-
1
-
-
0034733635
-
A novel mammalian iron-regulated protein involved in intracellular iron metabolism
-
Abboud S and Haile DJ. A novel mammalian iron-regulated protein involved in intracellular iron metabolism. J Biol Chem 275: 19906-19912, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 19906-19912
-
-
Abboud, S.1
Haile, D.J.2
-
2
-
-
0033838364
-
Iron-dependent self-assembly of recombinant yeast frataxin: Implications for Friedreich ataxia
-
Adamec J, Rusnak F, Owen WG, Naylor S, Benson LM, Gacy AM, and Isaya G. Iron-dependent self-assembly of recombinant yeast frataxin: implications for Friedreich ataxia. Am J Hum Genet 67: 549-562, 2000.
-
(2000)
Am J Hum Genet
, vol.67
, pp. 549-562
-
-
Adamec, J.1
Rusnak, F.2
Owen, W.G.3
Naylor, S.4
Benson, L.M.5
Gacy, A.M.6
Isaya, G.7
-
3
-
-
0023813241
-
Isolation of a human hepatic ferritin receptor
-
Adams PC, Powell LW, and Halliday JW. Isolation of a human hepatic ferritin receptor. Hepatology 8: 719-721, 1988.
-
(1988)
Hepatology
, vol.8
, pp. 719-721
-
-
Adams, P.C.1
Powell, L.W.2
Halliday, J.W.3
-
4
-
-
0017885589
-
Stoichiometric and site characteristics of the binding of iron to human transferrin
-
Aisen P, Leibman A, and Zweier J. Stoichiometric and site characteristics of the binding of iron to human transferrin. J Biol Chem 253: 1930-1937, 1978.
-
(1978)
J Biol Chem
, vol.253
, pp. 1930-1937
-
-
Aisen, P.1
Leibman, A.2
Zweier, J.3
-
5
-
-
33749638768
-
GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology
-
Al-Mahdawi S, Pinto RM, Varshney D, Lawrence L, Lowrie MB, Hughes S, Webster Z, Blake J, Cooper JM, King R, and Pook MA. GAA repeat expansion mutation mouse models of Friedreich ataxia exhibit oxidative stress leading to progressive neuronal and cardiac pathology. Genomics 88: 580-590, 2006.
-
(2006)
Genomics
, vol.88
, pp. 580-590
-
-
Al-Mahdawi, S.1
Pinto, R.M.2
Varshney, D.3
Lawrence, L.4
Lowrie, M.B.5
Hughes, S.6
Webster, Z.7
Blake, J.8
Cooper, J.M.9
King, R.10
Pook, M.A.11
-
6
-
-
0029019008
-
Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer
-
Alam J, Camhi S, and Choi AM. Identification of a second region upstream of the mouse heme oxygenase-1 gene that functions as a basal level and inducer-dependent transcription enhancer. J Biol Chem 270: 11977-11984, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 11977-11984
-
-
Alam, J.1
Camhi, S.2
Choi, A.M.3
-
7
-
-
0024326182
-
Identification of H- and L-ferritin subunit binding sites on human T and B lymphoid cells
-
Anderson GJ, Faulk WP, Arosio P, Moss D, Powell LW, and Halliday JW. Identification of H- and L-ferritin subunit binding sites on human T and B lymphoid cells. Br J Haematol 73: 260-264, 1989.
-
(1989)
Br J Haematol
, vol.73
, pp. 260-264
-
-
Anderson, G.J.1
Faulk, W.P.2
Arosio, P.3
Moss, D.4
Powell, L.W.5
Halliday, J.W.6
-
8
-
-
34547125378
-
Sustained hydrogen peroxide induces iron uptake by transferrin receptor-1 independent of the iron regulatory protein/iron- responsive element network
-
Andriopoulos B, Hegedusch S, Mangin J, Riedel HD, Hebling U, Wang J, Pantopoulos K, and Mueller S. Sustained hydrogen peroxide induces iron uptake by transferrin receptor-1 independent of the iron regulatory protein/iron- responsive element network. J Biol Chem 282: 20301-20308, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 20301-20308
-
-
Andriopoulos, B.1
Hegedusch, S.2
Mangin, J.3
Riedel, H.D.4
Hebling, U.5
Wang, J.6
Pantopoulos, K.7
Mueller, S.8
-
9
-
-
0037101879
-
Ferritin, iron homeostasis, and oxidative damage
-
Arosio P and Levi S. Ferritin, iron homeostasis, and oxidative damage. Free Radic Biol Med 33: 457-463, 2002.
-
(2002)
Free Radic Biol Med
, vol.33
, pp. 457-463
-
-
Arosio, P.1
Levi, S.2
-
10
-
-
0017182231
-
Structural and immunological relationships of isoferritins in normal and malignant cells
-
Arosio P, Yokota M, and Drysdale JW. Structural and immunological relationships of isoferritins in normal and malignant cells. Cancer Res 36: 1735-1739, 1976.
-
(1976)
Cancer Res
, vol.36
, pp. 1735-1739
-
-
Arosio, P.1
Yokota, M.2
Drysdale, J.W.3
-
11
-
-
0030774203
-
High serum ferritin concentration in an AIDS patient with miliary tuberculosis
-
Arranz Caso JA, Garcia Tena J, Llorens MM, and Moreno R. High serum ferritin concentration in an AIDS patient with miliary tuberculosis. Clin Infect Dis 25: 1263-1264, 1997.
-
(1997)
Clin Infect Dis
, vol.25
, pp. 1263-1264
-
-
Arranz Caso, J.A.1
Garcia Tena, J.2
Llorens, M.M.3
Moreno, R.4
-
12
-
-
0028058038
-
The FET3 gene of S cerevisiae encodes a multicopper oxidase required for ferrous iron uptake
-
Askwith C, Eide D, Van Ho A, Bernard PS, Li L, Davis-Kaplan S, Sipe DM, and Kaplan J. The FET3 gene of S cerevisiae encodes a multicopper oxidase required for ferrous iron uptake. Cell 76: 403-410, 1994.
-
(1994)
Cell
, vol.76
, pp. 403-410
-
-
Askwith, C.1
Eide, D.2
Van Ho, A.3
Bernard, P.S.4
Li, L.5
Davis-Kaplan, S.6
Sipe, D.M.7
Kaplan, J.8
-
13
-
-
0030846021
-
Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin
-
Babcock M, de Silva D, Oaks R, Davis-Kaplan S, Jiralerspong S, Montermini L, Pandolfo M, and Kaplan J. Regulation of mitochondrial iron accumulation by Yfh1p, a putative homolog of frataxin. Science 276: 1709-1712, 1997.
-
(1997)
Science
, vol.276
, pp. 1709-1712
-
-
Babcock, M.1
de Silva, D.2
Oaks, R.3
Davis-Kaplan, S.4
Jiralerspong, S.5
Montermini, L.6
Pandolfo, M.7
Kaplan, J.8
-
14
-
-
33646370235
-
Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression
-
Babitt JL, Huang FW, Wrighting DM, Xia Y, Sidis Y, Samad TA, Campagna JA, Chung RT, Schneyer AL, Woolf CJ, Andrews NC, and Lin HY. Bone morphogenetic protein signaling by hemojuvelin regulates hepcidin expression. Nat Genet 38: 531-539, 2006.
-
(2006)
Nat Genet
, vol.38
, pp. 531-539
-
-
Babitt, J.L.1
Huang, F.W.2
Wrighting, D.M.3
Xia, Y.4
Sidis, Y.5
Samad, T.A.6
Campagna, J.A.7
Chung, R.T.8
Schneyer, A.L.9
Woolf, C.J.10
Andrews, N.C.11
Lin, H.Y.12
-
15
-
-
34447137331
-
Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance
-
Babitt JL, Huang FW, Xia Y, Sidis Y, Andrews NC, and Lin HY. Modulation of bone morphogenetic protein signaling in vivo regulates systemic iron balance. J Clin Invest 117: 1933-1939, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 1933-1939
-
-
Babitt, J.L.1
Huang, F.W.2
Xia, Y.3
Sidis, Y.4
Andrews, N.C.5
Lin, H.Y.6
-
16
-
-
0029953753
-
Hemochromatosis: The genetic disorder of the twenty-first century
-
Barton JC and Bertoli LF. Hemochromatosis: the genetic disorder of the twenty-first century. Nat Med 2: 394-395, 1996.
-
(1996)
Nat Med
, vol.2
, pp. 394-395
-
-
Barton, J.C.1
Bertoli, L.F.2
-
17
-
-
0025941184
-
Intracellular heme coordinately modulates globin chain synthesis, transferrin receptor number, and ferritin content in differentiating Friend erythroleukemia cells
-
Battistini A, Coccia EM, Marziali G, Bulgarini D, Scalzo S, Fiorucci G, Romeo G, Affabris E, Testa U, Rossi GB, and Peschle C. Intracellular heme coordinately modulates globin chain synthesis, transferrin receptor number, and ferritin content in differentiating Friend erythroleukemia cells. Blood 78: 2098-2103, 1991.
-
(1991)
Blood
, vol.78
, pp. 2098-2103
-
-
Battistini, A.1
Coccia, E.M.2
Marziali, G.3
Bulgarini, D.4
Scalzo, S.5
Fiorucci, G.6
Romeo, G.7
Affabris, E.8
Testa, U.9
Rossi, G.B.10
Peschle, C.11
-
18
-
-
0038670759
-
Iron deficiency alters brain development and functioning
-
Beard J. Iron deficiency alters brain development and functioning. J Nutr 133: 1468S-1472S, 2003.
-
(2003)
J Nutr
, vol.133
-
-
Beard, J.1
-
19
-
-
0028881134
-
Mutation in the iron responsive element of the L ferritin mRNA in a family with dominant hyperferritinaemia and cataract
-
Beaumont C, Leneuve P, Devaux I, Scoazec JY, Berthier M, Loiseau MN, Grandchamp B, and Bonneau D. Mutation in the iron responsive element of the L ferritin mRNA in a family with dominant hyperferritinaemia and cataract. Nat Genet 11: 444-446, 1995.
-
(1995)
Nat Genet
, vol.11
, pp. 444-446
-
-
Beaumont, C.1
Leneuve, P.2
Devaux, I.3
Scoazec, J.Y.4
Berthier, M.5
Loiseau, M.N.6
Grandchamp, B.7
Bonneau, D.8
-
20
-
-
0027938713
-
Mouse ferritin H subunit gene: Functional analysis of the promoter and identification of an upstream regulatory element active in erythroid cells
-
Beaumont C, Seyhan A, Yachou AK, Grandchamp B, and Jones R. Mouse ferritin H subunit gene: functional analysis of the promoter and identification of an upstream regulatory element active in erythroid cells. J Biol Chem 269: 20281-20288, 1994.
-
(1994)
J Biol Chem
, vol.269
, pp. 20281-20288
-
-
Beaumont, C.1
Seyhan, A.2
Yachou, A.K.3
Grandchamp, B.4
Jones, R.5
-
22
-
-
0033230181
-
HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation
-
Bianchi L, Tacchini L, and Cairo G. HIF-1-mediated activation of transferrin receptor gene transcription by iron chelation. Nucleic Acids Res 27: 4223-4227, 1999.
-
(1999)
Nucleic Acids Res
, vol.27
, pp. 4223-4227
-
-
Bianchi, L.1
Tacchini, L.2
Cairo, G.3
-
23
-
-
0031941447
-
The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure
-
Bidichandani SI, Ashizawa T, and Patel PI. The GAA triplet-repeat expansion in Friedreich ataxia interferes with transcription and may be associated with an unusual DNA structure. Am J Hum Genet 62: 111-121, 1998.
-
(1998)
Am J Hum Genet
, vol.62
, pp. 111-121
-
-
Bidichandani, S.I.1
Ashizawa, T.2
Patel, P.I.3
-
24
-
-
0036970184
-
Iron: A pathological mediator of Alzheimer disease?
-
Bishop GM, Robinson SR, Liu Q, Perry G, Atwood CS, and Smith MA. Iron: a pathological mediator of Alzheimer disease? Dev Neurosci 24: 184-187, 2002.
-
(2002)
Dev Neurosci
, vol.24
, pp. 184-187
-
-
Bishop, G.M.1
Robinson, S.R.2
Liu, Q.3
Perry, G.4
Atwood, C.S.5
Smith, M.A.6
-
25
-
-
0025324091
-
Structure, function, and diversity of class I major histocompatibility complex molecules
-
Bjorkman PJ and Parham P. Structure, function, and diversity of class I major histocompatibility complex molecules. Annu Rev Biochem 59: 253-288, 1990.
-
(1990)
Annu Rev Biochem
, vol.59
, pp. 253-288
-
-
Bjorkman, P.J.1
Parham, P.2
-
26
-
-
34347370842
-
Selective iron chelation in Friedreich ataxia: Biologic and clinical implications
-
Boddaert N, Le Quan Sang KH, Rotig A, Leroy-Willig A, Gallet S, Brunelle F, Sidi D, Thalabard JC, Munnich A, and Cabantchik ZI. Selective iron chelation in Friedreich ataxia: biologic and clinical implications. Blood 110: 401-408, 2007.
-
(2007)
Blood
, vol.110
, pp. 401-408
-
-
Boddaert, N.1
Le Quan Sang, K.H.2
Rotig, A.3
Leroy-Willig, A.4
Gallet, S.5
Brunelle, F.6
Sidi, D.7
Thalabard, J.C.8
Munnich, A.9
Cabantchik, Z.I.10
-
27
-
-
34447523329
-
Regulation of pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors
-
Boutet SC, Disatnik MH, Chan LS, Iori K, and Rando TA. Regulation of pax3 by proteasomal degradation of monoubiquitinated protein in skeletal muscle progenitors. Cell 130: 349-362, 2007.
-
(2007)
Cell
, vol.130
, pp. 349-362
-
-
Boutet, S.C.1
Disatnik, M.H.2
Chan, L.S.3
Iori, K.4
Rando, T.A.5
-
28
-
-
0033957174
-
Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia
-
Bradley JL, Blake JC, Chamberlain S, Thomas PK, Cooper JM, and Schapira AH. Clinical, biochemical and molecular genetic correlations in Friedreich's ataxia. Hum Mol Genet 9: 275-282, 2000
-
(2000)
Hum Mol Genet
, vol.9
, pp. 275-282
-
-
Bradley, J.L.1
Blake, J.C.2
Chamberlain, S.3
Thomas, P.K.4
Cooper, J.M.5
Schapira, A.H.6
-
29
-
-
0033529554
-
Yeast and human frataxin are processed to mature form in two sequential steps by the mitochondrial processing peptidase
-
Branda SS, Cavadini P, Adamec J, Kalousek F, Taroni F, and Isaya G. Yeast and human frataxin are processed to mature form in two sequential steps by the mitochondrial processing peptidase. J Biol Chem 274: 22763-22769, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 22763-22769
-
-
Branda, S.S.1
Cavadini, P.2
Adamec, J.3
Kalousek, F.4
Taroni, F.5
Isaya, G.6
-
30
-
-
3042763187
-
Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity
-
Bulteau AL, O'Neill HA, Kennedy MC, Ikeda-Saito M, Isaya G, and Szweda LI. Frataxin acts as an iron chaperone protein to modulate mitochondrial aconitase activity. Science 305: 242-245, 2004.
-
(2004)
Science
, vol.305
, pp. 242-245
-
-
Bulteau, A.L.1
O'Neill, H.A.2
Kennedy, M.C.3
Ikeda-Saito, M.4
Isaya, G.5
Szweda, L.I.6
-
31
-
-
33746795976
-
DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia
-
Burnett R, Melander C, Puckett JW, Son LS, Wells RD, Dervan PB, and Gottesfeld JM. DNA sequence-specific polyamides alleviate transcription inhibition associated with long GAA.TTC repeats in Friedreich's ataxia. Proc Natl Acad Sci U S A 103: 11497-11502, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 11497-11502
-
-
Burnett, R.1
Melander, C.2
Puckett, J.W.3
Son, L.S.4
Wells, R.D.5
Dervan, P.B.6
Gottesfeld, J.M.7
-
32
-
-
0030992780
-
Ferritin is a developmentally regulated nuclear protein of avian corneal epithelial cells
-
Cai CX, Birk DE, and Linsenmayer TF. Ferritin is a developmentally regulated nuclear protein of avian corneal epithelial cells. J Biol Chem 272: 12831-12839, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 12831-12839
-
-
Cai, C.X.1
Birk, D.E.2
Linsenmayer, T.F.3
-
33
-
-
0031670727
-
Nuclear ferritin protects DNA from UV damage in corneal epithelial cells
-
Cai CX, Birk DE, and Linsenmayer TF. Nuclear ferritin protects DNA from UV damage in corneal epithelial cells. Mol Biol Cell 9: 1037-1051, 1998.
-
(1998)
Mol Biol Cell
, vol.9
, pp. 1037-1051
-
-
Cai, C.X.1
Birk, D.E.2
Linsenmayer, T.F.3
-
34
-
-
0035827697
-
Modulation of cellular iron metabolism by hydrogen peroxide: Effects of H2O2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts
-
Caltagirone A, Weiss G, and Pantopoulos K. Modulation of cellular iron metabolism by hydrogen peroxide: effects of H2O2 on the expression and function of iron-responsive element-containing mRNAs in B6 fibroblasts. J Biol Chem 276: 19738-19745, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 19738-19745
-
-
Caltagirone, A.1
Weiss, G.2
Pantopoulos, K.3
-
35
-
-
0034022636
-
The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22
-
Camaschella C, Roetto A, Cali A, De Gobbi M, Garozzo G, Carella M, Majorano N, Totaro A, and Gasparini P. The gene TFR2 is mutated in a new type of haemochromatosis mapping to 7q22. Nat Genet 25: 14-15, 2000.
-
(2000)
Nat Genet
, vol.25
, pp. 14-15
-
-
Camaschella, C.1
Roetto, A.2
Cali, A.3
De Gobbi, M.4
Garozzo, G.5
Carella, M.6
Majorano, N.7
Totaro, A.8
Gasparini, P.9
-
36
-
-
0036431779
-
Genetic haemochromatosis: Genes and mutations associated with iron loading
-
Camaschella C, Roetto A, and De Gobbi M. Genetic haemochromatosis: genes and mutations associated with iron loading. Best Pract Res Clin Haematol 15: 261-276, 2002.
-
(2002)
Best Pract Res Clin Haematol
, vol.15
, pp. 261-276
-
-
Camaschella, C.1
Roetto, A.2
De Gobbi, M.3
-
37
-
-
5444262935
-
The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast
-
Campanella A, Isaya G, O'Neill HA, Santambrogio P, Cozzi A, Arosio P, and Levi S. The expression of human mitochondrial ferritin rescues respiratory function in frataxin-deficient yeast. Hum Mol Genet 13: 2279-2288, 2004.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 2279-2288
-
-
Campanella, A.1
Isaya, G.2
O'Neill, H.A.3
Santambrogio, P.4
Cozzi, A.5
Arosio, P.6
Levi, S.7
-
38
-
-
13344270899
-
Friedreich's ataxia: Autosomal recessive disease caused by an intronic GAA triplet repeat expansion
-
Campuzano V, Montermini L, Molto MD, Pianese L, Cossee M, Cavalcanti F, Monros E, Rodius F, Duclos F, Monticelli A, Zara F, Canizares J, Koutnikova H, Bidichandani SI, Gellera C, Brice A, Trouillas P, De Michele G, Filla A, De Frutos R, Palau F, Patel PI, Di Donato S, Mandel JL, Cocozza S, Koenig M, and Pandolfo M. Friedreich's ataxia: autosomal recessive disease caused by an intronic GAA triplet repeat expansion. Science 271: 1423-1427, 1996.
-
(1996)
Science
, vol.271
, pp. 1423-1427
-
-
Campuzano, V.1
Montermini, L.2
Molto, M.D.3
Pianese, L.4
Cossee, M.5
Cavalcanti, F.6
Monros, E.7
Rodius, F.8
Duclos, F.9
Monticelli, A.10
Zara, F.11
Canizares, J.12
Koutnikova, H.13
Bidichandani, S.I.14
Gellera, C.15
Brice, A.16
Trouillas, P.17
De Michele, G.18
Filla, A.19
De Frutos, R.20
Palau, F.21
Patel, P.I.22
Di Donato, S.23
Mandel, J.L.24
Cocozza, S.25
Koenig, M.26
Pandolfo, M.27
more..
-
39
-
-
0033564656
-
Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron
-
Canonne-Hergaux F, Gruenheid S, Ponka P, and Gros P. Cellular and subcellular localization of the Nramp2 iron transporter in the intestinal brush border and regulation by dietary iron. Blood 93: 4406-4417, 1999.
-
(1999)
Blood
, vol.93
, pp. 4406-4417
-
-
Canonne-Hergaux, F.1
Gruenheid, S.2
Ponka, P.3
Gros, P.4
-
40
-
-
0035895096
-
Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice
-
Canonne-Hergaux F, Zhang AS, Ponka P, and Gros P. Characterization of the iron transporter DMT1 (NRAMP2/DCT1) in red blood cells of normal and anemic mk/mk mice. Blood 98: 3823-3830, 2001.
-
(2001)
Blood
, vol.98
, pp. 3823-3830
-
-
Canonne-Hergaux, F.1
Zhang, A.S.2
Ponka, P.3
Gros, P.4
-
41
-
-
16944363480
-
Mutation analysis of the HLA-H gene in Italian hemochromatosis patients
-
Carella M, D'Ambrosio L, Totaro A, Grifa A, Valentino MA, Piperno A, Girelli D, Roetto A, Franco B, Gasparini P, and Camaschella C. Mutation analysis of the HLA-H gene in Italian hemochromatosis patients. Am J Hum Genet 60: 828-832, 1997.
-
(1997)
Am J Hum Genet
, vol.60
, pp. 828-832
-
-
Carella, M.1
D'Ambrosio, L.2
Totaro, A.3
Grifa, A.4
Valentino, M.A.5
Piperno, A.6
Girelli, D.7
Roetto, A.8
Franco, B.9
Gasparini, P.10
Camaschella, C.11
-
42
-
-
0023882711
-
Iron-responsive elements: Regulatory RNA sequences that control mRNA levels and translation
-
Casey JL, Hentze MW, Koeller DM, Caughman SW, Rouault TA, Klausner RD, and Harford JB. Iron-responsive elements: regulatory RNA sequences that control mRNA levels and translation. Science 240: 924-928, 1988.
-
(1988)
Science
, vol.240
, pp. 924-928
-
-
Casey, J.L.1
Hentze, M.W.2
Koeller, D.M.3
Caughman, S.W.4
Rouault, T.A.5
Klausner, R.D.6
Harford, J.B.7
-
43
-
-
33845387875
-
Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeys
-
Cass WA, Grondin R, Andersen AH, Zhang Z, Hardy PA, Hussey-Andersen LK, Rayens WS, Gerhardt GA, and Gash DM. Iron accumulation in the striatum predicts aging-related decline in motor function in rhesus monkeys. Neurobiol Aging 28: 258-271, 2007.
