메뉴 건너뛰기




Volumn 24, Issue 5, 2004, Pages 1823-1835

ATM and the Catalytic Subunit of DNA-Dependent Protein Kinase Activate NF-κB through a Common MEK/Extracellular Signal-Regulated Kinase/p90 rsk Signaling Pathway in Response to Distinct Forms of DNA Damage

Author keywords

[No Author keywords available]

Indexed keywords

ANTHRACYCLINE DERIVATIVE; ATM PROTEIN; DNA; DNA DEPENDENT PROTEIN KINASE; DOXORUBICIN; DOXORUBICIN DERIVATIVE; I KAPPA B KINASE; I KAPPA B KINASE 2; IMMUNOGLOBULIN ENHANCER BINDING PROTEIN; MITOGEN ACTIVATED PROTEIN KINASE; N BENZYLDOXORUBICIN; PHOSPHATIDYLINOSITOL KINASE; PROTEIN; PROTEIN P53; PROTEIN P90; UNCLASSIFIED DRUG;

EID: 1342304040     PISSN: 02707306     EISSN: None     Source Type: Journal    
DOI: 10.1128/MCB.24.5.1823-1835.2004     Document Type: Article
Times cited : (119)

References (55)
  • 1
    • 0033623830 scopus 로고    scopus 로고
    • Role of the IκB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells
    • Arsura, M., F. Mercurio, A. L. Oliver, S. S. Thorgeirsson, and G. E. Sonenshein. 2000. Role of the IκB kinase complex in oncogenic Ras- and Raf-mediated transformation of rat liver epithelial cells. Mol. Cell. Biol. 20:5381-5391.
    • (2000) Mol. Cell. Biol. , vol.20 , pp. 5381-5391
    • Arsura, M.1    Mercurio, F.2    Oliver, A.L.3    Thorgeirsson, S.S.4    Sonenshein, G.E.5
  • 3
    • 0030198199 scopus 로고    scopus 로고
    • TGF β1 inhibits NF-κB/Rel activity inducing apoptosis of B cells: Transcriptional activation of IκBα
    • Arsura, M., M. Wu, and G. E. Sonenshein. 1996. TGF β1 inhibits NF-κB/Rel activity inducing apoptosis of B cells: transcriptional activation of IκBα. Immunity 5:31-40.
    • (1996) Immunity , vol.5 , pp. 31-40
    • Arsura, M.1    Wu, M.2    Sonenshein, G.E.3
  • 4
    • 0037472924 scopus 로고    scopus 로고
    • DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation
    • Bakkenist, C. J., and M. B. Kastan. 2003. DNA damage activates ATM through intermolecular autophosphorylation and dimer dissociation. Nature 421:499-506.
    • (2003) Nature , vol.421 , pp. 499-506
    • Bakkenist, C.J.1    Kastan, M.B.2
  • 5
    • 0029059060 scopus 로고
    • Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB
    • Beg, A. A., W. C. Sha, R. T. Bronson, S. Ghosh, and D. Baltimore. 1995. Embryonic lethality and liver degeneration in mice lacking the RelA component of NF-κB. Nature 376:167-170.
    • (1995) Nature , vol.376 , pp. 167-170
    • Beg, A.A.1    Sha, W.C.2    Bronson, R.T.3    Ghosh, S.4    Baltimore, D.5
  • 6
    • 0035502956 scopus 로고    scopus 로고
    • Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: A brake to apoptosis in HeLa human carcinoma cells
    • Bottero, V., V. Busuttil, A. Loubat, N. Magne, J. L. Fischel, G. Milano, and J. F. Peyron. 2001. Activation of nuclear factor κB through the IKK complex by the topoisomerase poisons SN38 and doxorubicin: a brake to apoptosis in HeLa human carcinoma cells. Cancer Res. 61:7785-7791.
    • (2001) Cancer Res. , vol.61 , pp. 7785-7791
    • Bottero, V.1    Busuttil, V.2    Loubat, A.3    Magne, N.4    Fischel, J.L.5    Milano, G.6    Peyron, J.F.7
  • 7
    • 0028986075 scopus 로고
    • Control of IκB-α proteolysis by site-specific, signal-induced phosphorylation
    • Brown, K., S. Gerstberger, L. Carlson, G. Franzoso, and U. Siebenlist. 1995. Control of IκB-α proteolysis by site-specific, signal-induced phosphorylation. Science 267:1485-1488.
