Phosphorylation of CLK2 at serine 34 and threonine 127 by AKT controls cell survival after ionizing radiation

Journal of Biological Chemistry

Volumn 285, Issue 41, 2010, Pages 31157-31163

  Nam, Seon Young ^a   Seo, Hyung Ho ^a   Park, Hyung Sun ^a   An, Sungkwan ^b   Kim, Ji Young ^a   Yang, Kwang Hee ^a   Kim, Cha Soon ^a   Jeong, Meeseon ^a   Jin, Young Woo ^a  

^a Korea Hydro & Nuclear Power Co   (South Korea)

^b Konkuk University   (South Korea)

Author keywords

[No Author keywords available]

Indexed keywords

ACTIVATION ANALYSIS; CELL DEATH; GROWTH KINETICS; IONIZING RADIATION; MACHINERY; PHOSPHORYLATION; RADIATION SHIELDING; RADIOACTIVITY;

AKT ACTIVATION; CELL SURVIVAL; HELA CELL; IN-CELL; IN-VITRO; OVER-EXPRESSION; REGULATORY MECHANISM;

AMINO ACIDS;

CYCLIN DEPENDENT KINASE 1; INSULIN; MYC PROTEIN; PROTEIN KINASE B; SERINE; SMALL INTERFERING RNA; THREONINE; ANTIDIABETIC AGENT; CLK DUAL-SPECIFICITY KINASES; PROTEIN SERINE THREONINE KINASE; PROTEIN TYROSINE KINASE;

ARTICLE; CELL DEATH; CELL GROWTH; CELL SURVIVAL; CELL VIABILITY; CONTROLLED STUDY; ENZYME ACTIVATION; ENZYME ACTIVITY; ENZYME ANALYSIS; ENZYME BINDING; ENZYME PHOSPHORYLATION; ENZYME REPRESSION; ENZYME SUBSTRATE; GAMMA RADIATION; GENE OVEREXPRESSION; HELA CELL; HUMAN; HUMAN CELL; IN VITRO STUDY; IN VIVO STUDY; IONIZING RADIATION; PRIORITY JOURNAL; PROTEIN EXPRESSION; PROTEIN FUNCTION; PROTEIN PROTEIN INTERACTION; DRUG EFFECTS; GENE SILENCING; GENETICS; HELA CELL LINE; METABOLISM; PHOSPHORYLATION; RADIATION RESPONSE;

CELL DEATH; CELL SURVIVAL; ENZYME ACTIVATION; GAMMA RAYS; GENE SILENCING; HELA CELLS; HUMANS; HYPOGLYCEMIC AGENTS; INSULIN; PHOSPHORYLATION; PROTEIN-SERINE-THREONINE KINASES; PROTEIN-TYROSINE KINASES; PROTO-ONCOGENE PROTEINS C-AKT; RNA, SMALL INTERFERING;

EID: 77957767703     PISSN: 00219258     EISSN: 1083351X     Source Type: Journal    
DOI: 10.1074/jbc.M110.122044     Document Type: Article

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