The TSC1-2 tumor suppressor controls insulin-PI3K signaling via regulation of IRS proteins

Journal of Cell Biology

Volumn 166, Issue 2, 2004, Pages 213-223

  Harrington, Laura S ^a   Findlay, Greg M ^a   Gray, Alex ^b   Tolkacheva, Tatiana ^a   Wigfield, Simon ^a   Rebholz, Heike ^c   Barnett, Jill ^b   Leslie, Nick R ^b   Cheng, Susan ^d   Shepherd, Peter R ^d   Gout, Ivan ^c   Downes, C Peter ^b   Lamb, Richard F ^a  

^a INSTITUTE OF CANCER RESEARCH   (United Kingdom)

^b UNIVERSITY OF DUNDEE   (United Kingdom)

^c ROYAL FREE AND UNIVERSITY COLLEGE MEDICAL SCHOOL   (United Kingdom)

^d UNIVERSITY COLLEGE LONDON   (United Kingdom)

Author keywords

6K; Nsulin; PI3K; RS proteins; TSC1 2

Indexed keywords

INSULIN; INSULIN RECEPTOR; INSULIN RECEPTOR SUBSTRATE; MUTANT PROTEIN; PHOSPHATIDYLINOSITOL 3 KINASE; PROTEIN KINASE; S6 KINASE; SOMATOMEDIN; TUBERIN; TUMOR SUPPRESSOR PROTEIN; UNCLASSIFIED DRUG;

ANIMAL CELL; ARTICLE; CELL ASSAY; CELL GROWTH; CELL MIGRATION; CELL PROLIFERATION; CELL SURVIVAL; CONTROLLED STUDY; DOWN REGULATION; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ASSAY; ENZYME REGULATION; GENE EXPRESSION REGULATION; GENE REPRESSION; GROWTH INHIBITION; MOUSE; NONHUMAN; PRIORITY JOURNAL; PROTEIN DETERMINATION; PROTEIN FUNCTION; PROTEIN PHOSPHORYLATION; REGULATORY MECHANISM; SIGNAL TRANSDUCTION; TRANSCRIPTION REGULATION; TUMOR GROWTH;

ANIMALIA;

EID: 3342958797     PISSN: 00219525     EISSN: None     Source Type: Journal    
DOI: 10.1083/jcb.200403069     Document Type: Article

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