메뉴 건너뛰기




Volumn 22, Issue 24, 2002, Pages 10690-10698

Endoplasmic reticulum stress and the unfolded protein response in cellular models of Parkinson's disease

Author keywords

6 hydroxydopamine; CHOP; Endoplasmic reticulum; Parkinson's disease; PERK; Unfolded protein response

Indexed keywords

1 METHYL 4 PHENYLPYRIDINIUM; OXIDOPAMINE; PROTEIN KINASE; ROTENONE;

EID: 0037114971     PISSN: 02706474     EISSN: None     Source Type: Journal    
DOI: 10.1523/jneurosci.22-24-10690.2002     Document Type: Article
Times cited : (508)

References (58)
  • 2
    • 0035947372 scopus 로고    scopus 로고
    • Impairment of the ubiquitin-proteasome system by protein aggregation
    • Bence NF, Sampat RM, Kopito RR (2001) Impairment of the ubiquitin-proteasome system by protein aggregation. Science 292:1552-1555.
    • (2001) Science , vol.292 , pp. 1552-1555
    • Bence, N.F.1    Sampat, R.M.2    Kopito, R.R.3
  • 3
    • 0033782015 scopus 로고    scopus 로고
    • Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response
    • Bertolotti A, Zhang Y, Hendershot LM, Harding HP, Ron D (2000) Dynamic interaction of BiP and ER stress transducers in the unfolded-protein response. Nat Cell Biol 2:326-332.
    • (2000) Nat Cell Biol , vol.2 , pp. 326-332
    • Bertolotti, A.1    Zhang, Y.2    Hendershot, L.M.3    Harding, H.P.4    Ron, D.5
  • 6
    • 0033118409 scopus 로고    scopus 로고
    • Complexes containing activating transcription factor (ATF)/cAMP-responsive element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response
    • Fawcett TW, Martindale JL, Guyton KZ, Hai T, Holbrook NJ (1999) Complexes containing activating transcription factor (ATF)/cAMP-responsive element-binding protein (CREB) interact with the CCAAT/enhancer-binding protein (C/EBP)-ATF composite site to regulate Gadd153 expression during the stress response. Biochem J 339: 135-141.
    • (1999) Biochem J , vol.339 , pp. 135-141
    • Fawcett, T.W.1    Martindale, J.L.2    Guyton, K.Z.3    Hai, T.4    Holbrook, N.J.5
  • 7
    • 0035736259 scopus 로고    scopus 로고
    • Organelle-specific initiation of cell death pathways
    • Ferri KF, Kroemer G (2001) Organelle-specific initiation of cell death pathways. Nat Cell Biol 3:E255-E263.
    • (2001) Nat Cell Biol , vol.3
    • Ferri, K.F.1    Kroemer, G.2
  • 8
    • 0033780610 scopus 로고    scopus 로고
    • A regulatory link between ER-associated protein degradation and the unfolded-protein response
    • Friedlander R, Jarosch E, Urban J, Volkwein C, Sommer T (2000) A regulatory link between ER-associated protein degradation and the unfolded-protein response. Nat Cell Biol 2:379-384.
    • (2000) Nat Cell Biol , vol.2 , pp. 379-384
    • Friedlander, R.1    Jarosch, E.2    Urban, J.3    Volkwein, C.4    Sommer, T.5
  • 9
    • 0024535437 scopus 로고
    • Intermediates in the aerobic autoxidation of 6-hydroxydopamine: Relative importance under different reaction conditions
    • Gee P, Davison AJ (1989) Intermediates in the aerobic autoxidation of 6-hydroxydopamine: Relative importance under different reaction conditions. Free Radic Biol Med 6:271-284.
    • (1989) Free Radic Biol Med , vol.6 , pp. 271-284
    • Gee, P.1    Davison, A.J.2
  • 10
    • 0345704610 scopus 로고
    • Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor
    • Greene LA, Tischler AS (1976) Establishment of a noradrenergic clonal line of rat adrenal pheochromocytoma cells which respond to nerve growth factor. Proc Natl Acad Sci USA 73:2424-2428.
    • (1976) Proc Natl Acad Sci USA , vol.73 , pp. 2424-2428
    • Greene, L.A.1    Tischler, A.S.2
  • 12
    • 0034043595 scopus 로고    scopus 로고
    • Neuroprotective strategies in Parkinson's disease using the models of 6-hydroxydopamine and MPTP
    • Grunblatt E, Mandel S, Youdim MB (2000) Neuroprotective strategies in Parkinson's disease using the models of 6-hydroxydopamine and MPTP. Ann NY Acad Sci 899:262-273.
    • (2000) Ann NY Acad Sci , vol.899 , pp. 262-273
    • Grunblatt, E.1    Mandel, S.2    Youdim, M.B.3
  • 13
    • 0029927983 scopus 로고    scopus 로고
    • Induction of the mammalian stress response gene Gadd153 by oxidative stress: Role of AP-1 element
    • Guyton KZ, Xu Q, Holbrook NJ (1996) Induction of the mammalian stress response gene Gadd153 by oxidative stress: Role of AP-1 element. Biochem J 314:547-554.
    • (1996) Biochem J , vol.314 , pp. 547-554
    • Guyton, K.Z.1    Xu, Q.2    Holbrook, N.J.3
  • 14
    • 0033590451 scopus 로고    scopus 로고
    • Protein translation and folding are coupled by an endoplasmic reticulum-resident kinase
    • Harding HP, Zhang Y, Ron D (1999) Protein translation and folding are coupled by an endoplasmic reticulum-resident kinase. Nature 397: 271-274.
    • (1999) Nature , vol.397 , pp. 271-274
    • Harding, H.P.1    Zhang, Y.2    Ron, D.3
  • 15
    • 0033634641 scopus 로고    scopus 로고
    • PERK is essential for translational regulation and cell survival during the unfolded protein response
    • Harding HP, Zhang Y, Bertolotti A, Zeng H, Ron D (2000a) PERK is essential for translational regulation and cell survival during the unfolded protein response. Mol Cell 5:897-904.
    • (2000) Mol Cell , vol.5 , pp. 897-904
    • Harding, H.P.1    Zhang, Y.2    Bertolotti, A.3    Zeng, H.4    Ron, D.5
  • 16
    • 0033634654 scopus 로고    scopus 로고
    • Regulated translation initiation controls stress-induced gene expression in mammalian cells
    • Harding HP, Novoa I, Zhang Y, Zeng H, Wek R, Schapira M, Ron D (2000b) Regulated translation initiation controls stress-induced gene expression in mammalian cells. Mol Cell 6:1099-1108.
    • (2000) Mol Cell , vol.6 , pp. 1099-1108
    • Harding, H.P.1    Novoa, I.2    Zhang, Y.3    Zeng, H.4    Wek, R.5    Schapira, M.6    Ron, D.7
  • 18
    • 0035796025 scopus 로고    scopus 로고
    • Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity, and cell death
    • Herceg Z, Wang ZQ (2001) Functions of poly(ADP-ribose) polymerase (PARP) in DNA repair, genomic integrity, and cell death. Mutat Res 477:97-110.
    • (2001) Mutat Res , vol.477 , pp. 97-110
    • Herceg, Z.1    Wang, Z.Q.2
  • 20
    • 0035967883 scopus 로고    scopus 로고
    • An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin
    • Imai Y, Soda M, Inoue H, Hattori N, Mizuno Y, Takahashi R (2001) An unfolded putative transmembrane polypeptide, which can lead to endoplasmic reticulum stress, is a substrate of Parkin. Cell 105:891-902.
    • (2001) Cell , vol.105 , pp. 891-902