-
(2007)
Neurobiol Aging
, vol.28
, pp. 258-271
-
-
Cass, W.A.1
Grondin, R.2
Andersen, A.H.3
Zhang, Z.4
Hardy, P.A.5
Hussey-Andersen, L.K.6
Rayens, W.S.7
Gerhardt, G.A.8
Gash, D.M.9
-
44
-
-
0034731447
-
Two-step processing of human frataxin by mitochondrial processing peptidase: Precursor and intermediate forms are cleaved at different rates
-
Cavadini P, Adamec J, Taroni F, Gakh O, and Isaya G. Two-step processing of human frataxin by mitochondrial processing peptidase: precursor and intermediate forms are cleaved at different rates. J Biol Chem 275: 41469-41475, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 41469-41475
-
-
Cavadini, P.1
Adamec, J.2
Taroni, F.3
Gakh, O.4
Isaya, G.5
-
45
-
-
0036472291
-
Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia
-
Cavadini P, O'Neill HA, Benada O, and Isaya G. Assembly and iron-binding properties of human frataxin, the protein deficient in Friedreich ataxia. Hum Mol Genet 11: 217-227, 2002.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 217-227
-
-
Cavadini, P.1
O'Neill, H.A.2
Benada, O.3
Isaya, G.4
-
46
-
-
0030451213
-
NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development
-
Chan K, Lu R, Chang JC, and Kan YW. NRF2, a member of the NFE2 family of transcription factors, is not essential for murine erythropoiesis, growth, and development. Proc Natl Acad Sci U S A 93: 13943-13948, 1996.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 13943-13948
-
-
Chan, K.1
Lu, R.2
Chang, J.C.3
Kan, Y.W.4
-
47
-
-
0034778392
-
Disabled early recruitment of antioxidant defenses in Friedreich's ataxia
-
Chantrel-Groussard K, Geromel V, Puccio H, Koenig M, Munnich A, Rotig A, and Rustin P. Disabled early recruitment of antioxidant defenses in Friedreich's ataxia. Hum Mol Genet 10: 2061-2067, 2001.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2061-2067
-
-
Chantrel-Groussard, K.1
Geromel, V.2
Puccio, H.3
Koenig, M.4
Munnich, A.5
Rotig, A.6
Rustin, P.7
-
48
-
-
0037126057
-
Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: Evidence that Yfh1p affects Fe-S cluster synthesis
-
Chen OS, Hemenway S, and Kaplan J. Inhibition of Fe-S cluster biosynthesis decreases mitochondrial iron export: evidence that Yfh1p affects Fe-S cluster synthesis. Proc Natl Acad Sci U S A 99: 12321-12326, 2002.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12321-12326
-
-
Chen, O.S.1
Hemenway, S.2
Kaplan, J.3
-
49
-
-
25844475970
-
TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis
-
Chen TT, Li L, Chung DH, Allen CD, Torti SV, Torti FM, Cyster JG, Chen CY, Brodsky FM, Niemi EC, Nakamura MC, Seaman WE, and Daws MR. TIM-2 is expressed on B cells and in liver and kidney and is a receptor for H-ferritin endocytosis. J Exp Med 202: 955-965, 2005.
-
(2005)
J Exp Med
, vol.202
, pp. 955-965
-
-
Chen, T.T.1
Li, L.2
Chung, D.H.3
Allen, C.D.4
Torti, S.V.5
Torti, F.M.6
Cyster, J.G.7
Chen, C.Y.8
Brodsky, F.M.9
Niemi, E.C.10
Nakamura, M.C.11
Seaman, W.E.12
Daws, M.R.13
-
50
-
-
1342264310
-
Structure of the human transferrin receptor-transferrin complex
-
Cheng Y, Zak O, Aisen P, Harrison SC, and Walz T. Structure of the human transferrin receptor-transferrin complex. Cell 116: 565-576, 2004.
-
(2004)
Cell
, vol.116
, pp. 565-576
-
-
Cheng, Y.1
Zak, O.2
Aisen, P.3
Harrison, S.C.4
Walz, T.5
-
51
-
-
33845899114
-
Clinical features and natural history of neuroferritinopathy caused by the FTL1 460InsA mutation
-
Chinnery PF, Crompton DE, Birchall D, Jackson MJ, Coulthard A, Lombes A, Quinn N, Wills A, Fletcher N, Mottershead JP, Cooper P, Kellett M, Bates D, and Burn J. Clinical features and natural history of neuroferritinopathy caused by the FTL1 460InsA mutation. Brain 130: 110-119, 2007.
-
(2007)
Brain
, vol.130
, pp. 110-119
-
-
Chinnery, P.F.1
Crompton, D.E.2
Birchall, D.3
Jackson, M.J.4
Coulthard, A.5
Lombes, A.6
Quinn, N.7
Wills, A.8
Fletcher, N.9
Mottershead, J.P.10
Cooper, P.11
Kellett, M.12
Bates, D.13
Burn, J.14
-
52
-
-
0025635559
-
Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis
-
Collawn JF, Stangel M, Kuhn LA, Esekogwu V, Jing SQ, Trowbridge IS, and Tainer JA. Transferrin receptor internalization sequence YXRF implicates a tight turn as the structural recognition motif for endocytosis. Cell 63: 1061-1072, 1990.
-
(1990)
Cell
, vol.63
, pp. 1061-1072
-
-
Collawn, J.F.1
Stangel, M.2
Kuhn, L.A.3
Esekogwu, V.4
Jing, S.Q.5
Trowbridge, I.S.6
Tainer, J.A.7
-
53
-
-
34447318623
-
In vivo maturation of human frataxin
-
Condo I, Ventura N, Malisan F, Rufini A, Tomassini B, and Testi R. In vivo maturation of human frataxin. Hum Mol Genet 16: 1534-1540, 2007.
-
(2007)
Hum Mol Genet
, vol.16
, pp. 1534-1540
-
-
Condo, I.1
Ventura, N.2
Malisan, F.3
Rufini, A.4
Tomassini, B.5
Testi, R.6
-
54
-
-
0028350924
-
Isoforms of ferritin have a specific cellular distribution in the brain
-
Connor JR, Boeshore KL, Benkovic SA, and Menzies SL. Isoforms of ferritin have a specific cellular distribution in the brain. J Neurosci Res 37: 461-465, 1994.
-
(1994)
J Neurosci Res
, vol.37
, pp. 461-465
-
-
Connor, J.R.1
Boeshore, K.L.2
Benkovic, S.A.3
Menzies, S.L.4
-
55
-
-
0027938158
-
Hereditary hemochromatosis: A prevalent disorder of iron metabolism with an elusive etiology
-
Conrad ME, Umbreit JN, Moore EG, and Parmley RT. Hereditary hemochromatosis: a prevalent disorder of iron metabolism with an elusive etiology. Am J Hematol 47: 218-224, 1994.
-
(1994)
Am J Hematol
, vol.47
, pp. 218-224
-
-
Conrad, M.E.1
Umbreit, J.N.2
Moore, E.G.3
Parmley, R.T.4
-
56
-
-
23044503950
-
Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2
-
Cooperman SS, Meyron-Holtz EG, Olivierre-Wilson H, Ghosh MC, McConnell JP, and Rouault TA. Microcytic anemia, erythropoietic protoporphyria, and neurodegeneration in mice with targeted deletion of iron-regulatory protein 2. Blood 106: 1084-1091, 2005.
-
(2005)
Blood
, vol.106
, pp. 1084-1091
-
-
Cooperman, S.S.1
Meyron-Holtz, E.G.2
Olivierre-Wilson, H.3
Ghosh, M.C.4
McConnell, J.P.5
Rouault, T.A.6
-
57
-
-
0037151089
-
Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism
-
Corsi B, Cozzi A, Arosio P, Drysdale J, Santambrogio P, Campanella A, Biasiotto G, Albertini A, and Levi S. Human mitochondrial ferritin expressed in HeLa cells incorporates iron and affects cellular iron metabolism. J Biol Chem 277: 22430-22437, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 22430-22437
-
-
Corsi, B.1
Cozzi, A.2
Arosio, P.3
Drysdale, J.4
Santambrogio, P.5
Campanella, A.6
Biasiotto, G.7
Albertini, A.8
Levi, S.9
-
58
-
-
0034192352
-
Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation
-
Cossee M, Puccio H, Gansmuller A, Koutnikova H, Dierich A, LeMeur M, Fischbeck K, Dolle P, and Koenig M. Inactivation of the Friedreich ataxia mouse gene leads to early embryonic lethality without iron accumulation. Hum Mol Genet 9: 1219-1226, 2000.
-
(2000)
Hum Mol Genet
, vol.9
, pp. 1219-1226
-
-
Cossee, M.1
Puccio, H.2
Gansmuller, A.3
Koutnikova, H.4
Dierich, A.5
LeMeur, M.6
Fischbeck, K.7
Dolle, P.8
Koenig, M.9
-
59
-
-
0037174609
-
C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism: Cross-talk between C/EBP pathway and iron metabolism
-
Courselaud B, Pigeon C, Inoue Y, Inoue J, Gonzalez FJ, Leroyer P, Gilot D, Boudjema K, Guguen-Guillouzo C, Brissot P, Loreal O, and Ilyin G. C/EBPalpha regulates hepatic transcription of hepcidin, an antimicrobial peptide and regulator of iron metabolism: cross-talk between C/EBP pathway and iron metabolism. J Biol Chem 277: 41163-41170, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 41163-41170
-
-
Courselaud, B.1
Pigeon, C.2
Inoue, Y.3
Inoue, J.4
Gonzalez, F.J.5
Leroyer, P.6
Gilot, D.7
Boudjema, K.8
Guguen-Guillouzo, C.9
Brissot, P.10
Loreal, O.11
Ilyin, G.12
-
60
-
-
0034682761
-
Overexpression of wild type and mutated human ferritin Hchain in HeLa cells: In vivo role of ferritin ferroxidase activity
-
Cozzi A, Corsi B, Levi S, Santambrogio P, Albertini A, and Arosio P. Overexpression of wild type and mutated human ferritin Hchain in HeLa cells: in vivo role of ferritin ferroxidase activity. J Biol Chem 275: 25122-25129, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 25122-25129
-
-
Cozzi, A.1
Corsi, B.2
Levi, S.3
Santambrogio, P.4
Albertini, A.5
Arosio, P.6
-
61
-
-
1542373640
-
Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: Evidence for a proliferative role of L-ferritin
-
Cozzi A, Corsi B, Levi S, Santambrogio P, Biasiotto G and Arosio P. Analysis of the biologic functions of H- and L-ferritins in HeLa cells by transfection with siRNAs and cDNAs: evidence for a proliferative role of L-ferritin. Blood 103: 2377-2383, 2004.
-
(2004)
Blood
, vol.103
, pp. 2377-2383
-
-
Cozzi, A.1
Corsi, B.2
Levi, S.3
Santambrogio, P.4
Biasiotto, G.5
Arosio, P.6
-
62
-
-
33747154110
-
Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder
-
Cozzi A, Santambrogio P, Corsi B, Campanella A, Arosio P, and Levi S. Characterization of the l-ferritin variant 460InsA responsible of a hereditary ferritinopathy disorder. Neurobiol Dis 23: 644-652, 2006.
-
(2006)
Neurobiol Dis
, vol.23
, pp. 644-652
-
-
Cozzi, A.1
Santambrogio, P.2
Corsi, B.3
Campanella, A.4
Arosio, P.5
Levi, S.6
-
63
-
-
0034941118
-
Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease
-
Curtis AR, Fey C, Morris CM, Bindoff LA, Ince PG, Chinnery PF, Coulthard A, Jackson MJ, Jackson AP, McHale DP, Hay D, Barker WA, Markham AF, Bates D, Curtis A, and Burn J. Mutation in the gene encoding ferritin light polypeptide causes dominant adult-onset basal ganglia disease. Nat Genet 28: 350-354, 2001.
-
(2001)
Nat Genet
, vol.28
, pp. 350-354
-
-
Curtis, A.R.1
Fey, C.2
Morris, C.M.3
Bindoff, L.A.4
Ince, P.G.5
Chinnery, P.F.6
Coulthard, A.7
Jackson, M.J.8
Jackson, A.P.9
McHale, D.P.10
Hay, D.11
Barker, W.A.12
Markham, A.F.13
Bates, D.14
Curtis, A.15
Burn, J.16
-
64
-
-
0028010889
-
Molecular characterization of a copper transport protein in S. cerevisiae: An unexpected role for copper in iron transport
-
Dancis A, Yuan DS, Haile D, Askwith C, Eide D, Moehle C, Kaplan J, and Klausner RD. Molecular characterization of a copper transport protein in S. cerevisiae: an unexpected role for copper in iron transport. Cell 76: 393-402, 1994.
-
(1994)
Cell
, vol.76
, pp. 393-402
-
-
Dancis, A.1
Yuan, D.S.2
Haile, D.3
Askwith, C.4
Eide, D.5
Moehle, C.6
Kaplan, J.7
Klausner, R.D.8
-
65
-
-
33751103909
-
Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome
-
De Domenico I, Vaughn MB, Li L, Bagley D, Musci G, Ward DM, and Kaplan J. Ferroportin-mediated mobilization of ferritin iron precedes ferritin degradation by the proteasome. EMBO J 25: 5396-5404, 2006.
-
(2006)
EMBO J
, vol.25
, pp. 5396-5404
-
-
De Domenico, I.1
Vaughn, M.B.2
Li, L.3
Bagley, D.4
Musci, G.5
Ward, D.M.6
Kaplan, J.7
-
66
-
-
34250800318
-
Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI-ceruloplasmin
-
De Domenico I, Ward DM, di Patti MC, Jeong SY, David S, Musci G, and Kaplan J. Ferroxidase activity is required for the stability of cell surface ferroportin in cells expressing GPI-ceruloplasmin. EMBO J 26: 2823-2831, 2007.
-
(2007)
EMBO J
, vol.26
, pp. 2823-2831
-
-
De Domenico, I.1
Ward, D.M.2
di Patti, M.C.3
Jeong, S.Y.4
David, S.5
Musci, G.6
Kaplan, J.7
-
67
-
-
34250865977
-
The molecular mechanism of hepcidin-mediated ferroportin down-regulation
-
De Domenico I, Ward DM, Langelier C, Vaughn MB, Nemeth E, Sundquist WI, Ganz T, Musci G, and Kaplan J. The molecular mechanism of hepcidin-mediated ferroportin down-regulation. Mol Biol Cell 18: 2569-2578, 2007.
-
(2007)
Mol Biol Cell
, vol.18
, pp. 2569-2578
-
-
De Domenico, I.1
Ward, D.M.2
Langelier, C.3
Vaughn, M.B.4
Nemeth, E.5
Sundquist, W.I.6
Ganz, T.7
Musci, G.8
Kaplan, J.9
-
68
-
-
32544437693
-
Iron overload due to mutations in ferroportin
-
De Domenico I, Ward DM, Musci G, and Kaplan J. Iron overload due to mutations in ferroportin. Haematologica 91: 92-95, 2006.
-
(2006)
Haematologica
, vol.91
, pp. 92-95
-
-
De Domenico, I.1
Ward, D.M.2
Musci, G.3
Kaplan, J.4
-
69
-
-
21144435281
-
The molecular basis of ferroportin-linked hemochromatosis
-
De Domenico I, Ward DM, Nemeth E, Vaughn MB, Musci G, Ganz T, and Kaplan J. The molecular basis of ferroportin-linked hemochromatosis. Proc Natl Acad Sci U S A 102: 8955-8960, 2005.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 8955-8960
-
-
De Domenico, I.1
Ward, D.M.2
Nemeth, E.3
Vaughn, M.B.4
Musci, G.5
Ganz, T.6
Kaplan, J.7
-
70
-
-
0032914608
-
Direct evidence that mitochondrial iron accumulation occurs in Friedreich ataxia
-
Delatycki MB, Camakaris J, Brooks H, Evans-Whipp T, Thorburn DR, Williamson R, and Forrest SM. Direct evidence that mitochondrial iron accumulation occurs in Friedreich ataxia. Ann Neurol 45: 673-675, 1999.
-
(1999)
Ann Neurol
, vol.45
, pp. 673-675
-
-
Delatycki, M.B.1
Camakaris, J.2
Brooks, H.3
Evans-Whipp, T.4
Thorburn, D.R.5
Williamson, R.6
Forrest, S.M.7
-
71
-
-
2342613613
-
Expression of the human ferritin light chain in a frataxin mutant yeast affects ageing and cell death
-
Desmyter L, Dewaele S, Reekmans R, Nystrom T, Contreras R, and Chen C. Expression of the human ferritin light chain in a frataxin mutant yeast affects ageing and cell death. Exp Gerontol 39: 707-715, 2004.
-
(2004)
Exp Gerontol
, vol.39
, pp. 707-715
-
-
Desmyter, L.1
Dewaele, S.2
Reekmans, R.3
Nystrom, T.4
Contreras, R.5
Chen, C.6
-
72
-
-
0034613233
-
Crystal structure of human frataxin
-
Dhe-Paganon S, Shigeta R, Chi YI, Ristow M, and Shoelson SE. Crystal structure of human frataxin. J Biol Chem 275: 30753-30756, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 30753-30756
-
-
Dhe-Paganon, S.1
Shigeta, R.2
Chi, Y.I.3
Ristow, M.4
Shoelson, S.E.5
-
73
-
-
0034677467
-
Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter
-
Donovan A, Brownlie A, Zhou Y, Shepard J, Pratt SJ, Moynihan J, Paw BH, Drejer A, Barut B, Zapata A, Law TC, Brugnara C, Lux SE, Pinkus GS, Pinkus JL, Kingsley PD, Palis J, Fleming MD, Andrews NC, and Zon LI. Positional cloning of zebrafish ferroportin1 identifies a conserved vertebrate iron exporter. Nature 403: 776-781, 2000.
-
(2000)
Nature
, vol.403
, pp. 776-781
-
-
Donovan, A.1
Brownlie, A.2
Zhou, Y.3
Shepard, J.4
Pratt, S.J.5
Moynihan, J.6
Paw, B.H.7
Drejer, A.8
Barut, B.9
Zapata, A.10
Law, T.C.11
Brugnara, C.12
Lux, S.E.13
Pinkus, G.S.14
Pinkus, J.L.15
Kingsley, P.D.16
Palis, J.17
Fleming, M.D.18
Andrews, N.C.19
Zon, L.I.20
more..
-
74
-
-
20444416123
-
The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis
-
Donovan A, Lima CA, Pinkus JL, Pinkus GS, Zon LI, Robine S, and Andrews NC. The iron exporter ferroportin/Slc40a1 is essential for iron homeostasis. Cell Metab 1: 191-200, 2005.
-
(2005)
Cell Metab
, vol.1
, pp. 191-200
-
-
Donovan, A.1
Lima, C.A.2
Pinkus, J.L.3
Pinkus, G.S.4
Zon, L.I.5
Robine, S.6
Andrews, N.C.7
-
75
-
-
0242422377
-
Mitochondrial ferritin: A new player in iron metabolism
-
Drysdale J, Arosio P, Invernizzi R, Cazzola M, Volz A, Corsi B, Biasiotto G, and Levi S. Mitochondrial ferritin: a new player in iron metabolism. Blood Cells Mol Dis 29: 376-383, 2002.
-
(2002)
Blood Cells Mol Dis
, vol.29
, pp. 376-383
-
-
Drysdale, J.1
Arosio, P.2
Invernizzi, R.3
Cazzola, M.4
Volz, A.5
Corsi, B.6
Biasiotto, G.7
Levi, S.8
-
76
-
-
0033166453
-
A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin
-
Dubljevic V, Sali A, and Goding JW. A conserved RGD (Arg-Gly-Asp) motif in the transferrin receptor is required for binding to transferrin. Biochem J 341: 11-14, 1999.
-
(1999)
Biochem J
, vol.341
, pp. 11-14
-
-
Dubljevic, V.1
Sali, A.2
Goding, J.W.3
-
77
-
-
0029821176
-
Clinical and genetic abnormalities in patients with Friedreich's ataxia
-
Durr A, Cossee M, Agid Y, Campuzano V, Mignard C, Penet C, Mandel JL, Brice A, and Koenig M. Clinical and genetic abnormalities in patients with Friedreich's ataxia. N Engl J Med 335: 1169-1175, 1996.
-
(1996)
N Engl J Med
, vol.335
, pp. 1169-1175
-
-
Durr, A.1
Cossee, M.2
Agid, Y.3
Campuzano, V.4
Mignard, C.5
Penet, C.6
Mandel, J.L.7
Brice, A.8
Koenig, M.9
-
78
-
-
10744232491
-
Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives
-
Elmberg M, Hultcrantz R, Ekbom A, Brandt L, Olsson S, Olsson R, Lindgren S, Loof L, Stal P, Wallerstedt S, Almer S, Sandberg-Gertzen H, and Askling J. Cancer risk in patients with hereditary hemochromatosis and in their first-degree relatives. Gastroenterology 125: 1733-1741, 2003.
-
(2003)
Gastroenterology
, vol.125
, pp. 1733-1741
-
-
Elmberg, M.1
Hultcrantz, R.2
Ekbom, A.3
Brandt, L.4
Olsson, S.5
Olsson, R.6
Lindgren, S.7
Loof, L.8
Stal, P.9
Wallerstedt, S.10
Almer, S.11
Sandberg-Gertzen, H.12
Askling, J.13
-
79
-
-
0033571363
-
H-ferritin subunit overexpression in erythroid cells reduces the oxidative stress response and induces multidrug resistance properties
-
Epsztejn S, Glickstein H, Picard V, Slotki IN, Breuer W, Beaumont C, and Cabantchik ZI. H-ferritin subunit overexpression in erythroid cells reduces the oxidative stress response and induces multidrug resistance properties. Blood 94: 3593-3603, 1999.
-
(1999)
Blood
, vol.94
, pp. 3593-3603
-
-
Epsztejn, S.1
Glickstein, H.2
Picard, V.3
Slotki, I.N.4
Breuer, W.5
Beaumont, C.6
Cabantchik, Z.I.7
-
80
-
-
0038727936
-
Description of Parkinson's disease as a clinical syndrome
-
Fahn S. Description of Parkinson's disease as a clinical syndrome. Ann N Y Acad Sci 991: 1-14, 2003.
-
(2003)
Ann N Y Acad Sci
, vol.991
, pp. 1-14
-
-
Fahn, S.1
-
81
-
-
0033583209
-
The B subunit of the CAAT-binding factor NFY binds the central segment of the Co-activator p300
-
Faniello MC, Bevilacqua MA, Condorelli G, de Crombrugghe B, Maity SN, Avvedimento VE, Cimino F, and Costanzo F. The B subunit of the CAAT-binding factor NFY binds the central segment of the Co-activator p300. J Biol Chem 274: 7623-7626, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 7623-7626
-
-
Faniello, M.C.1
Bevilacqua, M.A.2
Condorelli, G.3
de Crombrugghe, B.4
Maity, S.N.5
Avvedimento, V.E.6
Cimino, F.7
Costanzo, F.8
-
82
-
-
0025806510
-
Transcriptional regulation of the rat NAD(P)H:quinone reductase gene: Identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants
-
Favreau LV and Pickett CB. Transcriptional regulation of the rat NAD(P)H:quinone reductase gene: identification of regulatory elements controlling basal level expression and inducible expression by planar aromatic compounds and phenolic antioxidants. J Biol Chem 266: 4556-4561, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 4556-4561
-
-
Favreau, L.V.1
Pickett, C.B.2
-
83
-
-
9344224529
-
A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis
-
Feder JN, Gnirke A, Thomas W, Tsuchihashi Z, Ruddy DA, Basava A, Dormishian F, Domingo R Jr, Ellis MC, Fullan A, Hinton LM, Jones NL, Kimmel BE, Kronmal GS, Lauer P, Lee VK, Loeb DB, Mapa FA, McClelland E, Meyer NC, Mintier GA, Moeller N, Moore T, Morikang E, Prass CE, Quintana L, Starnes SM, Schatzman RC, Brunke KJ, Drayna DT, Risch NJ, Bacon BR, and Wolff RK. A novel MHC class I-like gene is mutated in patients with hereditary haemochromatosis. Nat Genet 13: 399-408, 1996.