    • (1995) Science , vol.267 , pp. 1485-1488
    • Brown, K.1    Gerstberger, S.2    Carlson, L.3    Franzoso, G.4    Siebenlist, U.5
  • 8
    • 0037106180 scopus 로고    scopus 로고
    • Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks
    • Chan, D. W., B. P. Chen, S. Prithivirajsingh, A. Kurimasa, M. D. Story, J. Qin, and D. J. Chen. 2002. Autophosphorylation of the DNA-dependent protein kinase catalytic subunit is required for rejoining of DNA double-strand breaks. Genes Dev. 16:2333-2338.
    • (2002) Genes Dev. , vol.16 , pp. 2333-2338
    • Chan, D.W.1    Chen, B.P.2    Prithivirajsingh, S.3    Kurimasa, A.4    Story, M.D.5    Qin, J.6    Chen, D.J.7
  • 9
    • 0043027001 scopus 로고    scopus 로고
    • HSV-1 amplicon vector-mediated expression of ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype
    • Cortes, M. L., C. J. Bakkenist, M. V. Di Maria, M. B. Kastan, and X. O. Breakefield. 2003. HSV-1 amplicon vector-mediated expression of ATM cDNA and correction of the ataxia-telangiectasia cellular phenotype. Gene Ther. 10:1321-1327.
    • (2003) Gene Ther. , vol.10 , pp. 1321-1327
    • Cortes, M.L.1    Bakkenist, C.J.2    Di Maria, M.V.3    Kastan, M.B.4    Breakefield, X.O.5
  • 10
    • 0030610472 scopus 로고    scopus 로고
    • Activation of NF-κB by antineoplastic agents. Role of protein kinase C
    • Das, K. C., and C. W. White. 1997. Activation of NF-κB by antineoplastic agents. Role of protein kinase C. J. Biol. Chem. 272:14914-14920.
    • (1997) J. Biol. Chem. , vol.272 , pp. 14914-14920
    • Das, K.C.1    White, C.W.2
  • 11
    • 0025302552 scopus 로고
    • Interaction of an NF-κB-like factor with a site upstream of the c-myc promoter
    • Duyao, M. P., A. J. Buckler, and G. E. Sonenshein. 1990. Interaction of an NF-κB-like factor with a site upstream of the c-myc promoter. Proc. Natl. Acad. Sci. USA 87:4727-4731.
    • (1990) Proc. Natl. Acad. Sci. USA , vol.87 , pp. 4727-4731
    • Duyao, M.P.1    Buckler, A.J.2    Sonenshein, G.E.3
  • 13
    • 0030851775 scopus 로고    scopus 로고
    • The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IκBα and stimulates its degradation in vitro
    • Ghoda, L., X. Lin, and W. C. Greene. 1997. The 90-kDa ribosomal S6 kinase (pp90rsk) phosphorylates the N-terminal regulatory domain of IκBα and stimulates its degradation in vitro. J. Biol. Chem. 272:21281-21288.
    • (1997) J. Biol. Chem. , vol.272 , pp. 21281-21288
    • Ghoda, L.1    Lin, X.2    Greene, W.C.3
  • 14
    • 0026303190 scopus 로고
    • p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts
    • Harvey, D. M., and A. J. Levine. 1991. p53 alteration is a common event in the spontaneous immortalization of primary BALB/c murine embryo fibroblasts. Genes Dev. 5:2375-2385.
    • (1991) Genes Dev. , vol.5 , pp. 2375-2385
    • Harvey, D.M.1    Levine, A.J.2
  • 16
    • 0037382303 scopus 로고    scopus 로고
    • The death domain kinase RIP has an essential role in DNA damage-induced NF-κB activation
    • Hur, G. M., J. Lewis, Q. Yang, Y. Lin, H. Nakano, S. Nedospasov, and Z. G. Liu. 2003. The death domain kinase RIP has an essential role in DNA damage-induced NF-κB activation. Genes Dev. 17:873-882.
