Molecular control of vertebrate iron metabolism: mRNA-based regulatory circuits operated by iron, nitric oxide, and oxidative stress

Proceedings of the National Academy of Sciences of the United States of America

Volumn 93, Issue 16, 1996, Pages 8175-8182

  Hentze, Matthias W ^a   Kühn, Lukas C ^b  

^a EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^b SWISS INST FOR EXP CANCER RESEARCH   (Switzerland)

Author keywords

[No Author keywords available]

Indexed keywords

5 AMINOLEVULINATE SYNTHASE; ACONITATE HYDRATASE; FERRITIN; IRON; IRON REGULATORY FACTOR; IRON SULFUR PROTEIN; MESSENGER RNA; NITRIC OXIDE; PROTOPORPHYRIN; RNA BINDING PROTEIN; SUCCINATE DEHYDROGENASE; TRANSFERRIN RECEPTOR;

CELL METABOLISM; GENETIC CONSERVATION; HUMAN; IRON METABOLISM; IRON RESPONSIVE ELEMENT; NONHUMAN; NUCLEOTIDE SEQUENCE; OXIDATIVE STRESS; PHYLOGENY; PRIORITY JOURNAL; PROTEIN DEGRADATION; PROTEIN PROCESSING; PROTEIN RNA BINDING; PROTEIN SYNTHESIS; REVIEW; RNA TRANSLATION; TRANSCRIPTION REGULATION; TRANSLATION REGULATION;

ANIMALS; BASE SEQUENCE; BINDING SITES; FERRITINS; GENE EXPRESSION REGULATION; HOMEOSTASIS; IRON; IRON REGULATORY PROTEIN 1; IRON REGULATORY PROTEIN 2; IRON-REGULATORY PROTEINS; IRON-SULFUR PROTEINS; MITOCHONDRIA; MOLECULAR SEQUENCE DATA; NITRIC OXIDE; NUCLEIC ACID CONFORMATION; OXIDATION-REDUCTION; PROTEIN BIOSYNTHESIS; RECEPTORS, TRANSFERRIN; REGULATORY SEQUENCES, NUCLEIC ACID; RNA PROCESSING, POST-TRANSCRIPTIONAL; RNA, MESSENGER; RNA-BINDING PROTEINS;

VERTEBRATA;

EID: 0029758487     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.93.16.8175     Document Type: Review

References (151)