-
(1996)
Nat Genet
, vol.13
, pp. 399-408
-
-
Feder, J.N.1
Gnirke, A.2
Thomas, W.3
Tsuchihashi, Z.4
Ruddy, D.A.5
Basava, A.6
Dormishian, F.7
Domingo Jr, R.8
Ellis, M.C.9
Fullan, A.10
Hinton, L.M.11
Jones, N.L.12
Kimmel, B.E.13
Kronmal, G.S.14
Lauer, P.15
Lee, V.K.16
Loeb, D.B.17
Mapa, F.A.18
McClelland, E.19
Meyer, N.C.20
Mintier, G.A.21
Moeller, N.22
Moore, T.23
Morikang, E.24
Prass, C.E.25
Quintana, L.26
Starnes, S.M.27
Schatzman, R.C.28
Brunke, K.J.29
Drayna, D.T.30
Risch, N.J.31
Bacon, B.R.32
Wolff, R.K.33
more..
-
84
-
-
13144282684
-
The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding
-
Feder JN, Penny DM, Irrinki A, Lee VK, Lebron JA, Watson N, Tsuchihashi Z, Sigal E, Bjorkman PJ, and Schatzman RC. The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding. Proc Natl Acad Sci U S A 95: 1472-1477, 1998.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1472-1477
-
-
Feder, J.N.1
Penny, D.M.2
Irrinki, A.3
Lee, V.K.4
Lebron, J.A.5
Watson, N.6
Tsuchihashi, Z.7
Sigal, E.8
Bjorkman, P.J.9
Schatzman, R.C.10
-
85
-
-
17644434333
-
The hemochromatosis founder mutation in HLAH disrupts beta2-microglobulin interaction and cell surface expression
-
Feder JN, Tsuchihashi Z, Irrinki A, Lee VK, Mapa FA, Morikang E, Prass CE, Starnes SM, Wolff RK, Parkkila S, Sly WS, and Schatzman RC. The hemochromatosis founder mutation in HLAH disrupts beta2-microglobulin interaction and cell surface expression. J Biol Chem 272: 14025-14028, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 14025-14028
-
-
Feder, J.N.1
Tsuchihashi, Z.2
Irrinki, A.3
Lee, V.K.4
Mapa, F.A.5
Morikang, E.6
Prass, C.E.7
Starnes, S.M.8
Wolff, R.K.9
Parkkila, S.10
Sly, W.S.11
Schatzman, R.C.12
-
86
-
-
0034603062
-
Early embryonic lethality of H ferritin gene deletion in mice
-
Ferreira C, Bucchini D, Martin ME, Levi S, Arosio P, Grandchamp B, and Beaumont C. Early embryonic lethality of H ferritin gene deletion in mice. J Biol Chem 275: 3021-3024, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 3021-3024
-
-
Ferreira, C.1
Bucchini, D.2
Martin, M.E.3
Levi, S.4
Arosio, P.5
Grandchamp, B.6
Beaumont, C.7
-
87
-
-
0035437188
-
-
Ferreira C, Santambrogio P, Martin ME, Andrieu V, Feldmann G, Hénin D, and Beaumont C. Blood 98: 525-532, 2001.
-
(2001)
Blood
, vol.98
, pp. 525-532
-
-
Ferreira, C.1
Santambrogio, P.2
Martin, M.E.3
Andrieu, V.4
Feldmann, G.5
Hénin, D.6
Beaumont, C.7
-
88
-
-
23844514701
-
Partial correction of sensitivity to oxidant stress in Friedreich ataxia patient fibroblasts by frataxin-encoding adeno-associated virus and lentivirus vectors
-
Fleming J, Spinoulas A, Zheng M, Cunningham SC, Ginn SL, McQuilty RC, Rowe PB, and Alexander IE. Partial correction of sensitivity to oxidant stress in Friedreich ataxia patient fibroblasts by frataxin-encoding adeno-associated virus and lentivirus vectors. Hum Gene Ther 16: 947-956, 2005.
-
(2005)
Hum Gene Ther
, vol.16
, pp. 947-956
-
-
Fleming, J.1
Spinoulas, A.2
Zheng, M.3
Cunningham, S.C.4
Ginn, S.L.5
McQuilty, R.C.6
Rowe, P.B.7
Alexander, I.E.8
-
89
-
-
0032477866
-
Nramp2 is mutated in the anemic Belgrade (b) rat: Evidence of a role for Nramp2 in endosomal iron transport
-
Fleming MD, Romano MA, Su MA, Garrick LM, Garrick MD, and Andrews NC. Nramp2 is mutated in the anemic Belgrade (b) rat: evidence of a role for Nramp2 in endosomal iron transport. Proc Natl Acad Sci U S A 95: 1148-1153, 1998.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 1148-1153
-
-
Fleming, M.D.1
Romano, M.A.2
Su, M.A.3
Garrick, L.M.4
Garrick, M.D.5
Andrews, N.C.6
-
90
-
-
0030763856
-
Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene
-
Fleming MD, Trenor CC, 3rd, Su MA, Foernzler D, Beier DR, Dietrich WF, and Andrews NC. Microcytic anaemia mice have a mutation in Nramp2, a candidate iron transporter gene. Nat Genet 16: 383-386, 1997.
-
(1997)
Nat Genet
, vol.16
, pp. 383-386
-
-
Fleming, M.D.1
Trenor 3rd, C.C.2
Su, M.A.3
Foernzler, D.4
Beier, D.R.5
Dietrich, W.F.6
Andrews, N.C.7
-
91
-
-
0036678091
-
Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis
-
Fleming RE, Ahmann JR, Migas MC, Waheed A, Koeffler HP, Kawabata H, Britton RS, Bacon BR, and Sly WS. Targeted mutagenesis of the murine transferrin receptor-2 gene produces hemochromatosis. Proc Natl Acad Sci U S A 99: 10653-10658, 2002.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 10653-10658
-
-
Fleming, R.E.1
Ahmann, J.R.2
Migas, M.C.3
Waheed, A.4
Koeffler, H.P.5
Kawabata, H.6
Britton, R.S.7
Bacon, B.R.8
Sly, W.S.9
-
92
-
-
0034007995
-
Transferrin receptor 2: Continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis
-
Fleming RE, Migas MC, Holden CC, Waheed A, Britton RS, Tomatsu S, Bacon BR, and Sly WS. Transferrin receptor 2: continued expression in mouse liver in the face of iron overload and in hereditary hemochromatosis. Proc Natl Acad Sci U S A 97: 2214-2219, 2000.
-
(2000)
Proc Natl Acad Sci U S A
, vol.97
, pp. 2214-2219
-
-
Fleming, R.E.1
Migas, M.C.2
Holden, C.C.3
Waheed, A.4
Britton, R.S.5
Tomatsu, S.6
Bacon, B.R.7
Sly, W.S.8
-
93
-
-
13044317291
-
Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: Increased duodenal expression of the iron transporter DMT1
-
Fleming RE, Migas MC, Zhou X, Jiang J, Britton RS, Brunt EM, Tomatsu S, Waheed A, Bacon BR, and Sly WS. Mechanism of increased iron absorption in murine model of hereditary hemochromatosis: increased duodenal expression of the iron transporter DMT1. Proc Natl Acad Sci U S A 96: 3143-3148, 1999.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 3143-3148
-
-
Fleming, R.E.1
Migas, M.C.2
Zhou, X.3
Jiang, J.4
Britton, R.S.5
Brunt, E.M.6
Tomatsu, S.7
Waheed, A.8
Bacon, B.R.9
Sly, W.S.10
-
94
-
-
0034883373
-
Ferroportin mutation in autosomal dominant hemochromatosis: Loss of function, gain in understanding
-
Fleming RE and Sly WS. Ferroportin mutation in autosomal dominant hemochromatosis: loss of function, gain in understanding. J Clin Invest 108: 521-522, 2001.
-
(2001)
J Clin Invest
, vol.108
, pp. 521-522
-
-
Fleming, R.E.1
Sly, W.S.2
-
95
-
-
0031567601
-
Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria
-
Foury F and Cazzalini O. Deletion of the yeast homologue of the human gene associated with Friedreich's ataxia elicits iron accumulation in mitochondria. FEBS Lett 411: 373-377, 1997.
-
(1997)
FEBS Lett
, vol.411
, pp. 373-377
-
-
Foury, F.1
Cazzalini, O.2
-
96
-
-
0037025331
-
Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain
-
Foury F and Roganti T. Deletion of the mitochondrial carrier genes MRS3 and MRS4 suppresses mitochondrial iron accumulation in a yeast frataxin-deficient strain. J Biol Chem 277: 24475-24483, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 24475-24483
-
-
Foury, F.1
Roganti, T.2
-
97
-
-
0025145723
-
Xenobiotic-inducible expression of murine glutathione S-transferase Ya sub-unit gene is controlled by an electrophile-responsive element
-
Friling RS, Bensimon A, Tichauer Y, and Daniel V. Xenobiotic-inducible expression of murine glutathione S-transferase Ya sub-unit gene is controlled by an electrophile-responsive element. Proc Natl Acad Sci U S A 87: 6258-6262, 1990.
-
(1990)
Proc Natl Acad Sci U S A
, vol.87
, pp. 6258-6262
-
-
Friling, R.S.1
Bensimon, A.2
Tichauer, Y.3
Daniel, V.4
-
98
-
-
0037188390
-
Physical evidence that yeast frataxin is an iron storage protein
-
Gakh O, Adamec J, Gacy AM, Twesten RD, Owen WG, and Isaya G. Physical evidence that yeast frataxin is an iron storage protein. Biochemistry 41: 6798-6804, 2002.
-
(2002)
Biochemistry
, vol.41
, pp. 6798-6804
-
-
Gakh, O.1
Adamec, J.2
Gacy, A.M.3
Twesten, R.D.4
Owen, W.G.5
Isaya, G.6
-
99
-
-
31544445770
-
Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity
-
Gakh O, Park S, Liu G, Macomber L, Imlay JA, Ferreira GC, and Isaya G. Mitochondrial iron detoxification is a primary function of frataxin that limits oxidative damage and preserves cell longevity. Hum Mol Genet 15: 467-479, 2006.
-
(2006)
Hum Mol Genet
, vol.15
, pp. 467-479
-
-
Gakh, O.1
Park, S.2
Liu, G.3
Macomber, L.4
Imlay, J.A.5
Ferreira, G.C.6
Isaya, G.7
-
100
-
-
0041672570
-
Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation
-
Ganz T. Hepcidin, a key regulator of iron metabolism and mediator of anemia of inflammation. Blood 102: 783-788, 2003.
-
(2003)
Blood
, vol.102
, pp. 783-788
-
-
Ganz, T.1
-
101
-
-
33644862202
-
Iron imports. IV. Hepcidin and regulation of body iron metabolism
-
Ganz T and Nemeth E. Iron imports. IV. Hepcidin and regulation of body iron metabolism. Am J Physiol Gastrointest Liver Physiol 290: G199-G203, 2006.
-
(2006)
Am J Physiol Gastrointest Liver Physiol
, vol.290
-
-
Ganz, T.1
Nemeth, E.2
-
102
-
-
0029919416
-
Ferritin uptake by human erythroid precursors is a regulated iron uptake pathway
-
Gelvan D, Fibach E, Meyron-Holtz EG, and Konijn AM. Ferritin uptake by human erythroid precursors is a regulated iron uptake pathway. Blood 88: 3200-3207, 1996.
-
(1996)
Blood
, vol.88
, pp. 3200-3207
-
-
Gelvan, D.1
Fibach, E.2
Meyron-Holtz, E.G.3
Konijn, A.M.4
-
103
-
-
4544346656
-
JunD reduces tumor angiogenesis by protecting cells from oxidative stress
-
Gerald D, Berra E, Frapart YM, Chan DA, Giaccia AJ, Mansuy D, Pouyssegur J, Yaniv M, and Mechta-Grigoriou F. JunD reduces tumor angiogenesis by protecting cells from oxidative stress. Cell 118: 781-794, 2004.
-
(2004)
Cell
, vol.118
, pp. 781-794
-
-
Gerald, D.1
Berra, E.2
Frapart, Y.M.3
Chan, D.A.4
Giaccia, A.J.5
Mansuy, D.6
Pouyssegur, J.7
Yaniv, M.8
Mechta-Grigoriou, F.9
-
104
-
-
0141623560
-
An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1
-
Gerber J, Muhlenhoff U, and Lill R. An interaction between frataxin and Isu1/Nfs1 that is crucial for Fe/S cluster synthesis on Isu1. EMBO Rep 4: 906-911, 2003.
-
(2003)
EMBO Rep
, vol.4
, pp. 906-911
-
-
Gerber, J.1
Muhlenhoff, U.2
Lill, R.3
-
105
-
-
0027438949
-
Domain closure in lactoferrin: Two hinges produce a see-saw motion between alternative close-packed interfaces
-
Gerstein M, Anderson BF, Norris GE, Baker EN, Lesk AM, and Chothia C. Domain closure in lactoferrin: two hinges produce a see-saw motion between alternative close-packed interfaces. J Mol Biol 234: 357-372, 1993.
-
(1993)
J Mol Biol
, vol.234
, pp. 357-372
-
-
Gerstein, M.1
Anderson, B.F.2
Norris, G.E.3
Baker, E.N.4
Lesk, A.M.5
Chothia, C.6
-
106
-
-
2942554825
-
HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface
-
Giannetti AM and Bjorkman PJ. HFE and transferrin directly compete for transferrin receptor in solution and at the cell surface. J Biol Chem 279: 25866-25875, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 25866-25875
-
-
Giannetti, A.M.1
Bjorkman, P.J.2
-
107
-
-
2442657217
-
Mechanism for multiple ligand recognition by the human transferrin receptor
-
Giannetti AM, Snow PM, Zak O, and Bjorkman PJ. Mechanism for multiple ligand recognition by the human transferrin receptor. PLoS Biol 1: E51, 2003.
-
(2003)
PLoS Biol
, vol.1
-
-
Giannetti, A.M.1
Snow, P.M.2
Zak, O.3
Bjorkman, P.J.4
-
109
-
-
26444566405
-
-
Gonzalez-Cabo P, Vazquez-Manrique RP, Garcia-Gimeno MA, Sanz P, and Palau F. Hum Mol Genet 14: 2091-2098, 2005.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 2091-2098
-
-
Gonzalez-Cabo, P.1
Vazquez-Manrique, R.P.2
Garcia-Gimeno, M.A.3
Sanz, P.4
Palau, F.5
-
110
-
-
0025089002
-
Translational repression by a complex between the iron-responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position-dependent in vivo
-
Goossen B, Caughman SW, Harford JB, Klausner RD, and Hentze MW. Translational repression by a complex between the iron-responsive element of ferritin mRNA and its specific cytoplasmic binding protein is position-dependent in vivo. EMBO J 9: 4127-4133, 1990.
-
(1990)
EMBO J
, vol.9
, pp. 4127-4133
-
-
Goossen, B.1
Caughman, S.W.2
Harford, J.B.3
Klausner, R.D.4
Hentze, M.W.5
-
111
-
-
0032695778
-
Maturation of frataxin within mammalian and yeast mitochondria: One-step processing by matrix processing peptidase
-
Gordon DM, Shi Q, Dancis A, and Pain D. Maturation of frataxin within mammalian and yeast mitochondria: one-step processing by matrix processing peptidase. Hum Mol Genet 8: 2255-2262, 1999.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 2255-2262
-
-
Gordon, D.M.1
Shi, Q.2
Dancis, A.3
Pain, D.4
-
112
-
-
33748796912
-
Rational selection of small molecules that increase transcription through the GAA repeats found in Friedreich's ataxia
-
Grant L, Sun J, Xu H, Subramony SH, Chaires JB, and Hebert MD. Rational selection of small molecules that increase transcription through the GAA repeats found in Friedreich's ataxia. FEBS Lett 580: 5399-5405, 2006.
-
(2006)
FEBS Lett
, vol.580
, pp. 5399-5405
-
-
Grant, L.1
Sun, J.2
Xu, H.3
Subramony, S.H.4
Chaires, J.B.5
Hebert, M.D.6
-
113
-
-
0038155128
-
Association of increased levels of heavy-chain ferritin with increased CD4+ CD25+ regulatory T-cell levels in patients with melanoma
-
Gray CP, Arosio P, and Hersey P. Association of increased levels of heavy-chain ferritin with increased CD4+ CD25+ regulatory T-cell levels in patients with melanoma. Clin Cancer Res 9: 2551-2559, 2003.
-
(2003)
Clin Cancer Res
, vol.9
, pp. 2551-2559
-
-
Gray, C.P.1
Arosio, P.2
Hersey, P.3
-
114
-
-
0036565874
-
Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells
-
Gray CP, Arosio P, and Hersey P. Heavy chain ferritin activates regulatory T cells by induction of changes in dendritic cells. Blood 99: 3326-3334, 2002.
-
(2002)
Blood
, vol.99
, pp. 3326-3334
-
-
Gray, C.P.1
Arosio, P.2
Hersey, P.3
-
115
-
-
0028059555
-
Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs
-
Gray NK and Hentze MW. Iron regulatory protein prevents binding of the 43S translation pre-initiation complex to ferritin and eALAS mRNAs. EMBO J 13: 3882-3891, 1994.
-
(1994)
EMBO J
, vol.13
, pp. 3882-3891
-
-
Gray, N.K.1
Hentze, M.W.2
-
116
-
-
12844275023
-
Ancient repeated DNA elements and the regulation of the human frataxin promoter
-
Greene E, Entezam A, Kumari D, and Usdin K. Ancient repeated DNA elements and the regulation of the human frataxin promoter. Genomics 85: 221-230, 2005.
-
(2005)
Genomics
, vol.85
, pp. 221-230
-
-
Greene, E.1
Entezam, A.2
Kumari, D.3
Usdin, K.4
-
117
-
-
0027462473
-
Metal-induced conformational changes in transferrins
-
Grossmann JG, Neu M, Evans RW, Lindley PF, Appel H, and Hasnain SS. Metal-induced conformational changes in transferrins. J Mol Biol 229: 585-590, 1993.
-
(1993)
J Mol Biol
, vol.229
, pp. 585-590
-
-
Grossmann, J.G.1
Neu, M.2
Evans, R.W.3
Lindley, P.F.4
Appel, H.5
Hasnain, S.S.6
-
118
-
-
0026720913
-
X-ray solution scattering reveals conformational changes upon iron uptake in lactoferrin, serum and ovo-transferrins
-
Grossmann JG, Neu M, Pantos E, Schwab FJ, Evans RW, Townes-Andrews E, Lindley PF, Appel H, Thies WG, and Hasnain SS. X-ray solution scattering reveals conformational changes upon iron uptake in lactoferrin, serum and ovo-transferrins. J Mol Biol 225: 811-819, 1992.
-
(1992)
J Mol Biol
, vol.225
, pp. 811-819
-
-
Grossmann, J.G.1
Neu, M.2
Pantos, E.3
Schwab, F.J.4
Evans, R.W.5
Townes-Andrews, E.6
Lindley, P.F.7
Appel, H.8
Thies, W.G.9
Hasnain, S.S.10
-
119
-
-
18244389488
-
Iron-dependent regulation of the divalent metal ion transporter
-
Gunshin H, Allerson CR, Polycarpou-Schwarz M, Rofts A, Rogers JT, Kishi F, Hentze MW, Rouault TA, Andrews NC, and Hediger MA. Iron-dependent regulation of the divalent metal ion transporter. FEBS Lett 509: 309-316, 2001.
-
(2001)
FEBS Lett
, vol.509
, pp. 309-316
-
-
Gunshin, H.1
Allerson, C.R.2
Polycarpou-Schwarz, M.3
Rofts, A.4
Rogers, J.T.5
Kishi, F.6
Hentze, M.W.7
Rouault, T.A.8
Andrews, N.C.9
Hediger, M.A.10
-
120
-
-
0030755366
-
Cloning and characterization of a mammalian proton-coupled metal-ion transporter
-
Gunshin H, Mackenzie B, Berger UV, Gunshin Y, Romero MF, Boron WF, Nussberger S, Gollan JL, and Hediger MA. Cloning and characterization of a mammalian proton-coupled metal-ion transporter. Nature 388: 482-488, 1997.
-
(1997)
Nature
, vol.388
, pp. 482-488
-
-
Gunshin, H.1
Mackenzie, B.2
Berger, U.V.3
Gunshin, Y.4
Romero, M.F.5
Boron, W.F.6
Nussberger, S.7
Gollan, J.L.8
Hediger, M.A.9
-
121
-
-
0026760413
-
Antioxidant protection against organic and inorganic oxygen radicals by normal human plasma: The important primary role for iron-binding and iron-oxidising proteins
-
Gutteridge JM and Quinlan GJ. Antioxidant protection against organic and inorganic oxygen radicals by normal human plasma: the important primary role for iron-binding and iron-oxidising proteins. Biochim Biophys Acta 1159: 248-254, 1992.
-
(1992)
Biochim Biophys Acta
, vol.1159
, pp. 248-254
-
-
Gutteridge, J.M.1
Quinlan, G.J.2
-
122
-
-
4644293303
-
Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration
-
Hahn P, Qian Y, Dentchev T, Chen L, Beard J, Harris ZL, and Dunaief JL. Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration. Proc Natl Acad Sci U S A 101: 13850-13855, 2004.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 13850-13855
-
-
Hahn, P.1
Qian, Y.2
Dentchev, T.3
Chen, L.4
Beard, J.5
Harris, Z.L.6
Dunaief, J.L.7
-
123
-
-
0034796353
-
Role of free radicals in the neurodegenerative diseases: Therapeutic implications for antioxidant treatment
-
Halliwell B. Role of free radicals in the neurodegenerative diseases: therapeutic implications for antioxidant treatment. Drugs Aging 18: 685-716, 2001.
-
(2001)
Drugs Aging
, vol.18
, pp. 685-716
-
-
Halliwell, B.1
-
124
-
-
34447263598
-
Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells
-
Han O and Kim EY. Colocalization of ferroportin-1 with hephaestin on the basolateral membrane of human intestinal absorptive cells. J Cell Biochem 101: 1000-1010, 2007.
-
(2007)
J Cell Biochem
, vol.101
, pp. 1000-1010
-
-
Han, O.1
Kim, E.Y.2
-
125
-
-
2942595705
-
A fungal multicopper oxidase restores iron homeostasis in aceruloplasminemia
-
Harris ZL, Davis-Kaplan SR, Gitlin JD, and Kaplan J. A fungal multicopper oxidase restores iron homeostasis in aceruloplasminemia. Blood 103: 4672-4673, 2004.
-
(2004)
Blood
, vol.103
, pp. 4672-4673
-
-
Harris, Z.L.1
Davis-Kaplan, S.R.2
Gitlin, J.D.3
Kaplan, J.4
-
126
-
-
0032875387
-
Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux
-
Harris ZL, Durley AP, Man TK, and Gitlin JD. Targeted gene disruption reveals an essential role for ceruloplasmin in cellular iron efflux. Proc Natl Acad Sci U S A 96: 10812-10817, 1999.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 10812-10817
-
-
Harris, Z.L.1
Durley, A.P.2
Man, T.K.3
Gitlin, J.D.4
-
127
-
-
0028903259
-
Aceruloplasminemia: Molecular characterization of this disorder of iron metabolism
-
Harris ZL, Takahashi Y, Miyajima H, Serizawa M, MacGillivray RT, and Gitlin JD. Aceruloplasminemia: molecular characterization of this disorder of iron metabolism. Proc Natl Acad Sci U S A 92: 2539-2543, 1995.
