Crystal structure and biochemical properties of the human mitochondrial ferritin and its mutant Ser144Ala

Journal of Molecular Biology

Volumn 340, Issue 2, 2004, Pages 277-293

  D'Estaintot, Béatrice Langlois ^a   Santambrogio, Paolo ^b   Granier, Thierry ^a   Gallois, Bernard ^a   Chevalier, Jean Marc ^a   Précigoux, Gilles ^a   Levi, Sonia ^b   Arosio, Paolo ^c  

^a UNIVERSITÉ DE BORDEAUX   (France)

^b SAN RAFFAELE HOSPITAL   (Italy)

^c UNIVERSITY OF BRESCIA   (Italy)

Author keywords

crystal structure; ferritin; ferroxidase activity; metal binding sites; mitochondria; MtF, mitochondrial ferritin; rHuHF, recombinant human H ferritin; rMtF, recombinant MtF; ROS, reactive oxygen species

Indexed keywords

ALANINE; CERULOPLASMIN; FERRITIN; IRON; IRON BINDING PROTEIN; MAGNESIUM; MANGANESE; MITOCHONDRIAL PROTEIN; MUTANT PROTEIN; RECOMBINANT PROTEIN; SERINE; ZINC;

AMINO ACID SEQUENCE; AMINO ACID SUBSTITUTION; ARTICLE; BINDING SITE; CATALYSIS; CONTROLLED STUDY; CRYSTAL STRUCTURE; ENZYME ACTIVITY; ENZYME STRUCTURE; GENE MUTATION; HUMAN; METAL BINDING; MUTANT; MUTATIONAL ANALYSIS; PRIORITY JOURNAL; PROTEIN FUNCTION; PROTEIN STRUCTURE;

EID: 2942542658     PISSN: 00222836     EISSN: None     Source Type: Journal    
DOI: 10.1016/j.jmb.2004.04.036     Document Type: Article

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