An iron-responsive element type II in the 5′-untranslated region of the Alzheimer's amyloid precursor protein transcript

Journal of Biological Chemistry

Volumn 277, Issue 47, 2002, Pages 45518-45528

  Rogers, Jack T ^a,d   Randall, Jeffrey D ^a,d   Cahill, Catherine M ^b   Eder, Paul S ^c   Huang, Xudong ^a   Gunshin, Hiromi ^a   Leiter, Lorene ^a   McPhee, Jay ^a   Sarang, Satinder S ^a   Utsuki, Tada ^c   Greig, Nigel H ^c   Lahiri, Debomoy K ^d   Tanzi, Rudolph E ^a   Bush, Ashley I ^a   Giordano, Tony ^c   Gullans, Steve R ^a  

^a HARVARD MEDICAL SCHOOL   (United States)

^b MASSACHUSETTS GENERAL HOSPITAL   (United States)

^c Message Pharmaceuticals Inc   (United States)

^d INDIANA UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

CELLS; CHELATION; IRON; METABOLISM; PROTEINS; RNA;

IRON CHELATION;

BIOCHEMISTRY;

AMYLOID PRECURSOR PROTEIN; CHLORAMPHENICOL ACETYLTRANSFERASE; CLIOQUINOL; COPPER; DEFEROXAMINE; IRON; IRON REGULATORY FACTOR; LUCIFERASE; RED FLUORESCENT PROTEIN; RNA; ZINC;

ALZHEIMER DISEASE; ARTICLE; ASSAY; CELL LYSATE; CONTROLLED STUDY; DRUG TARGETING; GEL MOBILITY SHIFT ASSAY; GENE MAPPING; HOMEOSTASIS; HUMAN; HUMAN CELL; IRON CHELATION; IRON RESPONSIVE ELEMENT; IRON TRANSPORT; PRIORITY JOURNAL; PROTEIN LOCALIZATION; PROTEIN METABOLISM; PROTEIN TRANSPORT; REPORTER GENE; RNA STRUCTURE; RNA TRANSLATION;

5' UNTRANSLATED REGIONS; ALZHEIMER DISEASE; AMYLOID BETA-PROTEIN PRECURSOR; ANIMALS; BASE SEQUENCE; CALCIUM; CLIOQUINOL; DEFEROXAMINE; ENHANCER ELEMENTS (GENETICS); GENE EXPRESSION REGULATION; GENES, REPORTER; HUMANS; INTERLEUKIN-1; IRON; IRON CHELATING AGENTS; MAGNESIUM; MICE; MOLECULAR SEQUENCE DATA; NUCLEIC ACID CONFORMATION; PROTEIN BIOSYNTHESIS; RESPONSE ELEMENTS; RNA, MESSENGER; TUMOR CELLS, CULTURED;

EID: 0347928847     PISSN: 00219258     EISSN: None     Source Type: Journal    
DOI: 10.1074/jbc.M207435200     Document Type: Article

References (50)

