHORYLATION; PROTEIN PHOSPHATASE 1; PROTEIN PHOSPHATASE 2; PROTEIN-SERINE-THREONINE KINASES; RNA INTERFERENCE; THIAZOLES; THREONINE; TUMOR SUPPRESSOR PROTEINS; ATAXIA TELANGIECTASIA MUTATED PROTEINS; CHECKPOINT KINASE 2;

EID: 77955665512     PISSN: 01674889     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.bbamcr.2010.06.002     Document Type: Article

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