    • Imai, Y.1    Soda, M.2    Inoue, H.3    Hattori, N.4    Mizuno, Y.5    Takahashi, R.6
  • 21
    • 0034717329 scopus 로고    scopus 로고
    • Transcription factor NRF2 coordinately regulates a group of oxidative stress-inducible genes in macrophages
    • Ishii T, Itoh K, Takahashi S, Sato H, Yanagawa T, Katoh Y, Bannai S, Yamamoto M (2000) Transcription factor NRF2 coordinately regulates a group of oxidative stress-inducible genes in macrophages. J Biol Chem 275:16023-16029.
    • (2000) J Biol Chem , vol.275 , pp. 16023-16029
    • Ishii, T.1    Itoh, K.2    Takahashi, S.3    Sato, H.4    Yanagawa, T.5    Katoh, Y.6    Bannai, S.7    Yamamoto, M.8
  • 22
    • 0028171676 scopus 로고
    • +)-induced cell death in PC12 cells: Inhibitory effects of several drugs
    • +)-induced cell death in PC12 cells: Inhibitory effects of several drugs. Neurochem Int 25:419-424.
    • (1994) Neurochem Int , vol.25 , pp. 419-424
    • Itano, Y.1    Kitamura, Y.2    Nomura, Y.3
  • 23
    • 0035104587 scopus 로고    scopus 로고
    • Caspase 3 inhibition attenuates hydrogen peroxide-induced DNA fragmentation but not cell death in neuronal PC12 cells
    • Jiang D, Jha N, Boonplueang R, Andersen JK (2001) Caspase 3 inhibition attenuates hydrogen peroxide-induced DNA fragmentation but not cell death in neuronal PC12 cells. J Neurochem 76:1745-1755.
    • (2001) J Neurochem , vol.76 , pp. 1745-1755
    • Jiang, D.1    Jha, N.2    Boonplueang, R.3    Andersen, J.K.4
  • 24
    • 0033562966 scopus 로고    scopus 로고
    • Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls
    • Kaufman RJ (1999) Stress signaling from the lumen of the endoplasmic reticulum: Coordination of gene transcriptional and translational controls. Genes Dev 13:1211-1233.
    • (1999) Genes Dev , vol.13 , pp. 1211-1233
    • Kaufman, R.J.1
  • 25
    • 0020680904 scopus 로고
    • Chronic parkinsonism in humans due to a product of meperidine-analog synthesis
    • Langston JW, Ballard P, Tetrud JW, Irwin I (1983) Chronic parkinsonism in humans due to a product of meperidine-analog synthesis. Science 219:979-980.
    • (1983) Science , vol.219 , pp. 979-980
    • Langston, J.W.1    Ballard, P.2    Tetrud, J.W.3    Irwin, I.4
  • 26
    • 0019132587 scopus 로고
    • Characterization of antisera raised against cultured rat sympathetic neurons
    • Lee VM, Shelanski ML, Greene LA (1980) Characterization of antisera raised against cultured rat sympathetic neurons. Neuroscience 5:2239-2245.
    • (1980) Neuroscience , vol.5 , pp. 2239-2245
    • Lee, V.M.1    Shelanski, M.L.2    Greene, L.A.3
  • 27
    • 0027263736 scopus 로고
    • Transfection with Trk restores "slow" NGF binding, efficient NGF uptake, and multiple NGF responses to NGF-nonresponsive PC12 cell mutants
    • Loeb DM, Greene LA (1993) Transfection with Trk restores "slow" NGF binding, efficient NGF uptake, and multiple NGF responses to NGF-nonresponsive PC12 cell mutants. J Neurosci 13:2919-2929.
    • (1993) J Neurosci , vol.13 , pp. 2919-2929
    • Loeb, D.M.1    Greene, L.A.2
  • 28
    • 0035879276 scopus 로고    scopus 로고
    • Stress-inducible transcription factor CHOP/Gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms
