-
2
-
-
0034663989
-
HIF-1 and human disease: One highly involved factor
-
(2000)
Genes Dev
, vol.14
, pp. 1983-1991
-
-
Semenza, G.L.1
-
6
-
-
0030961006
-
Hypoxia-inducible factor 1α (HIF-1α) protein is rapidly degraded by the ubiquitin-proteasome system under normoxic conditions: Its stabilization by hypoxia depends upon redox-induced changes
-
(1997)
J Biol Chem
, vol.272
, pp. 22642-22647
-
-
Salceda, S.1
Caro, J.2
-
10
-
-
0033587146
-
The tumour suppressor protein VHL targets hypoxia-inducible factors for oxygen-dependent proteolysis
-
(1999)
Nature
, vol.399
, pp. 271-275
-
-
Maxwell, P.H.1
Wiesener, M.S.2
Chang, G.W.3
Clifford, S.C.4
Vaux, E.C.5
Cockman, M.E.6
Wykoff, C.C.7
Pugh, C.W.8
Maher, E.R.9
Ratcliffe, P.J.10
-
11
-
-
0034682783
-
Hypoxia inducible factor-α binding and ubiquitylation by the von Hippel-Lindau tumor suppressor protein
-
(2000)
J Biol Chem
, vol.275
, pp. 25733-25741
-
-
Cockman, M.E.1
Masson, N.2
Mole, D.R.3
Jaakkola, P.4
Chang, G.W.5
Clifford, S.C.6
Maher, E.R.7
Pugh, C.W.8
Ratcliffe, P.J.9
Maxwell, P.H.10
-
13
-
-
0033776536
-
Ubiquitination of hypoxia-inducible factor requires direct binding to the β-domain of the von Hippel-Lindau protein
-
(2000)
Nat Cell Biol
, vol.2
, pp. 423-427
-
-
Ohh, M.1
Park, C.W.2
Ivan, M.3
Hoffman, M.A.4
Kim, T.Y.5
Huang, L.E.6
Pavletich, N.7
Chau, V.8
Kaelin, W.G.9
-
17
-
-
0033954247
-
Regulation of tumor angiogenesis by p53-induced degradation of hypoxia-inducible factor 1α
-
(2000)
Genes Dev
, vol.14
, pp. 34-44
-
-
Ravi, R.1
Mookerjee, B.2
Bhujwalla, Z.M.3
Sutter, C.H.4
Artemov, D.5
Zeng, Q.6
Dillehay, L.E.7
Madan, A.8
Semenza, G.L.9
Bedi, A.10
-
18
-
-
0034654174
-
Modulation of hypoxia-inducible factor 1α expression by the epidermal growth factor/phosphatidylinositol 3-kinase/PTEN/AKT/FRAP pathway in human prostate cancer cells: Implications for tumor angiogenesis and therapeutics
-
(2000)
Cancer Res
, vol.60
, pp. 1541-1545
-
-
Zhong, H.1
Chiles, K.2
Feldser, D.3
Laughner, E.4
Hanrahan, C.5
Georgescu, M.M.6
Simons, J.W.7
Semenza, G.L.8
-
19
-
-
0034050050
-
Loss of PTEN facilitates HIF-1-mediated gene expression
-
(2000)
Genes Dev
, vol.14
, pp. 391-396
-
-
Zundel, W.1
Schindler, C.2
Haas-Kogan, D.3
Koong, A.4
Kaper, F.5
Chen, E.6
Gottschalk, A.R.7
Ryan, H.E.8
Johnson, R.S.9
Jefferson, A.B.10
-
22
-
-
0033118983
-
Molecular mechanisms of transcription activation by HLF and HIF1α in response to hypoxia: Their stabilization and redox signal-induced interaction with CBP/p300
-
(1999)
EMBO J
, vol.18
, pp. 1905-1914
-
-
Ema, M.1
Hirota, K.2
Mimura, J.3
Abe, H.4
Yodoi, J.5
Sogawa, K.6
Poellinger, L.7
Fujii-Kuriyama, Y.8
-
26
-
-
0033529656
-
Perspectives on oxygen sensing
-
(1999)
Cell
, vol.98
, pp. 281-284
-
-
Semenza, G.L.1
-
31
-
-
0034647933
-
Antioxidant/pro-oxidant equilibrium regulates HIF-1α-NF-κB redox sensitivity: Evidence for inhibition by glutathione oxidation in alveolar epithelial cells
-
(2000)
J Biol Chem
, vol.275
, pp. 21130-21139
-
-
Haddad, J.J.1
Olver, R.E.2
Land, S.C.3
-
34
-
-
0032574765
-
Iron-dependent oxidation, ubiquitination, and degradation of iron regulatory protein 2: Implications for degradation of oxidized proteins
-
(1998)
Proc Natl Acad Sci USA
, vol.95
, pp. 4924-4928
-
-
Iwai, K.1
Drake, S.K.2
Wehr, N.B.3
Weissman, A.M.4
LaVaute, T.5
Minato, N.6
Klausner, R.D.7
Levine, R.L.8
Rouault, T.A.9
-
38
-
-
0033975850
-
Hypoxia response element of the human vascular endothelial growth factor gene mediates transcriptional regulation by nitric oxide: Control of hypoxia-inducible factor-1 activity by nitric oxide
-
(2000)
Blood
, vol.95
, pp. 189-197
-
-
Kimura, H.1
Weisz, A.2
Kurashima, Y.3
Hashimoto, K.4
Ogura, T.5
D'Acquisto, F.6
Addeo, R.7
Makuuchi, M.8
Esumi, H.9
-
41
-
-
0034665113
-
Nitric oxide affects the production of reactive oxygen species in hepatoma cells: Implications for the process of oxygen sensing
-
(2000)
Free Radic Biol Med
, vol.29
, pp. 515-521
-
-
Genius, J.1
Fandrey, J.2
-
46
-
-
0033538439
-
Nitric oxide contributes to behavioral, cellular, and developmental responses to low oxygen in Drosophila
-
(1999)
Cell
, vol.98
, pp. 105-114
-
-
Wingrove, J.A.1
O'Farrell, P.H.2
-
47
-
-
0033529173
-
2 sensing is preserved in mice lacking the gp91 phox subunit of NADPH oxidase
-
(1999)
Proc Natl Acad Sci USA
, vol.96
, pp. 7944-7949
-
-
Archer, S.L.1
Reeve, H.L.2
Michelakis, E.3
Puttagunta, L.4
Waite, R.5
Nelson, D.P.6
Dinauer, M.C.7
Weir, E.K.8
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