메뉴 건너뛰기




Volumn 7, Issue 20, 2008, Pages 3194-3201

Never-in-mitosis related kinase 1 functions in DNA damage response and checkpoint control

Author keywords

Checkpoint control; Chromosome breaks; Mitosis; Radiation; S phase

Indexed keywords

CHECKPOINT KINASE 1; CHECKPOINT KINASE 2; DOUBLE STRANDED DNA; NEVER IN MITOSIS RELATED KINASE 1; PHOSPHOTRANSFERASE; SMALL INTERFERING RNA; UNCLASSIFIED DRUG;

EID: 54049094397     PISSN: 15384101     EISSN: 15514005     Source Type: Journal    
DOI: 10.4161/cc.7.20.6815     Document Type: Article
Times cited : (74)

References (42)
  • 1
    • 0038739131 scopus 로고    scopus 로고
    • Never say never. The NIMA-related protein kinases in mitotic control
    • O'Connell MJ, Krien MJ and Hunter T. Never say never. The NIMA-related protein kinases in mitotic control. Trends Cell Biol 2003; 13:221-8.
    • (2003) Trends Cell Biol , vol.13 , pp. 221-228
    • O'Connell, M.J.1    Krien, M.J.2    Hunter, T.3
  • 2
    • 0026671553 scopus 로고
    • The mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells
    • Letwin K, Mizzen L, Motro B, Ben-David Y, Bernstein A and Pawson TA. The mammalian dual specificity protein kinase, Nek1, is related to the NIMA cell cycle regulator and highly expressed in meiotic germ cells. EMBO J 1992; 11:3521-31.
    • (1992) EMBO J , vol.11 , pp. 3521-3531
    • Letwin, K.1    Mizzen, L.2    Motro, B.3    Ben-David, Y.4    Bernstein, A.5    Pawson, T.A.6
  • 3
    • 0032499243 scopus 로고    scopus 로고
    • Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system
    • Arama E, Yanai A, Kilfin G, Bernstein A and Motro B. Murine NIMA-related kinases are expressed in patterns suggesting distinct functions in gametogenesis and a role in the nervous system. Oncogene 1998; 16:1813-23.
    • (1998) Oncogene , vol.16 , pp. 1813-1823
    • Arama, E.1    Yanai, A.2    Kilfin, G.3    Bernstein, A.4    Motro, B.5
  • 4
    • 0034602780 scopus 로고    scopus 로고
    • Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice
    • Upadhya P, Birkenmeier EH, Birkenmeier CS, Barker JE. Mutations in a NIMA-related kinase gene, Nek1, cause pleiotropic effects including a progressive polycystic kidney disease in mice. Proc Natl Acad Sci USA 2000; 97:217-21.
    • (2000) Proc Natl Acad Sci USA , vol.97 , pp. 217-221
    • Upadhya, P.1    Birkenmeier, E.H.2    Birkenmeier, C.S.3    Barker, J.E.4
  • 6
    • 0026048594 scopus 로고
    • Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans
    • Osmani AH, McGuire SL, Osmani SA. Parallel activation of the NIMA and p34cdc2 cell cycle-regulated protein kinases is required to initiate mitosis in A. nidulans. Cell 1991; 67:283-91.
    • (1991) Cell , vol.67 , pp. 283-291
    • Osmani, A.H.1    McGuire, S.L.2    Osmani, S.A.3
  • 7
    • 0025861473 scopus 로고
    • Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint
    • Osmani AH, O'Donnell K, Pu RT, Osmani SA. Activation of the nimA protein kinase plays a unique role during mitosis that cannot be bypassed by absence of the bimE checkpoint. EMBO J 1991; 10:2669-79.
    • (1991) EMBO J , vol.10 , pp. 2669-2679
    • Osmani, A.H.1    O'Donnell, K.2    Pu, R.T.3    Osmani, S.A.4
  • 8
    • 0024299060 scopus 로고
    • Spindle formation and chromatin condensation in cells blocked at interphase by mutation of a negative cell cycle control gene
    • Osmani SA, Engle DB, Doonan JH, Morris NR. Spindle formation and chromatin condensation in cells blocked at interphase by mutation of a negative cell cycle control gene. Cell 1988; 52:241-51.