    • (2003) Genes Dev. , vol.17 , pp. 873-882
    • Hur, G.M.1    Lewis, J.2    Yang, Q.3    Lin, Y.4    Nakano, H.5    Nedospasov, S.6    Liu, Z.G.7
  • 17
    • 0034576494 scopus 로고    scopus 로고
    • The many substrates and functions of ATM
    • Kastan, M. B., and D. S. Lim. 2000. The many substrates and functions of ATM. Nat. Rev. Mol. Cell Biol. 1:179-186.
    • (2000) Nat. Rev. Mol. Cell Biol. , vol.1 , pp. 179-186
    • Kastan, M.B.1    Lim, D.S.2
  • 19
    • 0028177404 scopus 로고
    • Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation
    • Kharbanda, S., A. Saleem, T. Shafman, Y. Emoto, R. Weichselbaum, and D. Kufe. 1994. Activation of the pp90rsk and mitogen-activated serine/threonine protein kinases by ionizing radiation. Proc. Natl. Acad. Sci. USA 91:5416-5420.
    • (1994) Proc. Natl. Acad. Sci. USA , vol.91 , pp. 5416-5420
    • Kharbanda, S.1    Saleem, A.2    Shafman, T.3    Emoto, Y.4    Weichselbaum, R.5    Kufe, D.6
  • 20
    • 0032443366 scopus 로고    scopus 로고
    • Determination of cell fate by c-Abl activation in the response to DNA damage
    • Kharbanda, S., Z. M. Yuan, R. Weichselbaum, and D. Kufe. 1998. Determination of cell fate by c-Abl activation in the response to DNA damage. Oncogene 17:3309-3318.
    • (1998) Oncogene , vol.17 , pp. 3309-3318
    • Kharbanda, S.1    Yuan, Z.M.2    Weichselbaum, R.3    Kufe, D.4
  • 21
    • 0033621392 scopus 로고    scopus 로고
    • Substrate specificities and identification of putative substrates of ATM kinase family members
    • Kim, S. T., D. S. Lim, C. E. Canman, and M. B. Kastan. 1999. Substrate specificities and identification of putative substrates of ATM kinase family members. J. Biol. Chem. 274:37538-37543.
    • (1999) J. Biol. Chem. , vol.274 , pp. 37538-37543
    • Kim, S.T.1    Lim, D.S.2    Canman, C.E.3    Kastan, M.B.4
  • 22
    • 0032938747 scopus 로고    scopus 로고
    • Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining
    • Kurimasa, A., S. Kumano, N. V. Boubnov, M. D. Story, C. S. Tung, S. R. Peterson, and D. J. Chen. 1999. Requirement for the kinase activity of human DNA-dependent protein kinase catalytic subunit in DNA strand break rejoining. Mol. Cell. Biol. 19:3877-3884.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 3877-3884
    • Kurimasa, A.1    Kumano, S.2    Boubnov, N.V.3    Story, M.D.4    Tung, C.S.5    Peterson, S.R.6    Chen, D.J.7
  • 23
    • 0032484194 scopus 로고    scopus 로고
    • Impaired ionizing radiation-induced activation of a nuclear signal essential for phosphorylation of c-Jun by dually phosphorylated c-Jun amino-terminal kinases in ataxia telangiectasia fibroblasts
    • Lee, S. A., A. Dritschilo, and M. Jung. 1998. Impaired ionizing radiation-induced activation of a nuclear signal essential for phosphorylation of c-Jun by dually phosphorylated c-Jun amino-terminal kinases in ataxia telangiectasia fibroblasts. J. Biol. Chem. 273:32889-32894.
    • (1998) J. Biol. Chem. , vol.273 , pp. 32889-32894
    • Lee, S.A.1    Dritschilo, A.2    Jung, M.3
  • 24
    • 0032497587 scopus 로고    scopus 로고
    • A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB
    • Lee, S. J., A. Dimtchev, M. F. Lavin, A. Dritschilo, and M. Jung. 1998. A novel ionizing radiation-induced signaling pathway that activates the transcription factor NF-κB. Oncogene 17:1821-1826.