1. Aziz, N. & Munro, H. N. (1987) Proc. Natl. Acad. Sci. USA 84, 8478-8482.
2. Leibold, E. A. & Munro, H. N. (1987) J. Biol. Chem. 262, 7335-7341.
3. Hentze, M. W., Rouault, T. A., Caughman, S. W., Danois, A., Harford, J. B. & Klausner, R. D. (1987) Proc. Natl. Acad. Sci. USA 84, 6730-6734.
4. Hentze, M. W., Caughman, S. W., Rouault, T. A., Barriocanal, J. G., Dancis, A., Harford, J. B. & Klausner, R. D. (1987) Science 238, 1570-1572.
5. Walden, W. E., Daniels-McQueen, S., Brown, P. H., Gaffield, L., Russell, D. A., Bielser, D., Bailey, L. C. & Thach, R, E. (1988) Proc. Natl. Acad. Sci. USA 85, 9503-9507.
6. Brown, P. H., Daniels-McQueen, S., Walden, W. E., Patino, M. M., Gaffield, L., Bielser, D. & Thach, R. E. (1989) J. Biol. Chem, 264, 13383-13386.
7. Casey, J. L., Hentze, M. W., Koeller, D. M., Caughman, S. W., Rouault, T. A., Klausner, R. D. & Harford, J. B. (1988) Science 240, 924-928.
8. Owen, D. & Kühn, L. C. (1987) EMBO J. 6, 1287-1293.
9. Müllner, E. W. & Kühn, L. C. (1988) Cell 53, 815-825.
10. Casey, J. L., Di Jeso, B., Rao, K., Klausner, R. D. & Harford, J. B. (1988) Proc. Natl. Acad, Sci. USA 85, 1787-1791.
11. Müllner, E. W., Neupert, B. & Kühn, L. C. (1989) Cell 58, 373-382.
12. Koeller, D. M., Casey, J. L., Hentze, M. W., Gerhardt, E. M., Chan, L.-N., Klausner, R. D. & Harford, J. B. (1989) Proc. Natl. Acad. Sci. USA 86, 3574-3578.
13. May, B. K., Bhasker, C. R., Bawden, M. J. & Cox, T. C. (1990) Mol. Biol. Med. 7, 405-421.
14. Cox, T. C., Bawden, M. J., Martin, A. & May, B. K. (1991) EMBO J. 10, 1891-1902.
15. Dandekar, T., Stripecke, R., Gray, N. K., Goossen, B., Constable, A., Johansson, H. E. & Hentze, M. W. (1991) EMBO J. 10, 1903-1909.
16. Zheng, L., Kennedy, M. C., Blondin, G. A., Beinert, H. & Zalkin, H. (1992) Arch. Biochem. Biophys. 299, 356-360.
17. Kohler, S. A., Henderson, B. R. & Kühn, L. C. (1995) J. Biol. Chem. 270, 30781-30786.
18. Gray, N. K., Pantopoulos, K., Dandekar, T., Ackrell, B. A. C. & Hentze, M. W. (1996) Proc. Natl. Acad. Sci. USA 93, 4925-4930.
19. Melefors, O., Goossen, B., Johansson, H. E., Stripecke, R., Gray, N. K. & Hentze, M. W. (1993) J. Biol. Chem. 268, 5974-5978.
20. Bhasker, C. R., Burgiel, G., Neupert, B., Emery-Goodman, A., Kühn, L. C. & May, B. K. (1993) J. Biol. Chem. 268, 12699-12705.
21. Gray, N. K. & Hentze, M. W. (1994) EMBO J. 13, 3882-3891.
22. Von Darl, M., Harrison, P. M. & Bottke, W. (1994) Eur. J. Biochem. 222, 353-366.
23. Dunkov, B. C., Zhang, D., Choumarov, K., Winzerling, J. J. & Law, J. H. (1995) Arch. Insect Biochem. Physiol. 29, 293-307.
24. Rothenberger, S., Müllner, E. W. & Kühn, L. C. (1990) Nucleic Acids Res. 18, 1175-1179.
25. Oliveira, C. C., Goossen, B., Zanchin, N. I. T., McCarthy, J. E. G., Hentze, M. W. & Stripecke, R. (1993) Nucleic Acids Res. 21, 5316-5322.
26. Cox, L. A. & Adrian, G. S. (1993) Biochemistry 32, 4738-4745.
27. Cox, L. A., Kennedy, M. C. & Adrian, G. S. (1995) Biochem. Biophys. Res. Commun. 212, 925-932.
28. Henderson, B. R., Menotti, E., Bonnard, C. & Kühn, L. C. (1994) J. Biol. Chem. 269, 17481-17489.