1. Selkoe, D. J. (1996) J. Biol. Chem. 271, 18295-18298
2. Mucke, L., Masliah, E., Yu, G. Q., Mallory, M., Rockenstein, E. M., Tatsuno, G., Hu, K., Kholodenko, D., Johnson-Wood, K., and McConlogue, L. (2000) J. Neurosci. 20, 4050-4058
3. Multhaup, G., Schlicksupp, A., Hesse, L., Beher, D., Ruppert, T., Masters, C., and Beyreuther, K. (1996) Science 271, 1406-1409
4. Bush, A., Pettingell, W. H., Multhaup, G., Paradis, D., Vonsattel, J. P., Gusella, J. F., Beyreuther, K., Masters, C. L., and Tanzi, R. E. (1994) Science 265, 1464-1467
5. Tanzi, R. E., Gusella, J. F., Watkins, P. C., Bruns, G. A., St George-Hyslop, P., Van Keuren, M. L., Patterson, D., Pagan, S., Kurnit, D. M., and Neve, R. L. (1987) Science 235, 880-884
6. Kang, J., Lemaire, H. G., Unterbeck, A., Salbaum, J. M., Masters, C. L., Grzeschik, K. H., Multhaup, G., Beyreuther, K., and Muller-Hill, B. (1987) Nature 325, 733-736
7. Saitoh, T., Sundsmo, M., Roch, J. M., Kimura, N., Cole, G., Schubert, D., Oltersdorf, T., and Schenk, D. B. (1989) Cell 58, 615-622
8. van Leeuwen, F., de Kleijn, D. P. V., van den Hurk, H. H., Neubauer, A., Sonnemans, M. A. F., Sluijs, J. A., Koycu, S., Ramdjielal, R. D. J., Salehi, A., Martens, G. J. M., Grosveld, F. G., Burbach, P. H., and Hol, E. M. (1998) Science 279, 242-247
9. Rogers, J. T., Leiter, L. M., McPhee, J., Cahill, C. M., Zhan, S. S., Potter, H., and Nilsson, L. N. (1999) J. Biol. Chem. 274, 6421-6431
10. Komori, N., Kittel, A., Kang, D., Shackelford, D., Masliah, E., Zivin, J. A., and Saitoh, T. (1997) Brain Res. Mol. Brain Res. 49, 103-112
11. Mbella, E. G., Bertrand, S., Huez, G., and Octave, J. N. (2000) Mol. Cell. Biol. 20, 4572-4579
12. Eisenstein, R., and Theil, E. (2000) J. Biol. Chem. 275, 40659-40662
13. Theil, E. (1987) Ann. Rev. Biochem. 56, 289-315
14. Rogers, J. (1992) (Lauffer R, ed), pp. 77-104, CRC Press, Inc., Boca Raton, FL
15. Rogers, J. T., and Munro, H. N. (1987) Proc. Natl. Acad. Sci. U. S. A. 84, 2277-2281
16. Thomson, A. M., Rogers, J. T., and Leedman, P. J. (2000) J. Biol. Chem. 275, 31609-31615
17. Schalinske, K., Blemings, K., Steffen, D. W., Chen, O. S., and Eisenstein, R. S. (1997) Proc. Natl. Acad. Sci. U. S. A. 94, 10681-10686
18. LaVaute, T., Smith, S., Cooperman, S., Iwai, K., Land, W., Meyron-Holtz, E., Drake, S. K., Miller, G., Abu-Asab, M., Tsokos, M., Switzer, R., Grinberg, A., Love, P., Tresser, N., and Rouault, T. A. (2001) Nat. Genet. 27, 209-214
19. Kim, H.-Y., Klausner, R. D., and Rouault, T. A. (1994) J. Biol. Chem. 270, 4983-4986
20. Thomson, A. M., Rogers, J. T., and Leedman, P. J. (1999) Int. J. Biochem. Cell Biol. 31, 1139-1152
21. Leedman, P., Stein, A. R., Chin, W. W., and Rogers, J. T. (1996) J. Biol. Chem. 271, 12017-12023
22. Iwai, K., Drake, S. K., Wehr, N. B., Weissman, A. M., LaVaute, T., Minato, N., Klausner, R. D., Levine, R. L., and Rouault, T. A. (1998) Proc. Natl. Acad. Sci. U. S. A. 95, 4924-4928
23. Sampietro, M., Caputo, L., Casatta, A., Meregalli, M., Pellagatti, A., Tagliabue, J., Annoni, G., and Vergani, C. (2001) Neurobiol. Aging 22, 563-568
24. Bartzokis, G., Sultzer, D., Cummings, J., Holt, L. E., Hance, D. B., Henderson, V. W., and Mintz, J. (2000) Arch. Gen. Psychiatry 57, 47-53