    • (1998) Oncogene , vol.17 , pp. 1821-1826
    • Lee, S.J.1    Dimtchev, A.2    Lavin, M.F.3    Dritschilo, A.4    Jung, M.5
  • 25
    • 0032510596 scopus 로고    scopus 로고
    • Activation of NF-κB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells
    • Li, J. D., W. Feng, M. Gallup, J. H. Kim, J. Gum, Y. Kim, and C. Basbaum. 1998. Activation of NF-κB via a Src-dependent Ras-MAPK-pp90rsk pathway is required for Pseudomonas aeruginosa-induced mucin overproduction in epithelial cells. Proc. Natl. Acad. Sci. USA 95:5718-5723.
    • (1998) Proc. Natl. Acad. Sci. USA , vol.95 , pp. 5718-5723
    • Li, J.D.1    Feng, W.2    Gallup, M.3    Kim, J.H.4    Gum, J.5    Kim, Y.6    Basbaum, C.7
  • 26
    • 0035937809 scopus 로고    scopus 로고
    • ATM is required for IκB kinase (IKKk) activation in response to DNA double strand breaks
    • Li, N., S. Banin, H. Ouyang, G. C. Li, G. Courtois, Y. Shiloh, M. Karin, and G. Rotman. 2001. ATM is required for IκB kinase (IKKk) activation in response to DNA double strand breaks. J. Biol. Chem. 276:8898-8903.
    • (2001) J. Biol. Chem. , vol.276 , pp. 8898-8903
    • Li, N.1    Banin, S.2    Ouyang, H.3    Li, G.C.4    Courtois, G.5    Shiloh, Y.6    Karin, M.7    Rotman, G.8
  • 27
    • 0029670085 scopus 로고    scopus 로고
    • Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability
    • Lin, R., P. Beauparlant, C. Makris, S. Meloche, and J. Hiscott. 1996. Phosphorylation of IκBα in the C-terminal PEST domain by casein kinase II affects intrinsic protein stability. Mol. Cell. Biol. 16:1401-1409.
    • (1996) Mol. Cell. Biol. , vol.16 , pp. 1401-1409
    • Lin, R.1    Beauparlant, P.2    Makris, C.3    Meloche, S.4    Hiscott, J.5
  • 29
    • 0026997539 scopus 로고
    • N-benzyladriamycin-14-valerate and drug resistance: Correlation of anthracycline structural modification with intracellular accumulation and distribution in multidrug resistant cells
    • Lothstein, L., H. M. Wright, T. W. Sweatman, and M. Israel. 1992. N-benzyladriamycin-14-valerate and drug resistance: correlation of anthracycline structural modification with intracellular accumulation and distribution in multidrug resistant cells. Oncol. Res. 4:341-347.
    • (1992) Oncol. Res. , vol.4 , pp. 341-347
    • Lothstein, L.1    Wright, H.M.2    Sweatman, T.W.3    Israel, M.4
  • 30
    • 0027451668 scopus 로고
    • p53-dependent apoptosis modulates the cytotoxicity of anticancer agents
    • Lowe, S. W., H. E. Ruley, T. Jacks, and D. E. Housman. 1993. p53-dependent apoptosis modulates the cytotoxicity of anticancer agents. Cell 74:957-967.
    • (1993) Cell , vol.74 , pp. 957-967
    • Lowe, S.W.1    Ruley, H.E.2    Jacks, T.3    Housman, D.E.4
  • 31
    • 0034719680 scopus 로고    scopus 로고
    • The transcription factor NF-κB: Control of oncogenesis and cancer therapy resistance
    • Mayo, M. W., and A. S. Baldwin. 2000. The transcription factor NF-κB: control of oncogenesis and cancer therapy resistance. Biochim. Biophys. Acta 1470:M55-M62.
    • (2000) Biochim. Biophys. Acta , vol.1470
    • Mayo, M.W.1    Baldwin, A.S.2
  • 32
    • 0032939903 scopus 로고    scopus 로고
    • Multiple signals converging on NF-κB
    • Mercurio, F., and A. M. Manning. 1999. Multiple signals converging on NF-κB. Curr. Opin. Cell Biol. 11:226-232.
