-
1
-
-
0030744876
-
Mutation in the alpha-synuclein gene identified in families with Parkinson's disease
-
Polymeropoulos MH, Lavedan C, Leroy E, et al. Mutation in the alpha-synuclein gene identified in families with Parkinson's disease. Science 1997;276:2045-2047.
-
(1997)
Science
, vol.276
, pp. 2045-2047
-
-
Polymeropoulos, M.H.1
Lavedan, C.2
Leroy, E.3
-
2
-
-
0031990490
-
Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease
-
Kruger R, Kuhn W, Muller T, et al. Ala30Pro mutation in the gene encoding alpha-synuclein in Parkinson's disease. Nat Genet 1998;18:106-108.
-
(1998)
Nat Genet
, vol.18
, pp. 106-108
-
-
Kruger, R.1
Kuhn, W.2
Muller, T.3
-
3
-
-
0032499264
-
Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism
-
Kitada T, Asakawa S, Hattori N, et al. Mutations in the parkin gene cause autosomal recessive juvenile parkinsonism. Nature 1998;392:605-608.
-
(1998)
Nature
, vol.392
, pp. 605-608
-
-
Kitada, T.1
Asakawa, S.2
Hattori, N.3
-
4
-
-
0345490853
-
A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease
-
Abbas N, Lucking CB, Ricard S, et al. A wide variety of mutations in the parkin gene are responsible for autosomal recessive parkinsonism in Europe. French Parkinson's Disease Genetics Study Group and the European Consortium on Genetic Susceptibility in Parkinson's Disease. Hum Mol Genet 1999;8:567-574.
-
(1999)
Hum Mol Genet
, vol.8
, pp. 567-574
-
-
Abbas, N.1
Lucking, C.B.2
Ricard, S.3
-
5
-
-
0032190090
-
The ubiquitin pathway in Parkinson's disease
-
Leroy E, Boyer R, Auburger G, et al. The ubiquitin pathway in Parkinson's disease. Nature 1998;395:451-452.
-
(1998)
Nature
, vol.395
, pp. 451-452
-
-
Leroy, E.1
Boyer, R.2
Auburger, G.3
-
6
-
-
0037067993
-
Differential localization of alpha-, beta- and gamma-synucleins in the rat CNS
-
Li JY, Henning Jensen P, Dahlstrom A. Differential localization of alpha-, beta- and gamma-synucleins in the rat CNS. Neuroscience 2002;113:463-478.
-
(2002)
Neuroscience
, vol.113
, pp. 463-478
-
-
Li, J.Y.1
Henning Jensen, P.2
Dahlstrom, A.3
-
7
-
-
11144353557
-
The relevance of iron in the pathogenesis of Parkinson's disease
-
Gotz ME, Double K, Gerlach M, et al. The relevance of iron in the pathogenesis of Parkinson's disease. Ann NY Acad Sci 2004;1012:193-208.
-
(2004)
Ann NY Acad Sci
, vol.1012
, pp. 193-208
-
-
Gotz, M.E.1
Double, K.2
Gerlach, M.3
-
9
-
-
0021313312
-
Modulation of dopamine receptor in the striatum by iron: Behavioral and biochemical correlates
-
Youdim MB, Ashkenazi R, Ben-Shachar D, Yehuda S. Modulation of dopamine receptor in the striatum by iron: behavioral and biochemical correlates. Adv Neurol 1984;40:159-170.
-
(1984)
Adv Neurol
, vol.40
, pp. 159-170
-
-
Youdim, M.B.1
Ashkenazi, R.2
Ben-Shachar, D.3
Yehuda, S.4
-
10
-
-
0027340258
-
T2 relaxation time in patients with Parkinson's disease
-
Antonini A, Leenders KL, Meier D, et al. T2 relaxation time in patients with Parkinson's disease. Neurology 1993;43:697-700.
-
(1993)
Neurology
, vol.43
, pp. 697-700
-
-
Antonini, A.1
Leenders, K.L.2
Meier, D.3
-
11
-
-
0028726417
-
Iron histochemistry of the substantia nigra in Parkinson's disease
-
Morris CM, Edwardson JA. Iron histochemistry of the substantia nigra in Parkinson's disease. Neurodegeneration 1994;3:277-282.
-
(1994)
Neurodegeneration
, vol.3
, pp. 277-282
-
-
Morris, C.M.1
Edwardson, J.A.2
-
12
-
-
0026666528
-
Iron-melanin complex in substantia nigra of parkinsonian brains: An x-ray microanalysis
-
Jellinger K, Kienzl E, Rumpelmair G, et al. Iron-melanin complex in substantia nigra of parkinsonian brains: an x-ray microanalysis. J Neurochem 1992;59:1168-1171.
-
(1992)
J Neurochem
, vol.59
, pp. 1168-1171
-
-
Jellinger, K.1
Kienzl, E.2
Rumpelmair, G.3
-
14
-
-
0026739170
-
Histochemical distribution of non-haem iron in the human brain
-
Morris CM, Candy JM, Oakley AE, et al. Histochemical distribution of non-haem iron in the human brain. Acta Anat (Basel) 1992;144:235-257.
