The hemochromatosis gene product complexes with the transferrin receptor and lowers its affinity for ligand binding

Proceedings of the National Academy of Sciences of the United States of America

Volumn 95, Issue 4, 1998, Pages 1472-1477

  Feder, John N ^a   Penny, David M ^a   Irrinki, Alivelu ^a   Lee, Vince K ^a   Lebrón, José A ^b   Watson, Nicole ^a   Tsuchihashi, Zenta ^a   Sigal, Elliott ^a   Bjorkman, Pamela J ^b   Schatzman, Randall C ^a  

^a Progenitor Inc   (United States)

^b CALIFORNIA INSTITUTE OF TECHNOLOGY   (United States)

Author keywords

[No Author keywords available]

Indexed keywords

GENE PRODUCT; IODINE 125; TRANSFERRIN; TRANSFERRIN RECEPTOR;

ARTICLE; AUTOSOMAL RECESSIVE DISORDER; BINDING AFFINITY; GENE MUTATION; GENE OVEREXPRESSION; HELA CELL; HEMOCHROMATOSIS; HUMAN; HUMAN CELL; INBORN ERROR OF METABOLISM; IRON METABOLISM; LIGAND BINDING; PRIORITY JOURNAL; PROTEIN EXPRESSION;

AMINO ACID SEQUENCE; BETA 2-MICROGLOBULIN; DIMERIZATION; HEMOCHROMATOSIS; HISTOCOMPATIBILITY ANTIGENS CLASS I; HLA ANTIGENS; HUMANS; LIGANDS; MEMBRANE PROTEINS; POINT MUTATION; PRECIPITIN TESTS; PROTEIN BINDING; RECEPTORS, TRANSFERRIN; STRUCTURE-ACTIVITY RELATIONSHIP; TRANSFECTION; TRANSFERRIN;

EID: 13144282684     PISSN: 00278424     EISSN: None     Source Type: Journal    
DOI: 10.1073/pnas.95.4.1472     Document Type: Article

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