메뉴 건너뛰기




Volumn 1, Issue 8, 2003, Pages 598-609

Regulation of the Chk2 protein kinase by oligomerization-mediated cis- and trans-phosphorylation

Author keywords

[No Author keywords available]

Indexed keywords

CHECKPOINT KINASE 2; ISOLEUCINE; PROTEIN SERINE THREONINE KINASE; THREONINE; UNCLASSIFIED DRUG;

EID: 0037795780     PISSN: 15417786     EISSN: None     Source Type: Journal    
DOI: None     Document Type: Article
Times cited : (138)

References (33)
  • 1
    • 0029808466 scopus 로고    scopus 로고
    • Cell cycle checkpoints: Preventing an identity crisis
    • Elledge. S. J. Cell cycle checkpoints: preventing an identity crisis. Science, 274: 1664-1672, 1996.
    • (1996) Science , vol.274 , pp. 1664-1672
    • Elledge, S.J.1
  • 3
    • 9244229490 scopus 로고    scopus 로고
    • cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein
    • Cimprich, K. A., Shin, T. B., Keith, C. T., and Schreiber, S. L. cDNA cloning and gene mapping of a candidate human cell cycle checkpoint protein. Proc. Natl. Acad. Sci. USA, 93: 2850-2855, 1996.
    • (1996) Proc. Natl. Acad. Sci. USA , vol.93 , pp. 2850-2855
    • Cimprich, K.A.1    Shin, T.B.2    Keith, C.T.3    Schreiber, S.L.4
  • 4
    • 0031466618 scopus 로고    scopus 로고
    • Ataxia-telangiectasia and Nijmegen breakage syndrome: Related disorders but genes apart
    • Shiloh, Y. Ataxia-telangiectasia and Nijmegen breakage syndrome: related disorders but genes apart. Annu. Rev. Genet., 31: 635-662, 1997.
    • (1997) Annu. Rev. Genet. , vol.31 , pp. 635-662
    • Shiloh, Y.1
  • 9
    • 0032484084 scopus 로고    scopus 로고
    • Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
    • Matsuoka, S., Huang, M., and Elledge, S. J. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science, 282: 1893-1897, 1998.
    • (1998) Science , vol.282 , pp. 1893-1897
    • Matsuoka, S.1    Huang, M.2    Elledge, S.J.3
  • 10
    • 0034142325 scopus 로고    scopus 로고
    • Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53
    • Chehab, N. H., Malikzay, A., Appel, M., and Halazonetis, T. D. Chk2/hCds1 functions as a DNA damage checkpoint in G1 by stabilizing p53. Genes Dev., 14: 278-288, 2000.
    • (2000) Genes Dev. , vol.14 , pp. 278-288
    • Chehab, N.H.1    Malikzay, A.2    Appel, M.3    Halazonetis, T.D.4
  • 14
    • 0034326802 scopus 로고    scopus 로고
    • Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation
    • Ahn, J-Y., Schwarz, J. K., Piwnica-Worms, H., and Canman, C. E. Threonine 68 phosphorylation by ataxia telangiectasia mutated is required for efficient activation of Chk2 in response to ionizing radiation. Cancer Res., 60: 5934-5936, 2000.
    • (2000) Cancer Res. , vol.60 , pp. 5934-5936
    • Ahn, J.-Y.1    Schwarz, J.K.2    Piwnica-Worms, H.3    Canman, C.E.4
  • 16
    • 0034306332 scopus 로고    scopus 로고
    • Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1
    • Melchionna, R., Chen, X. B., Blasina, A., and McGowan, C. H. Threonine 68 is required for radiation-induced phosphorylation and activation of Cds1. Nat. Cell Biol., 2: 762-765, 2000.
    • (2000) Nat. Cell Biol. , vol.2 , pp. 762-765
    • Melchionna, R.1    Chen, X.B.2    Blasina, A.3    McGowan, C.H.4
  • 18
    • 0035839526 scopus 로고    scopus 로고
    • The hCds1 (Chk2)-FHA domain is essential for a chain of phosphorylation events on hCds1 that is induced by ionizing radiation
    • Lee, C-H. and Chung, J. H. The hCds1 (Chk2)-FHA domain is essential for a chain of phosphorylation events on hCds1 that is induced by ionizing radiation. J. Biol. Chem., 276: 30537-30541, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 30537-30541
    • Lee, C.-H.1    Chung, J.H.2
  • 19
    • 0033197541 scopus 로고    scopus 로고
    • The FHA domain is a modular phosphopeptide recognition motif
    • Durocher, D., Henckel, J., Fersht, A. R., and Jackson, S. P. The FHA domain is a modular phosphopeptide recognition motif. Mol. Cell, 4: 387-394, 1999.
    • (1999) Mol. Cell , vol.4 , pp. 387-394
    • Durocher, D.1    Henckel, J.2    Fersht, A.R.3    Jackson, S.P.4
  • 20
    • 0033638454 scopus 로고    scopus 로고
    • The molecular basis of FHA domain: Phosphopeptide binding specificity and implications for phosph-dependent signaling mechanisms
    • Durocher, D., Taylor, I. A., Sarbassova, D., Haire, L. F., Westcott, S. L., Jackson, S. P., Smerdon, S. J., and Yaffe, S. P. The molecular basis of FHA domain: phosphopeptide binding specificity and implications for phosph-dependent signaling mechanisms. Mol. Cell, 6, 1169-1182, 2000.