    • (1999) Curr. Opin. Cell Biol. , vol.11 , pp. 226-232
    • Mercurio, F.1    Manning, A.M.2
  • 35
    • 0021815615 scopus 로고
    • Establishment and characterization of a permanent pSV ori-transformed ataxia-telangiectasia cell line
    • Murnane, J. P., L. F. Fuller, and R. B. Painter. 1985. Establishment and characterization of a permanent pSV ori-transformed ataxia-telangiectasia cell line. Exp. Cell Res. 158:119-126.
    • (1985) Exp. Cell Res. , vol.158 , pp. 119-126
    • Murnane, J.P.1    Fuller, L.F.2    Painter, R.B.3
  • 36
    • 0028902932 scopus 로고
    • Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells
    • Peterson, S. R., A. Kurimasa, M. Oshimura, W. S. Dynan, E. M. Bradbury, and D. J. Chen. 1995. Loss of the catalytic subunit of the DNA-dependent protein kinase in DNA double-strand-break-repair mutant mammalian cells. Proc. Natl. Acad. Sci. USA 92:3171-3174.
    • (1995) Proc. Natl. Acad. Sci. USA , vol.92 , pp. 3171-3174
    • Peterson, S.R.1    Kurimasa, A.2    Oshimura, M.3    Dynan, W.S.4    Bradbury, E.M.5    Chen, D.J.6
  • 37
    • 0029997148 scopus 로고    scopus 로고
    • Topoisomerase poisons activate the transcription factor NF-κB in ACH-2 and CEM cells
    • Piret, B., and J. Piette. 1996. Topoisomerase poisons activate the transcription factor NF-κB in ACH-2 and CEM cells. Nucleic Acids Res. 24:4242-4248.
    • (1996) Nucleic Acids Res. , vol.24 , pp. 4242-4248
    • Piret, B.1    Piette, J.2
  • 38
    • 0033118909 scopus 로고    scopus 로고
    • The ATM protein is required for sustained activation of NF-κB following DNA damage
    • Piret, B., S. Schoonbroodt, and J. Piette. 1999. The ATM protein is required for sustained activation of NF-κB following DNA damage. Oncogene 18:2261-2271.
    • (1999) Oncogene , vol.18 , pp. 2261-2271
    • Piret, B.1    Schoonbroodt, S.2    Piette, J.3
  • 41
    • 0034689773 scopus 로고    scopus 로고
    • Role of NF-κB in p53-mediated programmed cell death
    • Ryan, K. M., M. K. Ernst, N. R. Rice, and K. H. Vousden. 2000. Role of NF-κB in p53-mediated programmed cell death. Nature 404:892-897.
    • (2000) Nature , vol.404 , pp. 892-897
    • Ryan, K.M.1    Ernst, M.K.2    Rice, N.R.3    Vousden, K.H.4
  • 42
    • 0034991897 scopus 로고    scopus 로고
    • Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome
    • Saeki, Y., C. Fraefel, T. Ichikawa, X. O. Breakefield, and E. A. Chiocca. 2001. Improved helper virus-free packaging system for HSV amplicon vectors using an ICP27-deleted, oversized HSV-1 DNA in a bacterial artificial chromosome. Mol. Ther. 3:591-601.
    • (2001) Mol. Ther. , vol.3 , pp. 591-601
    • Saeki, Y.1    Fraefel, C.2    Ichikawa, T.3    Breakefield, X.O.4    Chiocca, E.A.5
  • 44
    • 0032189483 scopus 로고    scopus 로고
    • Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin
    • Sarkaria, J. N., R. S. Tibbetts, E. C. Busby, A. P. Kennedy, D. E. Hill, and R. T. Abraham. 1998. Inhibition of phosphoinositide 3-kinase related kinases by the radiosensitizing agent wortmannin. Cancer Res. 58:4375-4382.
    • (1998) Cancer Res. , vol.58 , pp. 4375-4382
    • Sarkaria, J.N.1    Tibbetts, R.S.2    Busby, E.C.3    Kennedy, A.P.4    Hill, D.E.5    Abraham, R.T.6
  • 46
    • 0029134790 scopus 로고
    • Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation
    • Shafman, T. D., A. Saleem, J. Kyriakis, R. Weichselbaum, S. Kharbanda, and D. W. Kufe. 1995. Defective induction of stress-activated protein kinase activity in ataxia-telangiectasia cells exposed to ionizing radiation. Cancer Res. 55:3242-3245.