-
(1995)
Proc Natl Acad Sci U S A
, vol.92
, pp. 2539-2543
-
-
Harris, Z.L.1
Takahashi, Y.2
Miyajima, H.3
Serizawa, M.4
MacGillivray, R.T.5
Gitlin, J.D.6
-
128
-
-
0030608152
-
The ferritins: Molecular properties, iron storage function and cellular regulation
-
Harrison PM and Arosio P. The ferritins: molecular properties, iron storage function and cellular regulation. Biochim Biophys Acta 1275: 161-203, 1996.
-
(1996)
Biochim Biophys Acta
, vol.1275
, pp. 161-203
-
-
Harrison, P.M.1
Arosio, P.2
-
129
-
-
0033577159
-
Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro
-
Hashimoto M, Hsu LJ, Xia Y, Takeda A, Sisk A, Sundsmo M and Masliah E. Oxidative stress induces amyloid-like aggregate formation of NACP/alpha-synuclein in vitro. Neuroreport 10: 717-721, 1999.
-
(1999)
Neuroreport
, vol.10
, pp. 717-721
-
-
Hashimoto, M.1
Hsu, L.J.2
Xia, Y.3
Takeda, A.4
Sisk, A.5
Sundsmo, M.6
Masliah, E.7
-
130
-
-
0025865421
-
Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase
-
Hentze MW and Argos P. Homology between IRE-BP, a regulatory RNA-binding protein, aconitase, and isopropylmalate isomerase. Nucleic Acids Res 19: 1739-1740, 1991.
-
(1991)
Nucleic Acids Res
, vol.19
, pp. 1739-1740
-
-
Hentze, M.W.1
Argos, P.2
-
131
-
-
0024246416
-
A model for the structure and functions of iron-responsive elements
-
Hentze MW, Caughman SW, Casey JL, Koeller DM, Rouault TA, Harford JB, and Klausner RD. A model for the structure and functions of iron-responsive elements. Gene 72: 201-208, 1988.
-
(1988)
Gene
, vol.72
, pp. 201-208
-
-
Hentze, M.W.1
Caughman, S.W.2
Casey, J.L.3
Koeller, D.M.4
Rouault, T.A.5
Harford, J.B.6
Klausner, R.D.7
-
132
-
-
0023612118
-
Identification of the ironresponsive element for the translational regulation of human ferritin mRNA
-
Hentze MW, Caughman SW, Rouault TA, Barriocanal JG, Dancis A, Harford JB, and Klausner RD. Identification of the ironresponsive element for the translational regulation of human ferritin mRNA. Science 238: 1570-1573, 1987.
-
(1987)
Science
, vol.238
, pp. 1570-1573
-
-
Hentze, M.W.1
Caughman, S.W.2
Rouault, T.A.3
Barriocanal, J.G.4
Dancis, A.5
Harford, J.B.6
Klausner, R.D.7
-
133
-
-
0029758487
-
Molecular control of vertebrate iron metabolism: MRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress
-
Hentze MW and Kuhn LC. Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress. Proc Natl Acad Sci U S A 93: 8175-8182, 1996.
-
(1996)
Proc Natl Acad Sci U S A
, vol.93
, pp. 8175-8182
-
-
Hentze, M.W.1
Kuhn, L.C.2
-
134
-
-
2042546096
-
Balancing acts: Molecular control of mammalian iron metabolism
-
Hentze MW, Muckenthaler MU, and Andrews NC. Balancing acts: molecular control of mammalian iron metabolism. Cell 117: 285-297, 2004.
-
(2004)
Cell
, vol.117
, pp. 285-297
-
-
Hentze, M.W.1
Muckenthaler, M.U.2
Andrews, N.C.3
-
135
-
-
33748778745
-
Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia
-
Herman D, Jenssen K, Burnett R, Soragni E, Perlman SL, and Gottesfeld JM. Histone deacetylase inhibitors reverse gene silencing in Friedreich's ataxia. Nat Chem Biol 2: 551-558, 2006.
-
(2006)
Nat Chem Biol
, vol.2
, pp. 551-558
-
-
Herman, D.1
Jenssen, K.2
Burnett, R.3
Soragni, E.4
Perlman, S.L.5
Gottesfeld, J.M.6
-
136
-
-
27244457379
-
DNA and mRNA elements with complementary responses to hemin, antioxidant inducers, and iron control ferritin-L expression
-
Hintze KJ and Theil EC. DNA and mRNA elements with complementary responses to hemin, antioxidant inducers, and iron control ferritin-L expression. Proc Natl Acad Sci U S A 102: 15048-15052, 2005.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 15048-15052
-
-
Hintze, K.J.1
Theil, E.C.2
-
137
-
-
5444246509
-
Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease
-
Hochstrasser H, Bauer P, Walter U, Behnke S, Spiegel J, Csoti I, Zeiler B, Bornemann A, Pahnke J, Becker G, Riess O, and Berg D. Ceruloplasmin gene variations and substantia nigra hyperechogenicity in Parkinson disease. Neurology 63: 1912-1917, 2004.
-
(2004)
Neurology
, vol.63
, pp. 1912-1917
-
-
Hochstrasser, H.1
Bauer, P.2
Walter, U.3
Behnke, S.4
Spiegel, J.5
Csoti, I.6
Zeiler, B.7
Bornemann, A.8
Pahnke, J.9
Becker, G.10
Riess, O.11
Berg, D.12
-
138
-
-
27744446323
-
Functional relevance of ceruloplasmin mutations in Parkinson's disease
-
Hochstrasser H, Tomiuk J, Walter U, Behnke S, Spiegel J, Kruger R, Becker G, Riess O, and Berg D. Functional relevance of ceruloplasmin mutations in Parkinson's disease. FASEB J 19: 1851-1853, 2005.
-
(2005)
FASEB J
, vol.19
, pp. 1851-1853
-
-
Hochstrasser, H.1
Tomiuk, J.2
Walter, U.3
Behnke, S.4
Spiegel, J.5
Kruger, R.6
Becker, G.7
Riess, O.8
Berg, D.9
-
139
-
-
0038143287
-
Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons
-
Holtz WA and O'Malley KL. Parkinsonian mimetics induce aspects of unfolded protein response in death of dopaminergic neurons. J Biol Chem 278: 19367-19377, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 19367-19377
-
-
Holtz, W.A.1
O'Malley, K.L.2
-
140
-
-
0037126002
-
Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: Implications for regulation and cellular function
-
Hubert N and Hentze MW. Previously uncharacterized isoforms of divalent metal transporter (DMT)-1: implications for regulation and cellular function. Proc Natl Acad Sci U S A 99: 12345-12350, 2002.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 12345-12350
-
-
Hubert, N.1
Hentze, M.W.2
-
141
-
-
0033137124
-
Distribution of transferrin and ferritin binding in normal and multiple sclerotic human brains
-
Hulet SW, Powers S, and Connor JR. Distribution of transferrin and ferritin binding in normal and multiple sclerotic human brains. J Neurol Sci 165: 48-55, 1999.
-
(1999)
J Neurol Sci
, vol.165
, pp. 48-55
-
-
Hulet, S.W.1
Powers, S.2
Connor, J.R.3
-
142
-
-
0037020241
-
The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis
-
Hunter HN, Fulton DB, Ganz T, and Vogel HJ. The solution structure of human hepcidin, a peptide hormone with antimicrobial activity that is involved in iron uptake and hereditary hemochromatosis. J Biol Chem 277: 37597-37603, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 37597-37603
-
-
Hunter, H.N.1
Fulton, D.B.2
Ganz, T.3
Vogel, H.J.4
-
143
-
-
0032574765
-
Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins
-
Iwai K, Drake SK, Wehr NB, Weissman AM, LaVaute T, Minato N, Klausner RD, Levine RL, and Rouault TA. Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: implications for degradation of oxidized proteins. Proc Natl Acad Sci U S A 95: 4924-4928, 1998.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 4924-4928
-
-
Iwai, K.1
Drake, S.K.2
Wehr, N.B.3
Weissman, A.M.4
LaVaute, T.5
Minato, N.6
Klausner, R.D.7
Levine, R.L.8
Rouault, T.A.9
-
144
-
-
0028788316
-
Requirements for ironregulated degradation of the RNA binding protein, iron regulatory protein 2
-
Iwai K, Klausner RD, and Rouault TA. Requirements for ironregulated degradation of the RNA binding protein, iron regulatory protein 2. EMBO J 14: 5350-5357, 1995.
-
(1995)
EMBO J
, vol.14
, pp. 5350-5357
-
-
Iwai, K.1
Klausner, R.D.2
Rouault, T.A.3
-
145
-
-
34547927079
-
PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element
-
Iwasaki K, Hailemariam K, and Tsuji Y. PIAS3 interacts with ATF1 and regulates the human ferritin H gene through an antioxidant-responsive element. J Biol Chem 282: 22335-22343, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 22335-22343
-
-
Iwasaki, K.1
Hailemariam, K.2
Tsuji, Y.3
-
146
-
-
33645220567
-
Hemin-mediated regulation of an antioxidant-responsive element of the human ferritin H gene and role of Ref-1 during erythroid differentiation of K562 cells
-
Iwasaki K, Mackenzie EL, Hailemariam K, Sakamoto K, and Tsuji Y. Hemin-mediated regulation of an antioxidant-responsive element of the human ferritin H gene and role of Ref-1 during erythroid differentiation of K562 cells. Mol Cell Biol 26: 2845-2856, 2006.
-
(2006)
Mol Cell Biol
, vol.26
, pp. 2845-2856
-
-
Iwasaki, K.1
Mackenzie, E.L.2
Hailemariam, K.3
Sakamoto, K.4
Tsuji, Y.5
-
147
-
-
21144452241
-
Results of an international round robin for the quantification of serum non-transferrin-bound iron: Need for defining standardization and a clinically relevant isoform
-
Jacobs EM, Hendriks JC, van Tits BL, Evans PJ, Breuer W, Liu DY, Jansen EH, Jauhiainen K, Sturm B, Porter JB, Scheiber-Mojdehkar B, von Bonsdorff L, Cabantchik ZI, Hider RC, and Swinkels DW. Results of an international round robin for the quantification of serum non-transferrin-bound iron: need for defining standardization and a clinically relevant isoform. Anal Biochem 341: 241-250, 2005.
-
(2005)
Anal Biochem
, vol.341
, pp. 241-250
-
-
Jacobs, E.M.1
Hendriks, J.C.2
van Tits, B.L.3
Evans, P.J.4
Breuer, W.5
Liu, D.Y.6
Jansen, E.H.7
Jauhiainen, K.8
Sturm, B.9
Porter, J.B.10
Scheiber-Mojdehkar, B.11
von Bonsdorff, L.12
Cabantchik, Z.I.13
Hider, R.C.14
Swinkels, D.W.15
-
148
-
-
0348136710
-
Mitochondria-targeted antioxidants protect Friedreich ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants
-
Jauslin ML, Meier T, Smith RA, and Murphy MP. Mitochondria-targeted antioxidants protect Friedreich ataxia fibroblasts from endogenous oxidative stress more effectively than untargeted antioxidants. FASEB J 17: 1972-1974, 2003.
-
(2003)
FASEB J
, vol.17
, pp. 1972-1974
-
-
Jauslin, M.L.1
Meier, T.2
Smith, R.A.3
Murphy, M.P.4
-
149
-
-
1842836406
-
A cellular model for Friedreich ataxia reveals small-molecule glutathione peroxidase mimetics as novel treatment strategy
-
Jauslin ML, Wirth T, Meier T, and Schoumacher F. A cellular model for Friedreich ataxia reveals small-molecule glutathione peroxidase mimetics as novel treatment strategy. Hum Mol Genet 11: 3055-3063, 2002.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 3055-3063
-
-
Jauslin, M.L.1
Wirth, T.2
Meier, T.3
Schoumacher, F.4
-
150
-
-
0030294028
-
Haemochromatosis and HLA-H
-
Jazwinska EC, Cullen LM, Busfield F, Pyper WR, Webb SI, Powell LW, Morris CP, and Walsh TP. Haemochromatosis and HLA-H. Nat Genet 14: 249-251, 1996.
-
(1996)
Nat Genet
, vol.14
, pp. 249-251
-
-
Jazwinska, E.C.1
Cullen, L.M.2
Busfield, F.3
Pyper, W.R.4
Webb, S.I.5
Powell, L.W.6
Morris, C.P.7
Walsh, T.P.8
-
151
-
-
0038711587
-
Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system
-
Jeong SY and David S. Glycosylphosphatidylinositol-anchored ceruloplasmin is required for iron efflux from cells in the central nervous system. J Biol Chem 278: 27144-27148, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 27144-27148
-
-
Jeong, S.Y.1
David, S.2
-
152
-
-
10244265904
-
Diferric transferrin regulates transferrin receptor 2 protein stability
-
Johnson MB and Enns CA. Diferric transferrin regulates transferrin receptor 2 protein stability. Blood 104: 4287-4293, 2004.
-
(2004)
Blood
, vol.104
, pp. 4287-4293
-
-
Johnson, M.B.1
Enns, C.A.2
-
153
-
-
16144368650
-
Haemochromatosis and HLA-H
-
Jouanolle AM, Gandon G, Jezequel P, Blayau M, Campion ML, Yaouanq J, Mosser J, Fergelot P, Chauvel B, Bouric P, Carn G, Andrieux N, Gicquel I, Le Gall JY, and David V. Haemochromatosis and HLA-H. Nat Genet 14: 251-252, 1996.
-
(1996)
Nat Genet
, vol.14
, pp. 251-252
-
-
Jouanolle, A.M.1
Gandon, G.2
Jezequel, P.3
Blayau, M.4
Campion, M.L.5
Yaouanq, J.6
Mosser, J.7
Fergelot, P.8
Chauvel, B.9
Bouric, P.10
Carn, G.11
Andrieux, N.12
Gicquel, I.13
Le Gall, J.Y.14
David, V.15
-
154
-
-
33749265843
-
The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron
-
Karlberg T, Schagerlof U, Gakh O, Park S, Ryde U, Lindahl M, Leath K, Garman E, Isaya G, and Al-Karadaghi S. The structures of frataxin oligomers reveal the mechanism for the delivery and detoxification of iron. Structure 14: 1535-1546, 2006.
-
(2006)
Structure
, vol.14
, pp. 1535-1546
-
-
Karlberg, T.1
Schagerlof, U.2
Gakh, O.3
Park, S.4
Ryde, U.5
Lindahl, M.6
Leath, K.7
Garman, E.8
Isaya, G.9
Al-Karadaghi, S.10
-
155
-
-
0037093531
-
The mitochondrial protein frataxin prevents nuclear damage
-
Karthikeyan G, Lewis LK, and Resnick MA. The mitochondrial protein frataxin prevents nuclear damage. Hum Mol Genet 11: 1351-1362, 2002.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 1351-1362
-
-
Karthikeyan, G.1
Lewis, L.K.2
Resnick, M.A.3
-
156
-
-
0346752172
-
Reduction in frataxin causes progressive accumulation of mitochondrial damage
-
Karthikeyan G, Santos JH, Graziewicz MA, Copeland WC, Isaya G, Van Houten B, and Resnick MA. Reduction in frataxin causes progressive accumulation of mitochondrial damage. Hum Mol Genet 12: 3331-3342, 2003.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 3331-3342
-
-
Karthikeyan, G.1
Santos, J.H.2
Graziewicz, M.A.3
Copeland, W.C.4
Isaya, G.5
Van Houten, B.6
Resnick, M.A.7
-
157
-
-
0034964604
-
A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload
-
Kato J, Fujikawa K, Kanda M, Fukuda N, Sasaki K, Takayama T, Kobune M, Takada K, Takimoto R, Hamada H, Ikeda T, and Niitsu Y. A mutation, in the iron-responsive element of H ferritin mRNA, causing autosomal dominant iron overload. Am J Hum Genet 69: 191-197, 2001.
-
(2001)
Am J Hum Genet
, vol.69
, pp. 191-197
-
-
Kato, J.1
Fujikawa, K.2
Kanda, M.3
Fukuda, N.4
Sasaki, K.5
Takayama, T.6
Kobune, M.7
Takada, K.8
Takimoto, R.9
Hamada, H.10
Ikeda, T.11
Niitsu, Y.12
-
158
-
-
0036853914
-
Orchestrating the unfolded protein response in health and disease
-
Kaufman RJ. Orchestrating the unfolded protein response in health and disease. J Clin Invest 110: 1389-1398, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 1389-1398
-
-
Kaufman, R.J.1
-
159
-
-
3042654997
-
Does cellular iron dysregulation play a causative role in Parkinson's disease?
-
Kaur D and Andersen J. Does cellular iron dysregulation play a causative role in Parkinson's disease? Ageing Res Rev 3: 327-343, 2004.
-
(2004)
Ageing Res Rev
, vol.3
, pp. 327-343
-
-
Kaur, D.1
Andersen, J.2
-
160
-
-
0041733066
-
Ironing out Parkinson's disease: Is therapeutic treatment with iron chelators a real possibility?
-
Kaur D and Andersen JK. Ironing out Parkinson's disease: Is therapeutic treatment with iron chelators a real possibility? Aging Cell 1: 17-21, 2002.
-
(2002)
Aging Cell
, vol.1
, pp. 17-21
-
-
Kaur, D.1
Andersen, J.K.2
-
161
-
-
33847677727
-
Chronic ferritin expression within murine dopaminergic midbrain neurons results in a progressive age-related neurodegeneration
-
Kaur D, Rajagopalan S, Chinta S, Kumar J, Di Monte D, Cherny RA, and Andersen JK. Chronic ferritin expression within murine dopaminergic midbrain neurons results in a progressive age-related neurodegeneration. Brain Res 1140: 188-194, 2007.
-
(2007)
Brain Res
, vol.1140
, pp. 188-194
-
-
Kaur, D.1
Rajagopalan, S.2
Chinta, S.3
Kumar, J.4
Di Monte, D.5
Cherny, R.A.6
Andersen, J.K.7
-
162
-
-
0242684415
-
Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: A novel therapy for Parkinson's disease
-
Kaur D, Yantiri F, Rajagopalan S, Kumar J, Mo JQ, Boonplueang R, Viswanath V, Jacobs R, Yang L, Beal MF, DiMonte D, Volitaskis I, Ellerby L, Cherny RA, Bush AI, and Andersen JK. Genetic or pharmacological iron chelation prevents MPTP-induced neurotoxicity in vivo: a novel therapy for Parkinson's disease. Neuron 37: 899-909, 2003.
-
(2003)
Neuron
, vol.37
, pp. 899-909
-
-
Kaur, D.1
Yantiri, F.2
Rajagopalan, S.3
Kumar, J.4
Mo, J.Q.5
Boonplueang, R.6
Viswanath, V.7
Jacobs, R.8
Yang, L.9
Beal, M.F.10
DiMonte, D.11
Volitaskis, I.12
Ellerby, L.13
Cherny, R.A.14
Bush, A.I.15
Andersen, J.K.16
-
163
-
-
0033597780
-
Molecular cloning of transferrin receptor 2: A new member of the transferrin receptor-like family
-
Kawabata H, Yang R, Hirama T, Vuong PT, Kawano S, Gombart AF, and Koeffler HP. Molecular cloning of transferrin receptor 2: a new member of the transferrin receptor-like family. J Biol Chem 274: 20826-20832, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 20826-20832
-
-
Kawabata, H.1
Yang, R.2
Hirama, T.3
Vuong, P.T.4
Kawano, S.5
Gombart, A.F.6
Koeffler, H.P.7
-
164
-
-
0028929735
-
Translational repressor activity is equivalent and is quantitatively predicted by in vitro RNA binding for two iron-responsive element-binding proteins, IRP1 and IRP2
-
Kim HY, Klausner RD, and Rouault TA. Translational repressor activity is equivalent and is quantitatively predicted by in vitro RNA binding for two iron-responsive element-binding proteins, IRP1 and IRP2. J Biol Chem 270: 4983-4986, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 4983-4986
-
-
Kim, H.Y.1
Klausner, R.D.2
Rouault, T.A.3
-
165
-
-
0032540929
-
Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis
-
Knight SA, Sepuri NB, Pain D, and Dancis A. Mt-Hsp70 homolog, Ssc2p, required for maturation of yeast frataxin and mitochondrial iron homeostasis. J Biol Chem 273: 18389-18393, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 18389-18393
-
-
Knight, S.A.1
Sepuri, N.B.2
Pain, D.3
Dancis, A.4
-
166
-
-
13444252281
-
Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin
-
Knutson MD, Oukka M, Koss LM, Aydemir F, and Wessling-Resnick M. Iron release from macrophages after erythrophagocytosis is up-regulated by ferroportin 1 overexpression and down-regulated by hepcidin. Proc Natl Acad Sci U S A 102: 1324-1328, 2005.
-
(2005)
Proc Natl Acad Sci U S A
, vol.102
, pp. 1324-1328
-
-
Knutson, M.D.1
Oukka, M.2
Koss, L.M.3
Aydemir, F.4
Wessling-Resnick, M.5
-
167
-
-
0345688910
-
Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages
-
Knutson MD, Vafa MR, Haile DJ, and Wessling-Resnick M. Iron loading and erythrophagocytosis increase ferroportin 1 (FPN1) expression in J774 macrophages. Blood 102: 4191-4197, 2003.
-
(2003)
Blood
, vol.102
, pp. 4191-4197
-
-
Knutson, M.D.1
Vafa, M.R.2
Haile, D.J.3
Wessling-Resnick, M.4
-
168
-
-
0033568553
-
The cellular labile iron pool and intracellular ferritin in K562 cells
-
Konijn AM, Glickstein H, Vaisman B, Meyron-Holtz EG, Slotki IN, and Cabantchik ZI. The cellular labile iron pool and intracellular ferritin in K562 cells. Blood 94: 2128-2134, 1999.
-
(1999)
Blood
, vol.94
, pp. 2128-2134
-
-
Konijn, A.M.1
Glickstein, H.2
Vaisman, B.3
Meyron-Holtz, E.G.4
Slotki, I.N.5
Cabantchik, Z.I.6
-
169
-
-
0030813487
-
Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin
-
Koutnikova H, Campuzano V, Foury F, Dolle P, Cazzalini O, and Koenig M. Studies of human, mouse and yeast homologues indicate a mitochondrial function for frataxin. Nat Genet 16: 345-351, 1997.
-
(1997)
Nat Genet
, vol.16
, pp. 345-351
-
-
Koutnikova, H.1
Campuzano, V.2
Foury, F.3
Dolle, P.4
Cazzalini, O.5
Koenig, M.6
-
170
-
-
0031656903
-
Maturation of wild-type and mutated frataxin by the mitochondrial processing peptidase
-
Koutnikova H, Campuzano V, and Koenig M. Maturation of wild-type and mutated frataxin by the mitochondrial processing peptidase. Hum Mol Genet 7: 1485-1489, 1998.
-
(1998)
Hum Mol Genet
, vol.7
, pp. 1485-1489
-
-
Koutnikova, H.1
Campuzano, V.2
Koenig, M.3
-
171
-
-
0034284595
-
LEAP-1, a novel highly disulfidebonded human peptide, exhibits antimicrobial activity
-
Krause A, Neitz S, Magert HJ, Schulz A, Forssmann WG, Schulz-Knappe P, and Adermann K. LEAP-1, a novel highly disulfidebonded human peptide, exhibits antimicrobial activity. FEBS Lett 480: 147-150, 2000.
-
(2000)
FEBS Lett
, vol.480
, pp. 147-150
-
-
Krause, A.1
Neitz, S.2
Magert, H.J.3
Schulz, A.4
Forssmann, W.G.5
Schulz-Knappe, P.6
Adermann, K.7
-
172
-
-
0025736216
-
Endogenous iron excretion: A quantitative means to control iron metabolism?