29. Hentze. M. W., Caughman, S. W., Casey, J. L., Koeller, D. M., Rouault, T. A., Harford, J. B. & Klausner, R. D. (1988) Gene 72, 201-208.
30. Haile, D. J., Hentze, M. W., Rouault, T. A., Harford, J. B. & Klausner, R. D. (1989) Mol. Cell. Biol. 9, 5055-5061.
31. Barton, H. A., Eisenstein, R. S., Bomford, A. & Munro, H. N. (1990) J. Biol. Chem. 265, 7000-7008.
32. Jaffrey, S. R., Haile, D. J., Klausner, R. D. & Harford, J. B. (1993) Nucleic Acids Res. 21, 4627-4631.
33. Leibold, E. A., Laudano, A. & Yu, Y. (1990)Nucleic Acids Res. 18, 1819-1824.
34. Bettany, A. J. E., Eisenstein, R. S. & Munro, H. N. (1992) J. Biol. Chem. 267, 16531-16537.
35. Beaumont, C., Leneuve, P., Devaux, I., Scoazec, J.-Y., Berthier, M., Loiseau, M-N., Grandchamp, B. & Bonneau, D. (1995) Nat. Genet. 11, 444-446.
36. Henderson, B. R., Menotti, E. & Kühn, L. C. (1996) J. Biol. Chem. 271, 4900-4908.
37. Sierzputowska-Gracz, H., McKenzie, R. A. & Theil, E. C. (1995) Nucleic Acids Res. 23, 146-153.
38. Dandekar, T. & Hentze, M. W. (1995) Trends Genet. 11, 45-50.
39. Drysdale, J. W. & Munro, H. N. (1966) J. Biol. Chem. 241, 3630-3637.
40. Zähringer, J., Baliga, B. S. & Munro, H. N. (1976) Proc. Natl. Acad. Sci. USA 73, 857-861.
41. Shull, G. E. & Theil, E. C. (1982) J. Biol. Chem. 257, 14187-14191.
42. Shull, G. E. & Theil, E. C. (1983) J. Biol. Chem. 258, 7921-7923.
43. Leibold, E. A. & Munro, H. N. (1988) Proc. Natl. Acad. Sci. USA 85, 2171-2175.
44. Rouault, T. A., Hentze, M. W., Caughman, S. W., Harford, J. B. & Klausner, R. D. (1988) Science 241, 1207-1210.
45. Caughman, S. W., Hentze, M. W., Rouault, T. A., Harford, J. B. & Klausner, R. D. (1988) J. Biol. Chem. 263, 19048-19052.
46. Walden, W. E., Patino, M. M. & Gaffield, L. (1989) J. Biol. Chem. 264, 13765-13769.
47. Gray, N. K., Quick, S., Goossen, B., Constable, A., Hirling, H., Kühn, L. C. & Hentze, M. W. (1993) Eur. J. Biochem. 218, 657-667.
48. Kim, H. Y., Klausner, R. D. & Rouault, T. A. (1995) J. Biol. Chem. 270, 4983-4986.
49. Dickey, L. F., Wang, Y.-H., Shull, G. E., Wortman III, I. A. & Theil, E. C. (1988) J. Biol. Chem. 263, 3071-3074.
50. Dix, D. J., Lin, P. N., McKenzie, A. R., Walden, W. E. & Theil, E. C. (1993) J. Mol. Biol. 231, 230-240.
51. White, K. & Munro, H. N. (1988) J. Biol. Chem. 263, 8938-8942.
52. Goossen, B. & Hentze, M. W. (1992) Mol. Cell. Biol. 12, 1959-1966.
53. Coulson, R. M. R. & Cleveland, D. W. (1993) Proc. Natl. Acad. Sci. USA 90, 7613-7617.
54. Goossen, B., Caughman, S. W., Harford, S. B., Klausner, R. D. & Hentze, M. W. (1990) EMBO J. 9, 4127-4133.
55. Stripecke, R., Oliveira, C. C., McCarthy, J. E. G. & Hentze, M. W. (1994) Mol. Cell. Biol. 14, 5898-5909.
56. Stripecke, R. & Hentze, M. W. (1992) Nucleic Acids Res. 20, 5555-5564.
57. Gray, N. K. & Hentze, M. W. (1994) Mol. Biol. Reports 19, 195-200.
58. Pelicci, P. G., Tabilio, A., Thomopoulos, P., Titeux, M., Vainchenker, W., Rochant, H. & Testa, U. (1982) FEBS Lett. 145, 350-354.
59. Ward, J. H., Kushner, J. P. & Kaplan, J. (1982) J. Biol. Chem. 257, 10317-10323.
60. Kühn, L. C., McClelland, A. & Ruddle, F. H. (1984) Cell 37, 95-103.