-
(1992)
Acta Anat (Basel)
, vol.144
, pp. 235-257
-
-
Morris, C.M.1
Candy, J.M.2
Oakley, A.E.3
-
15
-
-
0025763177
-
Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease
-
Gibb WR, Lees AJ. Anatomy, pigmentation, ventral and dorsal subpopulations of the substantia nigra, and differential cell death in Parkinson's disease. J Neurol Neurosurg Psychiatry 1991;54:388-396.
-
(1991)
J Neurol Neurosurg Psychiatry
, vol.54
, pp. 388-396
-
-
Gibb, W.R.1
Lees, A.J.2
-
16
-
-
0028960864
-
Short- and long-term changes in striatal and extrastriatal dopamine uptake sites in the MPTP-treated common marmoset
-
Gnanalingham KK, Milkowski NA, Smith LA, et al. Short- and long-term changes in striatal and extrastriatal dopamine uptake sites in the MPTP-treated common marmoset. Eur J Pharmacol 1995;277:235-241.
-
(1995)
Eur J Pharmacol
, vol.277
, pp. 235-241
-
-
Gnanalingham, K.K.1
Milkowski, N.A.2
Smith, L.A.3
-
17
-
-
0034235742
-
Striatal responses to partial dopaminergic lesion: Evidence for compensatory sprouting
-
Song DD, Haber SN. Striatal responses to partial dopaminergic lesion: evidence for compensatory sprouting. J Neurosci 2000;20:5102-5114.
-
(2000)
J Neurosci
, vol.20
, pp. 5102-5114
-
-
Song, D.D.1
Haber, S.N.2
-
18
-
-
84961042345
-
The effect of age on the nonhaemin iron in the human brain
-
Hallgren B, Sourander P. The effect of age on the nonhaemin iron in the human brain. J Neurochem 1958;3:41-51.
-
(1958)
J Neurochem
, vol.3
, pp. 41-51
-
-
Hallgren, B.1
Sourander, P.2
-
20
-
-
33646375711
-
High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease
-
Bender A, Krishnan KJ, Morris CM, et al. High levels of mitochondrial DNA deletions in substantia nigra neurons in aging and Parkinson disease. Nat Genet 2006;38:515-517.
-
(2006)
Nat Genet
, vol.38
, pp. 515-517
-
-
Bender, A.1
Krishnan, K.J.2
Morris, C.M.3
-
21
-
-
17744393686
-
Mitochondrial DNA mutations in human disease
-
Taylor RW, Turnbull DM. Mitochondrial DNA mutations in human disease. Nat Rev Genet 2005;6:389-402.
-
(2005)
Nat Rev Genet
, vol.6
, pp. 389-402
-
-
Taylor, R.W.1
Turnbull, D.M.2
-
22
-
-
23944491628
-
In situ characterization and mapping of iron compounds in Alzheimer's disease tissue
-
Collingwood JF, Mikhaylova A, Davidson M, et al. In situ characterization and mapping of iron compounds in Alzheimer's disease tissue. J Alzheimers Dis 2005;7:267-272.
-
(2005)
J Alzheimers Dis
, vol.7
, pp. 267-272
-
-
Collingwood, J.F.1
Mikhaylova, A.2
Davidson, M.3
-
23
-
-
33644480509
-
Detection, identification and mapping of iron anomalies in brain tissue using x-ray absorption spectroscopy
-
Mikhailova A, Davidson M, Channel JET, Guyodo Y, Batich C, Dobson J. Detection, identification and mapping of iron anomalies in brain tissue using x-ray absorption spectroscopy. J Roy Soc Interface 2005;2:33-37.
-
(2005)
J Roy Soc Interface
, vol.2
, pp. 33-37
-
-
Mikhailova, A.1
Davidson, M.2
Channel, J.E.T.3
Guyodo, Y.4
Batich, C.5
Dobson, J.6
-
24
-
-
0030948515
-
Iron in the Parkinsonian substantia nigra
-
Gerlach M, Double K, Riederer P, et al. Iron in the Parkinsonian substantia nigra. Mov Disord 1997;12:258-260.
-
(1997)
Mov Disord
, vol.12
, pp. 258-260
-
-
Gerlach, M.1
Double, K.2
Riederer, P.3
-
25
-
-
0034941118
-
Mutation in the gene encoding ferritin light polypeptide causes dominant adultonset basal ganglia disease
-
Curtis AR, Fey C, Morris CM, et al. Mutation in the gene encoding ferritin light polypeptide causes dominant adultonset basal ganglia disease. Nat Genet 2001;28:350-354.
-
(2001)
Nat Genet
, vol.28
, pp. 350-354
-
-
Curtis, A.R.1
Fey, C.2
Morris, C.M.3
-
26
-
-
0025963530
-
Selective increase of iron in substantia nigra zona compacta of parkinsonian brains
-
Sofic E, Paulus W, Jellinger K, et al. Selective increase of iron in substantia nigra zona compacta of parkinsonian brains. J Neurochem 1991;56:978-982.