    • (1988) Cell , vol.52 , pp. 241-251
    • Osmani, S.A.1    Engle, D.B.2    Doonan, J.H.3    Morris, N.R.4
  • 9
    • 0347579850 scopus 로고    scopus 로고
    • Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation
    • Chen Y, Riley DJ, Zheng L, Chen PL, Lee WH. Phosphorylation of the mitotic regulator protein Hec1 by Nek2 kinase is essential for faithful chromosome segregation. J Biol Chem 2002; 277:49408-16.
    • (2002) J Biol Chem , vol.277 , pp. 49408-49416
    • Chen, Y.1    Riley, D.J.2    Zheng, L.3    Chen, P.L.4    Lee, W.H.5
  • 10
    • 33646839443 scopus 로고    scopus 로고
    • Nek2 kinase in chromosome instability and cancer
    • Hayward DG, Fry AM. Nek2 kinase in chromosome instability and cancer. Cancer Lett 2006; 237:155-66.
    • (2006) Cancer Lett , vol.237 , pp. 155-166
    • Hayward, D.G.1    Fry, A.M.2
  • 11
    • 0036645394 scopus 로고    scopus 로고
    • Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression
    • Roig J, Mikhailov A, Belham C, Avruch J. Nercc1, a mammalian NIMA-family kinase, binds the Ran GTPase and regulates mitotic progression. Genes Dev 2002; 16:1640-58.
    • (2002) Genes Dev , vol.16 , pp. 1640-1658
    • Roig, J.1    Mikhailov, A.2    Belham, C.3    Avruch, J.4
  • 12
    • 33750972565 scopus 로고    scopus 로고
    • Nek7 kinase is enriched at the centrosome, and is required for proper spindle assembly and mitotic progression
    • Yissachar N, Salem H, Tennenbaum T, Motro B. Nek7 kinase is enriched at the centrosome, and is required for proper spindle assembly and mitotic progression. FEBS Lett 2006; 580:6489-95.
    • (2006) FEBS Lett , vol.580 , pp. 6489-6495
    • Yissachar, N.1    Salem, H.2    Tennenbaum, T.3    Motro, B.4
  • 13
    • 1542395668 scopus 로고    scopus 로고
    • Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors
    • Bowers AJ, Boylan JF. Nek8, a NIMA family kinase member, is overexpressed in primary human breast tumors. Gene 2004; 328:135-42.
    • (2004) Gene , vol.328 , pp. 135-142
    • Bowers, A.J.1    Boylan, J.F.2
  • 14
    • 0036931712 scopus 로고    scopus 로고
    • A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish
    • Liu S, Lu W, Obara T, Kuida S, Lehoczky J, Dewar K, Drummond IA, Beier DR. A defect in a novel Nek-family kinase causes cystic kidney disease in the mouse and in zebrafish. Development 2002; 129:5839-46.
    • (2002) Development , vol.129 , pp. 5839-5846
    • Liu, S.1    Lu, W.2    Obara, T.3    Kuida, S.4    Lehoczky, J.5    Dewar, K.6    Drummond, I.A.7    Beier, D.R.8
  • 15
    • 33645904854 scopus 로고    scopus 로고
    • NIMA-related kinases defective in murine models of polycystic kidney diseases localize to primary cilia and centrosomes
    • Mahjoub MR, Trapp ML, Quarmby LM. NIMA-related kinases defective in murine models of polycystic kidney diseases localize to primary cilia and centrosomes. J Am Soc Nephrol 2005; 16:3485-9.
    • (2005) J Am Soc Nephrol , vol.16 , pp. 3485-3489
    • Mahjoub, M.R.1    Trapp, M.L.2    Quarmby, L.M.3
  • 16
    • 34250891981 scopus 로고    scopus 로고
    • The primary cilium: Keeper of the key to cell division
    • Pan J, Snell W. The primary cilium: keeper of the key to cell division. Cell 2007; 129:1255-7.
    • (2007) Cell , vol.129 , pp. 1255-1257
    • Pan, J.1    Snell, W.2
  • 17
    • 10844257527 scopus 로고    scopus 로고
    • NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response
    • Polci R, Peng A, Chen PL, Riley DJ, Chen Y. NIMA-related protein kinase 1 is involved early in the ionizing radiation-induced DNA damage response. Cancer Res 2004; 64:8800-3.