25. Lovell, M. A., Robertson, J. D., Teesdale, W. J., Campbell, J. L., and Markesbery, W. R. (1998) J. Neurol. Sci. 158, 47-52
26. Connor, J. R., Boeshore, K. L., Benkovic, S. A., and Menzies, S. L. (1994) J. Neurosci. Res. 37, 461-465
27. Pinero, D. J., Hu, J., and Connor, J. R. (2000) Cell. Mol. Biol. (Noisy-le-grand) 46, 761-776
28. Robinson, S., Noone, D. F., Kril, J., and Haliday, G. M. (1995) Alzheimer's Res. 1, 191-193
29. Bodovitz, S., Falduto, M. T., Frail, D. E., and Klein, W. L. (1995) J. Neurochem. 64, 307-315
30. Buxbaum, J. D., Choi, E. K., Luo, Y., Lilliehook, C., Crowley, A. C., Merriam, D. E., and Wasco, W. (1998) Nat. Med. 4, 1177-1181
31. Buxbaum, J., Oishi, M., Chen, H. I., Pinkas-Kramarski, R., Jaffe, E. A., Gandy, S. E., and Geengard, P. (1992) Proc. Natl. Acad. Sci. U. S. A. 89, 10075-10078
32. Mullner, E., Neupert, B., and Kuhn, L. C. (1989) Cell 58, 373-382
33. Thomson, A. M., Rogers, J. T., Walker, C., E., Staton, J. M., and Leedman, P. J. (1999) Biotechniques 27, 1032-1039
34. Selkoe, D. J., Berman Polisny, M., Joachim, C. L., Vickers, E. A., Lee, G., Fritz, L. C., and Oltersdorf, T. (1988) Proc. Natl. Acad. Sci. U. S. A., 85, 7341-7345
35. Cherny, R., Atwood, C. S., Xilinas, M. E., Gray, D. N., Jones, W. D., McLean, C. A., Barnham, K. J., Volitakis, I., Fraser, F. W., Kim, Y., Huang, X., Goldstein, L. E., Moir, R. D., Lim, J. T., Beyreuther, K., Zheng, H., Tanzi, R. E., Masters, C. L., and Bush A. I. (2001) Neuron 30, 641-642
36. Rogers, J. T. (1996) Blood 87, 2525-2537
37. Zuker, M. (1989) Science 244, 48-52
38. Eckblom, J. (2001) Drug Discov. Today 6, 1259-1260
39. Toth, I., Yuan, L., Rogers, J. T., Boyce, H., and Bridges, K. R (1999) J. Biol. Chem. 274, 4467-4473
40. Gray, N., Quick, S., Goossen, B., Constable, A., Hirling, H., Kuhn, L. C., and Hentze, M. (1993) Eur. J. Biochem. 218, 657-667
41. Cox, L. A., and Adrian, G. S. (1993) Biochemistry 32, 4738-4745
42. Feng, Y., Zhang, F., Lokey, L. K., Chastain, J. L., Lakkis, L., Eberhart, D., and Warren, S. T. (1995) Science 268, 731-734
43. Cox, T. C., Bawden, M. J., Martin, A., and May, B. K. (1991) EMBO J. 10, 1891-1902
44. Donovan, A., Brownlie, A., Zhou, Y., Shepard, J., Pratt, S. J., Moynihan, J., Paw, B. H., Drejer, A., Barut, B., Zapata, A., Law, T. C., Brugnara, C., Lux, S. E., Pinkus, G. S., Pinkus, J. L., Kingsley, P. D., Palis, J., Fleming, M. D., Andrews, N. C., and Zon, L. I. (2000) Nature 403, 776-781
45. McKie, A. T., Marciani, P., Rolfs, A., Brennan, K., Wehr, K., Barrow, D., Miret, S., Bomford, A., Peters, T. J., Farzaneh, F., Hediger, M. A., Hentze, M. W., and Simpson, R. J. (2000) Mol. Cell 5, 299-309
46. Tanzi, R. E., and Hyman, B. T. (1991) Nature 350, 564
47. Zubenko, G., Farr, J., Stiffler, S., Hughes, H. B., and Kaplan, B. B. (1992) J. Neuropathol. Exp. Neurol. 51, 459-463
48. Wasco, W., Gurubhagavatula, S., Paradis, M. D., Romano, D. M., Sisodia, S. S., Hyman, B. T., Neve, R. L., and Tanzi, R. E. (1993) Nat. Genet. 5, 95-100
49. von Koch, C. S., Zheng, H., Chen, H., Trumbauer, M., Thinakaran, G., van der Ploeg, L. H., Price, D. L., and Sisodia, S. S. (1997) Neurobiol. Aging 18, 661-669
50. Crapper McLachlan, D., Dalton, A. J., Kruck, T. P. A., Bell, M. Y., Smith, W. L., Kalow, W., and Andrews, D. F. (1991) Lancet 337, 1304-1308