-
Kreuzer M and Kirchgessner M. Endogenous iron excretion: a quantitative means to control iron metabolism? Biol Trace Elem Res 29: 77-92, 1991.
-
(1991)
Biol Trace Elem Res
, vol.29
, pp. 77-92
-
-
Kreuzer, M.1
Kirchgessner, M.2
-
173
-
-
0038143288
-
The TIM gene family: Emerging roles in immunity and disease
-
Kuchroo VK, Umetsu DT, DeKruyff RH, and Freeman GJ. The TIM gene family: emerging roles in immunity and disease. Nat Rev Immunol 3: 454-462, 2003.
-
(2003)
Nat Rev Immunol
, vol.3
, pp. 454-462
-
-
Kuchroo, V.K.1
Umetsu, D.T.2
DeKruyff, R.H.3
Freeman, G.J.4
-
174
-
-
0028981059
-
Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha
-
Kwak EL, Larochelle DA, Beaumont C, Torti SV, and Torti FM. Role for NF-kappa B in the regulation of ferritin H by tumor necrosis factor-alpha. J Biol Chem 270: 15285-15293, 1995.
-
(1995)
J Biol Chem
, vol.270
, pp. 15285-15293
-
-
Kwak, E.L.1
Larochelle, D.A.2
Beaumont, C.3
Torti, S.V.4
Torti, F.M.5
-
175
-
-
2942542658
-
Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala
-
Langlois d'Estaintot B, Santambrogio P, Granier T, Gallois B, Chevalier JM, Precigoux G, Levi S, and Arosio P. Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala. J Mol Biol 340: 277-293, 2004.
-
(2004)
J Mol Biol
, vol.340
, pp. 277-293
-
-
Langlois d'Estaintot, B.1
Santambrogio, P.2
Granier, T.3
Gallois, B.4
Chevalier, J.M.5
Precigoux, G.6
Levi, S.7
Arosio, P.8
-
176
-
-
3843101698
-
Neisseria meningitidis accelerates ferritin degradation in host epithelial cells to yield an essential iron source
-
Larson JA, Howie HL, and So M. Neisseria meningitidis accelerates ferritin degradation in host epithelial cells to yield an essential iron source. Mol Microbiol 53: 807-820, 2004.
-
(2004)
Mol Microbiol
, vol.53
, pp. 807-820
-
-
Larson, J.A.1
Howie, H.L.2
So, M.3
-
178
-
-
0035138456
-
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
-
LaVaute T, Smith S, Cooperman S, Iwai K, Land W, Meyron-Holtz E, Drake SK, Miller G, Abu-Asab M, Tsokos M, Switzer R 3rd, Grinberg A, Love P, Tresser N, and Rouault TA. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat Genet 27: 209-214, 2001.
-
(2001)
Nat Genet
, vol.27
, pp. 209-214
-
-
LaVaute, T.1
Smith, S.2
Cooperman, S.3
Iwai, K.4
Land, W.5
Meyron-Holtz, E.6
Drake, S.K.7
Miller, G.8
Abu-Asab, M.9
Tsokos, M.10
Switzer 3rd, R.11
Grinberg, A.12
Love, P.13
Tresser, N.14
Rouault, T.A.15
-
179
-
-
0033595794
-
Crystal structure of the ectodomain of human transferrin receptor
-
Lawrence CM, Ray S, Babyonyshev M, Galluser R, Borhani DW, and Harrison SC. Crystal structure of the ectodomain of human transferrin receptor. Science 286: 779-782, 1999.
-
(1999)
Science
, vol.286
, pp. 779-782
-
-
Lawrence, C.M.1
Ray, S.2
Babyonyshev, M.3
Galluser, R.4
Borhani, D.W.5
Harrison, S.C.6
-
180
-
-
0026059720
-
Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts
-
Lawson DM, Artymiuk PJ, Yewdall SJ, Smith JM, Livingstone JC, Treffry A, Luzzago A, Levi S, Arosio P, Cesareni G, Thomas CD, Shaw WV, and Harrison PM. Solving the structure of human H ferritin by genetically engineering intermolecular crystal contacts. Nature 349: 541-544, 1991.
-
(1991)
Nature
, vol.349
, pp. 541-544
-
-
Lawson, D.M.1
Artymiuk, P.J.2
Yewdall, S.J.3
Smith, J.M.4
Livingstone, J.C.5
Treffry, A.6
Luzzago, A.7
Levi, S.8
Arosio, P.9
Cesareni, G.10
Thomas, C.D.11
Shaw, W.V.12
Harrison, P.M.13
-
181
-
-
0024457179
-
Identification of the ferroxidase centre in ferritin
-
Lawson DM, Treffry A, Artymiuk PJ, Harrison PM, Yewdall SJ, Luzzago A, Cesareni G, Levi S, and Arosio P. Identification of the ferroxidase centre in ferritin. FEBS Lett 254: 207-210, 1989.
-
(1989)
FEBS Lett
, vol.254
, pp. 207-210
-
-
Lawson, D.M.1
Treffry, A.2
Artymiuk, P.J.3
Harrison, P.M.4
Yewdall, S.J.5
Luzzago, A.6
Cesareni, G.7
Levi, S.8
Arosio, P.9
-
182
-
-
0033585129
-
The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor
-
Lebron JA, West AP Jr, and Bjorkman PJ. The hemochromatosis protein HFE competes with transferrin for binding to the transferrin receptor. J Mol Biol 294: 239-245. 1999.
-
(1999)
J Mol Biol
, vol.294
, pp. 239-245
-
-
Lebron, J.A.1
West Jr, A.P.2
Bjorkman, P.J.3
-
183
-
-
33645326193
-
Iron dysregulation and neurodegeneration: The molecular connection
-
Lee DW, Andersen JK, and Kaur D. Iron dysregulation and neurodegeneration: the molecular connection. Mol Interv 6: 89-97, 2006.
-
(2006)
Mol Interv
, vol.6
, pp. 89-97
-
-
Lee, D.W.1
Andersen, J.K.2
Kaur, D.3
-
184
-
-
0037447390
-
Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1)
-
Lesuisse E, Santos R, Matzanke BF, Knight SA, Camadro JM, and Dancis A. Iron use for haeme synthesis is under control of the yeast frataxin homologue (Yfh1). Hum Mol Genet 12: 879-889, 2003.
-
(2003)
Hum Mol Genet
, vol.12
, pp. 879-889
-
-
Lesuisse, E.1
Santos, R.2
Matzanke, B.F.3
Knight, S.A.4
Camadro, J.M.5
Dancis, A.6
-
185
-
-
0035816608
-
A human mitochondrial ferritin encoded by an intronless gene
-
Levi S, Corsi B, Bosisio M, Invernizzi R, Volz A, Sanford D, Arosio P, and Drysdale J. A human mitochondrial ferritin encoded by an intronless gene. J Biol Chem 276: 24437-24440, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 24437-24440
-
-
Levi, S.1
Corsi, B.2
Bosisio, M.3
Invernizzi, R.4
Volz, A.5
Sanford, D.6
Arosio, P.7
Drysdale, J.8
-
186
-
-
0032100487
-
Analysis of ferritins in lymphoblastoid cell lines and in the lens of subjects with hereditary hyperferritinemia-cataract syndrome
-
Levi S, Girelli D, Perrone F, Pasti M, Beaumont C, Corrocher R, Albertini A, and Arosio P. Analysis of ferritins in lymphoblastoid cell lines and in the lens of subjects with hereditary hyperferritinemia-cataract syndrome. Blood 91: 4180-4187, 1998.
-
(1998)
Blood
, vol.91
, pp. 4180-4187
-
-
Levi, S.1
Girelli, D.2
Perrone, F.3
Pasti, M.4
Beaumont, C.5
Corrocher, R.6
Albertini, A.7
Arosio, P.8
-
187
-
-
0032959574
-
Transferrin receptor is necessary for development of erythrocytes and the nervous system
-
Levy JE, Jin O, Fujiwara Y, Kuo F, and Andrews NC. Transferrin receptor is necessary for development of erythrocytes and the nervous system. Nat Genet 21: 396-399, 1999.
-
(1999)
Nat Genet
, vol.21
, pp. 396-399
-
-
Levy, J.E.1
Jin, O.2
Fujiwara, Y.3
Kuo, F.4
Andrews, N.C.5
-
188
-
-
0026755187
-
Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element
-
Li Y and Jaiswal AK. Regulation of human NAD(P)H:quinone oxidoreductase gene. Role of AP1 binding site contained within human antioxidant response element. J Biol Chem 267: 15097-15104, 1992.
-
(1992)
J Biol Chem
, vol.267
, pp. 15097-15104
-
-
Li, Y.1
Jaiswal, A.K.2
-
189
-
-
0034891444
-
Expression of ferritin receptor in placental microvilli membrane in pregnant women with different iron status at mid-term gestation
-
Liao QK, Kong PA, Gao J, Li FY, and Qian ZM. Expression of ferritin receptor in placental microvilli membrane in pregnant women with different iron status at mid-term gestation. Eur J Clin Nutr 55: 651-656, 2001.
-
(2001)
Eur J Clin Nutr
, vol.55
, pp. 651-656
-
-
Liao, Q.K.1
Kong, P.A.2
Gao, J.3
Li, F.Y.4
Qian, Z.M.5
-
190
-
-
33751177803
-
Iron-sulfur protein biogenesis in eukaryotes: Components and mechanisms
-
Lill R and Muhlenhoff U. Iron-sulfur protein biogenesis in eukaryotes: components and mechanisms. Annu Rev Cell Dev Biol 22: 457-486, 2006.
-
(2006)
Annu Rev Cell Dev Biol
, vol.22
, pp. 457-486
-
-
Lill, R.1
Muhlenhoff, U.2
-
191
-
-
33748798494
-
Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells
-
Liuzzi JP, Aydemir F, Nam H, Knutson MD, and Cousins RJ. Zip14 (Slc39a14) mediates non-transferrin-bound iron uptake into cells. Proc Natl Acad Sci U S A 103: 13612-13617, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 13612-13617
-
-
Liuzzi, J.P.1
Aydemir, F.2
Nam, H.3
Knutson, M.D.4
Cousins, R.J.5
-
192
-
-
0033613262
-
Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia
-
Lodi R, Cooper JM, Bradley JL, Manners D, Styles P, Taylor DJ, and Schapira AH. Deficit of in vivo mitochondrial ATP production in patients with Friedreich ataxia. Proc Natl Acad Sci U S A 96: 11492-11495, 1999.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 11492-11495
-
-
Lodi, R.1
Cooper, J.M.2
Bradley, J.L.3
Manners, D.4
Styles, P.5
Taylor, D.J.6
Schapira, A.H.7
-
193
-
-
0000655498
-
Identification of a hypoxia response element in the transferrin receptor gene
-
Lok CN and Ponka P. Identification of a hypoxia response element in the transferrin receptor gene. J Biol Chem 274: 24147-24152, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 24147-24152
-
-
Lok, C.N.1
Ponka, P.2
-
194
-
-
33845693952
-
Frataxin knockdown causes loss of cytoplasmic iron-sulfur cluster functions, redox alterations and induction of heme transcripts
-
Lu C and Cortopassi G. Frataxin knockdown causes loss of cytoplasmic iron-sulfur cluster functions, redox alterations and induction of heme transcripts. Arch Biochem Biophys 457: 111-122, 2007.
-
(2007)
Arch Biochem Biophys
, vol.457
, pp. 111-122
-
-
Lu, C.1
Cortopassi, G.2
-
195
-
-
0020558254
-
Detection and isolation of a hepatic membrane receptor for ferritin
-
Mack U, Powell LW, and Halliday JW. Detection and isolation of a hepatic membrane receptor for ferritin. J Biol Chem 258: 4672-4675, 1983.
-
(1983)
J Biol Chem
, vol.258
, pp. 4672-4675
-
-
Mack, U.1
Powell, L.W.2
Halliday, J.W.3
-
196
-
-
0033525103
-
The high-resolution structure of the triplex formed by the GAA/TTC triplet repeat associated with Friedreich's ataxia
-
Mariappan SV, Catasti P, Silks LA 3rd, Bradbury EM, and Gupta G. The high-resolution structure of the triplex formed by the GAA/TTC triplet repeat associated with Friedreich's ataxia. J Mol Biol 285: 2035-2052, 1999.
-
(1999)
J Mol Biol
, vol.285
, pp. 2035-2052
-
-
Mariappan, S.V.1
Catasti, P.2
Silks 3rd, L.A.3
Bradbury, E.M.4
Gupta, G.5
-
197
-
-
0031017966
-
Transcriptional regulation of the ferritin heavy-chain gene: The activity of the CCAAT binding factor NF-Y is modulated in heme-treated Friend leukemia cells and during monocyte-to-macrophage differentiation
-
Marziali G, Perrotti E, Ilari R, Testa U, Coccia EM, and Battistini A. Transcriptional regulation of the ferritin heavy-chain gene: the activity of the CCAAT binding factor NF-Y is modulated in heme-treated Friend leukemia cells and during monocyte-to-macrophage differentiation. Mol Cell Biol 17: 1387-1395, 1997.
-
(1997)
Mol Cell Biol
, vol.17
, pp. 1387-1395
-
-
Marziali, G.1
Perrotti, E.2
Ilari, R.3
Testa, U.4
Coccia, E.M.5
Battistini, A.6
-
198
-
-
0035430282
-
Transcriptional regulation by the phosphorylation-dependent factor CREB
-
Mayr B and Montminy M. Transcriptional regulation by the phosphorylation-dependent factor CREB. Nat Rev Mol Cell Biol 2: 599-609, 2001.
-
(2001)
Nat Rev Mol Cell Biol
, vol.2
, pp. 599-609
-
-
Mayr, B.1
Montminy, M.2
-
199
-
-
0035204919
-
Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family
-
McIntire JJ, Umetsu SE, Akbari O, Potter M, Kuchroo VK, Barsh GS, Freeman GJ, Umetsu DT, and DeKruyff RH. Identification of Tapr (an airway hyperreactivity regulatory locus) and the linked Tim gene family. Nat Immunol 2: 1109-1116, 2001.
-
(2001)
Nat Immunol
, vol.2
, pp. 1109-1116
-
-
McIntire, J.J.1
Umetsu, S.E.2
Akbari, O.3
Potter, M.4
Kuchroo, V.K.5
Barsh, G.S.6
Freeman, G.J.7
Umetsu, D.T.8
DeKruyff, R.H.9
-
200
-
-
0035793856
-
An iron-regulated ferric reductase associated with the absorption of dietary iron
-
McKie AT, Barrow D, Latunde-Dada GO, Rolfs A, Sager G, Mudaly E, Mudaly M, Richardson C, Barlow D, Bomford A, Peters TJ, Raja KB, Shirali S, Hediger MA, Farzaneh F, and Simpson RJ. An iron-regulated ferric reductase associated with the absorption of dietary iron. Science 291: 1755-1759, 2001.
-
(2001)
Science
, vol.291
, pp. 1755-1759
-
-
McKie, A.T.1
Barrow, D.2
Latunde-Dada, G.O.3
Rolfs, A.4
Sager, G.5
Mudaly, E.6
Mudaly, M.7
Richardson, C.8
Barlow, D.9
Bomford, A.10
Peters, T.J.11
Raja, K.B.12
Shirali, S.13
Hediger, M.A.14
Farzaneh, F.15
Simpson, R.J.16
-
201
-
-
0033861745
-
A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation
-
McKie AT, Marciani P, Rolfs A, Brennan K, Wehr K, Barrow D, Miret S, Bomford A, Peters TJ, Farzaneh F, Hediger MA, Hentze MW, and Simpson RJ. A novel duodenal iron-regulated transporter, IREG1, implicated in the basolateral transfer of iron to the circulation. Mol Cell 5: 299-309, 2000.
-
(2000)
Mol Cell
, vol.5
, pp. 299-309
-
-
McKie, A.T.1
Marciani, P.2
Rolfs, A.3
Brennan, K.4
Wehr, K.5
Barrow, D.6
Miret, S.7
Bomford, A.8
Peters, T.J.9
Farzaneh, F.10
Hediger, M.A.11
Hentze, M.W.12
Simpson, R.J.13
-
202
-
-
10644232372
-
Oxidation-induced ferritin turnover in microglial cells: Role of proteasome
-
Mehlhase J, Sandig G, Pantopoulos K, and Grune T. Oxidation-induced ferritin turnover in microglial cells: role of proteasome. Free Radic Biol Med 38: 276-285, 2005.
-
(2005)
Free Radic Biol Med
, vol.38
, pp. 276-285
-
-
Mehlhase, J.1
Sandig, G.2
Pantopoulos, K.3
Grune, T.4
-
203
-
-
10744223491
-
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
-
Meyron-Holtz EG, Ghosh MC, Iwai K, LaVaute T, Brazzolotto X, Berger UV, Land W, Ollivierre-Wilson H, Grinberg A, Love P, and Rouault TA. Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis. EMBO J 23: 386-395, 2004.
-
(2004)
EMBO J
, vol.23
, pp. 386-395
-
-
Meyron-Holtz, E.G.1
Ghosh, M.C.2
Iwai, K.3
LaVaute, T.4
Brazzolotto, X.5
Berger, U.V.6
Land, W.7
Ollivierre-Wilson, H.8
Grinberg, A.9
Love, P.10
Rouault, T.A.11
-
204
-
-
0037592138
-
Ferritoid, a tissue-specific nuclear transport protein for ferritin in corneal epithelial cells
-
Millholland JM, Fitch JM, Cai CX, Gibney EP, Beazley KE, and Linsenmayer TF. Ferritoid, a tissue-specific nuclear transport protein for ferritin in corneal epithelial cells. J Biol Chem 278: 23963-23970, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 23963-23970
-
-
Millholland, J.M.1
Fitch, J.M.2
Cai, C.X.3
Gibney, E.P.4
Beazley, K.E.5
Linsenmayer, T.F.6
-
205
-
-
18244408334
-
Frataxin knockin mouse
-
Miranda CJ, Santos MM, Ohshima K, Smith J, Li L, Bunting M, Cossee M, Koenig M, Sequeiros J, Kaplan J, and Pandolfo M. Frataxin knockin mouse. FEBS Lett 512: 291-297, 2002.
-
(2002)
FEBS Lett
, vol.512
, pp. 291-297
-
-
Miranda, C.J.1
Santos, M.M.2
Ohshima, K.3
Smith, J.4
Li, L.5
Bunting, M.6
Cossee, M.7
Koenig, M.8
Sequeiros, J.9
Kaplan, J.10
Pandolfo, M.11
-
206
-
-
4143080503
-
Frataxin overexpressing mice
-
Miranda CJ, Santos MM, Ohshima K, Tessaro M, Sequeiros J, and Pandolfo M. Frataxin overexpressing mice. FEBS Lett 572: 281-288, 2004.
-
(2004)
FEBS Lett
, vol.572
, pp. 281-288
-
-
Miranda, C.J.1
Santos, M.M.2
Ohshima, K.3
Tessaro, M.4
Sequeiros, J.5
Pandolfo, M.6
-
207
-
-
33645827980
-
Characterization of mitochondrial ferritin in Drosophila
-
Missirlis F, Holmberg S, Georgieva T, Dunkov BC, Rouault TA, and Law JH. Characterization of mitochondrial ferritin in Drosophila. Proc Natl Acad Sci U S A 103: 5893-5898, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 5893-5898
-
-
Missirlis, F.1
Holmberg, S.2
Georgieva, T.3
Dunkov, B.C.4
Rouault, T.A.5
Law, J.H.6
-
208
-
-
17944380796
-
Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene
-
Montosi G, Donovan A, Totaro A, Garuti C, Pignatti E, Cassanelli S, Trenor CC, Gasparini P, Andrews NC, and Pietrangelo A. Autosomal-dominant hemochromatosis is associated with a mutation in the ferroportin (SLC11A3) gene. J Clin Invest 108: 619-623, 2001.
-
(2001)
J Clin Invest
, vol.108
, pp. 619-623
-
-
Montosi, G.1
Donovan, A.2
Totaro, A.3
Garuti, C.4
Pignatti, E.5
Cassanelli, S.6
Trenor, C.C.7
Gasparini, P.8
Andrews, N.C.9
Pietrangelo, A.10
-
209
-
-
1842504357
-
The metabolism of neuronal iron and its pathogenic role in neurological disease: Review
-
Moos T and Morgan EH. The metabolism of neuronal iron and its pathogenic role in neurological disease: review. Ann N Y Acad Sci 1012: 14-26, 2004.
-
(2004)
Ann N Y Acad Sci
, vol.1012
, pp. 14-26
-
-
Moos, T.1
Morgan, E.H.2
-
210
-
-
0034716887
-
Tripartite management of unfolded proteins in the endoplasmic reticulum
-
Mori K. Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 101: 451-454, 2000.
-
(2000)
Cell
, vol.101
, pp. 451-454
-
-
Mori, K.1
-
211
-
-
0026705752
-
Functional roles of the ferritin receptors of human liver, hepatoma, lymphoid and erythroid cells
-
Moss D, Fargion S, Fracanzani AL, Levi S, Cappellini MD, Arosio P, Powell LW, and Halliday JW. Functional roles of the ferritin receptors of human liver, hepatoma, lymphoid and erythroid cells. J Inorg Biochem 47: 219-227, 1992.
-
(1992)
J Inorg Biochem
, vol.47
, pp. 219-227
-
-
Moss, D.1
Fargion, S.2
Fracanzani, A.L.3
Levi, S.4
Cappellini, M.D.5
Arosio, P.6
Powell, L.W.7
Halliday, J.W.8
-
212
-
-
0037101845
-
The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins
-
Muhlenhoff U, Richhardt N, Ristow M, Kispal G, and Lill R. The yeast frataxin homolog Yfh1p plays a specific role in the maturation of cellular Fe/S proteins. Hum Mol Genet 11: 2025-2036, 2002.
-
(2002)
Hum Mol Genet
, vol.11
, pp. 2025-2036
-
-
Muhlenhoff, U.1
Richhardt, N.2
Ristow, M.3
Kispal, G.4
Lill, R.5
-
213
-
-
0021346479
-
Evidence for heterogeneity in hereditary hemochromatosis: Evaluation of 174 persons in nine families
-
Muir WA, McLaren GD, Braun W, and Askari A. Evidence for heterogeneity in hereditary hemochromatosis: evaluation of 174 persons in nine families. Am J Med 76: 806-814, 1984.
-
(1984)
Am J Med
, vol.76
, pp. 806-814
-
-
Muir, W.A.1
McLaren, G.D.2
Braun, W.3
Askari, A.4
-
214
-
-
0024276911
-
A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm
-
Mullner EW and Kuhn LC. A stem-loop in the 3′ untranslated region mediates iron-dependent regulation of transferrin receptor mRNA stability in the cytoplasm. Cell 53: 815-825, 1988.
-
(1988)
Cell
, vol.53
, pp. 815-825
-
-
Mullner, E.W.1
Kuhn, L.C.2
-
215
-
-
0034661480
-
Towards a structural understanding of Friedreich's ataxia: The solution structure of frataxin
-
Musco G, Stier G, Kolmerer B, Adinolfi S, Martin S, Frenkiel T, Gibson T, and Pastore A. Towards a structural understanding of Friedreich's ataxia: the solution structure of frataxin. Structure 8: 695-707, 2000.
-
(2000)
Structure
, vol.8
, pp. 695-707
-
-
Musco, G.1
Stier, G.2
Kolmerer, B.3
Adinolfi, S.4
Martin, S.5
Frenkiel, T.6
Gibson, T.7
Pastore, A.8
-
216
-
-
30144432585
-
The N-terminus of hepcidin is essential for its interaction with ferroportin: Structure-function study
-
Nemeth E, Preza GC, Jung CL, Kaplan J, Waring AJ, and Ganz T. The N-terminus of hepcidin is essential for its interaction with ferroportin: structure-function study. Blood 107: 328-333, 2006.