    • Maytin EV, Ubeda M, Lin JC, Habener JF (2001) Stress-inducible transcription factor CHOP/Gadd153 induces apoptosis in mammalian cells via p38 kinase-dependent and -independent mechanisms. Exp Cell Res 267:193-204.
    • (2001) Exp Cell Res , vol.267 , pp. 193-204
    • Maytin, E.V.1    Ubeda, M.2    Lin, J.C.3    Habener, J.F.4
  • 29
    • 0035144493 scopus 로고    scopus 로고
    • Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl-2 and perturbing the cellular redox state
    • McCullough KD, Martindale JL, Klotz LO, Aw TY, Holbrook NJ (2001) Gadd153 sensitizes cells to endoplasmic reticulum stress by down-regulating Bcl-2 and perturbing the cellular redox state. Mol Cell Biol 21:1249-1259.
    • (2001) Mol Cell Biol , vol.21 , pp. 1249-1259
    • McCullough, K.D.1    Martindale, J.L.2    Klotz, L.O.3    Aw, T.Y.4    Holbrook, N.J.5
  • 32
    • 0034716887 scopus 로고    scopus 로고
    • Tripartite management of unfolded proteins in the endoplasmic reticulum
    • Mori K (2000) Tripartite management of unfolded proteins in the endoplasmic reticulum. Cell 101:451-454.
    • (2000) Cell , vol.101 , pp. 451-454
    • Mori, K.1
  • 33
    • 0037154184 scopus 로고    scopus 로고
    • Recent advances in the genetics and pathogenesis of Parkinson disease
    • Mouradian MM (2002) Recent advances in the genetics and pathogenesis of Parkinson disease. Neurology 58:179-185.
    • (2002) Neurology , vol.58 , pp. 179-185
    • Mouradian, M.M.1
  • 35
    • 0031016498 scopus 로고    scopus 로고
    • 1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis
    • 1/S cell cycle blockers and inhibitors of cyclin-dependent kinases suppress camptothecin-induced neuronal apoptosis. J Neurosci 17:1256-1270.
    • (1997) J Neurosci , vol.17 , pp. 1256-1270
    • Park, D.S.1    Morris, E.J.2    Greene, L.A.3    Geller, H.M.4
  • 38
    • 0025939423 scopus 로고
    • Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms
    • Rukenstein A, Rydel RE, Greene LA (1991) Multiple agents rescue PC12 cells from serum-free cell death by translation- and transcription-independent mechanisms. J Neurosci 11:2552-2563.
    • (1991) J Neurosci , vol.11 , pp. 2552-2563
    • Rukenstein, A.1    Rydel, R.E.2    Greene, L.A.3
  • 39
    • 0001477595 scopus 로고
    • cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor
    • Rydel RE, Greene LA (1988) cAMP analogs promote survival and neurite outgrowth in cultures of rat sympathetic and sensory neurons independently of nerve growth factor. Proc Natl Acad Sci USA 85:1257-1261.
    • (1988) Proc Natl Acad Sci USA , vol.85 , pp. 1257-1261
    • Rydel, R.E.1    Greene, L.A.2
  • 40
    • 0032031011 scopus 로고    scopus 로고
    • Neural heme oxygenase-1 expression in idiopathic Parkinson's disease
    • Schipper HM, Liberman A, Stopa EG (1998) Neural heme oxygenase-1 expression in idiopathic Parkinson's disease. Exp Neurol 150:60-68.
    • (1998) Exp Neurol , vol.150 , pp. 60-68
    • Schipper, H.M.1    Liberman, A.2    Stopa, E.G.3
  • 41
    • 0023665208 scopus 로고
    • Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis
    • Scorsone KA, Panniers R, Rowlands AG, Henshaw EC (1987) Phosphorylation of eukaryotic initiation factor 2 during physiological stresses which affect protein synthesis. J Biol Chem 262:14538-14543.
