Disruption of ceruloplasmin and hephaestin in mice causes retinal iron overload and retinal degeneration with features of age-related macular degeneration

Proceedings of the National Academy of Sciences of the United States of America

Volumn 101, Issue 38, 2004, Pages 13850-13855

  Hahn, Paul ^a   Qian, Ying ^a   Dentchev, Tzvete ^a   Chen, Lin ^a   Beard, John ^b   Harris, Zena Leah ^c   Dunaief, Joshua L ^a  

^a UNIVERSITY OF PENNSYLVANIA   (United States)

^b PENNSYLVANIA STATE UNIVERSITY   (United States)

^c JOHNS HOPKINS UNIVERSITY SCHOOL OF MEDICINE   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

ANGIOGENESIS INHIBITOR; CERULOPLASMIN; CHELATING AGENT; FERRITIN; HEPHAESTATIN; IRON; UNCLASSIFIED DRUG;

ACERULOPLASMINEMIA; ALZHEIMER DISEASE; ANIMAL CELL; ANIMAL TISSUE; ARTICLE; BLOOD BRAIN BARRIER; GLIA CELL; HUMAN; IRON BALANCE; IRON OVERLOAD; MOUSE; MUELLER CELL; NERVE DEGENERATION; NONHUMAN; PHOTORECEPTOR; PIGMENT EPITHELIUM; PRIORITY JOURNAL; PROTEIN LOCALIZATION; RETINA DEGENERATION; RETINA DISEASE; RETINA MACULA AGE RELATED DEGENERATION; RETINA NEOVASCULARIZATION;

ANIMALS; CERULOPLASMIN; CROSSES, GENETIC; MACULAR DEGENERATION; MEMBRANE PROTEINS; MICE; MICE, INBRED C57BL; MICE, KNOCKOUT; RETINAL DEGENERATION; REVERSE TRANSCRIPTASE POLYMERASE CHAIN REACTION; VITAMIN A;

ANIMALIA;

EID: 4644293303     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.0405146101     Document Type: Article

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