-
(2006)
Blood
, vol.107
, pp. 328-333
-
-
Nemeth, E.1
Preza, G.C.2
Jung, C.L.3
Kaplan, J.4
Waring, A.J.5
Ganz, T.6
-
217
-
-
2342510407
-
-
Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, and Ganz T. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 113: 1271-1276, 2004.
-
Nemeth E, Rivera S, Gabayan V, Keller C, Taudorf S, Pedersen BK, and Ganz T. IL-6 mediates hypoferremia of inflammation by inducing the synthesis of the iron regulatory hormone hepcidin. J Clin Invest 113: 1271-1276, 2004.
-
-
-
-
218
-
-
10844258104
-
Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization
-
Nemeth E, Tuttle MS, Powelson J, Vaughn MB, Donovan A, Ward DM, Ganz T, and Kaplan J. Hepcidin regulates cellular iron efflux by binding to ferroportin and inducing its internalization. Science 306: 2090-2093, 2004.
-
(2004)
Science
, vol.306
, pp. 2090-2093
-
-
Nemeth, E.1
Tuttle, M.S.2
Powelson, J.3
Vaughn, M.B.4
Donovan, A.5
Ward, D.M.6
Ganz, T.7
Kaplan, J.8
-
219
-
-
0035902605
-
-
Nicolas G, Bennoun M, Devaux I, Beaumont C, Grandchamp B, Kahn A, and Vaulont S. Proc Natl Acad Sci USA 98: 8780-8785, 2001.
-
(2001)
Proc Natl Acad Sci USA
, vol.98
, pp. 8780-8785
-
-
Nicolas, G.1
Bennoun, M.2
Devaux, I.3
Beaumont, C.4
Grandchamp, B.5
Kahn, A.6
Vaulont, S.7
-
220
-
-
0036791486
-
The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation
-
Nicolas G, Chauvet C, Viatte L, Danan JL, Bigard X, Devaux I, Beaumont C, Kahn A, and Vaulont S. The gene encoding the iron regulatory peptide hepcidin is regulated by anemia, hypoxia, and inflammation. J Clin Invest 110: 1037-1044, 2002.
-
(2002)
J Clin Invest
, vol.110
, pp. 1037-1044
-
-
Nicolas, G.1
Chauvet, C.2
Viatte, L.3
Danan, J.L.4
Bigard, X.5
Devaux, I.6
Beaumont, C.7
Kahn, A.8
Vaulont, S.9
-
221
-
-
23644444316
-
Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload
-
Niederkofler V, Salie R, and Arber S. Hemojuvelin is essential for dietary iron sensing, and its mutation leads to severe iron overload. J Clin Invest 115: 2180-2186, 2005.
-
(2005)
J Clin Invest
, vol.115
, pp. 2180-2186
-
-
Niederkofler, V.1
Salie, R.2
Arber, S.3
-
222
-
-
0034930197
-
A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis
-
Njajou OT, Vaessen N, Joosse M, Berghuis B, van Dongen JW, Breuning MH, Snijders PJ, Rutten WP, Sandkuijl LA, Oostra BA, van Duijn CM, and Heutink P. A mutation in SLC11A3 is associated with autosomal dominant hemochromatosis. Nat Genet 28: 213-214, 2001.
-
(2001)
Nat Genet
, vol.28
, pp. 213-214
-
-
Njajou, O.T.1
Vaessen, N.2
Joosse, M.3
Berghuis, B.4
van Dongen, J.W.5
Breuning, M.H.6
Snijders, P.J.7
Rutten, W.P.8
Sandkuijl, L.A.9
Oostra, B.A.10
van Duijn, C.M.11
Heutink, P.12
-
223
-
-
0346996450
-
Signal transduction of bone morphogenetic protein receptors
-
Nohe A, Keating E, Knaus P, and Petersen NO. Signal transduction of bone morphogenetic protein receptors. Cell Signal 16: 291-299, 2004.
-
(2004)
Cell Signal
, vol.16
, pp. 291-299
-
-
Nohe, A.1
Keating, E.2
Knaus, P.3
Petersen, N.O.4
-
224
-
-
34249034604
-
Individual dopaminergic neurons show raised iron levels in Parkinson disease
-
Oakley AE, Collingwood JF, Dobson J, Love G, Perrott HR, Edwardson JA, Elstner M, and Morris CM. Individual dopaminergic neurons show raised iron levels in Parkinson disease. Neurology 68: 1820-1825, 2007.
-
(2007)
Neurology
, vol.68
, pp. 1820-1825
-
-
Oakley, A.E.1
Collingwood, J.F.2
Dobson, J.3
Love, G.4
Perrott, H.R.5
Edwardson, J.A.6
Elstner, M.7
Morris, C.M.8
-
225
-
-
27644570377
-
-
Ohgami RS, Campagna DR, Antiochos B, Wood EB, Sharp JJ, Barker JE, and Fleming MD. nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouse. Blood 106: 3625-3631, 2005.
-
Ohgami RS, Campagna DR, Antiochos B, Wood EB, Sharp JJ, Barker JE, and Fleming MD. nm1054: a spontaneous, recessive, hypochromic, microcytic anemia mutation in the mouse. Blood 106: 3625-3631, 2005.
-
-
-
-
226
-
-
27644455133
-
Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells
-
Ohgami RS, Campagna DR, Greer EL, Antiochos B, McDonald A, Chen J, Sharp JJ, Fujiwara Y, Barker JE, and Fleming MD. Identification of a ferrireductase required for efficient transferrin-dependent iron uptake in erythroid cells. Nat Genet 37: 1264-1269, 2005.
-
(2005)
Nat Genet
, vol.37
, pp. 1264-1269
-
-
Ohgami, R.S.1
Campagna, D.R.2
Greer, E.L.3
Antiochos, B.4
McDonald, A.5
Chen, J.6
Sharp, J.J.7
Fujiwara, Y.8
Barker, J.E.9
Fleming, M.D.10
-
227
-
-
0032486276
-
Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo
-
Ohshima K, Montermini L, Wells RD, and Pandolfo M. Inhibitory effects of expanded GAA.TTC triplet repeats from intron I of the Friedreich ataxia gene on transcription and replication in vivo. J Biol Chem 273: 14588-14595, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 14588-14595
-
-
Ohshima, K.1
Montermini, L.2
Wells, R.D.3
Pandolfo, M.4
-
228
-
-
34249704041
-
Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin
-
Oktay Y, Dioum E, Matsuzaki S, Ding K, Yan LJ, Haller RG, Szweda LI, and Garcia JA. Hypoxia-inducible factor 2alpha regulates expression of the mitochondrial aconitase chaperone protein frataxin. J Biol Chem 282: 11750-11756, 2007.
-
(2007)
J Biol Chem
, vol.282
, pp. 11750-11756
-
-
Oktay, Y.1
Dioum, E.2
Matsuzaki, S.3
Ding, K.4
Yan, L.J.5
Haller, R.G.6
Szweda, L.I.7
Garcia, J.A.8
-
229
-
-
0024463596
-
Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene
-
Okuda A, Imagawa M, Maeda Y, Sakai M, and Muramatsu M. Structural and functional analysis of an enhancer GPEI having a phorbol 12-O-tetradecanoate 13-acetate responsive element-like sequence found in the rat glutathione transferase P gene. J Biol Chem 264: 16919-16926, 1989.
-
(1989)
J Biol Chem
, vol.264
, pp. 16919-16926
-
-
Okuda, A.1
Imagawa, M.2
Maeda, Y.3
Sakai, M.4
Muramatsu, M.5
-
230
-
-
0030863299
-
Nutrient deprivation of cultured rat hepatocytes increases the desferrioxamine-available iron pool and augments the sensitivity to hydrogen peroxide
-
Ollinger K and Roberg K. Nutrient deprivation of cultured rat hepatocytes increases the desferrioxamine-available iron pool and augments the sensitivity to hydrogen peroxide. J Biol Chem 272: 23707-23711, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 23707-23711
-
-
Ollinger, K.1
Roberg, K.2
-
231
-
-
0035397392
-
Ferritin and the response to oxidative stress
-
Orino K, Lehman L, Tsuji Y, Ayaki H, Torti SV, and Torti FM. Ferritin and the response to oxidative stress. Biochem J 357: 241-247, 2001.
-
(2001)
Biochem J
, vol.357
, pp. 241-247
-
-
Orino, K.1
Lehman, L.2
Tsuji, Y.3
Ayaki, H.4
Torti, S.V.5
Torti, F.M.6
-
232
-
-
0014011598
-
Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase (ceruloplasmin)
-
Osaki S. Kinetic studies of ferrous ion oxidation with crystalline human ferroxidase (ceruloplasmin). J Biol Chem 241: 5053-5059, 1966.
-
(1966)
J Biol Chem
, vol.241
, pp. 5053-5059
-
-
Osaki, S.1
-
234
-
-
9144252017
-
Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis
-
Papanikolaou G, Samuels ME, Ludwig EH, MacDonald ML, Franchini PL, Dube MP, Andres L, MacFarlane J, Sakellaropoulos N, Politou M, Nemeth E, Thompson J, Risler JK, Zaborowska C, Babakaiff R, Radomski CC, Pape TD, Davidas O, Christakis J, Brissot P, Lockitch G, Ganz T, Hayden MR, and Goldberg YP. Mutations in HFE2 cause iron overload in chromosome 1q-linked juvenile hemochromatosis. Nat Genet 36: 77-82, 2004.
-
(2004)
Nat Genet
, vol.36
, pp. 77-82
-
-
Papanikolaou, G.1
Samuels, M.E.2
Ludwig, E.H.3
MacDonald, M.L.4
Franchini, P.L.5
Dube, M.P.6
Andres, L.7
MacFarlane, J.8
Sakellaropoulos, N.9
Politou, M.10
Nemeth, E.11
Thompson, J.12
Risler, J.K.13
Zaborowska, C.14
Babakaiff, R.15
Radomski, C.C.16
Pape, T.D.17
Davidas, O.18
Christakis, J.19
Brissot, P.20
Lockitch, G.21
Ganz, T.22
Hayden, M.R.23
Goldberg, Y.P.24
more..
-
235
-
-
32944477219
-
Post-translational and transcriptional regulation of DMT1 during P19 embryonic carcinoma cell differentiation by retinoic acid
-
Paradkar PN and Roth JA. Post-translational and transcriptional regulation of DMT1 during P19 embryonic carcinoma cell differentiation by retinoic acid. Biochem J 394: 173-183, 2006.
-
(2006)
Biochem J
, vol.394
, pp. 173-183
-
-
Paradkar, P.N.1
Roth, J.A.2
-
236
-
-
0035896642
-
Hepcidin, a urinary antimicrobial peptide synthesized in the liver
-
Park CH, Valore EV, Waring AJ, and Ganz T. Hepcidin, a urinary antimicrobial peptide synthesized in the liver. J Biol Chem 276: 7806-7810, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 7806-7810
-
-
Park, C.H.1
Valore, E.V.2
Waring, A.J.3
Ganz, T.4
-
237
-
-
0037064027
-
The ferroxidase activity of yeast frataxin
-
Park S, Gakh O, Mooney SM, and Isaya G. The ferroxidase activity of yeast frataxin. J Biol Chem 277: 38589-38595, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 38589-38595
-
-
Park, S.1
Gakh, O.2
Mooney, S.M.3
Isaya, G.4
-
238
-
-
0042232045
-
Yeast frataxin sequentially chaperones and stores iron by coupling protein assembly with iron oxidation
-
Park S, Gakh O, O'Neill HA, Mangravita A, Nichol H, Ferreira GC, and Isaya G. Yeast frataxin sequentially chaperones and stores iron by coupling protein assembly with iron oxidation. J Biol Chem 278: 31340-31351, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 31340-31351
-
-
Park, S.1
Gakh, O.2
O'Neill, H.A.3
Mangravita, A.4
Nichol, H.5
Ferreira, G.C.6
Isaya, G.7
-
239
-
-
0030712463
-
Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis
-
Parkkila S, Waheed A, Britton RS, Bacon BR, Zhou XY, Tomatsu S, Fleming RE, and Sly WS. Association of the transferrin receptor in human placenta with HFE, the protein defective in hereditary hemochromatosis. Proc Natl Acad Sci U S A 94: 13198-13202, 1997.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 13198-13202
-
-
Parkkila, S.1
Waheed, A.2
Britton, R.S.3
Bacon, B.R.4
Zhou, X.Y.5
Tomatsu, S.6
Fleming, R.E.7
Sly, W.S.8
-
240
-
-
0142211205
-
Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: A potential role in the pathogenesis of the disease
-
Pastore A, Tozzi G, Gaeta LM, Bertini E, Serafini V, Di Cesare S, Bonetto V, Casoni F, Carrozzo R, Federici G, and Piemonte F. Actin glutathionylation increases in fibroblasts of patients with Friedreich's ataxia: a potential role in the pathogenesis of the disease. J Biol Chem 278: 42588-42595, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 42588-42595
-
-
Pastore, A.1
Tozzi, G.2
Gaeta, L.M.3
Bertini, E.4
Serafini, V.5
Di Cesare, S.6
Bonetto, V.7
Casoni, F.8
Carrozzo, R.9
Federici, G.10
Piemonte, F.11
-
241
-
-
0030856558
-
A novel glycosylphosphatidylinositol-anchored form of ceruloplasmin is expressed by mammalian astrocytes
-
Patel BN and David S. A novel glycosylphosphatidylinositol-anchored form of ceruloplasmin is expressed by mammalian astrocytes. J Biol Chem 272: 20185-20190, 1997.
-
(1997)
J Biol Chem
, vol.272
, pp. 20185-20190
-
-
Patel, B.N.1
David, S.2
-
242
-
-
0034635402
-
Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain
-
Patel BN, Dunn RJ, and David S. Alternative RNA splicing generates a glycosylphosphatidylinositol-anchored form of ceruloplasmin in mammalian brain. J Biol Chem 275: 4305-4310, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 4305-4310
-
-
Patel, B.N.1
Dunn, R.J.2
David, S.3
-
243
-
-
0036703490
-
Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury
-
Patel BN, Dunn RJ, Jeong SY, Zhu Q, Julien JP, and David S. Ceruloplasmin regulates iron levels in the CNS and prevents free radical injury. J Neurosci 22: 6578-6586, 2002,
-
(2002)
J Neurosci
, vol.22
, pp. 6578-6586
-
-
Patel, B.N.1
Dunn, R.J.2
Jeong, S.Y.3
Zhu, Q.4
Julien, J.P.5
David, S.6
-
244
-
-
33845768987
-
Integrating cell-signalling pathways with NF-kappaB and IKK function
-
Perkins ND. Integrating cell-signalling pathways with NF-kappaB and IKK function. Nat Rev Mol Cell Biol 8: 49-62, 2007.
-
(2007)
Nat Rev Mol Cell Biol
, vol.8
, pp. 49-62
-
-
Perkins, N.D.1
-
246
-
-
34447120059
-
Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs)
-
Peyssonnaux C, Zinkernagel AS, Schuepbach RA, Rankin E, Vaulont S, Haase VH, Nizet V, and Johnson RS. Regulation of iron homeostasis by the hypoxia-inducible transcription factors (HIFs). J Clin Invest 117: 1926-1932, 2007.
-
(2007)
J Clin Invest
, vol.117
, pp. 1926-1932
-
-
Peyssonnaux, C.1
Zinkernagel, A.S.2
Schuepbach, R.A.3
Rankin, E.4
Vaulont, S.5
Haase, V.H.6
Nizet, V.7
Johnson, R.S.8
-
247
-
-
8344260568
-
Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species
-
Pham CG, Bubici C, Zazzeroni F, Papa S, Jones J, Alvarez K, Jayawardena S, De Smaele E, Cong R, Beaumont C, Torti FM, Torti SV, and Franzoso G. Ferritin heavy chain upregulation by NF-kappaB inhibits TNFalpha-induced apoptosis by suppressing reactive oxygen species. Cell 119: 529-542, 2004.
-
(2004)
Cell
, vol.119
, pp. 529-542
-
-
Pham, C.G.1
Bubici, C.2
Zazzeroni, F.3
Papa, S.4
Jones, J.5
Alvarez, K.6
Jayawardena, S.7
De Smaele, E.8
Cong, R.9
Beaumont, C.10
Torti, F.M.11
Torti, S.V.12
Franzoso, G.13
-
248
-
-
2542560427
-
Hereditary hemochromatosis: A new look at an old disease
-
Pietrangelo A. Hereditary hemochromatosis: a new look at an old disease. N Engl J Med 350: 2383-2397, 2004.
-
(2004)
N Engl J Med
, vol.350
, pp. 2383-2397
-
-
Pietrangelo, A.1
-
249
-
-
33846212344
-
STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo
-
Pietrangelo A, Dierssen U, Valli L, Garuti C, Rump A, Corradini E, Ernst M, Klein C, and Trautwein C. STAT3 is required for IL-6-gp130-dependent activation of hepcidin in vivo. Gastroenterology 132: 294-300, 2007.
-
(2007)
Gastroenterology
, vol.132
, pp. 294-300
-
-
Pietrangelo, A.1
Dierssen, U.2
Valli, L.3
Garuti, C.4
Rump, A.5
Corradini, E.6
Ernst, M.7
Klein, C.8
Trautwein, C.9
-
250
-
-
0037462675
-
Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones
-
Pietsch EC, Chan JY, Torti FM, and Torti SV. Nrf2 mediates the induction of ferritin H in response to xenobiotics and cancer chemopreventive dithiolethiones. J Biol Chem 278: 2361-2369, 2003.
-
(2003)
J Biol Chem
, vol.278
, pp. 2361-2369
-
-
Pietsch, E.C.1
Chan, J.Y.2
Torti, F.M.3
Torti, S.V.4
-
251
-
-
0035896581
-
A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload
-
Pigeon C, Ilyin G, Courselaud B, Leroyer P, Turlin B, Brissot P, and Loreal O. A new mouse liver-specific gene, encoding a protein homologous to human antimicrobial peptide hepcidin, is overexpressed during iron overload. J Biol Chem 276: 7811-7819, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 7811-7819
-
-
Pigeon, C.1
Ilyin, G.2
Courselaud, B.3
Leroyer, P.4
Turlin, B.5
Brissot, P.6
Loreal, O.7
-
252
-
-
0027165817
-
Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells
-
Pilz RB. Impaired erythroid-specific gene expression in cAMP-dependent protein kinase-deficient murine erythroleukemia cells. J Biol Chem 268: 20252-20258, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 20252-20258
-
-
Pilz, R.B.1
-
253
-
-
0031963449
-
Function and regulation of transferrin and ferritin
-
Ponka P, Beaumont C, and Richardson DR. Function and regulation of transferrin and ferritin. Semin Hematol 35: 35-54, 1998.
-
(1998)
Semin Hematol
, vol.35
, pp. 35-54
-
-
Ponka, P.1
Beaumont, C.2
Richardson, D.R.3
-
254
-
-
0016475892
-
Serum ferritin in patients with iron overload and with acute and chronic liver diseases
-
Prieto J, Barry M, and Sherlock S. Serum ferritin in patients with iron overload and with acute and chronic liver diseases. Gastroenterology 68: 525-533, 1975.
-
(1975)
Gastroenterology
, vol.68
, pp. 525-533
-
-
Prieto, J.1
Barry, M.2
Sherlock, S.3
-
255
-
-
0035138072
-
Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits
-
Puccio H, Simon D, Cossee M, Criqui-Filipe P, Tiziano F, Melki J, Hindelang C, Matyas R, Rustin P, and Koenig M. Mouse models for Friedreich ataxia exhibit cardiomyopathy, sensory nerve defect and Fe-S enzyme deficiency followed by intramitochondrial iron deposits. Nat Genet 27: 181-186, 2001.
-
(2001)
Nat Genet
, vol.27
, pp. 181-186
-
-
Puccio, H.1
Simon, D.2
Cossee, M.3
Criqui-Filipe, P.4
Tiziano, F.5
Melki, J.6
Hindelang, C.7
Matyas, R.8
Rustin, P.9
Koenig, M.10
-
256
-
-
0033582421
-
The yeast frataxin homologue mediates mitochondrial iron efflux: Evidence for a mitochondrial iron cycle
-
Radisky DC, Babcock MC, and Kaplan J. The yeast frataxin homologue mediates mitochondrial iron efflux: evidence for a mitochondrial iron cycle. J Biol Chem 274: 4497-4499, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 4497-4499
-
-
Radisky, D.C.1
Babcock, M.C.2
Kaplan, J.3
-
257
-
-
15244356847
-
Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice
-
Rangasamy T, Cho CY, Thimmulappa RK, Zhen L, Srisuma SS, Kensler TW, Yamamoto M, Petrache I, Tuder RM, and Biswal S. Genetic ablation of Nrf2 enhances susceptibility to cigarette smoke-induced emphysema in mice. J Clin Invest 114: 1248-1259, 2004.
-
(2004)
J Clin Invest
, vol.114
, pp. 1248-1259
-
-
Rangasamy, T.1
Cho, C.Y.2
Thimmulappa, R.K.3
Zhen, L.4
Srisuma, S.S.5
Kensler, T.W.6
Yamamoto, M.7
Petrache, I.8
Tuder, R.M.9
Biswal, S.10
-
258
-
-
22344438250
-
Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice
-
Rangasamy T, Guo J, Mitzner WA, Roman J, Singh A, Fryer AD, Yamamoto M, Kensler TW, Tuder RM, Georas SN, and Biswal S. Disruption of Nrf2 enhances susceptibility to severe airway inflammation and asthma in mice. J Exp Med 202: 47-59, 2005.
-
(2005)
J Exp Med
, vol.202
, pp. 47-59
-
-
Rangasamy, T.1
Guo, J.2
Mitzner, W.A.3
Roman, J.4
Singh, A.5
Fryer, A.D.6
Yamamoto, M.7
Kensler, T.W.8
Tuder, R.M.9
Georas, S.N.10
Biswal, S.11
-
259
-
-
0032212875
-
Comparative resistance of the 20S and 26S proteasome to oxidative stress
-
Reinheckel T, Sitte N, Ullrich O, Kuckelkorn U, Davies KJ. and Grune T. Comparative resistance of the 20S and 26S proteasome to oxidative stress. Biochem J 335: 637-642, 1998.
-
(1998)
Biochem J
, vol.335
, pp. 637-642
-
-
Reinheckel, T.1
Sitte, N.2
Ullrich, O.3
Kuckelkorn, U.4
Davies, K.J.5
Grune, T.6
-
260
-
-
33749134992
-
T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation
-
Rennert PD, Ichimura T, Sizing ID, Bailly V, Li Z, Rennard R, McCoon P, Pablo L, Miklasz S, Tarilonte L, and Bonventre JV. T cell, Ig domain, mucin domain-2 gene-deficient mice reveal a novel mechanism for the regulation of Th2 immune responses and airway inflammation. J Immunol 177: 4311-4321, 2006.
-
(2006)
J Immunol
, vol.177
, pp. 4311-4321
-
-
Rennert, P.D.1
Ichimura, T.2
Sizing, I.D.3
Bailly, V.4
Li, Z.5
Rennard, R.6
McCoon, P.7
Pablo, L.8
Miklasz, S.9
Tarilonte, L.10
Bonventre, J.V.11
-
261
-
-
0035978474
-
Development of potential iron chelators for the treatment of Friedreich's ataxia: Ligands that mobilize mitochondrial iron
-
Richardson DR, Mouralian C, Ponka P, and Becker E. Development of potential iron chelators for the treatment of Friedreich's ataxia: ligands that mobilize mitochondrial iron. Biochim Biophys Acta 1536: 133-140, 2001.