    • (2000) Mol. Cell , vol.6 , pp. 1169-1182
    • Durocher, D.1    Taylor, I.A.2    Sarbassova, D.3    Haire, L.F.4    Westcott, S.L.5    Jackson, S.P.6    Smerdon, S.J.7    Yaffe, S.P.8
  • 21
    • 0036285705 scopus 로고    scopus 로고
    • Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2
    • Li, J., Williams, B. L., Haire, L. F., Goldberg, M., Wilker, E., Durocher, D., Yaffe, M. B., Jackson, S. P., and Smerdon, S. J. Structural and functional versatility of the FHA domain in DNA-damage signaling by the tumor suppressor kinase Chk2. Mol. Cell, 9: 1045-1054, 2002.
    • (2002) Mol. Cell , vol.9 , pp. 1045-1054
    • Li, J.1    Williams, B.L.2    Haire, L.F.3    Goldberg, M.4    Wilker, E.5    Durocher, D.6    Yaffe, M.B.7    Jackson, S.P.8    Smerdon, S.J.9
  • 22
    • 0037205422 scopus 로고    scopus 로고
    • Phosphorylation of Threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated (FHA) domain
    • Ahn, J-Y., Li, X., Davis, H. L., and Canman, C. E. Phosphorylation of Threonine 68 promotes oligomerization and autophosphorylation of the Chk2 protein kinase via the forkhead-associated (FHA) domain. J. Biol. Chem., 277: 19389-19395, 2002.
    • (2002) J. Biol. Chem. , vol.277 , pp. 19389-19395
    • Ahn, J.-Y.1    Li, X.2    Davis, H.L.3    Canman, C.E.4
  • 23
    • 0036258583 scopus 로고    scopus 로고
    • Chk2 activation and phosphorylation-dependent oligomerization
    • Xu, X., Tsvetkov, L. M., and Stern, D. F. Chk2 activation and phosphorylation-dependent oligomerization. Mol. Cell. Biol., 22: 4419-4432, 2002.
    • (2002) Mol. Cell. Biol. , vol.22 , pp. 4419-4432
    • Xu, X.1    Tsvetkov, L.M.2    Stern, D.F.3
  • 24
    • 0034881760 scopus 로고    scopus 로고
    • Budding yeast Rad9 is an ATP-dependent Rad53 activating machine
    • Gilbert, C. S., Green, C. M., and Lowndes, N. F. Budding yeast Rad9 is an ATP-dependent Rad53 activating machine. Mol. Cell, 8: 129-136, 2001.
    • (2001) Mol. Cell , vol.8 , pp. 129-136
    • Gilbert, C.S.1    Green, C.M.2    Lowndes, N.F.3
  • 26
    • 0035951809 scopus 로고    scopus 로고
    • Characterization of tumor-associated Chk2 mutations
    • Wu, X., Webster, S. R., and Chen, J. Characterization of tumor-associated Chk2 mutations. J. Biol. Chem., 276: 2971-2974, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 2971-2974
    • Wu, X.1    Webster, S.R.2    Chen, J.3
  • 27
    • 0035930536 scopus 로고    scopus 로고
    • Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks
    • Ward, I. M., Wu, X., and Chen, J. Threonine 68 of Chk2 is phosphorylated at sites of DNA strand breaks. J. Biol. Chem., 276: 47755-47758, 2001.
    • (2001) J. Biol. Chem. , vol.276 , pp. 47755-47758
    • Ward, I.M.1    Wu, X.2    Chen, J.3
  • 28
    • 0037341599 scopus 로고    scopus 로고
    • Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage
    • Lukas, C., Falck, J., Bartkova, J., Bartek, J., and Lukas, J. Distinct spatiotemporal dynamics of mammalian checkpoint regulators induced by DNA damage. Nat. Cell Biol., 5: 255-260, 2003.
    • (2003) Nat. Cell Biol. , vol.5 , pp. 255-260
    • Lukas, C.1    Falck, J.2    Bartkova, J.3    Bartek, J.4    Lukas, J.5
  • 29
    • 0037424258 scopus 로고    scopus 로고
    • Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody
    • Tsvetkov, L. M., Xu, X., Li, J., and Stem, D. F. Polo-like kinase 1 and Chk2 interact and co-localize to centrosomes and the midbody. J. Biol. Chem., 278: 8468-8475, 2003.
    • (2003) J. Biol. Chem. , vol.278 , pp. 8468-8475
    • Tsvetkov, L.M.1    Xu, X.2    Li, J.3    Stem, D.F.4
  • 30
  • 31
    • 0028332389 scopus 로고
    • Phosphopeptide mapping and phosphoamino acid analysis by electrophoresis and chromatography on thin-layer cellulose plates
    • van der Geer, P. and Hunter, T. Phosphopeptide mapping and phosphoamino acid analysis by electrophoresis and chromatography on thin-layer cellulose plates. Electrophoresis, 15: 544-554, 1994.
    • (1994) Electrophoresis , vol.15 , pp. 544-554
    • Van der Geer, P.1    Hunter, T.2
  • 32
    • 0028149892 scopus 로고
    • Purification ofa serine kinase that associates with and phosphorylates human Cdc25C on serine 216
    • Ogg, S., Gabrielli, B., and Piwnica-Worms, H. Purification ofa serine kinase that associates with and phosphorylates human Cdc25C on serine 216. J. Biol. Chem., 269: 30461-30469, 1994.
    • (1994) J. Biol. Chem. , vol.269 , pp. 30461-30469
    • Ogg, S.1    Gabrielli, B.2    Piwnica-Worms, H.3


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.