    • (1995) Cancer Res. , vol.55 , pp. 3242-3245
    • Shafman, T.D.1    Saleem, A.2    Kyriakis, J.3    Weichselbaum, R.4    Kharbanda, S.5    Kufe, D.W.6
  • 47
    • 0034798285 scopus 로고    scopus 로고
    • ATM: Genome stability, neuronal development, and cancer cross paths
    • Shiloh, Y., and M. B. Kastan. 2001. ATM: genome stability, neuronal development, and cancer cross paths. Adv. Cancer Res. 83:209-254.
    • (2001) Adv. Cancer Res. , vol.83 , pp. 209-254
    • Shiloh, Y.1    Kastan, M.B.2
  • 48
    • 0037066686 scopus 로고    scopus 로고
    • ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53
    • Tang, D., D. Wu, A. Hirao, J. M. Lahti, L. Liu, B. Mazza, V. J. Kidd, T. W. Mak, and A. J. Ingram. 2002. ERK activation mediates cell cycle arrest and apoptosis after DNA damage independently of p53. J. Biol. Chem. 277:12710-12717.
    • (2002) J. Biol. Chem. , vol.277 , pp. 12710-12717
    • Tang, D.1    Wu, D.2    Hirao, A.3    Lahti, J.M.4    Liu, L.5    Mazza, B.6    Kidd, V.J.7    Mak, T.W.8    Ingram, A.J.9
  • 49
    • 0036599406 scopus 로고    scopus 로고
    • p53 stabilization is decreased upon NFκB activation: A role for NFκB in acquisition of resistance to chemotherapy
    • Tergaonkar, V., M. Pando, O. Vafa, G. Wahl, and I. Verma. 2002. p53 stabilization is decreased upon NFκB activation: a role for NFκB in acquisition of resistance to chemotherapy. Cancer Cell 1:493-503.
    • (2002) Cancer Cell , vol.1 , pp. 493-503
    • Tergaonkar, V.1    Pando, M.2    Vafa, O.3    Wahl, G.4    Verma, I.5
  • 50
    • 0034528256 scopus 로고    scopus 로고
    • Protein kinase C-alpha is an upstream activator of the IκB kinase complex in the TPA signal transduction pathway to NF-κB in U2OS cells
    • Vertegaal, A. C., H. B. Kuiperij, S. Yamaoka, G. Courtois, A. J. van der Eb, and A. Zantema. 2000. Protein kinase C-alpha is an upstream activator of the IκB kinase complex in the TPA signal transduction pathway to NF-κB in U2OS cells. Cell. Signal. 12:759-768.
    • (2000) Cell. Signal. , vol.12 , pp. 759-768
    • Vertegaal, A.C.1    Kuiperij, H.B.2    Yamaoka, S.3    Courtois, G.4    Van Der Eb, A.J.5    Zantema, A.6
  • 51
    • 0032905030 scopus 로고    scopus 로고
    • Control of inducible chemoresistance: Enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB
    • Wang, C. Y., J. C. Cusack, Jr., R. Liu, and A. S. Baldwin, Jr. 1999. Control of inducible chemoresistance: enhanced anti-tumor therapy through increased apoptosis by inhibition of NF-κB. Nat. Med. 5:412-417.
    • (1999) Nat. Med. , vol.5 , pp. 412-417
    • Wang, C.Y.1    Cusack Jr., J.C.2    Liu, R.3    Baldwin Jr., A.S.4
  • 52
    • 0032588317 scopus 로고    scopus 로고
    • NF-κB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis
    • Wang, C. Y., D. C. Guttridge, M. W. Mayo, and A. S. Baldwin, Jr. 1999. NF-κB induces expression of the Bcl-2 homologue A1/Bfl-1 to preferentially suppress chemotherapy-induced apoptosis. Mol. Cell. Biol. 19:5923-5929.
    • (1999) Mol. Cell. Biol. , vol.19 , pp. 5923-5929
    • Wang, C.Y.1    Guttridge, D.C.2    Mayo, M.W.3    Baldwin Jr., A.S.4


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.