-
(2001)
Biochim Biophys Acta
, vol.1536
, pp. 133-140
-
-
Richardson, D.R.1
Mouralian, C.2
Ponka, P.3
Becker, E.4
-
262
-
-
24744458603
-
Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs
-
Rivera S, Nemeth E, Gabayan V, Lopez MA, Farshidi D, and Ganz T. Synthetic hepcidin causes rapid dose-dependent hypoferremia and is concentrated in ferroportin-containing organs. Blood 106: 2196-2199, 2005.
-
(2005)
Blood
, vol.106
, pp. 2196-2199
-
-
Rivera, S.1
Nemeth, E.2
Gabayan, V.3
Lopez, M.A.4
Farshidi, D.5
Ganz, T.6
-
263
-
-
20244388240
-
Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis
-
Roetto A, Papanikolaou G, Politou M, Alberti F, Girelli D, Christakis J, Loukopoulos D, and Camaschella C. Mutant antimicrobial peptide hepcidin is associated with severe juvenile hemochromatosis. Nat Genet 33: 21-22, 2003.
-
(2003)
Nat Genet
, vol.33
, pp. 21-22
-
-
Roetto, A.1
Papanikolaou, G.2
Politou, M.3
Alberti, F.4
Girelli, D.5
Christakis, J.6
Loukopoulos, D.7
Camaschella, C.8
-
264
-
-
0347928847
-
An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript
-
Rogers JT, Randall JD, Cahill CM, Eder PS, Huang X, Gunshin H, Leiter L, McPhee J, Sarang SS, Utsuki T, Greig NH, Lahiri DK, Tanzi RE, Bush AI, Giordano T, and Gullans SR. An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript. J Biol Chem 277: 45518-45528, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 45518-45528
-
-
Rogers, J.T.1
Randall, J.D.2
Cahill, C.M.3
Eder, P.S.4
Huang, X.5
Gunshin, H.6
Leiter, L.7
McPhee, J.8
Sarang, S.S.9
Utsuki, T.10
Greig, N.H.11
Lahiri, D.K.12
Tanzi, R.E.13
Bush, A.I.14
Giordano, T.15
Gullans, S.R.16
-
265
-
-
0031253821
-
Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia
-
Rotig A, de Lonlay P, Chretien D, Foury F, Koenig M, Sidi D, Munnich A, and Rustin P. Aconitase and mitochondrial iron-sulphur protein deficiency in Friedreich ataxia. Nat Genet 17: 215-217, 1997.
-
(1997)
Nat Genet
, vol.17
, pp. 215-217
-
-
Rotig, A.1
de Lonlay, P.2
Chretien, D.3
Foury, F.4
Koenig, M.5
Sidi, D.6
Munnich, A.7
Rustin, P.8
-
266
-
-
0023713448
-
Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA
-
Rouault TA, Hentze MW, Caughman SW, Harford JB, and Klausner RD. Binding of a cytosolic protein to the iron-responsive element of human ferritin messenger RNA. Science 241: 1207-1210, 1988.
-
(1988)
Science
, vol.241
, pp. 1207-1210
-
-
Rouault, T.A.1
Hentze, M.W.2
Caughman, S.W.3
Harford, J.B.4
Klausner, R.D.5
-
267
-
-
0026062191
-
Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: Functional implications
-
Rouault TA, Stout CD, Kaptain S, Harford JB, and Klausner RD. Structural relationship between an iron-regulated RNA-binding protein (IRE-BP) and aconitase: functional implications. Cell 64: 881-883, 1991.
-
(1991)
Cell
, vol.64
, pp. 881-883
-
-
Rouault, T.A.1
Stout, C.D.2
Kaptain, S.3
Harford, J.B.4
Klausner, R.D.5
-
268
-
-
33947719279
-
Potential therapeutic applications of autophagy
-
Rubinsztein DC, Gestwicki JE, Murphy LO, and Klionsky DJ. Potential therapeutic applications of autophagy. Nat Rev Drug Discov 6: 304-312, 2007.
-
(2007)
Nat Rev Drug Discov
, vol.6
, pp. 304-312
-
-
Rubinsztein, D.C.1
Gestwicki, J.E.2
Murphy, L.O.3
Klionsky, D.J.4
-
269
-
-
0025948113
-
The antioxidant responsive element: Activation by oxidative stress and identification of the DNA consensus sequence required for functional activity
-
Rushmore TH, Morton MR, and Pickett CB. The antioxidant responsive element: activation by oxidative stress and identification of the DNA consensus sequence required for functional activity. J Biol Chem 266: 11632-11639, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 11632-11639
-
-
Rushmore, T.H.1
Morton, M.R.2
Pickett, C.B.3
-
270
-
-
0037114971
-
Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease
-
Ryu EJ, Harding HP, Angelastro JM, Vitolo OV, Ron D, and Greene LA. Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease. J Neurosci 22: 10690-10698, 2002.
-
(2002)
J Neurosci
, vol.22
, pp. 10690-10698
-
-
Ryu, E.J.1
Harding, H.P.2
Angelastro, J.M.3
Vitolo, O.V.4
Ron, D.5
Greene, L.A.6
-
271
-
-
0033120042
-
Sticky DNA: Self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia
-
Sakamoto N, Chastain PD, Parniewski P, Ohshima K, Pandolfo M, Griffith JD, and Wells RD. Sticky DNA: self-association properties of long GAA.TTC repeats in R.R.Y triplex structures from Friedreich's ataxia. Mol Cell 3: 465-475, 1999.
-
(1999)
Mol Cell
, vol.3
, pp. 465-475
-
-
Sakamoto, N.1
Chastain, P.D.2
Parniewski, P.3
Ohshima, K.4
Pandolfo, M.5
Griffith, J.D.6
Wells, R.D.7
-
272
-
-
0035920101
-
Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription
-
Sakamoto N, Ohshima K, Montermini L, Pandolfo M, and Wells RD. Sticky DNA, a self-associated complex formed at long GAA*TTC repeats in intron 1 of the frataxin gene, inhibits transcription. J Biol Chem 276: 27171-27177, 2001.
-
(2001)
J Biol Chem
, vol.276
, pp. 27171-27177
-
-
Sakamoto, N.1
Ohshima, K.2
Montermini, L.3
Pandolfo, M.4
Wells, R.D.5
-
273
-
-
0029914953
-
Phosphorylation and activation of both iron regulatory proteins 1 and 2 in HL-60 cells
-
Schalinske KL and Eisenstein RS. Phosphorylation and activation of both iron regulatory proteins 1 and 2 in HL-60 cells. J Biol Chem 271: 7168-7176, 1996.
-
(1996)
J Biol Chem
, vol.271
, pp. 7168-7176
-
-
Schalinske, K.L.1
Eisenstein, R.S.2
-
274
-
-
29644442275
-
Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells
-
Schoenfeld RA, Napoli E, Wong A, Zhan S, Reutenauer L, Morin D, Buckpitt AR, Taroni F, Lonnerdal B, Ristow M, Puccio H, and Cortopassi GA. Frataxin deficiency alters heme pathway transcripts and decreases mitochondrial heme metabolites in mammalian cells. Hum Mol Genet 14: 3787-3799, 2005.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3787-3799
-
-
Schoenfeld, R.A.1
Napoli, E.2
Wong, A.3
Zhan, S.4
Reutenauer, L.5
Morin, D.6
Buckpitt, A.R.7
Taroni, F.8
Lonnerdal, B.9
Ristow, M.10
Puccio, H.11
Cortopassi, G.A.12
-
275
-
-
33646548593
-
Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis
-
Schranzhofer M, Schifrer M, Cabrera JA, Kopp S, Chiba P, Beug H, and Mullner EW. Remodeling the regulation of iron metabolism during erythroid differentiation to ensure efficient heme biosynthesis. Blood 107: 4159-4167, 2006.
-
(2006)
Blood
, vol.107
, pp. 4159-4167
-
-
Schranzhofer, M.1
Schifrer, M.2
Cabrera, J.A.3
Kopp, S.4
Chiba, P.5
Beug, H.6
Mullner, E.W.7
-
276
-
-
0035313697
-
HIF-1 and mechanisms of hypoxia sensing
-
Semenza GL. HIF-1 and mechanisms of hypoxia sensing. Curr Opin Cell Biol 13: 167-171, 2001.
-
(2001)
Curr Opin Cell Biol
, vol.13
, pp. 167-171
-
-
Semenza, G.L.1
-
277
-
-
14044273058
-
Friedreich ataxia: The oxidative stress paradox
-
Seznec H, Simon D, Bouton C, Reutenauer L, Hertzog A, Golik P, Procaccio V, Patel M, Drapier JC, Koenig M, and Puccio H. Friedreich ataxia: the oxidative stress paradox. Hum Mol Genet 14: 463-474, 2005.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 463-474
-
-
Seznec, H.1
Simon, D.2
Bouton, C.3
Reutenauer, L.4
Hertzog, A.5
Golik, P.6
Procaccio, V.7
Patel, M.8
Drapier, J.C.9
Koenig, M.10
Puccio, H.11
-
278
-
-
2542556601
-
Idebenone delays the onset of cardiac functional alteration without correction of Fe-S enzymes deficit in a mouse model for Friedreich ataxia
-
Seznec H, Simon D, Monassier L, Criqui-Filipe P, Gansmuller A, Rustin P, Koenig M, and Puccio H. Idebenone delays the onset of cardiac functional alteration without correction of Fe-S enzymes deficit in a mouse model for Friedreich ataxia. Hum Mol Genet 13: 1017-1024, 2004.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 1017-1024
-
-
Seznec, H.1
Simon, D.2
Monassier, L.3
Criqui-Filipe, P.4
Gansmuller, A.5
Rustin, P.6
Koenig, M.7
Puccio, H.8
-
279
-
-
12944260630
-
Serum ferritin level as a predictor of impaired growth and puberty in thalassemia major patients
-
Shalitin S, Carmi D, Weintrob N, Phillip M, Miskin H, Kornreich L, Zilber R, Yaniv I, and Tamary H. Serum ferritin level as a predictor of impaired growth and puberty in thalassemia major patients. Eur J Haematol 74: 93-100, 2005.
-
(2005)
Eur J Haematol
, vol.74
, pp. 93-100
-
-
Shalitin, S.1
Carmi, D.2
Weintrob, N.3
Phillip, M.4
Miskin, H.5
Kornreich, L.6
Zilber, R.7
Yaniv, I.8
Tamary, H.9
-
281
-
-
2442504779
-
1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide
-
Shang T, Kotamraju S, Kalivendi SV, Hillard CJ, and Kalyanaraman B. 1-Methyl-4-phenylpyridinium-induced apoptosis in cerebellar granule neurons is mediated by transferrin receptor iron-dependent depletion of tetrahydrobiopterin and neuronal nitric-oxide synthase-derived superoxide. J Biol Chem 279: 19099-19112, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 19099-19112
-
-
Shang, T.1
Kotamraju, S.2
Kalivendi, S.V.3
Hillard, C.J.4
Kalyanaraman, B.5
-
282
-
-
24144459870
-
Identification of an intestinal heme transporter
-
Shayeghi M, Latunde-Dada GO, Oakhill JS, Laftah AH, Takeuchi K, Halliday N, Khan Y, Warley A, McCann FE, Hider RC, Frazer DM, Anderson GJ, Vulpe CD, Simpson RJ, and McKie AT. Identification of an intestinal heme transporter. Cell 122: 789-801, 2005.
-
(2005)
Cell
, vol.122
, pp. 789-801
-
-
Shayeghi, M.1
Latunde-Dada, G.O.2
Oakhill, J.S.3
Laftah, A.H.4
Takeuchi, K.5
Halliday, N.6
Khan, Y.7
Warley, A.8
McCann, F.E.9
Hider, R.C.10
Frazer, D.M.11
Anderson, G.J.12
Vulpe, C.D.13
Simpson, R.J.14
McKie, A.T.15
-
283
-
-
34248371666
-
Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis
-
Silvestri L, Pagani A, Fazi C, Gerardi G, Levi S, Arosio P, and Camaschella C. Defective targeting of hemojuvelin to plasma membrane is a common pathogenetic mechanism in juvenile hemochromatosis. Blood 109: 4503-4510, 2007.
-
(2007)
Blood
, vol.109
, pp. 4503-4510
-
-
Silvestri, L.1
Pagani, A.2
Fazi, C.3
Gerardi, G.4
Levi, S.5
Arosio, P.6
Camaschella, C.7
-
284
-
-
1442324707
-
Friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia
-
Simon D, Seznec H, Gansmuller A, Carelle N, Weber P, Metzger D, Rustin P, Koenig M, and Puccio H. Friedreich ataxia mouse models with progressive cerebellar and sensory ataxia reveal autophagic neurodegeneration in dorsal root ganglia. J Neurosci 24: 1987-1995, 2004.
-
(2004)
J Neurosci
, vol.24
, pp. 1987-1995
-
-
Simon, D.1
Seznec, H.2
Gansmuller, A.3
Carelle, N.4
Weber, P.5
Metzger, D.6
Rustin, P.7
Koenig, M.8
Puccio, H.9
-
285
-
-
0032579795
-
Abnormal localization of iron regulatory protein in Alzheimer's disease
-
Smith MA, Wehr K, Harris PL, Siedlak SL, Connor JR and Perry G. Abnormal localization of iron regulatory protein in Alzheimer's disease. Brain Res 788: 232-236, 1998.
-
(1998)
Brain Res
, vol.788
, pp. 232-236
-
-
Smith, M.A.1
Wehr, K.2
Harris, P.L.3
Siedlak, S.L.4
Connor, J.R.5
Perry, G.6
-
286
-
-
9744248303
-
Iron-sulfur protein maturation in human cells: Evidence for a function of frataxin
-
Stehling O, Elsasser HP, Bruckel B, Muhlenhoff U, and Lill R. Iron-sulfur protein maturation in human cells: evidence for a function of frataxin. Hum Mol Genet 13: 3007-3015, 2004.
-
(2004)
Hum Mol Genet
, vol.13
, pp. 3007-3015
-
-
Stehling, O.1
Elsasser, H.P.2
Bruckel, B.3
Muhlenhoff, U.4
Lill, R.5
-
287
-
-
0035861889
-
Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3
-
Storch S, Kubler B, Honing S, Ackmann M, Zapf J, Blum W, and Braulke T. Transferrin binds insulin-like growth factors and affects binding properties of insulin-like growth factor binding protein-3. FEBS Lett 509: 395-398, 2001.
-
(2001)
FEBS Lett
, vol.509
, pp. 395-398
-
-
Storch, S.1
Kubler, B.2
Honing, S.3
Ackmann, M.4
Zapf, J.5
Blum, W.6
Braulke, T.7
-
288
-
-
14844337832
-
Friedreich's ataxia, no changes in mitochondrial labile iron in human lymphoblasts and fibroblasts: A decrease in antioxidative capacity?
-
Sturm B, Bistrich U, Schranzhofer M, Sarsero JP, Rauen U, Scheiber-Mojdehkar B, de Groot H, Ioannou P, and Petrat F. Friedreich's ataxia, no changes in mitochondrial labile iron in human lymphoblasts and fibroblasts: a decrease in antioxidative capacity? J Biol Chem 280: 6701-6708, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 6701-6708
-
-
Sturm, B.1
Bistrich, U.2
Schranzhofer, M.3
Sarsero, J.P.4
Rauen, U.5
Scheiber-Mojdehkar, B.6
de Groot, H.7
Ioannou, P.8
Petrat, F.9
-
289
-
-
27844526573
-
Recombinant human erythropoietin: Effects on frataxin expression in vitro
-
Sturm B, Stupphann D, Kaun C, Boesch S, Schranzhofer M, Wojta J, Goldenberg H, and Scheiber-Mojdehkar B. Recombinant human erythropoietin: effects on frataxin expression in vitro. Eur J Clin Invest 35: 711-717, 2005.
-
(2005)
Eur J Clin Invest
, vol.35
, pp. 711-717
-
-
Sturm, B.1
Stupphann, D.2
Kaun, C.3
Boesch, S.4
Schranzhofer, M.5
Wojta, J.6
Goldenberg, H.7
Scheiber-Mojdehkar, B.8
-
290
-
-
21744461905
-
Characterization of nuclear ferritin and mechanism of translocation
-
Surguladze N, Patton S, Cozzi A, Fried MG, and Connor JR. Characterization of nuclear ferritin and mechanism of translocation. Biochem J 388: 731-740, 2005.
-
(2005)
Biochem J
, vol.388
, pp. 731-740
-
-
Surguladze, N.1
Patton, S.2
Cozzi, A.3
Fried, M.G.4
Connor, J.R.5
-
291
-
-
0036906608
-
Alternative splicing regulates the subcellular localization of divalent metal transporter 1 isoforms
-
Tabuchi M, Tanaka N, Nishida-Kitayama J, Ohno H, and Kishi F. Alternative splicing regulates the subcellular localization of divalent metal transporter 1 isoforms. Mol Biol Cell 13: 4371-4387, 2002.
-
(2002)
Mol Biol Cell
, vol.13
, pp. 4371-4387
-
-
Tabuchi, M.1
Tanaka, N.2
Nishida-Kitayama, J.3
Ohno, H.4
Kishi, F.5
-
292
-
-
0034778511
-
Frataxin expression rescues mitochondrial dysfunctions in FRDA cells
-
Tan G, Chen LS, Lonnerdal B, Gellera C, Taroni FA, and Cortopassi GA. Frataxin expression rescues mitochondrial dysfunctions in FRDA cells. Hum Mol Genet 10: 2099-2107, 2001.
-
(2001)
Hum Mol Genet
, vol.10
, pp. 2099-2107
-
-
Tan, G.1
Chen, L.S.2
Lonnerdal, B.3
Gellera, C.4
Taroni, F.A.5
Cortopassi, G.A.6
-
293
-
-
22044434111
-
Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes
-
Tehranchi R, Invernizzi R, Grandien A, Zhivotovsky B, Fadeel B, Forsblom AM, Travaglino E, Samuelsson J, Hast R, Nilsson L, Cazzola M, Wibom R, and Hellstrom-Lindberg E. Aberrant mitochondrial iron distribution and maturation arrest characterize early erythroid precursors in low-risk myelodysplastic syndromes. Blood 106: 247-253, 2005.
-
(2005)
Blood
, vol.106
, pp. 247-253
-
-
Tehranchi, R.1
Invernizzi, R.2
Grandien, A.3
Zhivotovsky, B.4
Fadeel, B.5
Forsblom, A.M.6
Travaglino, E.7
Samuelsson, J.8
Hast, R.9
Nilsson, L.10
Cazzola, M.11
Wibom, R.12
Hellstrom-Lindberg, E.13
-
294
-
-
29644448054
-
Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice
-
Thierbach R, Schulz TJ, Isken F, Voigt A, Mietzner B, Drewes G, von Kleist-Retzow JC, Wiesner RJ, Magnuson MA, Puccio H, Pfeiffer AF, Steinberg P, and Ristow M. Targeted disruption of hepatic frataxin expression causes impaired mitochondrial function, decreased life span and tumor growth in mice. Hum Mol Genet 14: 3857-3864, 2005.
-
(2005)
Hum Mol Genet
, vol.14
, pp. 3857-3864
-
-
Thierbach, R.1
Schulz, T.J.2
Isken, F.3
Voigt, A.4
Mietzner, B.5
Drewes, G.6
von Kleist-Retzow, J.C.7
Wiesner, R.J.8
Magnuson, M.A.9
Puccio, H.10
Pfeiffer, A.F.11
Steinberg, P.12
Ristow, M.13
-
295
-
-
0037106099
-
Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray
-
Thimmulappa RK, Mai KH, Srisuma S, Kensler TW, Yamamoto M, and Biswal S. Identification of Nrf2-regulated genes induced by the chemopreventive agent sulforaphane by oligonucleotide microarray. Cancer Res 62: 5196-5203, 2002.
-
(2002)
Cancer Res
, vol.62
, pp. 5196-5203
-
-
Thimmulappa, R.K.1
Mai, K.H.2
Srisuma, S.3
Kensler, T.W.4
Yamamoto, M.5
Biswal, S.6
-
296
-
-
0037216723
-
Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress
-
Thompson K, Menzies S, Muckenthaler M, Torti FM, Wood T, Torti SV, Hentze MW, Beard J, and Connor J. Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress. J Neurosci Res 71: 46-63, 2003.
-
(2003)
J Neurosci Res
, vol.71
, pp. 46-63
-
-
Thompson, K.1
Menzies, S.2
Muckenthaler, M.3
Torti, F.M.4
Wood, T.5
Torti, S.V.6
Hentze, M.W.7
Beard, J.8
Connor, J.9
-
297
-
-
0037092516
-
Regulation, mechanisms and proposed function of ferritin translocation to cell nuclei
-
Thompson KJ, Fried MG, Ye Z, Boyer P, and Connor JR. Regulation, mechanisms and proposed function of ferritin translocation to cell nuclei. J Cell Sci 115: 2165-2177, 2002.
-
(2002)
J Cell Sci
, vol.115
, pp. 2165-2177
-
-
Thompson, K.J.1
Fried, M.G.2
Ye, Z.3
Boyer, P.4
Connor, J.R.5
-
298
-
-
0025094141
-
The role of transferrin in the mechanism of cellular iron uptake
-
Thorstensen K and Romslo I. The role of transferrin in the mechanism of cellular iron uptake. Biochem J 271: 1-9, 1990.
-
(1990)
Biochem J
, vol.271
, pp. 1-9
-
-
Thorstensen, K.1
Romslo, I.2
-
299
-
-
0024273458
-
The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene
-
Torti SV, Kwak EL, Miller SC, Miller LL, Ringold GM, Myambo KB, Young AP, and Torti FM. The molecular cloning and characterization of murine ferritin heavy chain, a tumor necrosis factor-inducible gene. J Biol Chem 263: 12638-12644, 1988.
-
(1988)
J Biol Chem
, vol.263
, pp. 12638-12644
-
-
Torti, S.V.1
Kwak, E.L.2
Miller, S.C.3
Miller, L.L.4
Ringold, G.M.5
Myambo, K.B.6
Young, A.P.7
Torti, F.M.8
-
300
-
-
0033548251
-
Hypoxia alters iron-regulatory protein-1 binding capacity and modulates cellular iron homeostasis in human hepatoma and erythroleukemia cells
-
Toth I, Yuan L, Rogers JT, Boyce H, and Bridges KR. Hypoxia alters iron-regulatory protein-1 binding capacity and modulates cellular iron homeostasis in human hepatoma and erythroleukemia cells. J Biol Chem 274: 4467-4473, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 4467-4473
-
-
Toth, I.1
Yuan, L.2
Rogers, J.T.3
Boyce, H.4
Bridges, K.R.5
-
301
-
-
33751517409
-
High-resolution X-ray structures of human apoferritin H-chain mutants correlated with their activity and metal-binding sites
-
Toussaint L, Bertrand L, Hue L, Crichton RR, and Declercq JP. High-resolution X-ray structures of human apoferritin H-chain mutants correlated with their activity and metal-binding sites. J Mol Biol 365: 440-452, 2007.
-
(2007)
J Mol Biol
, vol.365
, pp. 440-452
-
-
Toussaint, L.1
Bertrand, L.2
Hue, L.3
Crichton, R.R.4
Declercq, J.P.5
-
302
-
-
0031454793
-
Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron
-
Tran TN, Eubanks SK, Schaffer KJ, Zhou CY, and Linder MC. Secretion of ferritin by rat hepatoma cells and its regulation by inflammatory cytokines and iron. Blood 90: 4979-4986, 1997.