61. McClelland, A., Kühn, L. C. & Ruddle, F. H. (1984) Cell 39, 267-274.
62. Schneider, C., Owen, M. J., Banville, D. & Williams, J. G. (1984) Nature (London) 311, 675-678.
63. Rao, K. K., Shapiro, D., Mattia, E., Bridges, K. & Klausner, R. (1985) Mol. Cell. Biol. 5, 595-600.
64. Rao, K. K., Harford, J. B., Rouault, T., McClelland, A., Ruddle, F. H. & Klausner, R. D. (1986) Mol. Cell. Biol. 6, 236-240.
65. Roberts, K. P. & Griswold, M. D. (1990) Mol. Endocrinol. 4, 531-542.
66. Chan, L.-N. L., Grammatikakis, N., Banks, J. M. & Gerhardt, E. M. (1989) Nucleic Acids Res. 17, 3763-3771.
67. Horowitz, J. A. & Harford, J. B. (1992) New Biol. 4, 330-338.
68. Bertrand, E., Fromont Racine, M., Pictet, R. & Grange, T. (1993) Proc. Natl. Acad. Sci. USA 90, 3496-3500.
69. Casey, J. L., Koeller, D. M., Ramin, V. C., Klausner, R. D. & Harford, J. B. (1989) EMBO J. 8, 3693-3699.
70. Seiser, C., Posch, M., Thompson, N. & Kühn, L. C. (1995) J. Biol. Chem. 270, 29400-29406.
71. Binder, R., Horowitz, J. A., Basilion, J. P., Koeller, D. M., Klausner, R. D. & Harford, J. B. (1994) EMBO J. 13, 1969-1980.
72. Chen, C.-Y. A. & Shyu, A.-B. (1995) Trends Biochem. Sci. 20, 465-470.
73. Shyu, A. B., Belasco, J. G. & Greenberg, M. E. (1991) Genes Dev. 5, 221-231.
74. Decker, C. & Parker, R. (1993) Genes Dev. 7, 1632-1643.
75. Koeller, D. M., Horowitz, J. A., Casey, J. L., Klausner, R. D. & Harford, J. B. (1991) Proc. Natl. Acad. Sci. USA 88, 7778-7782.
76. Hentze, M. W., Rouault, T. A., Harford, J. B. & Klausner, R. D. (1989) Science 244, 357-359.
77. Müllner, E. W., Rothenberger, S., Müller, A. M. & Kühn, L. C. (1992) Eur. J. Biochem. 208, 597-605.
78. Henderson, B. R., Seiser, C. & Kühn. U.C. (1993) J. Biol. Chem. 268, 27327-27334.
79. Guo, B., Yu, Y. & Leibold, E. A. (1994) J. Biol. Chem. 269, 24252-24260.
80. Samaniego, F., Chin, J., Iwai, K., Rouault, T. A. & Klausner, R. D. (1994) J. Biol. Chem. 269, 30904-30910.
81. Patino, M. M. & Walden, W. E. (1992) J. Biol. Chem. 267, 19011-19016.
82. Testa, U., Kühn, L. C., Petrini, M., Quaranta, M. T., Pelosi, E. & Peschle, C. (1991) J. Biol. Chem. 266, 13925-13930.
83. Seiser, C., Teixeira, S. & Kühn, L. C. (1993) J. Biol. Chem. 268,13074-13080.
84. Cairo, G. & Pietrangelo, A. (1994) J. Biol. Chem. 269, 1-5.
85. Neupert, B., Thompson, N. A., Meyer. C. & Kühn, L. C. (1990) Nucleic Acids Res. 18, 51-55.
86. Rouault, T. A., Hentze, M. W., Haile, D. J., Harford, J. B. & Klausner, R. D. (1989) Proc. Natl. Acad. Sci. USA 86, 5768-5772.
87. Haile, D. J., Rouault, T. A., Harford, J. B., Kennedy, M. C., Blondin, G. A., Beinert, H. & Klausner, R. D. (1992) Proc. Natl. Acad. Sci. USA 89, 11735-11739.
88. Hirling, H., Henderson, B. R. & Kühn, L. C. (1994) EMBO J. 13, 453-461.
89. Yu, Y., Radisky, E. & Leibold, E. A. (1992) J. Biol. Chem. 267, 19005-19010.
90. Rouault, T. A., Tang, C. K., Kaptain, S., Burgess, W. H., Haile, D. J., Samaniego, F., McBride, O. W., Harford, J. B. & Klausner, R. D. (1990) Proc. Natl. Acad. Sci. USA 87, 7958-7962.
91. Philpott, C. C, Rouault, T. A. & Klausner, R. D. (1991) Nucleic Acids Res. 19, 6333.