-
(1991)
J Neurochem
, vol.56
, pp. 978-982
-
-
Sofic, E.1
Paulus, W.2
Jellinger, K.3
-
27
-
-
0032898122
-
-
Griffiths PD, Dobson BR, Jones GR, Clarke DT. Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryoelectron microscopy. Brain 122:667-673.
-
Griffiths PD, Dobson BR, Jones GR, Clarke DT. Iron in the basal ganglia in Parkinson's disease. An in vitro study using extended X-ray absorption fine structure and cryoelectron microscopy. Brain 122:667-673.
-
-
-
-
28
-
-
1342285717
-
Mossbauer spectroscopy and ELISA studies reveal differences between Parkinson's disease and control substantia nigra
-
Galazka-Friedman J, Bauminger ER, Koziorowski D, Friedman A. Mossbauer spectroscopy and ELISA studies reveal differences between Parkinson's disease and control substantia nigra. Biochim Biophys Acta 2004;1688:130-136.
-
(2004)
Biochim Biophys Acta
, vol.1688
, pp. 130-136
-
-
Galazka-Friedman, J.1
Bauminger, E.R.2
Koziorowski, D.3
Friedman, A.4
-
29
-
-
10744223491
-
Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis
-
Meyron-Holtz EG, Ghosh MC, Iwai K, et al. Genetic ablations of iron regulatory proteins 1 and 2 reveal why iron regulatory protein 2 dominates iron homeostasis. Embo J 2004;23:386-395.
-
(2004)
Embo J
, vol.23
, pp. 386-395
-
-
Meyron-Holtz, E.G.1
Ghosh, M.C.2
Iwai, K.3
-
30
-
-
0035138456
-
Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice
-
LaVaute T, Smith S, Cooperman S, et al. Targeted deletion of the gene encoding iron regulatory protein-2 causes misregulation of iron metabolism and neurodegenerative disease in mice. Nat Genet 2001;27:209-214.
-
(2001)
Nat Genet
, vol.27
, pp. 209-214
-
-
LaVaute, T.1
Smith, S.2
Cooperman, S.3
-
31
-
-
0031794794
-
Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease
-
Mezey E, Dehejia AM, Harta G, et al. Alpha synuclein is present in Lewy bodies in sporadic Parkinson's disease. Mol Psychiatry 1998;3:493-499.
-
(1998)
Mol Psychiatry
, vol.3
, pp. 493-499
-
-
Mezey, E.1
Dehejia, A.M.2
Harta, G.3
-
32
-
-
0034663039
-
The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity
-
Ostrerova-Golts N, Petrucelli L, Hardy J, et al. The A53T alpha-synuclein mutation increases iron-dependent aggregation and toxicity. J Neurosci 2000;20:6048-6054.
-
(2000)
J Neurosci
, vol.20
, pp. 6048-6054
-
-
Ostrerova-Golts, N.1
Petrucelli, L.2
Hardy, J.3
-
33
-
-
0035941201
-
Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure
-
Uversky VN, Li J, Fink AL. Metal-triggered structural transformations, aggregation, and fibrillation of human alpha-synuclein. A possible molecular NK between Parkinson's disease and heavy metal exposure. J Biol Chem 2001;276:44284-44296.
-
(2001)
J Biol Chem
, vol.276
, pp. 44284-44296
-
-
Uversky, V.N.1
Li, J.2
Fink, A.L.3
-
34
-
-
0035873812
-
Alpha-synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro
-
Turnbull S, Tabner BJ, El-Agnaf OM, et al. Alpha-synuclein implicated in Parkinson's disease catalyses the formation of hydrogen peroxide in vitro. Free Radic Biol Med 2001;30:1163-1170.
-
(2001)
Free Radic Biol Med
, vol.30
, pp. 1163-1170
-
-
Turnbull, S.1
Tabner, B.J.2
El-Agnaf, O.M.3
-
35
-
-
0036670712
-
Aggregation and neurotoxicity of alpha-synuclein and related peptides
-
el-Agnaf OM, Irvine GB. Aggregation and neurotoxicity of alpha-synuclein and related peptides. Biochem Soc Trans 2002;30:559-565.
-
(2002)
Biochem Soc Trans
, vol.30
, pp. 559-565
-
-
el-Agnaf, O.M.1
Irvine, G.B.2
-
36
-
-
0034935036
-
A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome
-
Zhou B, Westaway SK, Levinson B, et al. A novel pantothenate kinase gene (PANK2) is defective in Hallervorden-Spatz syndrome. Nat Genet 2001;28:345-349.
-
(2001)
Nat Genet
, vol.28
, pp. 345-349
-
-
Zhou, B.1
Westaway, S.K.2
Levinson, B.3
-
37
-
-
0037413484
-
Genetic, clinical, and radiographic delineation of Hallervorden-Spatz syndrome
-
Hayflick SJ, Westaway SK, Levinson B, et al. Genetic, clinical, and radiographic delineation of Hallervorden-Spatz syndrome. N Engl J Med 2003;348:33-40.
-
(2003)
N Engl J Med
, vol.348
, pp. 33-40
-
-
Hayflick, S.J.1
Westaway, S.K.2
Levinson, B.3
|