    • (2004) Cancer Res , vol.64 , pp. 8800-8803
    • Polci, R.1    Peng, A.2    Chen, P.L.3    Riley, D.J.4    Chen, Y.5
  • 18
    • 9244263076 scopus 로고    scopus 로고
    • Aneuploidy and cancer
    • Rajagopalan H, Lengauer C. Aneuploidy and cancer. Nature 2004; 432:338-41.
    • (2004) Nature , vol.432 , pp. 338-341
    • Rajagopalan, H.1    Lengauer, C.2
  • 21
    • 0033616828 scopus 로고    scopus 로고
    • A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage
    • Brown AL, Lee CH, Schwarz JK, Mitiku N, Piwnica-Worms H, Chung JH. A human Cds1-related kinase that functions downstream of ATM protein in the cellular response to DNA damage. Proc Natl Acad Sci USA 1999; 96:3745-50.
    • (1999) Proc Natl Acad Sci USA , vol.96 , pp. 3745-3750
    • Brown, A.L.1    Lee, C.H.2    Schwarz, J.K.3    Mitiku, N.4    Piwnica-Worms, H.5    Chung, J.H.6
  • 24
    • 0032484084 scopus 로고    scopus 로고
    • Linkage of ATM to cell cycle regulation by the Chk2 protein kinase
    • Matsuoka S, Huang M, Elledge SJ. Linkage of ATM to cell cycle regulation by the Chk2 protein kinase. Science 1998; 282:1893-97.
    • (1998) Science , vol.282 , pp. 1893-1897
    • Matsuoka, S.1    Huang, M.2    Elledge, S.J.3
  • 26
    • 0034967556 scopus 로고    scopus 로고
    • ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1
    • Zhao H, Piwnica-Worms H. ATR-mediated checkpoint pathways regulate phosphorylation and activation of human Chk1. Mol Cell Biol 2001; 21:4129-39.
    • (2001) Mol Cell Biol , vol.21 , pp. 4129-4139
    • Zhao, H.1    Piwnica-Worms, H.2
  • 27
    • 0030867582 scopus 로고    scopus 로고
    • Conservation of the Chk1 checkpoint pathway in mammals: Linkage of DNA damage to Cdk regulation through Cdc25
    • Sanchez Y, Wong C, Thoma RS, Richman R, Wu, Z, Piwnica-Worms H, Elledge SJ. Conservation of the Chk1 checkpoint pathway in mammals: linkage of DNA damage to Cdk regulation through Cdc25. Science 1997; 277:1497-501.
    • (1997) Science , vol.277 , pp. 1497-1501
    • Sanchez, Y.1    Wong, C.2    Thoma, R.S.3    Richman, R.4    Wu, Z.5    Piwnica-Worms, H.6    Elledge, S.J.7
  • 28
    • 33645801236 scopus 로고    scopus 로고
    • DNA-damage response pathways triggered by viral replication
    • Sinclair A, Yarranton S, Schelcher C. DNA-damage response pathways triggered by viral replication. Expert Rev Mol Med 2006; 8:1-11.
    • (2006) Expert Rev Mol Med , vol.8 , pp. 1-11
    • Sinclair, A.1    Yarranton, S.2    Schelcher, C.3
  • 29
    • 42449130956 scopus 로고    scopus 로고
    • Break-induced replication: What is it and what is it for?
    • Llorente B, Smith CE and Symington LS. Break-induced replication: what is it and what is it for? Cell Cycle 2008; 7:859-64.
    • (2008) Cell Cycle , vol.7 , pp. 859-864
    • Llorente, B.1    Smith, C.E.2    Symington, L.S.3
  • 31
    • 0020622867 scopus 로고
    • A mutation in Aspergillus nidulans that blocks the transition from interphase to prophase
    • Oakley BR, Morris NR. A mutation in Aspergillus nidulans that blocks the transition from interphase to prophase. J Cell Biol 1983; 96:1155-8.
    • (1983) J Cell Biol , vol.96 , pp. 1155-1158
    • Oakley, B.R.1    Morris, N.R.2
  • 32
    • 0029028584 scopus 로고
    • Evidence for a NIMA-like mitotic pathway in vertebrate cells
    • Lu KP, Hunter T. Evidence for a NIMA-like mitotic pathway in vertebrate cells. Cell 1995; 81:413-24.
    • (1995) Cell , vol.81 , pp. 413-424
    • Lu, K.P.1    Hunter, T.2