92. Hirling, H., Emery-Goodman, A., Thompson, N., Neupert, B., Seiser, C. & Kühn, L. C. (1992) Nucleic Acids Res. 20, 33-39.
93. Hentze, M. W. & Argos, P. (1991) Nucleic Acids Res. 19, 1739-1740.
94. Rouault, T. A., Stout, C. D., Kaptain, S., Harford, J. B. & Klausner, R. D. (1991) Cell 64, 881-883.
95. Prodromou, C., Artymiuk, P. J. & Guest, J. R. (1992) Eur. J. Biochem. 204, 599-609.
96. Gruer, M. J. & Guest, J. R. (1994) Microbiology 140, 2531-2541.
97. Kennedy, M. C., Mende-Mueller, L., Blondin, G. A. & Beinert, H. (1992) Proc. Natl. Acad. Sci. USA 89, 11730-11734.
98. Haile, D. J., Rouault, T. A., Tang, C. K., Chin. J., Harford, J. B. & Klausner, R. D. (1992) Proc. Natl. Acad. Sci. USA 89, 7536-7540.
99. Kaptain, S., Downey, W. E., Tang, C., Philpott, C. C., Haile, D., Orloff, D. G., Harford, J. B., Rouault, T. A. & Klausner, R. D. (1991) Proc. Natl. Acad. Sci. USA 88, 10109-10113.
100. Constable, A., Quick, S., Gray, N. K. & Hentze, M. W. (1992) Proc. Natl. Acad. Sci. USA 89, 4554-4558.
101. Tang, C. K., Chin, J., Harford, J. B., Klausner, R. D. & Rouault, T. A. (1992) J. Biol. Chem. 267, 24466-24470.
102. Emery-Goodman, A., Hirling, H., Scarpellino, L., Henderson, B. & Kühn, L. C. (1993) Nucleic Acids Res. 21, 1457-1461.
103. Basilion, J. P., Kennedy, M. C, Beinert, H., Massinople, C. M., Klausner, R. D. & Rouault, T. A. (1994) Arch. Biochem. Biophys. 311, 517-522.
104. Pantopoulos, K., Gray, N. K. & Hentze, M. W. (1995) RNA 1, 155-163.
105. Henderson, B. R. & Kühn, L. C (1995) J. Biol. Chem. 270, 20509-20515.
106. Philpott, C. C., Haile, D., Rouault, T. A. & Klausner, R. D. (1993) J. Biol. Chem. 268, 17655-17658.
107. Philpott, C. C., Klausner, R. D. & Rouault, T. A. (1994) Proc. Natl. Acad. Sci. USA 91, 7321-7325.
108. DeRusso, P.A., Philpott, C.C., Iwai, K., Mostowski, H. S., Klausner, R. D. & Rouault, T. A. (1995) J. Biol. Chem. 270, 15451-15454.
109. Robbins, A. H. & Stout, C. D. (1989) Proteins 5, 289-312.
110. Robbins, A. H. & Stout, C. D. (1989) Proc. Natl Acad. Sci. USA 86, 3639-3643.
111. Basilion, J. P., Rouault, T. A., Massinople, C. M., Klausner, R. D. & Burgess, W. H. (1994) Proc. Natl. Acad. Sci. USA 91, 574-578.
112. Neupert, B., Menotti, E. & Kühn, L. C. (1995) Nucleic Acids Res 23, 2579-2583.
113. Swenson, G. R. & Walden, W. E. (1994) Nucleic Acids Res. 22, 2627-2633.
114. Quo, B., Brown, F. M., Phillips, J. D., Yu, Y. & Leibold, E. A. (1995) J. Biol. Chem. 270, 16529-16535.
115. Rouault, T. A., Haile, D. J., Downey, W. E., Philpott, C. C., Tang, C, Samaniego, F., Chin, J., Paul, I., Orloff, D., Harford, J. B. & Klausner, R. D. (1992) BioMetals 5, 131-140.
116. Iwai, K., Klausner, R. D. & Rouault, T. A. (1995) EMBO J. 14, 5360-5357.
117. Guo, B., Phillips, J. D., Yu, Y. & Leibold, E. A. (1995) J. Biol. Chem. 270, 21645-21651.
118. Goessling, L. S., Daniels-McQueen, S., Bhattacharyya-Pakrasi, M., Lin, J.-J. & Thach, R. E. (1992) Science 256, 670-673.
119. Lin, J.-J., Daniels-McQueen, S., Patino, M. M., Gaffield, L., Walden, W. E. & Thach, R. E. (1990) Science 247, 74-77.
