Defective Mre11-dependent activation of Chk2 by ataxia telangiectasia mutated in colorectal carcinoma cells in response to replication-dependent DNA double strand breaks

Journal of Biological Chemistry

Volumn 281, Issue 41, 2006, Pages 30814-30823

  Takemura, Haruyuki ^a   Rao, V Ashutosh ^a   Sordet, Olivier ^a   Furuta, Takahisa ^a   Miao, Ze Hong ^a   Meng, LingHua ^a   Zhang, Hongliang ^a   Pommier, Yves ^a  

^a NATIONAL INSTITUTES OF HEALTH   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CAMPTOTHECIN; CARCINOMA CELL LINES; COLORECTAL CANCERS; GENOMIC INSTABILITY;

BIOCHEMISTRY; DNA; DRUG PRODUCTS; ENZYME KINETICS; RNA;

CELLS;

CAMPTOTHECIN; CHECKPOINT KINASE 2; DNA TOPOISOMERASE; MRE11 PROTEIN; NIBRIN; RAD50 PROTEIN; SMALL INTERFERING RNA;

ARTICLE; ATAXIA TELANGIECTASIA; CARCINOMA CELL; CELL CYCLE G2 PHASE; CELL LINE; COLORECTAL CANCER; CONTROLLED STUDY; DNA REPLICATION; DNA STRAND BREAKAGE; DOWN REGULATION; GENE MUTATION; HUMAN; HUMAN CELL; PRIORITY JOURNAL;

CARCINOMA; CELL CYCLE PROTEINS; CELL LINE, TUMOR; COLORECTAL NEOPLASMS; DNA DAMAGE; DNA REPAIR; DNA REPLICATION; DNA, COMPLEMENTARY; DNA-BINDING PROTEINS; DRUG SCREENING ASSAYS, ANTITUMOR; GENE EXPRESSION REGULATION, NEOPLASTIC; HUMANS; MODELS, BIOLOGICAL; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; TUMOR SUPPRESSOR PROTEINS;

ATAXIA TELANGIECTASIA;

EID: 33749028012     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M603747200     Document Type: Article

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