Mouse brains deficient in H-ferritin have normal iron concentration but a protein profile of iron deficiency and increased evidence of oxidative stress

Journal of Neuroscience Research

Volumn 71, Issue 1, 2003, Pages 46-63

  Thompson, Khristy ^a   Menzies, Sharon ^a   Muckenthaler, Martina ^b   Torti, Frank M ^c   Wood, Teresa ^a   Torti, Suzy V ^c   Hentze, Matthias W ^b   Beard, John ^d   Connor, James ^a  

^a PENN STATE COLLEGE OF MEDICINE   (United States)

^b EUROPEAN MOLECULAR BIOLOGY LABORATORY   (Germany)

^c WAKE FOREST SCHOOL OF MEDICINE   (United States)

^d PENNSYLVANIA STATE UNIVERSITY   (United States)

Author keywords

Alzheimer's disease; Ferritin; Iron; Iron proteins; Mice; Neurodegeneration; Null mutant; Oxidative stress; Parkinson's disease

Indexed keywords

CASPASE 3; FERRITIN; FERRITIN H; IRON; PROTEIN BAX; SUPEROXIDE DISMUTASE; TRANSFERRIN; TRANSFERRIN RECEPTOR; UNCLASSIFIED DRUG;

ALZHEIMER DISEASE; ANIMAL EXPERIMENT; ANIMAL MODEL; ANIMAL TISSUE; ARTICLE; CONTROLLED STUDY; DEGENERATIVE DISEASE; ENZYME ACTIVITY; GENE MUTATION; HETEROZYGOSITY; HISTOPATHOLOGY; HOMOZYGOSITY; IRON BLOOD LEVEL; IRON DEFICIENCY; IRON STORAGE; MOUSE; NONHUMAN; NULL ALLELE; OXIDATIVE STRESS; PARKINSON DISEASE; PRIORITY JOURNAL; PROTEIN MODIFICATION;

ALZHEIMER DISEASE; ANIMALS; APOFERRITINS; BCL-2-ASSOCIATED X PROTEIN; BRAIN; CASPASE 3; CASPASES; CATION TRANSPORT PROTEINS; CEREBELLAR CORTEX; CEREBELLUM; CERULOPLASMIN; CORPUS STRIATUM; DISEASE MODELS, ANIMAL; FERRITINS; GENE EXPRESSION PROFILING; GENE TARGETING; GENOTYPE; HEME OXYGENASE (DECYCLIZING); HIPPOCAMPUS; IMMUNOCHEMISTRY; IRON; IRON-BINDING PROTEINS; MICE; MICE, INBRED C57BL; MICE, TRANSGENIC; OXIDATIVE STRESS; PARKINSON DISEASE; PHENOTYPE; PROTO-ONCOGENE PROTEINS; PROTO-ONCOGENE PROTEINS C-BCL-2; RECEPTORS, TRANSFERRIN; SUPEROXIDE DISMUTASE; TRANSFERRIN;

EID: 0037216723     PISSN: 03604012     EISSN: None     Source Type: Journal    
DOI: 10.1002/jnr.10463     Document Type: Article

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