    • (1987) J Biol Chem , vol.262 , pp. 14538-14543
    • Scorsone, K.A.1    Panniers, R.2    Rowlands, A.G.3    Henshaw, E.C.4
  • 42
    • 0031589740 scopus 로고    scopus 로고
    • Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors
    • Seaton TA, Cooper JM, Schapira AH (1997) Free radical scavengers protect dopaminergic cell lines from apoptosis induced by complex I inhibitors. Brain Res 777:110-118.
    • (1997) Brain Res , vol.777 , pp. 110-118
    • Seaton, T.A.1    Cooper, J.M.2    Schapira, A.H.3
  • 46
    • 0035894855 scopus 로고    scopus 로고
    • Expression of A53T mutant but not wild-type α-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death
    • Stefanis L, Larsen KE, Rideout HJ, Sulzer D, Greene LA (2001) Expression of A53T mutant but not wild-type α-synuclein in PC12 cells induces alterations of the ubiquitin-dependent degradation system, loss of dopamine release, and autophagic cell death. J Neurosci 21: 9549-9560.
    • (2001) J Neurosci , vol.21 , pp. 9549-9560
    • Stefanis, L.1    Larsen, K.E.2    Rideout, H.J.3    Sulzer, D.4    Greene, L.A.5
  • 48
    • 0032525990 scopus 로고    scopus 로고
    • A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (IRE1p) in mammalian cells
    • Tirasophon W, Welihinda AA, Kaufman RJ (1998) A stress response pathway from the endoplasmic reticulum to the nucleus requires a novel bifunctional protein kinase/endoribonuclease (IRE1p) in mammalian cells. Genes Dev 12:1812-1824.
    • (1998) Genes Dev , vol.12 , pp. 1812-1824
    • Tirasophon, W.1    Welihinda, A.A.2    Kaufman, R.J.3
  • 50
    • 0016361127 scopus 로고
    • Behavioral, physiological, and neurochemical changes after 6-hydroxydopamine-induced degeneration of the nigro-striatal dopamine neurons
    • Ungerstedt U, Ljungberg T, Steg G (1974) Behavioral, physiological, and neurochemical changes after 6-hydroxydopamine-induced degeneration of the nigro-striatal dopamine neurons. Adv Neurol 5:421-426.
    • (1974) Adv Neurol , vol.5 , pp. 421-426
    • Ungerstedt, U.1    Ljungberg, T.2    Steg, G.3
  • 51
    • 0034723235 scopus 로고    scopus 로고
    • Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1
    • Urano F, Wang X, Bertolotti A, Zhang Y, Chung P, Harding HP, Ron D (2000) Coupling of stress in the ER to activation of JNK protein kinases by transmembrane protein kinase IRE1. Science 287:664-666.
    • (2000) Science , vol.287 , pp. 664-666
    • Urano, F.1    Wang, X.2    Bertolotti, A.3    Zhang, Y.4    Chung, P.5    Harding, H.P.6    Ron, D.7
  • 53
    • 0030662269 scopus 로고    scopus 로고
    • Neuropathology of autonomic nervous system in Parkinson's disease
    • Wakabayashi K, Takahashi H (1997) Neuropathology of autonomic nervous system in Parkinson's disease. Eur Neurol 38:2-7.
    • (1997) Eur Neurol , vol.38 , pp. 2-7
    • Wakabayashi, K.1    Takahashi, H.2
  • 54
    • 0028127058 scopus 로고
    • Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis
    • Walkinshaw G, Waters CM (1994) Neurotoxin-induced cell death in neuronal PC12 cells is mediated by induction of apoptosis. Neuroscience 63:975-987.
    • (1994) Neuroscience , vol.63 , pp. 975-987
    • Walkinshaw, G.1    Waters, C.M.2
  • 56


* 이 정보는 Elsevier사의 SCOPUS DB에서 KISTI가 분석하여 추출한 것입니다.