120. Lin, J.-J., Patino, M. M., Gaffield, L., Walden, W. E., Smith, A. & Thach, R. E. (1991) Proc Natl. Acad. Sci. USA 88, 6068-6071.
121. Haile, D. J., Rouault, T. A., Harford, J. B. & Klausner, R. D. (1990) J. Biol. Chem. 265, 12786-12789.
122. Lancaster, J. R. & Hibbs, J. B. (1990) Proc. Natl. Acad. Sci USA 87, 1223-1227.
123. Pellat, C., Henry, Y. & Drapier, J.-C. (1990) Biochem. Biophys. Res. Commun. 166, 119-125.
124. Henry, Y., Lepoivre, M., Drapier, J.-C., Ducrocq, C., Boucher, J.-L. & Guissani, A. (1993) FASEB J. 7, 1124-1134.
125. Drapier, J.-C, Hirling, H., Wietzerbin, J., Kaldy, P. & Kühn, L. C. (1993) EMBO J. 12, 3643-3649.
126. Weiss, G., Goossen, B., Doppier, W., Fuchs, D., Pantopoulos, K., Werner-Felmayer, G., Wachter, H. & Hentze, M. W, (1993) EMBO J. 12, 3651-3657.
127. Richardson, D. R., Neumannova, V., Nagy, E. & Ponka, P. (1995) Blood 86, 3211-3219.
128. Oria, R., Sanchez, L., Houston, T., Hentze, M. W., Liew, F. Y. & Brock, J. M. (1995) Blood 85, 2962-2966.
129. Jaffrey, S. R., Cohen, N. A., Rouault, T. A., Klausner, R. D. & Snyder, S. H. (1994) Proc. Natl. Acad. Sci. USA 91, 12994-12998.
130. Pantopoulos, K. & Hentze, M. W. (1995) Proc. Natl. Acad. Sci. USA 92, 1267-1271.
131. Pantopoulos, K., Weiss, G. & Hentze, M. W. (1996) Mol. Cell. Biol. 16, 3781-3788.
132. Weiss, G., Werner-Felmayer, G., Werner, E. R., Grunewald, K., Wachter, H. & Hentze, M. W. (1994) J. Exp. Med. 180, 969-976.
133. Smith, C., Mitchinson, M. J., Aruoma, O. I. & Halliwell (1992) Biochem. J. 286, 901-905.
134. Hershko, C. (1994) Baillieres Clin Haematol. 7, 965-1000.
135. Morris, C. J., Earl, J. R., Trenam, C. W. & Blake, D. R. (1995) Int. J. Biochem. Cell. Biol. 27, 109-122.
136. Touati, D., Jacques, M., Tardat, B., Bouchard, L. & Despied, S. (1995) J. Bacteriol. 177, 2305-2314.
137. Tardat, B. & Touati, D. (1993) Mol. Microbiol. 9, 53-63.
138. Martins, E. A. L., Robalinho, R. L. & Meneghini, R. (1995) Arch Biochem. Biophys. 316, 128-134.
139. Pantopoulos, K. & Hentze, M. W. (1995) EMBO J. 14, 2917-2924.
140. Hausladen, A. & Fridovich. I. (1994) J. Biol. Chem. 269, 29405-29408.
141. Toth, I. & Bridges, K. R. (1995) J. Biol. Chem. 270, 19540-19544.
142. Eisenstein, R. S., Tuazon, P. T., Schalinske, K. L., Anderson, S. A. & Traugh, J. A. (1993) J. Biol. Chem. 268, 27363-27370.
143. Cerutti, P. A. (1985) Science 227, 375-381.
144. Meyer, M., Schreck, R. & Baeuerle, P. A. (1993) EMBO J. 12, 2005-2015.
145. Youdim, M. B. H., Ben-Shachar, D. & Riederer, P. (1993) Movement Disorders 8, 1-12.
146. Hidalgo, E. & Demple, B. (1994) EMBO J. 13, 138-146.
147. Khoroshilova, N., Beinert, H. & Kiley, P. J. (1995) Proc. Natl. Acad. Sci. USA 92, 2499-2503.
148. Li, P. M., Reichert, J., Freyd, G., Horvitz, H. R. & Walsh, C. T. (1991) Proc. Natl. Acad. Sci. USA 88, 9210-9213.
149. Vile, G. F. & Tyrrell, R. M. (1993) J. Biol. Chem. 268, 14678-14681.
150. Balla, J., Jacob, H. S., Balla, G., Nath, K., Eaton, J. W. & Vercellotti, G. M. (1993) Proc. Natl. Acad. Sci. USA 90, 9285-9289.
151. Cairo, G., Tacchini, L., Pogliaghi, G., Anzon, E., Tomasi, A. & Bernelli-Zazzera, A. (1995) J. Biol. Chem. 270, 700-703.