-
(1997)
Blood
, vol.90
, pp. 4979-4986
-
-
Tran, T.N.1
Eubanks, S.K.2
Schaffer, K.J.3
Zhou, C.Y.4
Linder, M.C.5
-
303
-
-
0037343705
-
Transferrin receptor 2: A new molecule in iron metabolism
-
Trinder D and Baker E. Transferrin receptor 2: a new molecule in iron metabolism. Int J Biochem Cell Biol 35: 292-296, 2003.
-
(2003)
Int J Biochem Cell Biol
, vol.35
, pp. 292-296
-
-
Trinder, D.1
Baker, E.2
-
304
-
-
0036077111
-
Molecular pathogenesis of iron overload
-
Trinder D, Fox C, Vautier G, and Olynyk JK. Molecular pathogenesis of iron overload. Gut 51: 290-295, 2002.
-
(2002)
Gut
, vol.51
, pp. 290-295
-
-
Trinder, D.1
Fox, C.2
Vautier, G.3
Olynyk, J.K.4
-
305
-
-
33745898241
-
Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6
-
Truksa J, Peng H, Lee P, and Beutler E. Bone morphogenetic proteins 2, 4, and 9 stimulate murine hepcidin 1 expression independently of Hfe, transferrin receptor 2 (Tfr2), and IL-6. Proc Natl Acad Sci U S A 103: 10289-10293, 2006.
-
(2006)
Proc Natl Acad Sci U S A
, vol.103
, pp. 10289-10293
-
-
Truksa, J.1
Peng, H.2
Lee, P.3
Beutler, E.4
-
306
-
-
27844572844
-
JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress
-
Tsuji Y. JunD activates transcription of the human ferritin H gene through an antioxidant response element during oxidative stress. Oncogene 24: 7567-7578, 2005.
-
(2005)
Oncogene
, vol.24
, pp. 7567-7578
-
-
Tsuji, Y.1
-
307
-
-
0029155970
-
FER-1, an enhancer of the ferritin H gene and a target of E1A-mediated transcriptional repression
-
Tsuji Y, Akebi N, Lam TK, Nakabeppu Y, Torti SV, and Torti FM. FER-1, an enhancer of the ferritin H gene and a target of E1A-mediated transcriptional repression. Mol Cell Biol 15: 5152-5164, 1995.
-
(1995)
Mol Cell Biol
, vol.15
, pp. 5152-5164
-
-
Tsuji, Y.1
Akebi, N.2
Lam, T.K.3
Nakabeppu, Y.4
Torti, S.V.5
Torti, F.M.6
-
308
-
-
0033853838
-
Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress
-
Tsuji Y, Ayaki H, Whitman SP, Morrow CS, Torti SV, and Torti FM. Coordinate transcriptional and translational regulation of ferritin in response to oxidative stress. Mol Cell Biol 20: 5818-5827, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 5818-5827
-
-
Tsuji, Y.1
Ayaki, H.2
Whitman, S.P.3
Morrow, C.S.4
Torti, S.V.5
Torti, F.M.6
-
309
-
-
0027450457
-
Preferential repression of the H subunit of ferritin by adenovirus E1A in NIH-3T3 mouse fibroblasts
-
Tsuji Y, Kwak E, Saika T, Torti SV, and Torti FM. Preferential repression of the H subunit of ferritin by adenovirus E1A in NIH-3T3 mouse fibroblasts. J Biol Chem 268: 7270-7275, 1993.
-
(1993)
J Biol Chem
, vol.268
, pp. 7270-7275
-
-
Tsuji, Y.1
Kwak, E.2
Saika, T.3
Torti, S.V.4
Torti, F.M.5
-
310
-
-
0025767108
-
Tumor necrosis factor-alpha and interleukin 1-alpha regulate transferrin receptor in human diploid fibroblasts: Relationship to the induction of ferritin heavy chain
-
Tsuji Y, Miller LL, Miller SC, Torti SV, and Torti FM. Tumor necrosis factor-alpha and interleukin 1-alpha regulate transferrin receptor in human diploid fibroblasts: relationship to the induction of ferritin heavy chain. J Biol Chem 266: 7257-7261, 1991.
-
(1991)
J Biol Chem
, vol.266
, pp. 7257-7261
-
-
Tsuji, Y.1
Miller, L.L.2
Miller, S.C.3
Torti, S.V.4
Torti, F.M.5
-
311
-
-
0033548662
-
Transcriptional regulation of the mouse ferritin H gene: Involvement of p300/CBP adaptor proteins in FER-1 enhancer activity
-
Tsuji Y, Moran E, Torti SV, and Torti FM. Transcriptional regulation of the mouse ferritin H gene: involvement of p300/CBP adaptor proteins in FER-1 enhancer activity. J Biol Chem 274: 7501-7507, 1999.
-
(1999)
J Biol Chem
, vol.274
, pp. 7501-7507
-
-
Tsuji, Y.1
Moran, E.2
Torti, S.V.3
Torti, F.M.4
-
312
-
-
0032579380
-
Activation of the ferritin H enhancer, FER-1, by the cooperative action of members of the AP1 and Sp1 transcription factor families
-
Tsuji Y, Torti SV, and Torti FM. Activation of the ferritin H enhancer, FER-1, by the cooperative action of members of the AP1 and Sp1 transcription factor families. J Biol Chem 273: 2984-2992, 1998.
-
(1998)
J Biol Chem
, vol.273
, pp. 2984-2992
-
-
Tsuji, Y.1
Torti, S.V.2
Torti, F.M.3
-
313
-
-
0141670832
-
3-Nitropropionic acid increases frataxin expression in human lymphoblasts and in transgenic rat PC12 cells
-
Turano M, Tammaro A, De Biase I, Lo Casale MS, Ruggiero G, Monticelli A, Cocozza S, and Pianese L. 3-Nitropropionic acid increases frataxin expression in human lymphoblasts and in transgenic rat PC12 cells. Neurosci Lett 350: 184-186, 2003.
-
(2003)
Neurosci Lett
, vol.350
, pp. 184-186
-
-
Turano, M.1
Tammaro, A.2
De Biase, I.3
Lo Casale, M.S.4
Ruggiero, G.5
Monticelli, A.6
Cocozza, S.7
Pianese, L.8
-
314
-
-
34247274205
-
The relationship between depression and serum ferritin level
-
Vahdat Shariatpanaahi M, Vahdat Shariatpanaahi Z, Moshtaaghi M, Shahbaazi SH, and Abadi A. The relationship between depression and serum ferritin level. Eur J Clin Nutr 61: 532-535, 2007.
-
(2007)
Eur J Clin Nutr
, vol.61
, pp. 532-535
-
-
Vahdat Shariatpanaahi, M.1
Vahdat Shariatpanaahi, Z.2
Moshtaaghi, M.3
Shahbaazi, S.H.4
Abadi, A.5
-
315
-
-
33845985236
-
STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation
-
Verga Falzacappa MV, Vujic Spasic M, Kessler R, Stolte J, Hentze MW, and Muckenthaler MU. STAT3 mediates hepatic hepcidin expression and its inflammatory stimulation. Blood 109: 353-358, 2007.
-
(2007)
Blood
, vol.109
, pp. 353-358
-
-
Verga Falzacappa, M.V.1
Vujic Spasic, M.2
Kessler, R.3
Stolte, J.4
Hentze, M.W.5
Muckenthaler, M.U.6
-
316
-
-
12144288949
-
Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a mutation in the ferritin light polypeptide gene
-
Vidal R, Ghetti B, Takao M, Brefel-Courbon C, Uro-Coste E, Glazier BS, Siani V, Benson MD, Calvas P, Miravalle L, Rascol O, and Delisle MB. Intracellular ferritin accumulation in neural and extraneural tissue characterizes a neurodegenerative disease associated with a mutation in the ferritin light polypeptide gene. J Neuropathol Exp Neurol 63: 363-380, 2004.
-
(2004)
J Neuropathol Exp Neurol
, vol.63
, pp. 363-380
-
-
Vidal, R.1
Ghetti, B.2
Takao, M.3
Brefel-Courbon, C.4
Uro-Coste, E.5
Glazier, B.S.6
Siani, V.7
Benson, M.D.8
Calvas, P.9
Miravalle, L.10
Rascol, O.11
Delisle, M.B.12
-
317
-
-
0034053969
-
Role of the mitochondrial Hsp70s, Ssc1 and Ssq1, in the maturation of Yfh1
-
Voisine C, Schilke B, Ohlson M, Beinert H, Marszalek J, and Craig EA. Role of the mitochondrial Hsp70s, Ssc1 and Ssq1, in the maturation of Yfh1. Mol Cell Biol 20: 3677-3684, 2000.
-
(2000)
Mol Cell Biol
, vol.20
, pp. 3677-3684
-
-
Voisine, C.1
Schilke, B.2
Ohlson, M.3
Beinert, H.4
Marszalek, J.5
Craig, E.A.6
-
318
-
-
0032909207
-
Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse
-
Vulpe CD, Kuo YM, Murphy TL, Cowley L, Askwith C, Libina N, Gitschier J and Anderson GJ. Hephaestin, a ceruloplasmin homologue implicated in intestinal iron transport, is defective in the sla mouse. Nat Genet 21: 195-199, 1999.
-
(1999)
Nat Genet
, vol.21
, pp. 195-199
-
-
Vulpe, C.D.1
Kuo, Y.M.2
Murphy, T.L.3
Cowley, L.4
Askwith, C.5
Libina, N.6
Gitschier, J.7
Anderson, G.J.8
-
319
-
-
0037022588
-
Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis
-
Waheed A, Grubb JH, Zhou XY, Tomatsu S, Fleming RE, Costaldi ME, Britton RS, Bacon BR, and Sly WS. Regulation of transferrin-mediated iron uptake by HFE, the protein defective in hereditary hemochromatosis. Proc Natl Acad Sci U S A 99: 3117-3122, 2002.
-
(2002)
Proc Natl Acad Sci U S A
, vol.99
, pp. 3117-3122
-
-
Waheed, A.1
Grubb, J.H.2
Zhou, X.Y.3
Tomatsu, S.4
Fleming, R.E.5
Costaldi, M.E.6
Britton, R.S.7
Bacon, B.R.8
Sly, W.S.9
-
320
-
-
0033574075
-
Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum
-
Waheed A, Parkkila S, Saarnio J, Fleming RE, Zhou XY, Tomatsu S, Britton RS, Bacon BR and Sly WS. Association of HFE protein with transferrin receptor in crypt enterocytes of human duodenum. Proc Natl Acad Sci U S A 96: 1579-1584, 1999.
-
(1999)
Proc Natl Acad Sci U S A
, vol.96
, pp. 1579-1584
-
-
Waheed, A.1
Parkkila, S.2
Saarnio, J.3
Fleming, R.E.4
Zhou, X.Y.5
Tomatsu, S.6
Britton, R.S.7
Bacon, B.R.8
Sly, W.S.9
-
321
-
-
0030732164
-
Hereditary hemochromatosis: Effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells
-
Waheed A, Parkkila S, Zhou XY, Tomatsu S, Tsuchihashi Z, Feder JN, Schatzman RC, Britton RS, Bacon BR, and Sly WS. Hereditary hemochromatosis: effects of C282Y and H63D mutations on association with beta2-microglobulin, intracellular processing, and cell surface expression of the HFE protein in COS-7 cells. Proc Natl Acad Sci U S A 94: 12384-12389, 1997.
-
(1997)
Proc Natl Acad Sci U S A
, vol.94
, pp. 12384-12389
-
-
Waheed, A.1
Parkkila, S.2
Zhou, X.Y.3
Tomatsu, S.4
Tsuchihashi, Z.5
Feder, J.N.6
Schatzman, R.C.7
Britton, R.S.8
Bacon, B.R.9
Sly, W.S.10
-
322
-
-
33845865301
-
Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA
-
Walden WE, Selezneva AI, Dupuy J, Volbeda A, Fontecilla-Camps JC, Theil EC, and Volz K. Structure of dual function iron regulatory protein 1 complexed with ferritin IRE-RNA. Science 314: 1903-1908, 2006.
-
(2006)
Science
, vol.314
, pp. 1903-1908
-
-
Walden, W.E.1
Selezneva, A.I.2
Dupuy, J.3
Volbeda, A.4
Fontecilla-Camps, J.C.5
Theil, E.C.6
Volz, K.7
-
323
-
-
21044434748
-
-
Wallace DF, Summerville L, Lusby PE, and Subramaniam VN. Gut 54: 980-986, 2005.
-
(2005)
Gut
, vol.54
, pp. 980-986
-
-
Wallace, D.F.1
Summerville, L.2
Lusby, P.E.3
Subramaniam, V.N.4
-
324
-
-
0035040222
-
Transferrin is an insulin-like growth factor-binding protein-3 binding protein
-
Weinzimer SA, Gibson TB, Collett-Solberg PF, Khare A, Liu B, and Cohen P. Transferrin is an insulin-like growth factor-binding protein-3 binding protein. J Clin Endocrinol Metab 86: 1806-1813, 2001.
-
(2001)
J Clin Endocrinol Metab
, vol.86
, pp. 1806-1813
-
-
Weinzimer, S.A.1
Gibson, T.B.2
Collett-Solberg, P.F.3
Khare, A.4
Liu, B.5
Cohen, P.6
-
325
-
-
31444444162
-
Integration of oxygen signaling at the consensus HRE
-
Wenger RH, Stiehl DP, and Camenisch G. Integration of oxygen signaling at the consensus HRE. Sci STKE 2005: re12, 2005.
-
(2005)
Sci STKE
, vol.2005
-
-
Wenger, R.H.1
Stiehl, D.P.2
Camenisch, G.3
-
326
-
-
0034623930
-
Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE
-
West AP Jr, Bennett MJ, Sellers VM, Andrews NC, Enns CA, and Bjorkman PJ. Comparison of the interactions of transferrin receptor and transferrin receptor 2 with transferrin and the hereditary hemochromatosis protein HFE. J Biol Chem 275: 38135-38138, 2000.
-
(2000)
J Biol Chem
, vol.275
, pp. 38135-38138
-
-
West Jr, A.P.1
Bennett, M.J.2
Sellers, V.M.3
Andrews, N.C.4
Enns, C.A.5
Bjorkman, P.J.6
-
327
-
-
0033054177
-
The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis
-
Wong A, Yang J, Cavadini P, Gellera C, Lonnerdal B, Taroni F, and Cortopassi G. The Friedreich's ataxia mutation confers cellular sensitivity to oxidant stress which is rescued by chelators of iron and calcium and inhibitors of apoptosis. Hum Mol Genet 8: 425-430, 1999.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 425-430
-
-
Wong, A.1
Yang, J.2
Cavadini, P.3
Gellera, C.4
Lonnerdal, B.5
Taroni, F.6
Cortopassi, G.7
-
328
-
-
0021984206
-
Assignment of human ferritin genes to chromosomes 11 and 19q13.3 - 19qter
-
Worwood M, Brook JD, Cragg SJ, Hellkuhl B, Jones BM, Perera P, Roberts SH, and Shaw DJ. Assignment of human ferritin genes to chromosomes 11 and 19q13.3 - 19qter. Hum Genet 69: 371-374, 1985.
-
(1985)
Hum Genet
, vol.69
, pp. 371-374
-
-
Worwood, M.1
Brook, J.D.2
Cragg, S.J.3
Hellkuhl, B.4
Jones, B.M.5
Perera, P.6
Roberts, S.H.7
Shaw, D.J.8
-
329
-
-
0017065135
-
The purification and properties of ferritin from human serum
-
Worwood M, Dawkins S, Wagstaff M, and Jacobs A. The purification and properties of ferritin from human serum. Biochem J 157: 97-103, 1976.
-
(1976)
Biochem J
, vol.157
, pp. 97-103
-
-
Worwood, M.1
Dawkins, S.2
Wagstaff, M.3
Jacobs, A.4
-
330
-
-
33751175421
-
Interleukin-6 induces hepcidin expression through STAT3
-
Wrighting DM and Andrews NC. Interleukin-6 induces hepcidin expression through STAT3. Blood 108: 3204-3209, 2006.
-
(2006)
Blood
, vol.108
, pp. 3204-3209
-
-
Wrighting, D.M.1
Andrews, N.C.2
-
331
-
-
0029759283
-
Redox regulation of AP-1: A link between transcription factor signaling and DNA repair
-
Xanthoudakis S and Curran T. Redox regulation of AP-1: a link between transcription factor signaling and DNA repair. Adv Exp Med Biol 387: 69-75, 1996.
-
(1996)
Adv Exp Med Biol
, vol.387
, pp. 69-75
-
-
Xanthoudakis, S.1
Curran, T.2
-
332
-
-
1842504248
-
Aceruloplasminemia: An inherited neurodegenerative disease with impairment of iron homeostasis
-
Xu X, Pin S, Gathinji M, Fuchs R, and Harris ZL. Aceruloplasminemia: an inherited neurodegenerative disease with impairment of iron homeostasis. Ann N Y Acad Sci 1012: 299-305, 2004.
-
(2004)
Ann N Y Acad Sci
, vol.1012
, pp. 299-305
-
-
Xu, X.1
Pin, S.2
Gathinji, M.3
Fuchs, R.4
Harris, Z.L.5
-
333
-
-
33745070550
-
Involvement of endoplasmic reticulum stress on the cell death induced by 6-hydroxydopamine in human neuroblastoma SH-SY5Y cells
-
Yamamuro A, Yoshioka Y, Ogita K, and Maeda S. Involvement of endoplasmic reticulum stress on the cell death induced by 6-hydroxydopamine in human neuroblastoma SH-SY5Y cells. Neurochem Res 31: 657-664, 2006.
-
(2006)
Neurochem Res
, vol.31
, pp. 657-664
-
-
Yamamuro, A.1
Yoshioka, Y.2
Ogita, K.3
Maeda, S.4
-
334
-
-
0141989227
-
Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2
-
Yamanaka K, Ishikawa H, Megumi Y, Tokunaga F, Kanie M, Rouault TA, Morishima I, Minato N, Ishimori K, and Iwai K. Identification of the ubiquitin-protein ligase that recognizes oxidized IRP2. Nat Cell Biol 5: 336-340, 2003.
-
(2003)
Nat Cell Biol
, vol.5
, pp. 336-340
-
-
Yamanaka, K.1
Ishikawa, H.2
Megumi, Y.3
Tokunaga, F.4
Kanie, M.5
Rouault, T.A.6
Morishima, I.7
Minato, N.8
Ishimori, K.9
Iwai, K.10
-
335
-
-
0037131264
-
Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation
-
Yang F, Liu XB, Quinones M, Melby PC, Ghio A, and Haile DJ. Regulation of reticuloendothelial iron transporter MTP1 (Slc11a3) by inflammation. J Biol Chem 277: 39786-39791, 2002.
-
(2002)
J Biol Chem
, vol.277
, pp. 39786-39791
-
-
Yang, F.1
Liu, X.B.2
Quinones, M.3
Melby, P.C.4
Ghio, A.5
Haile, D.J.6
-
336
-
-
0021223826
-
Human transferrin: CDNA characterization and chromosomal localization
-
Yang F, Lum JB, McGill JR, Moore CM, Naylor SL, van Bragt PH, Baldwin WD, and Bowman BH. Human transferrin: cDNA characterization and chromosomal localization. Proc Natl Acad Sci U S A 81: 2752-2756, 1984.
-
(1984)
Proc Natl Acad Sci U S A
, vol.81
, pp. 2752-2756
-
-
Yang, F.1
Lum, J.B.2
McGill, J.R.3
Moore, C.M.4
Naylor, S.L.5
van Bragt, P.H.6
Baldwin, W.D.7
Bowman, B.H.8
-
337
-
-
2942744572
-
Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis
-
Yoon T and Cowan JA. Frataxin-mediated iron delivery to ferrochelatase in the final step of heme biosynthesis. J Biol Chem 279: 25943-25946, 2004.
-
(2004)
J Biol Chem
, vol.279
, pp. 25943-25946
-
-
Yoon, T.1
Cowan, J.A.2
-
338
-
-
4544388003
-
Evidence for the presence of ferritin in plant mitochondria
-
Zancani M, Peresson C, Biroccio A, Federici G, Urbani A, Murgia I, Soave C, Micali F, Vianello A, and Macri F. Evidence for the presence of ferritin in plant mitochondria. Eur J Biochem 271: 3657-3664, 2004.
-
(2004)
Eur J Biochem
, vol.271
, pp. 3657-3664
-
-
Zancani, M.1
Peresson, C.2
Biroccio, A.3
Federici, G.4
Urbani, A.5
Murgia, I.6
Soave, C.7
Micali, F.8
Vianello, A.9
Macri, F.10
-
339
-
-
3042793602
-
The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging
-
Zecca L, Stroppolo A, Gatti A, Tampellini D, Toscani M, Gallorini M, Giaveri G, Arosio P, Santambrogio P, Fariello RG, Karatekin E, Kleinman MH, Turro N, Hornykiewicz O, and Zucca FA. The role of iron and copper molecules in the neuronal vulnerability of locus coeruleus and substantia nigra during aging. Proc Natl Acad Sci U S A 101: 9843-9848, 2004.
-
(2004)
Proc Natl Acad Sci U S A
, vol.101
, pp. 9843-9848
-
-
Zecca, L.1
Stroppolo, A.2
Gatti, A.3
Tampellini, D.4
Toscani, M.5
Gallorini, M.6
Giaveri, G.7
Arosio, P.8
Santambrogio, P.9
Fariello, R.G.10
Karatekin, E.11
Kleinman, M.H.12
Turro, N.13
Hornykiewicz, O.14
Zucca, F.A.15
-
340
-
-
8344265251
-
Iron, brain ageing and neurodegenerative disorders
-
Zecca L, Youdim MB, Riederer P, Connor JR, and Crichton RR. Iron, brain ageing and neurodegenerative disorders. Nat Rev Neurosci 5: 863-873, 2004.
-
(2004)
Nat Rev Neurosci
, vol.5
, pp. 863-873
-
-
Zecca, L.1
Youdim, M.B.2
Riederer, P.3
Connor, J.R.4
Crichton, R.R.5
-
341
-
-
21244448393
-
Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis
-
Zhang Y, Lyver ER, Knight SA, Lesuisse E, and Dancis A. Frataxin and mitochondrial carrier proteins, Mrs3p and Mrs4p, cooperate in providing iron for heme synthesis. J Biol Chem 280: 19794-19807, 2005.
-
(2005)
J Biol Chem
, vol.280
, pp. 19794-19807
-
-
Zhang, Y.1
Lyver, E.R.2
Knight, S.A.3
Lesuisse, E.4
Dancis, A.5
-
342
-
-
0001376313
-
HFE gene knockout produces mouse model of hereditary hemochromatosis
-
Zhou XY, Tomatsu S, Fleming RE, Parkkila S, Waheed A, Jiang J, Fei Y, Brunt EM, Ruddy DA, Prass CE, Schatzman RC, O'Neill R, Britton RS, Bacon BR, and Sly WS. HFE gene knockout produces mouse model of hereditary hemochromatosis. Proc Natl Acad Sci U S A 95: 2492-2497, 1998.
-
(1998)
Proc Natl Acad Sci U S A
, vol.95
, pp. 2492-2497
-
-
Zhou, X.Y.1
Tomatsu, S.2
Fleming, R.E.3
Parkkila, S.4
Waheed, A.5
Jiang, J.6
Fei, Y.7
Brunt, E.M.8
Ruddy, D.A.9
Prass, C.E.10
Schatzman, R.C.11
O'Neill, R.12
Britton, R.S.13
Bacon, B.R.14
Sly, W.S.15
|