  • 33
    • 0028080102 scopus 로고
    • Premature chromatin condensation upon accumulation of NIMA
    • O'Connell MJ, Norbury C, Nurse P. Premature chromatin condensation upon accumulation of NIMA. EMBO J 1994; 13:4926-37.
    • (1994) EMBO J , vol.13 , pp. 4926-4937
    • O'Connell, M.J.1    Norbury, C.2    Nurse, P.3
  • 34
    • 0028910163 scopus 로고
    • Mitotic destruction of the cell cycle regulated NIMA protein kinase of Aspergillus nidulans is required for mitotic exit
    • Pu RT, Osmani SA. Mitotic destruction of the cell cycle regulated NIMA protein kinase of Aspergillus nidulans is required for mitotic exit. EMBO J 1995; 14:995-1003.
    • (1995) EMBO J , vol.14 , pp. 995-1003
    • Pu, R.T.1    Osmani, S.A.2
  • 35
    • 0037365789 scopus 로고    scopus 로고
    • ATM and related protein kinases: Safeguarding genome integrity
    • Shiloh Y. ATM and related protein kinases: safeguarding genome integrity. Nat Rev Cancer 2003; 3:155-68.
    • (2003) Nat Rev Cancer , vol.3 , pp. 155-168
    • Shiloh, Y.1
  • 36
    • 54049097013 scopus 로고    scopus 로고
    • Expression of Nek1 protein kinase during kidney development and after ischemic tubular injury (Abstract)
    • Riley DJ, Achinger SG, Chen Y. Expression of Nek1 protein kinase during kidney development and after ischemic tubular injury (Abstract). J Am Soc Nephrol 2003; 14:366.
    • (2003) J Am Soc Nephrol , vol.14 , pp. 366
    • Riley, D.J.1    Achinger, S.G.2    Chen, Y.3
  • 37
    • 33745823159 scopus 로고    scopus 로고
    • The ATM-mediated DNA-damage response: Taking shape
    • Shiloh Y. The ATM-mediated DNA-damage response: taking shape. Trends Biochem Sci 2006; 31:402-10.
    • (2006) Trends Biochem Sci , vol.31 , pp. 402-410
    • Shiloh, Y.1
  • 38
    • 3242891189 scopus 로고    scopus 로고
    • The Mre11 complex and the metabolism of chromosome breaks: The importance of communicating and holding things together
    • Stracker TH, Theunissen JW, Morales M, Petrini JH. The Mre11 complex and the metabolism of chromosome breaks: the importance of communicating and holding things together. DNA Repair (Amst) 2004; 3:845-54.
    • (2004) DNA Repair (Amst) , vol.3 , pp. 845-854
    • Stracker, T.H.1    Theunissen, J.W.2    Morales, M.3    Petrini, J.H.4
  • 39
    • 0346963147 scopus 로고    scopus 로고
    • Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1
    • Surpili MJ, Delben TM, Kobarg J. Identification of proteins that interact with the central coiled-coil region of the human protein kinase NEK1. Biochemistry 2003; 42:15369-76.
    • (2003) Biochemistry , vol.42 , pp. 15369-15376
    • Surpili, M.J.1    Delben, T.M.2    Kobarg, J.3
  • 41
    • 0028114564 scopus 로고
    • The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing
    • Durfee T, Mancini MA, Jones D, Elledge SJ, Lee WH. The amino-terminal region of the retinoblastoma gene product binds a novel nuclear matrix protein that co-localizes to centers for RNA processing. J Cell Biol 1994; 127:609-22.
    • (1994) J Cell Biol , vol.127 , pp. 609-622
    • Durfee, T.1    Mancini, M.A.2    Jones, D.3    Elledge, S.J.4    Lee, W.H.5
  • 42
    • 0038391226 scopus 로고    scopus 로고
    • NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage
    • Peng A, Chen PL. NFBD1, like 53BP1, is an early and redundant transducer mediating Chk2 phosphorylation in response to DNA damage. J Biol Chem 2003; 278:8873-6.
    • (2003) J Biol Chem , vol.278 , pp. 8873-8876
    • Peng, A.1    Chen, P.L.2


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.